Dipodomys spectabilis (banner-tailed kangaroo rat): 122114228
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Entry
122114228 CDS
T07891
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00230
Purine metabolism
dsp00670
One carbon pool by folate
dsp01100
Metabolic pathways
dsp01523
Antifolate resistance
Module
dsp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122114228 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
122114228 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122114228 (Gart)
Enzymes [BR:
dsp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
122114228 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
122114228 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
122114228 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
LUD_dom
Motif
Other DBs
NCBI-GeneID:
122114228
NCBI-ProteinID:
XP_042543174
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MTARVLVIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSGKISNTAIPVSNHTALAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKLEEACSFIMNADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAP
QVPMDLLLEIKNTVLQRVVEGMQQEGTPYTGILYAGIMLTKGGPKVLEFNCRFGDPECQV
ILPLLQSDLYEVIQSTLDGRLSASLPIWLESHSAITVVMASKGYPGAYTKGTEITGFSEA
QALGLEVFHAGTSLKDGKVVTSGGRVLTVTAIRENLLLALEEAKKGLAVIKFEGAVYRRD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDVNTTEAVVAGVAQACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVVGIASSGLHSNGFSLVRKIVEKSSLQYSSPAPDGCGDQTLGDLLLTPTR
IYSHSLLPIIRSGHVKAFAHITGGGLLENIPRVLPPKFGVELDARSWRIPRVFSWLQHEG
QLSEEEMARTFNCGVGAALVVSKNQTEQILTAIHQRQEEAWVIGSVVACPEGSPQVKVKN
LIETMNINGSLLVNGSRKNHLPTQPKKARVAVLISGTGSNLQALIDSTLDPKSSAHIVVV
ISNKAQVAGLSKAERAGIPTKVINHKLYKSRVDFDNAVDQVLEEFSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGANAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEA
VPVKRGDTIETLSERVKLAEHKIFPAALQLVASGTVQLGKNGKICWVQEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atgacagcccgagtacttgtaattggaagtggcggaagggagcatacattggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgctctggaaagatttcaaatacagctatccccgtcagtaatcacactgcccttgctcag
ttctgcaaagatgagaaaattgagtttgtagttgttggacctgaggcacctctggctgct
ggaattgttggagacctgacctctgcaggagtacgatgcttcggccccacagcagaagca
gctcagttggagtccagcaaaagatttgccaaagagttcatggaccgacatgggatccca
actgcacgatggagagctttcaccaaacttgaagaggcctgcagcttcattatgaatgca
gacttccctgcattggtggtgaaagccagtggtcttgcagctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaggctgtacaagagattatgcaggaaaaggctttt
ggagcagctggagaaacaatcgtcattgaagaacttcttgaaggagaagaagtgtcttgt
ctgtgtttcactgatgggaagacagtggcccccatgcccccggcacaagaccacaagcga
ttactggaaggcgatcagggccccaacacaggggggatgggagcctattgtccagcacct
caggttcctatggatttgttactggaaattaagaacactgttcttcagagggtggtagaa
ggcatgcagcaagagggtacgccatatacaggaattctttatgctggcataatgctgacc
aagggcggcccgaaggttctggaatttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttcagagtgatctttatgaagtgattcagtccaccctagatggccga
ctgagtgcatctctacccatttggctggaaagccactctgccataacggttgtcatggca
agtaaaggttatcctggagcctacacgaagggtacagagataacagggttttctgaagct
caagccttaggactagaggtgttccatgctggcacttctcttaaagatggcaaagtggta
accagtgggggcagagtccttacagtgacagctatccgggagaatctcctactggccctg
gaagaagccaagaaaggacttgctgtgataaagtttgagggagcagtttatagaagggac
atcggctttcgggccatagctttcctccaacagcccaggggcctgacatacaaggaatcg
ggggtagacattgcagctggaaatatgctggttaagaaaattaaacctttagcaaaagcc
acctccagaccaggctgtgatgttgaccttggagggtttgctggtctttttgatttgaaa
gcagcaggtttcaaagatcctcttctggcctctggaacagatggtgttgggactaaactg
aagattgcccagctgtgcaataaacacgataccattggtcaagatttggttgccatgtgt
gtaaatgacattctggctcaaggagcagagcctctcttcttccttgattacttttcctgt
ggaaaacttgatgtcaatacaactgaagctgttgttgctggagtggctcaagcttgcaga
caagctggatgtgctcttcttggaggagaaacagcagaaatgcctgacatgtatcctccg
ggcgagtatgatctggctggttttgccgttggtgccatggagcgggatcagaaactcccc
cacctagagaggatcactgaaggcgatgttgttgttggaatcgcctcatccggtcttcac
agcaatggctttagccttgtgaggaaaatagtggagaaatcttccctccagtactcctct
ccagcacctgatggttgtggtgaccagactctaggggatctgctcctaactccaactaga
atctacagccattcactgttacccatcatccgttcaggacatgtcaaagcctttgctcat
attactggtggaggactgctagaaaacattcccagagtactgcctccgaaattcggggta
gaattggatgcccgtagctggaggatccctagggtcttctcatggttacagcatgaagga
cagctctcagaagaagagatggccagaacctttaactgtggagttggagcagctcttgtg
gtgtcaaagaaccaaacagaacaaattctgactgcgattcatcagcgtcaggaagaagcc
tgggtgatcggcagtgtggtcgcatgtcctgaaggttcccctcaagtgaaagtcaagaat
cttattgaaaccatgaacataaatgggtcattgttggtgaatggctctcggaaaaatcat
ctccccacccaaccaaagaaggcaagagtggctgtcctaatatctggaacaggatcgaac
ctccaagcactcatagacagtactctggatccaaagagctctgcacacattgttgttgta
atctccaacaaagcccaagtggctgggttgagcaaggcagagagagctggtattcccacc
aaagtaataaatcataaattatacaaaagtcgtgtcgattttgacaatgcagttgaccaa
gtccttgaagagttttccacagacatagtctgtcttgcaggattcatgagaattctctct
ggcccctttgtcagaaaatgggatgggaaaatgctaaacatccacccatctttgctccct
tcatttaagggtgcaaatgctcatgagcaagttctggaagctggagtcacaattactggg
tgcacagtacactttgtagctgaagatgtagatgctggacagatcattttacaagaagct
gttccagtgaagaggggtgacaccattgaaactttgtctgaaagagtaaaattagcagaa
cacaaaatatttcctgcagccctccagctagtggccagcggaactgtacagcttggaaaa
aatggcaagatctgctgggtccaagaggaatga
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