| Entry |
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|---|
| Symbol |
Ubr4
|
|---|
| Name |
(RefSeq) E3 ubiquitin-protein ligase UBR4 isoform X1
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|---|
| KO |
|
|---|
| Organism |
dsp Dipodomys spectabilis (banner-tailed kangaroo rat)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:dsp00001]
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
122115217 (Ubr4)
09172 Infectious disease: viral
05165 Human papillomavirus infection
122115217 (Ubr4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:dsp04121]
122115217 (Ubr4)
Enzymes [BR:dsp01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
122115217 (Ubr4)
Ubiquitin system [BR:dsp04121]
Ubiquitin ligases (E3)
Single Ring-finger type E3
UBR box proteins
122115217 (Ubr4)
|
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
|
|---|
| AA seq |
5183 aa
MATSGGEEATAAAPAAAPASPVTGADTAPGWEVAVRPLLSASYSAFEMKELPQLVASVIE
SESEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENP
DEACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELAS
LVNPELRQKEVQMNFLNQLTSVFNPRTVASPPISPQALVEGENDEQSSTDQASAIKTKNV
FIAQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNG
FHSLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVGSAQQV
RTGSTSSKEEDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSL
FLILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILAN
HAIKLLTSLFQDLQVEALHKGWESDGPPAVLSIMAQSTSIQRIQRLIDSVPLMNLLLTLL
STSYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEET
ISPSKEKVAPPPPPPPPPLESSPRVKSPSKQAPGDKGNILASRKDPELFLGLASNILNFI
TSSMLNSRNNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGSSDEEFAAALYHFNHSLV
TSDLQSPNLQNTLLQQLGVAPFSEGPWPLYIHPQGLSVLSRLLLIWQHKAGTQGDPDVPE
CLKVWDRFLSTMKQNALQGVVPSETEDLNVEHLQLLLLIFHNFSEKGRQAILTLFVQNIQ
ELSVNMEAQMRSVPLILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWANGSQDS
NSRRPATPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFS
KLVKYDELYTALTALLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKT
YMNQLAMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAENAGSLIELASTK
CSSVKYDVEIVEEYFARQISSFCSIDCTTILQLHELPSLQSIYTLDAAISKVQVSLDEHF
SKMAAETDPHKSSEITKNLLPATLQLIDTYASFTRAYLLQNFNEEGATEKPSKEKLQGFA
AVLAIGSSRCKANTLGPTLVQNLPSSVQAVCESWNTINTNEFPNIGSWRNAFANDTIPSE
SYISAVQAAHLGTLCGQSLPLAASLKHTLLSLVRLTGDLIVWADEMNPPQVIRTLLPLLL
ESSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEE
CLQYLEKQLESSQARKAMEEFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTE
KSPNPSLLHLCGSLAQLACVEPVRLQAWLTRMTTSPPKDSDQLDIIQENRQLLQLLTTYI
VRENSQVGEGVCAVLLGTLTPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHNA
AVDWLGRCKKYLSQKNVVEKLNANVMHGKHVIILECTCHIMSYLADVTNALSQSNGQGPS
HLSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHC
HTCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSST
MKESAFQSEPRVSESLVRHASTSPADKAKVTISDGKVTDEEKPKKSSLCRTVEGCREELQ
NQANFSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALGELHTVDKVVEMTDQLMV
PTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGK
ITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTF
SSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFL
LPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLK
DSNSQLAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRTSMEVVQLFPINIKSSNGGSKT
SPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRHT
ACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITTR
TSSQVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIEI
SNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADKK
LNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPSASVSNICPSNLNQSNGTV
DSDSATPTTTSGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPAS
VQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVITARSI
AIMRPNNLVHFTESKLPQMETEGVDEGKEPQKQAEGECCSFITQLVNHFWKLHASKPKNA
FLAPACLPGLTHIEATVNALVDIIHGYCTCELDCINTASKIYMQMLLCPDPAVSFSCKQA
LIRVLRPRNKRRHVTLPSSPRSNTPMGDKDDDDDDDADEKMQSSGITDGGHIRQESQEQS
EVDHGDFEMVSESMVLETAENVNNGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAI
ALSLQQDQQGSSSSALGLQSLGLSGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGS
TLRTSPADHGGSVGSESGGSAVDSVAGEHSVSGRSSAYGDATAEGHPAGPGSVSSSTGAI
STATGHQEGDGSEGEGEGEAEGDVHTSNRLHMVRLMLLERLLQTLPQLRNVGGVRAIPYM
QVILMLTTDLDGEDEKDKGALDNLLSQLIAELGMDKKDVSKKNERSALNEVHLVVMRLLS
VFMSRTKSGSKSSICESSSLISSATAAALLSSGAVDYCLHVLKSLLEYWKNQQNDEEPVA
TSQLLKPHTTSSPPDMSPFFLRQYVKGHAADVFEAYTQLLTEMVLRLPYQIKKIADTSSR
IPPPVFDHSWFYFLSEYLMIQQTPFVRRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGI
KKLLEEQGIFLRASVVTASSGSALQYDTLISLMEHLKACAEIAAQRTINWQKFCIKDDSV
LYFLLQVSFLVDEGVSPVLLQLLSCALCGSKVLAALAASTGSSSSASSSAPVASSSGQGA
TQSKSSTKKSKKEEKEKEKDSESSGSQEDQLCTALVNQLNKFADKETLIQFLRCFLLESN
SSSVRWQAHCLTLHIYRNSSKSQQELLLDLMWSIWPELPAYGRKAAQFVDLLGYFSLKTI
QTEKKLKEYSQKAVEILRTQNHILTNHPNSNIYSTLSGLVEFDGYYLESDPCLVCNNPEV
PFCYIKLSSIKVDTRYTTTQQVVKLIGSHTISKVTVKIGDLKRTKMVRTINLYYNNRTVQ
AIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLPIVASNLMIEFADFYENYQASTETLQC
PRCSASVPANPGVCGNCGENVYQCHKCRSINYDEKDPFLCNACGFCKYARFDFMLYAKPC
CAVDPIENEEDRKKAVSNINTLLDKADRVYHQLMGHRPQLENLLCKVNEAAPEKPQEDSG
TAGGISSTSASVNRYILQLAQEYCGDCKNSFDELSKIIQKVFASRKELLEYDLQQREAAT
KSSRTSVQPTFTASQYRALSVLGCGHTSSTKCYGCASAVTEHCITLLRALATNPALRHIL
VSQGLIRELFDYNLRRGAAAMREEVRQLMCLLTRDNPEATQQMNDLIIGKVSTALKGHRA
NPDLASSLQYEMLLLTDSISKEDSCWELRLRCALSLFLMAVNIKTPVVVENITLMCLRIL
QKLIKPPAPTSKKNKDVPVEALTTVKPYCNEIHAQAQLWLKRDPKASYEAWKKCLPIRGI
EGNGKSPSKSELHHLYLTEKYVWRWKQFLSRRGKRTTPLDLKLGHNNWLRQVLFTPATQA
ARQAACTIVEALATIPSRKQQVLDLLTSYLDELSIAGECAAEYLALYQKLIASAHWKVYL
AARGVLPYVGNLITKEIARLLALEEATLSTDLQQGYALKSLTGLLSSFVEVESIKRHFKS
RLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLEMLEDMTTGTESETKAFMAVCIETAKRY
NLDDYRTPVFIFERLCSIIYPEENEVTEFFVTLEKDPQQEDFLQGRMPGNPYSSNEPGIG
PLMRDIKNKICQDCDLVALLEDDSGMELLVNNKIISLDLPVAEVYKKVWCTTNEGEPMRI
VYRMRGLLGDATEEFIESLDSTTDEEEDEEEVYKMAGVMAQCGGLECMLNRLAGIKDFKQ
GRHLLTVLLKLFSFCVKVKVNRQQLVKLEMNTLNVMLGTLNLALVAEQESKDSGGAAVAE
QVLSIMEIILDESNAEPLSEDKGNLLLTGDKDQLVMLLDQINSTFVRSNPSVLQGLLRII
PYLSFGEVEKMQILVERFKPYCNFDKYDEDYSGDDKVFLDCFCKIAAGIKNNSNGHQLKD
LILQKGITQNALDYMKKHIPSAKNLDADIWKKFLSRPALPFILRLLRGLAIQHPATQVLI
GTDSITNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMR
QKALGTLGMTTNEKGQVVTKTALLKQMEELIEEPGLTCCICREGYKFQPTKVLGIYTFTK
RVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKCNGLL
PVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGG
GGRESNIHLIPYIIHTVLYVLNTTRATSREEKNLQGFLEQPKEKWVESAFDVDGPHYFTV
LALHVLPPEQWRAMRIEILRRLLVTSHARAVAPGGATRLTDKAVKDYSVYRSSLLFWALV
DLIYNMFKKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADRALKTFQEEFMPVEAFPEFFD
AAGLLSEVTDPENFLKDLLNSVP |
|---|
| NT seq |
15552 nt +upstreamnt +downstreamnt
atggcgacgagcggcggtgaagaggcgacggcagcggcgccggcagcggcgcctgcgtcc
ccggtgaccggggcagacacagctccgggctgggaggtggcggtacggcccctgctgtcc
gcgtcctactcggccttcgagatgaaggagttgccgcagctggtggcctcagtcatcgag
agtgaatcagaaatcctgcaccatgagaagcagtatgagccattctactcatcctttgtc
gccctctccactcactacattaccacagtttgcagcctcattccacggaaccaacttcag
tcggtggcagcagcctgtaaagttctaattgagttttctcttctgcgtctggagaatcca
gatgaagcgtgtgctgtgtcccagaaacacttgattctcctaatcaaaggcctctgcact
ggttgtagccgactagacagaactgaaattatcaccttcacagccatgatgaaatcggcc
aaactgccacagacagtgaagaccctttccgatgtggaagatcagaaagagctggcctca
ctggtgaaccctgagctgaggcagaaggaggtgcagatgaattttttgaaccagctgacc
tcagttttcaaccctagaactgtggcatcaccacccattagtccacaggctctggtggaa
ggggaaaatgatgagcagtcatccacagatcaagcctctgctatcaagaccaagaacgtg
tttatagctcagaatgtggccagtcttcaagagcttggtggttcagagaagttactgcgt
gtgtgtttgaatctgccatatttcctacgctacatcaatcggttccaagatgcagtgtta
gccaattccttctttatcatgcctgcaacagtggcagatgccactgctgtccgtaatggt
tttcattcactggtgattgatgtaactatggcattggataccctttctctacctgtgttg
gaacctctcaatccttctcgtttacaagatgtaacagtcctcagcctaagctgtctgtat
gcaggtgtgagtgtggcaacatgtatggccattcttcatgtgggcagtgctcagcaagtg
cgtacaggatccacaagctccaaagaagaagactatgaaagtgatgcagctacaattgtc
cagaaatgtcttgaaatctatgacatgattggacaagccatcagcagttcccgcagggca
ggtggcgagcactaccagaactttcagttgttgggtgcctggtgtttgctgaacagcctt
ttcctcatactgaacctcagtcctactgccttggctgataaggggaaagagaaagaccca
ctagctgctctccgagtgagagacattctttctcgtacaaaagagggagtgggctctccc
aagctggggcctggcaaagggcatcagggctttggggtgctctcagtcatattagcaaac
catgccatcaagctattgacatctttgtttcaagacctgcaggtggaggctctacacaag
ggttgggagtctgatggtccccctgcggtcctaagcattatggcccagagcacctccata
cagaggattcaacggctgatcgactctgtcccactgatgaacttactactgacattactc
tcaacttcatacagaaaggcatgtgtcctacagcggcagaggaagggctccatgagcagt
gatgccagtgcctccaccgactctaacacctactatgaggacgatttcagcagtaccgag
gaggacagcagtcaagatgatgacagtgagcctattttggggcagtggttcgaggagacc
atctctcccagtaaagagaaagtggcgcctccacctccacccccgccccctccgctggag
agctctcctcgggttaaaagccccagtaagcaggcccctggtgacaagggcaacattttg
gctagtcgaaaagatcctgagttgtttctaggtctggcttccaacattttgaacttcatt
acctcttccatgctaaactctcggaacaatttcatccgaaactatctgagcgtgtctctt
tccgaacaccatatggccaccctggccagtatcatcaaggaggtggacaaagatggactc
aagggttcatcagatgaagagtttgctgctgctctctatcacttcaaccactctctggtg
acctctgacctccagtccccaaatctccagaacacactgctgcagcagctgggagttgct
cccttttctgagggcccttggcccctttacattcacccgcaaggcctctctgtgctttca
cgcctcctgctcatctggcagcataaagctggcacgcaaggtgaccctgatgtccctgaa
tgccttaaagtttgggacaggtttttgtctacaatgaagcagaatgccctacaaggggta
gtgcccagtgagacagaagatctgaatgtagaacacctgcagctgctactcctcattttc
cacaacttttctgagaaaggccggcaggccattttgaccctctttgtccagaatatccag
gagctgagcgtcaacatggaagcacagatgcgctctgtgcctctcatcctggcacgcctc
cttttgatctttgactatctgcttcatcagtactccaaagcacccgtttatctgtttgag
caggtgcagcataacctcctcagtcctccttttggatgggcaaatggatcccaggacagt
aacagccgcagaccagctacccctctgtatcatggattcaaggaagtagaagaaaactgg
tctaagcatttctcatcagatgctgtccctcaacccagattctactgtgtcctgtcccca
gaagcctcagaggatgatttgaaccgtcttgattctgtggcatgtgacgttcttttctcc
aagcttgttaagtatgatgagctttatactgccctaacagccttgcttgcagctgggtcc
cagcttgatactgtaaggaggaaggaaaataagaatgtgacagctctggaggcctgtgct
cttcagtactatttcttgatactgtggaggatcctaggaattttgccaccttcaaagact
tacatgaaccagctggccatgaactcacctgagatgagtgaatgtgacatcttacacaca
ctacgctggtcatcccgcctccgtatcagctcctatgtcaattggataaaggatcacctc
atcaaacagggaatgaaggctgaaaatgctggctctctcatagaactggcgtctaccaag
tgtagctcagtgaaatatgatgttgaaattgttgaggaatacttcgctcgacagatctcg
tcattctgtagcatcgactgtaccaccatcttgcagctccatgaacttcctagtctgcag
tccatctacaccctcgatgctgctatctccaaggtccaggtctctttggatgaacacttt
tcaaagatggctgcagagacggatccacataagtcatctgagatcacaaagaatctcctt
ccagccacactccaactcattgacacctatgcatcattcactagagcctatttgttacag
aacttcaatgaggagggagccactgaaaaaccttccaaagagaaactgcagggctttgct
gctgtcttagctattggctccagtaggtgcaaggcaaatactctgggtccaaccctggtt
cagaatttgccatcatcagtgcaagctgtatgtgagtcctggaatactatcaatactaat
gagtttcccaacattggatcctggcgcaatgcttttgccaatgataccattccttctgag
agttacatcagtgctgtgcaagctgctcacttgggaactctttgtggccagagtctgcct
ctggctgcttccttgaagcatactcttctctcgctggttaggctgactggagacctgatt
gtgtgggcagatgagatgaacccaccacaggtcattcggaccctgctaccccttcttttg
gagtccagcactgagagtgttgctgagatcagtagcaactccctggaacgcatcctaggc
cctgcagaatctgatgagttcctggctcgtgtttatgagaagctgatcactggttgctac
aacattctggccaatcatgcagaccccaacagtggactggatgagtctatcttggaggaa
tgtcttcaatatttggaaaagcaattagaaagtagccaggcccgtaaagccatggaagaa
ttcttctcagacagtggcgaacttgtgcagatcatgatggccacagccaatgagaacctt
tctgctaaattctgtaaccgagtcttgaaattcttcaccaaactcttccagctgactgag
aagagccctaacccgagccttctgcatctctgtggctcattggcacaactggcttgtgtg
gagcctgtgcgtttgcaggcctggctcacccggatgactacatcacccccaaaagattct
gatcagctggatataattcaggagaaccggcagctgttgcagttactgaccacgtacatt
gttcgggaaaacagccaagttggagaaggcgtgtgtgctgtccttctgggcaccctgact
cccatggcaacagagatgctggccaatggtgatgggactggctttcctgaactcatggtt
gtgatggccaccctggccagtgctggtcaaggtgctggtcaccttcagcttcataatgct
gctgtggactggttgggcagatgcaagaaatacctgtcacagaagaatgtggttgagaaa
ctgaatgccaatgtaatgcatggaaagcacgtgataatcttggagtgcacatgccatatt
atgtcttacttggctgatgtcacaaatgccctaagccagagtaatggtcaaggcccaagt
cacctgtcagtggacggggaagagcgagccattgaggtagactcagactgggtggaggag
ttggcagtggaagaggaagattcacaggctgaggactcagatgaagattctctttgcaat
aaactctgcacttttaccatcacacagaaagaattcatgaaccagcattggtaccactgt
catacctgcaaaatggtggatggagtaggtgtgtgcacagtgtgtgctaaggtgtgccac
aaggaccatgagatttcttatgccaagtatggatccttcttctgtgactgtggagccaag
gaagatggaagctgtttggcactggtaaaaagaactccaagcagtggcatgagctccacc
atgaaggagtctgcatttcagagtgaaccaagggtttcagagagtttggttcgccatgct
agcacttcaccagccgacaaggccaaggtcaccattagtgatggaaaggtcactgatgaa
gagaagcccaagaagagtagcctgtgccgcacagtagaaggttgccgagaagagctacag
aaccaggccaatttctccttcgctcctctcgtgttagacatgctcaatttcctcatggat
gccattcagaccaactttcaacaggcttcggctgtggggagcagcagccgggcacagcag
gcccttggtgaactgcatacagtggacaaggtggttgagatgacagaccagctgatggtt
cccaccttaggctcccaggaaggtgcctttgagaatgtacggatgaattacagcggagac
cagggccagactatacggcagctaatcagcgcccacgtgctcaggcgggtggccatgtgt
gttctgtcttctccacatgggcgccgccagcacttggctgtcagccatgagaagggcaag
atcacagttctgcagctctctgcacttttgaagcaagcagactccagcaaaaggaagttg
actctgacccgcttggcttctgcccctgtgccctttactgtgctgagccttactggaaat
ccctgcaaggaagattacctggcagtgtgtggcttgaaggactgccatgtgctcaccttt
agtagctcgggttcagtttcggatcacttggtgttgcaccctcagttggcaacagggaac
ttcatcatcaaagccgtgtggctacctggttcacagactgagttagcaattgttacagca
gactttgtgaagatttatgacctatctgtggatgctttgagtccaaccttctacttcctc
ctgccaagttcgaagataagagatgttaccttccttttcaatgaggaggggaagaacatc
attgtgataatgtcttcagctgggtacatctatactcagctcatggaggaggccagcagt
gcccagcaaggacccttctatgtcacaaacgtactggaaatcaatcatgaagatctgaag
gatagtaacagccagctggcaggtggtggtgtatctgtgtactactcccacgtgttacag
atgctgttcttcagttattgtcagggaaagtcctttgcagccaccatcagcagaacaagc
atggaggtggtgcagctcttccctatcaacattaaaagttccaatggtggcagtaagact
tctcctgctctctgccagtggtctgaggtgatgaaccatcctggcttggtgtgttgtgtg
cagcaaacaacaggtgtgcctctggttgttatggtgaaaccagacacttttctaatccag
gagattaagactcttcctgcgaaagcaaagatccaagacatggttgctattagacataca
gcctgcaatgagcaacagcggacaaccatgatcttgctgtgtgaggatggcagcttgcgc
atttacatggccaatgtggagaacacttcttactggctccagccgtccttgcagcccagc
agtgtaatcagcatcatgaagcctgttcgaaagcgcaaaacagctacaattacaacccgc
acatctagccaggtgaccttccccattgacttctttgaacacaaccagcagctgacagat
gtggagttcggtggtaatgatctcctgcaagtctacaatgcacaacagataaagcaccgg
ctgaactctactggcatgtatgtggctaacaccaagcctggtggcttcaccattgagatc
agtaacaacaacagcactatggtgatgacaggcatgcggatccagatcgggacccaggca
attgaacgggccccatcatatatcgagatttttggcagaaccatgcagcttaatctgagt
cgatcacgctggtttgacttcccctttaccagagaagaagccctgcaagctgataagaag
ctgaacctctttattggtgcctcagtggatccagcaggtgtcaccatgatagatgctgta
aaaatttatggcaagactaaggagcaatttggctggcctgatgagccccctgaagaattc
ccttctgcctctgtcagcaacatctgcccttccaacctcaaccagagtaatggcactgta
gacagcgactcagctacacctactacaactagtggcactgtcttggagaggctggttgtg
agttctttagaagccctggaaagctgctttgccgttggtccaatcatcgagaaggagagg
aacaagaatgcagcacaggagctggccactttgctgctgtccctgccagcacctgctagt
gtacagcagcagtccaagagtcttttagccagcctgcatactagtcgctcagcctatcac
agccacaaggatcaggccttgctgagcaaagctgtgcagtgtctcaacacatccagcaaa
gaaggcaaggacttggaccctgaagtcttccagaggctggtcatcacagctcgatccatt
gccatcatgcgtcctaacaaccttgtccattttacggagtcaaagctgccccagatggaa
acagaaggagtggatgaggggaaggaaccacagaagcaggcagaaggagaatgctgtagt
ttcatcacgcagcttgtgaaccacttctggaaactccatgcatccaaacccaagaatgcc
ttcctggcccctgcctgcctgccaggtctcactcatattgaagctactgttaatgcattg
gtagatattatccatggctactgtacttgtgagctggactgtatcaatacagcatccaag
atctacatgcagatgctgttgtgtcctgatccggctgtgagcttctcttgcaaacaagct
ctaattcgagtcctaaggcccagaaacaaacggagacatgtaacattgccctcctcccct
cgaagtaacactccaatgggagacaaggatgatgacgatgacgatgatgcagatgagaaa
atgcagtcctcagggatcaccgatggtggtcacatccgccaggaaagccaggaacagagt
gaggtggaccatggcgattttgaaatggtgtctgagtcaatggtcctggagacagctgaa
aatgtcaacaatggcaacccctctcccctggaggctctgctggcaggtgcagagggcttc
ccacccatgctggacatcccacctgatgcagatgatgagaccatggttgaactagccatt
gccctgagcctgcagcaggaccaacaaggcagcagcagcagtgccctgggcctgcagagc
ctgggactgtccggccaggcacccagctcttcctctctggacgcaggaaccctctctgac
accacagcatcagctccagcttctgatgacgagggcagcacggcagcaacagatggctcc
accctgcggacctctcctgccgaccatggtggcagtgtgggctcggagagcgggggcagt
gcagtggactcagtggctggcgagcacagtgtgtctggccggagcagtgcctatggggat
gccacagcggaagggcatcctgctggaccaggaagtgtcagctcaagcactggtgctatt
agtactgccactgggcaccaggagggagacggctccgagggagaaggagaaggggaagct
gaaggagatgtccataccagcaacaggctgcacatggtgcgcctgatgctgttggagagg
ttactgcagaccttgccccagttacgaaatgttggaggtgtccgggccatcccatacatg
caggtcattctaatgcttactacagatttggatggagaagatgagaaagacaagggagct
ttggacaaccttctctcccagctgattgctgaactgggtatggataaaaaggatgtgtcc
aagaagaatgagcgcagtgctttgaatgaagtccatttggtagtgatgaggcttcttagt
gtcttcatgtcccgcacgaagtctggatccaagtcttccatatgtgagtcatcttccctc
atctctagtgccacagctgcagccctgctgagctcaggggctgtggactattgcctgcat
gtgctcaagtcactgctggaatattggaagaaccaacagaatgatgaagaacccgtggcc
actagccagttgctgaaaccccatacaacttcatcccctcctgatatgagcccattcttt
ctccggcagtatgtgaagggtcatgctgctgatgtgtttgaggcctatactcagctgctc
acagagatggtcctgcggttgccataccaaatcaaaaagatcgctgacaccagttctcga
atcccacctcctgtctttgatcactcatggttctattttctctcagagtacttgatgatc
cagcagactccatttgtacgccgccaagtccgaaaacttctgctcttcatctgtggatca
aaggagaagtaccgacaactccgggatttgcacaccttggactctcatgtgcgtgggatc
aagaagctgctagaggaacagggaatatttctccgggccagtgtggttacagccagttca
ggctctgccttgcagtatgacacactcatcagcctgatggaacacctgaaagcctgtgca
gagattgctgcccagcgaaccatcaactggcagaaattctgcatcaaagatgactctgtc
ctgtacttcctcctgcaagtgagtttcctggtggatgagggtgtgtccccagtgctgctg
cagctgctctcctgtgctctgtgtggcagcaaagtgctcgcggccctggcagcctccaca
ggttcctccagttccgcttcctcctctgctcctgtggcttccagctctggacaaggcgca
acacagtccaaatcttccacgaaaaagagcaaaaaagaagaaaaggaaaaagaaaaagat
agtgagagttcaggtagccaggaggaccagctgtgcacagctctggtgaaccagctgaac
aaatttgctgataaggaaaccctcatccagtttctgcgttgtttcctgttggagtccaat
tcttcttctgtgcgctggcaggcccactgcctgacgctgcacatctacagaaactccagc
aaatctcaacaggagctcttgctagatctcatgtggtccatttggccagaactcccagct
tatggtcgtaaggctgcccagtttgtggatctactgggatatttctccttgaaaacaata
cagacagagaagaagttgaaggagtattcacagaaggctgttgagatacttcggactcaa
aaccatattctcaccaaccatcccaactccaacatttacagcaccttgtccggcttagtg
gagttcgatggctattatctggagagtgatccctgtctggtgtgtaacaatccagaagtg
ccattttgttatatcaagctgtcttccattaaagtggatacacgatacaccaccacccag
caggttgtgaagctgattggcagtcacaccatcagcaaagtgacagtgaagattggggac
ctaaagcggaccaagatggtgcggactatcaatctgtattataacaaccgaactgtgcag
gccatcgtggagttgaaaaacaaaccagcccgctggcacaaagcaaagaaagttcagctg
acccccggtcagacagaagtgaagattgacctgccgttgcccattgtggcctccaacctg
atgattgagtttgcagacttctatgaaaactaccaggcatccacagagaccctgcagtgc
ccacgctgtagtgcctctgttcctgctaatccaggggtgtgtggcaactgtggagagaat
gtgtaccagtgtcacaaatgcagatccatcaactatgatgaaaaggatcctttcctctgc
aatgcttgtggcttctgtaaatatgctcgctttgacttcatgctctacgccaagccttgc
tgtgcagtggatcccattgaaaatgaggaagaccggaagaaggctgtttccaacataaac
acacttctggacaaagctgaccgagtatatcatcaattgatgggacataggccacagctg
gagaacctgctatgcaaagtgaatgaggccgctccagaaaagccacaggaagactctgga
acggcagggggcatcagttccacatcagccagtgtaaatcgctatatcctgcagttggct
caggagtactgtggtgactgcaagaactcatttgatgaactctccaaaatcatccagaaa
gtctttgcttcacgcaaggagttgttggaatatgacctgcagcaaagggaagcagccacc
aaatcatcccggacttctgtgcagcccacattcactgccagccagtaccgcgctttatcc
gtcctgggctgtggccacacatcttccaccaagtgctatggctgtgcttctgccgtcacc
gagcattgtatcacactcctcagggccctggccaccaatccagctctgcgacatatcctt
gtctcccagggccttatccgggaactcttcgattataatcttcgccgaggagctgcagcc
atgcgggaggaggtccgccagctcatgtgcctcctaactcgagataatccagaagccacc
cagcagatgaatgacctgatcattggcaaagtctctacagctctgaaaggccatcgggcc
aaccctgacttggcaagtagtctgcagtatgagatgctgctgctgacagattccatctcg
aaggaggatagctgctgggagctccgtttacgctgtgcgctgagccttttcctcatggct
gtgaatattaagactcctgtggtagtcgagaacatcaccctcatgtgcctgaggatcttg
cagaagcttattaagccacctgccccaaccagcaagaagaacaaggatgtccctgtcgag
gccctcaccactgtgaagccatactgcaatgagatccatgcccaggctcagctgtggctc
aagagagatcccaaggcatcctatgaagcctggaagaagtgtcttcctattagagggata
gaaggcaatgggaagtctcccagcaagtcagagcttcaccatctctatttgactgagaag
tacgtatggaggtggaaacagttcctgagccggcgagggaagagaaccactcctctggat
ctcaaactggggcataacaactggttgcgacaagtgctttttactcctgcaacacaggct
gcccggcaagcagcttgtaccattgtggaggctttggccaccatccccagccgcaagcag
caggtccttgacctcctcaccagctatctggacgagctgagcatagctggggaatgtgct
gctgagtacctggctctctaccagaagcttatcgcctcagcacactggaaggtctacctg
gcagctcggggagttctgccctacgtaggcaacctcatcaccaaggaaatagcccgcttg
cttgccctggaggaggccaccctgagcactgacctgcagcagggatatgccctcaagagt
ctcacaggccttctgtcttccttcgtggaggtggaatccatcaaaaggcactttaaaagt
cgcttggtgggaaccgtgctgaatgggtacctgtgcttgcggaagctggtggtgcagagg
accaagctgatagatgaaacccaggacatgctgctggagatgctggaagacatgaccaca
ggtacagaatcagaaaccaaagccttcatggctgtatgcattgagacagccaagcgctac
aatctggacgactaccgaacaccagtcttcatctttgagaggctgtgcagcatcatttat
cctgaggagaatgaagtcactgaattctttgtgaccctggagaaggacccccaacaagaa
gatttcttacagggcaggatgcctgggaatccatatagcagcaatgagccgggcattggg
ccacttatgagagatataaagaacaagatttgccaggactgtgacctggtggctctcctg
gaggacgacagtgggatggagcttctagtgaacaataaaattattagtttggacctacct
gtggctgaagtttacaagaaggtctggtgtaccacgaatgagggagagcccatgagaatt
gtttatcgaatgcggggcctgctgggtgacgccactgaggagttcatcgagtctctggac
tctaccacagatgaagaagaagatgaagaagaagtgtacaagatggctggtgtgatggcc
cagtgtgggggcctggagtgcatgcttaacagattggcagggatcaaagacttcaagcag
gggcgccaccttctaacagtgctgctgaagttgttcagtttctgtgtgaaggtgaaagtc
aaccggcagcagttggtcaagctggagatgaacactttgaatgtcatgctagggacgcta
aacttggctctggtagcagagcaggagagcaaggacagtgggggtgctgctgtggctgag
caggtgctcagcatcatggaaatcattctagatgagtccaatgcggagcccctgagtgag
gacaagggcaacctcctcctcacgggtgacaaggaccaactcgtgatgctcttggaccag
atcaacagcaccttcgtccgctctaaccctagcgtgcttcagggcctgctgcgcatcatc
ccgtacctctcctttggagaggtggaaaagatgcagatcttggtggagcggttcaaacca
tactgcaactttgataagtatgacgaagactacagtggtgatgacaaagtcttcctggac
tgcttctgcaagattgcagccggcattaagaacaacagcaatgggcatcagctgaaggac
ctcatcctccagaagggaatcactcagaatgccctggattacatgaaaaagcacattcct
agtgctaagaatttggatgctgacatctggaaaaagtttttatctcgcccagccctgcca
tttatcttgaggcttcttcgggggctagccatccaacacccagctacccaggttctgatt
ggaactgactccatcacaaatctgcataaactggagcaggtgtccagtgacgagggcatt
gggaccttggcagagaacctactagaggcactgcgggaacacccggatgtgaacaagaaa
attgatgcagcccgcagagagacccgagcagagaaaaagcgcatggccatggctatgaga
cagaaggcactggggaccctaggcatgacgaccaatgaaaagggccaggtagtgaccaag
acagcgctcctgaagcagatggaggagctgatcgaggagccaggcctcacatgctgcatc
tgcagagaaggctacaagtttcagcccaccaaggtcctgggcatttatacctttactaaa
cgggtggccttggaggagatggagaataagcctcggaaacagcagggctacagcaccgtg
tcccacttcaacattgtgcactacgactgtcatttagctgctgtcaggttggctcgaggc
cgggaagagtgggaaagtgctgccctgcagaatgccaacactaagtgcaatgggctcctt
cctgtctggggtccccacgtccctgaatcagcttttgccacttgcttggcaaggcataac
acatacctccaggaatgtaccggccagcgggagcccacgtaccagctcaacatccacgac
atcaaactgctcttcctacgcttcgccatggagcagtcgttcagtgcagatactggaggg
ggaggccgggagagcaacattcacctgatcccatacatcattcacactgtgctttacgtc
ctgaacacaacacgagcaacgtctcgagaagagaagaatctccaaggtttcctggaacag
cccaaagagaagtgggtggagagtgcctttgacgtggacgggccccactatttcacggtg
ctggcccttcacgtcctgccccctgagcagtggagagcgatgcgcatagagatcctgcgg
aggctactggtgacctcacacgcccgggcagtggctccagggggagctactaggctgaca
gataaagcagtgaaggattattctgtttatcgctcttcccttctcttttgggccctcgtc
gatctcatttacaacatgtttaagaaggtgcctaccagtaacacagagggcggctggtcc
tgctctctggctgagtacatccgccacaacgacatgcccatctacgaagccgccgacaga
gccctgaaaaccttccaagaggagttcatgccagtggaggccttcccagagttcttcgac
gcagctggtcttctgtcagaagtcactgacccagagaacttcctgaaggacctgttgaac
tcggtcccctga |
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