KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122115929
Entry
122115929         CDS       T07891                                 
Symbol
Plce1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00562  Inositol phosphate metabolism
dsp01100  Metabolic pathways
dsp04014  Ras signaling pathway
dsp04015  Rap1 signaling pathway
dsp04020  Calcium signaling pathway
dsp04024  cAMP signaling pathway
dsp04070  Phosphatidylinositol signaling system
dsp04919  Thyroid hormone signaling pathway
dsp04933  AGE-RAGE signaling pathway in diabetic complications
dsp05205  Proteoglycans in cancer
Module
dsp_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    122115929 (Plce1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    122115929 (Plce1)
   04015 Rap1 signaling pathway
    122115929 (Plce1)
   04020 Calcium signaling pathway
    122115929 (Plce1)
   04070 Phosphatidylinositol signaling system
    122115929 (Plce1)
   04024 cAMP signaling pathway
    122115929 (Plce1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    122115929 (Plce1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122115929 (Plce1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    122115929 (Plce1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dsp04131]
    122115929 (Plce1)
Enzymes [BR:dsp01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     122115929 (Plce1)
Membrane trafficking [BR:dsp04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    122115929 (Plce1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    122115929 (Plce1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like
Other DBs
NCBI-GeneID: 122115929
NCBI-ProteinID: XP_042545471
LinkDB
Position
Unknown
AA seq 2293 aa
MTSEEMAASVLTPMTQRKAESAQAVADERNEKVSDISIPKVHGIKQSRQIPISQWDNLKE
ESSGSSLPKVLSVAREKIVSDENLNEKCWEKSTADSVKNLNTNRSCILGNHQRVLPQSQF
YETCNSVIEEGLCLETGIPSPLERDVFPGIQLEIARSPLGMNPLVNHPGIIDTNRSHSES
NMAVFRLHYEVDRRMSDTFHTLSENLILDDCGNCIPLPVGEEKKHYMAYTCKLMELAQTC
GNKNGQLQCEHCDPLSDEYLCFQGQKVNVVCPTESFCREDFKENPPAKTFLSHLEDFPGN
CEDVEDFFKGRKERSTLLIRRFCKNDREVKKSVYTGTRAIVRTLPSGRIGLVAWSYVDQK
RHGFLLPCGRDMAPPSKVDTRQGRSQCLPEGQWYLIYNAVRRREETEDIVGSLLHFFTKL
SASKTVHGTIHVWPCVKQCVRDTTCEFRATSQRTSLSQYITGSLLEATTSLGARSCLLST
FGGSTGRMMLKERQPGSSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILTEQEQNI
YRKVLPVDYLCFLTRDLGTQECQRSLPCLKASISASILTSQSGEHNALEDLVMRFNEVSS
WVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQS
DIETMRSLKDAMAQHESSLEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLLKL
CPRYNSQEEALEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRSLETEEE
DSASEGDSSRKNSLKDKTRWQFIIGDLLDSENDIFERSKECDPHRSEEAQKAFDHGTELI
PWYVLSIQADVHQFLLQGATVIHYDQDSHLSARCFLQLQPDNSTLTWIKPPTASPASAKA
KCGVLSNTAEPGKFPLLGNTGLSGLVEGVLDLFSAKAVYMGHPGIDIHTVCVQNKLGGMI
LSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRRFPDQRQQWLRKQ
YVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKNAEKPNMQRNNTLGISATKK
KKKILMRGESGEATDDEMVTRKAKVYRECRSRSGSDPQDINEQEESEANAIASPPNPSRR
AHSLTTAGSPNLSAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMV
SDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYSVPCNRSSSESTPLYTNLTIEENTSDLQ
PDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQ
LNDFLVNCQGEHCTYDEILSVIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKNDESQ
ENMKELQLPLSYYYIESSHNTYLTGHQLKGDSSVELYSQVLLQGCRSIELDCWDGDDGMP
IIYHGHTLTTKIPFKDVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKTVFGEK
LVAKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQASN
GGNVNPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCTDKLQFEYNEEIPKRIK
KADNSAYNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNSSGS
SRGKERKSRKSIFGNNPGRMSPGEATSFNKTSGKSSLEGVRQTWEESSSPLNPTTSLSAI
IRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLHG
IQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDP
AIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFRV
HFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFVSSRRM
EEISSGSTVPASLMFNTEERRCSQTHRVTVHGVPGPEPFAVFTISGGTKAKQLLQQILTS
DQDTKLIATDYFLMEEKYFISKEKNECRKPPFQRVIGPEEEIMQILSSWFPEEGYVGRIV
LKAQQESVEEKSVAQDDKEMILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQEVIQQT
LCKAKYSYSILSNPNPGDYVLLEEVVKDTPNKKSATPKSSQRVLLDQECVFQAQSKWKGA
GKFILKLKEQVQASREDKRRGISFASELKKLTKSTKQPRGLISPPQLSASESLQTKEKPA
SSLSSSDRMECRQ
NT seq 6882 nt   +upstreamnt  +downstreamnt
atgacttctgaagaaatggcagcttctgtcctcacccctatgactcagagaaaagcagaa
tctgcccaggcagtcgcagatgaaaggaacgagaaggtctctgacattagtattccaaag
gtccatggcatcaagcagagcaggcagattcccatctcacaatgggacaatctgaaagaa
gaatcttctggaagcagtttgcccaaggtactctcagtagcaagggagaaaatagtgagt
gatgagaacctcaatgaaaagtgctgggagaaaagcacagcagattctgtgaaaaacctt
aacacaaaccgcagctgtatattgggaaaccatcagcgtgtcctccctcagagccagttt
tatgaaacatgcaactctgtcatagaggaaggtctgtgtttggaaactggaattccttct
ccactggaaagagatgtgttccctggaattcaactggaaatagccaggtcacctctaggt
atgaatcctttagtaaaccatcctgggatcatagacaccaacagatctcattctgagagt
aacatggcagtatttcgtcttcattatgaggttgacagaaggatgtcagacacttttcat
actctatcagaaaatttaattttggatgattgtggaaattgcattccacttcctgttggg
gaggaaaagaaacattacatggcatatacttgtaaactgatggaattggcccaaacctgt
ggcaataagaatgggcagctgcagtgtgaacattgtgatcccttgagtgatgaatacctg
tgcttccaaggccagaaggtcaacgtggtttgtccaactgaaagcttttgcagggaggat
tttaaagaaaatccacctgcgaagacctttttgagccatcttgaggatttccctggtaat
tgtgaagatgtagaagatttttttaaaggcagaaaggagcgttctactttgctaattagg
agattttgtaagaatgacagggaagttaagaaatctgtatatactgggacaagagcaata
gtaagaacgctgccttctggccgcattgggctggttgcatggagttatgttgatcagaag
agacacggtttcttactcccttgtggaagagacatggcgcctccatcaaaagtggataca
aggcaaggcaggagccaatgtctgccagaaggccagtggtatttgatctacaatgcagtg
agaagaagagaagaaacagaagatatagttggatctcttctccatttcttcacaaaattg
tcagcctccaagacagtccatggaacgattcatgtttggccatgtgtaaagcagtgtgtc
cgagataccacatgtgagttccgtgccacctcccaaaggacttccctatctcagtacatc
accggttccctcctagaagcaaccacctctttaggagcaagaagttgccttcttagtact
tttggaggatccactggacgaatgatgctgaaagaacgccaaccaggaagctcaatggca
aattccagtgccctcccttcaagttcagctggcatcagcaaggaactgattgatctgcag
cccctcattcagttcccagaggaagtcgccagcatcctgacagagcaggagcagaatatt
taccgaaaggtcctgcctgttgactacctttgcttcttaactcgagacttgggtacccag
gaatgccagagatccctgccctgccttaaagcttccatctcagcatcaattctcacctct
caaagtggagagcacaatgcccttgaagacctcgtgatgagatttaatgaggtcagctcc
tgggtaacatggctgatcctcacagcaggatcaatggaggagaagcgggaagtcttctca
tatttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgctgtcatggag
ttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagttcatggaccagtct
gacattgagactatgcggagcctgaaggacgccatggctcagcatgagtcctccctggag
tacaggaaggtggtgacgcgggcactgcacatcccaggttgtaaggtggttcccttctgt
ggcgtgtttttgaaggagctctgtgaagtgcttgacggagcctctggcctcctaaagctt
tgcccacggtacaactcccaggaagaggctttagagtttgtagcagattacagtgggcaa
gataatttcttgcaacgagtgggacacaatggcttgaagaactcagagaaggagtccacc
gtcaacagcatcttccagatcatcaggagctgcagccgaagtctggagacagaagaggag
gacagcgccagcgaaggggacagctctaggaagaattccttgaaggataaaacccgatgg
cagtttataatcggagacttgttggattcagaaaatgacatctttgagcgctctaaagaa
tgtgaccctcacagatcagaagaggcacagaaggcctttgaccatgggacagagctcatc
ccatggtatgtgctgtccatccaagcggatgtgcaccagttcctgctgcagggggccacg
gtcatccactacgaccaggactcacacctctctgcccgctgcttccttcagctgcagcct
gacaatagcactttgacctggataaagccccctactgcctcgcctgccagtgcaaaagcc
aagtgtggagtgctaagtaacacagctgagcctggcaagttcccattattgggcaatact
gggttaagtggcctggtggagggagtcttggatctattttcagccaaggctgtgtacatg
ggacaccctggcattgatatacacactgtgtgtgttcagaacaaactaggtggcatgatc
ctgtcagagactggtgtgacactgctatatggccttcagaccacggacaatagattacta
cactttgtggcaccaaagcatacagctaaaatgctcttcagcggattattggaactcact
agagctgtgagaaagatgaggaggtttcctgaccaaagacagcagtggctgcggaaacag
tatgtcagcctctatcaggaggatggtcggtatgaaggcccaactttagctcatgctgtg
gagttgtttggtggcagacggtggagtacccggaatcccagccctgggacatctgcaaaa
aatgctgagaagcccaacatgcagagaaacaacaccctaggcataagtgccaccaagaaa
aagaagaaaatcctcatgaggggggagagtggagaggccacggacgatgagatggtgacc
cgaaaggctaaagtgtacagagagtgtcgaagccgaagcggttctgatcctcaggatatt
aacgaacaggaagaatcagaagcaaatgccattgctagccctcccaacccttccagaagg
gctcactctttgaccacggctgggtcccccaacttgtctgctggaacatcatctcccatc
aggccagtctcctcccctgtgctgtcttcttcaaacaagagtccatccagtgcctggagc
agcagtagctggcatgggaggatcaaaggaggaatgaaggggttccagagcttcatggtt
tcagacagcaacatgagttttgttgaattcgttgagctgttcaaatcattcagtgtaagg
agccgaaaggacctcaaggacctctttgacatctactctgtgccctgcaaccgttccagc
tctgagtccacccccctctacaccaacctgacaatcgaggaaaacaccagtgacctacaa
cctgatctagatttgttgaccagaaatgtctcggacttgggattgttcattaagagcaag
cagcagctttcagacaaccagaggcagatatctgatgctattgctgctgcaagtatcgtg
acaaatggcactggcattgagagcacgtccctgggcatatttggagttggcatacttcaa
ctcaatgacttcctggtcaactgccaaggtgaacactgcacatatgatgagatcctcagc
gtcatccagaaatttgaacctagcatcagtatgtgtcatcaaggcttaatgtcatttgaa
ggatttgcaaggtttctgatggacaaagacaattttgcctcaaaaaatgatgagtcccag
gagaacatgaaagaattacagctacccctctcctactattacattgaatcttcacacaac
acgtacctcacaggccatcagctcaaaggagactcctcagtagaactctacagccaggtc
ctcttgcaaggctgcaggagcatcgagctggactgctgggatggagacgatgggatgccc
attatttatcatggacacacactgaccaccaagatccccttcaaggatgtggtcgaagcc
atcgatcgcagtgccttcatcacctctgacctgcctatcatcatatcgattgagaaccat
tgttcattgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttggagaaaag
ctggtggcaaaattcttatttgagactgatttctcagatgatccaatgctcccttcaccc
gaccaacttaggaaaaaagtacttctgaaaaacaagaagctgaaggcccatcagacgcca
gtggatatcttaaagcagaaggctcatcagttagcatccatgcaggcacaggcttctaat
ggtgggaatgttaaccccccacctgccaataatgaggaggaggaagatgaagaggatgaa
tatgattatgactatgaatccctttctgacgacaacattctggaagacagacctgaaaat
aaatcatgtactgacaagcttcagtttgagtacaatgaagaaatccccaagaggataaag
aaagcagataactctgcttacaacaaagggaaggtgtatgacatggaactcggagaagaa
ttttatcttcctcaaaataaaaaggaaagcagacagattgcaccagagctttccgacctt
gtcatctattgccaagctgtgaaatttccaggcttgtcaactttaaattcatctggctct
agcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatcctggcagaatg
agcccaggggaggcgacatcatttaacaaaacatctggaaaaagttcccttgaaggagtt
cgacagacctgggaggaatcttcttcccctctcaatccaacaacatccctcagcgctatc
attaggacgcccaaatgctatcatatctcatcactgaatgaaaatgccgccaaacgtctg
tgtcgcaggtattctcagaaactgatccagcacactgcctgtcagctgctgaggacttac
ccagccgccacccgcatcgactcctccaaccccaacccactcatgttctggctccacggg
atccagcttgtggcgctcaactatcaaactgatgatctcccgttacatttaaacgctgca
atgtttgaggcaaatggtggctgtggctatgttttgaagcccccagtactgtgggacaag
aactgccccatgtatcagaaattttctccactggaaagagatctagacagcatggaccct
gccatctattccttaactattgtctcaggccaaaatgtgtgccctagtaacagcacagga
agcccctgcattgaagttgacgtactgggcatgcccctggacagctgccatttccgcacc
aagcccatccatcgaaatactctgaaccccatgtggaacgaacagttcctgttccgagtt
cactttgaagatctcgtatttcttcgttttgcagtggtggaaaacaacagttcagcagta
actgctcagagaattattccactcaaggctttaaaacgaggatatcgacatcttcagctg
cgaaatctccacaatgaagtcttagaaatctctagtttatttgtaagcagcagaagaatg
gaagaaatttcctctggcagtactgtgccagcctctttgatgtttaatacagaagagaga
agatgttctcagactcacagagtcacggtacatggggtcccagggccagagccctttgct
gttttcactataagtggaggcaccaaagcaaagcagctgctccagcagattctgacatct
gatcaagacaccaaactgattgccaccgactattttttgatggaagaaaagtatttcata
tctaaagaaaagaacgagtgcaggaaaccaccattccagagggtcattggtccagaagaa
gagatcatgcagattttaagcagctggtttccagaagaaggatatgtgggcagaattgtt
ttaaaagcacagcaggaatctgtagaagagaaaagtgttgctcaggatgacaaagagatg
atcttgagctcagaggaggaaagtttcttcgtacaagtgcatgacgtttctccagaacag
cctcgaacagtcatcaaagcaccccgtgtcagcactgcacaggaggtcattcagcagact
ttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccaggcgactacgtg
cttttggaagaggtggtaaaagacacacccaacaagaaatctgccaccccaaagtcctca
cagcgggtccttctggatcaggagtgcgtgtttcaagcccaaagcaagtggaaaggtgca
ggaaaattcatccttaagctcaaagagcaggtgcaggcatcccgtgaagataaaagaaga
ggcatctcttttgcgagtgaactcaagaagctcaccaagtcaacgaaacagccccgagga
ctcatatctcctccccagctttcagcctcagagagtctccaaaccaaggagaaacctgcg
agtagcttgtcctccagtgacaggatggaatgccgacagtga

DBGET integrated database retrieval system