KEGG   Dipodomys spectabilis (banner-tailed kangaroo rat): 122120491
Entry
122120491         CDS       T07891                                 
Symbol
Src
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
dsp  Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01521  EGFR tyrosine kinase inhibitor resistance
dsp01522  Endocrine resistance
dsp04012  ErbB signaling pathway
dsp04015  Rap1 signaling pathway
dsp04062  Chemokine signaling pathway
dsp04081  Hormone signaling
dsp04137  Mitophagy - animal
dsp04144  Endocytosis
dsp04360  Axon guidance
dsp04370  VEGF signaling pathway
dsp04510  Focal adhesion
dsp04520  Adherens junction
dsp04530  Tight junction
dsp04540  Gap junction
dsp04611  Platelet activation
dsp04613  Neutrophil extracellular trap formation
dsp04625  C-type lectin receptor signaling pathway
dsp04727  GABAergic synapse
dsp04750  Inflammatory mediator regulation of TRP channels
dsp04810  Regulation of actin cytoskeleton
dsp04912  GnRH signaling pathway
dsp04915  Estrogen signaling pathway
dsp04917  Prolactin signaling pathway
dsp04919  Thyroid hormone signaling pathway
dsp04921  Oxytocin signaling pathway
dsp04926  Relaxin signaling pathway
dsp05100  Bacterial invasion of epithelial cells
dsp05135  Yersinia infection
dsp05152  Tuberculosis
dsp05161  Hepatitis B
dsp05163  Human cytomegalovirus infection
dsp05167  Kaposi sarcoma-associated herpesvirus infection
dsp05168  Herpes simplex virus 1 infection
dsp05203  Viral carcinogenesis
dsp05205  Proteoglycans in cancer
dsp05207  Chemical carcinogenesis - receptor activation
dsp05208  Chemical carcinogenesis - reactive oxygen species
dsp05219  Bladder cancer
dsp05417  Lipid and atherosclerosis
dsp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:dsp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    122120491 (Src)
   04015 Rap1 signaling pathway
    122120491 (Src)
   04370 VEGF signaling pathway
    122120491 (Src)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    122120491 (Src)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    122120491 (Src)
   04137 Mitophagy - animal
    122120491 (Src)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122120491 (Src)
   04520 Adherens junction
    122120491 (Src)
   04530 Tight junction
    122120491 (Src)
   04540 Gap junction
    122120491 (Src)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122120491 (Src)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    122120491 (Src)
   04613 Neutrophil extracellular trap formation
    122120491 (Src)
   04625 C-type lectin receptor signaling pathway
    122120491 (Src)
   04062 Chemokine signaling pathway
    122120491 (Src)
  09152 Endocrine system
   04912 GnRH signaling pathway
    122120491 (Src)
   04915 Estrogen signaling pathway
    122120491 (Src)
   04917 Prolactin signaling pathway
    122120491 (Src)
   04921 Oxytocin signaling pathway
    122120491 (Src)
   04926 Relaxin signaling pathway
    122120491 (Src)
   04919 Thyroid hormone signaling pathway
    122120491 (Src)
  09156 Nervous system
   04727 GABAergic synapse
    122120491 (Src)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    122120491 (Src)
  09158 Development and regeneration
   04360 Axon guidance
    122120491 (Src)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    122120491 (Src)
   05207 Chemical carcinogenesis - receptor activation
    122120491 (Src)
   05208 Chemical carcinogenesis - reactive oxygen species
    122120491 (Src)
   05203 Viral carcinogenesis
    122120491 (Src)
  09162 Cancer: specific types
   05219 Bladder cancer
    122120491 (Src)
  09172 Infectious disease: viral
   05161 Hepatitis B
    122120491 (Src)
   05168 Herpes simplex virus 1 infection
    122120491 (Src)
   05163 Human cytomegalovirus infection
    122120491 (Src)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122120491 (Src)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    122120491 (Src)
   05152 Tuberculosis
    122120491 (Src)
   05100 Bacterial invasion of epithelial cells
    122120491 (Src)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122120491 (Src)
   05418 Fluid shear stress and atherosclerosis
    122120491 (Src)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    122120491 (Src)
   01522 Endocrine resistance
    122120491 (Src)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dsp01001]
    122120491 (Src)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dsp04131]
    122120491 (Src)
Enzymes [BR:dsp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     122120491 (Src)
Protein kinases [BR:dsp01001]
 Non-receptor tyrosine kinases
  SRC family
   122120491 (Src)
Membrane trafficking [BR:dsp04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    122120491 (Src)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    122120491 (Src)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    122120491 (Src)
  Macropinocytosis
   Kinases
    122120491 (Src)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 SH3_10 DUF7063 ABC1 Haspin_kinase SH3_3
Other DBs
NCBI-GeneID: 122120491
NCBI-ProteinID: XP_042550676
LinkDB
Position
Unknown
AA seq 533 aa
MGSNKSKPKEGGQRRRSLEPTEAPGAFPASQTPSKPASADGLRGPASAFAPTAATAEPKL
FGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWL
AHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNTENPRGTFLVRESETT
KGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG
TMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRL
PQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQ
GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYR
MPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1602 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagccgaaggaggggggccagcggcgccgcagcctggagccc
accgaggccccaggtgccttcccggcctcgcagacgcccagcaagcccgcctctgccgat
ggcctccgaggcccggcctctgcctttgcgcccactgctgccaccgctgagcccaagctg
tttgggggcttcaactcctcggacaccgtcacctccccgcagagggcagggccgctggcc
ggtggagtgaccaccttcgtggctctctatgactacgagtcacgaacagagactgacctg
tccttcaagaaaggggagcggctccagatcgtcaacaatacagagggagactggtggctg
gcccactcgctcagcacaggacagaccggctacatccccagcaactacgtggcgccctca
gactccatccaagctgaagagtggtacttcggcaagattaccagacgggagtcagagcgg
ttactgctgaacacagagaacccaagagggaccttcctggtgagagaaagtgagaccacg
aaaggtgcctactgcctctcggtgtctgacttcgacaacgccaagggcctcaatgtgaag
cattacaagatccgcaagctggacagcggcggcttctacatcacctcccgcacccagttc
aacagcctgcagcagctggtggcctactactccaagcatgccgacggcctgtgccaccgg
ctcaccaccgtgtgccccacatccaagccgcagacccagggcctggccaaggatgcctgg
gagatcccccgagagtccctgcggctggaggtcaagctgggccagggctgcttcggggag
gtgtggatggggacctggaatggcaccaccagggtagccatcaaaaccctcaagccgggc
accatgtctccagaggccttcctgcaggaggcgcaagtcatgaagaaactgaggcacgag
aagttggtgcagctgtatgctgtggtgtcagaggaacccatctacattgtcacggagtac
atgagcaaggggagtttgctggacttcctcaagggggaaacgggcaagtacctgcggctt
cctcagttggtggacatggctgctcagatcgcctcgggcatggcatacgtggagcggatg
aactacgtccaccgggacctccgcgcggccaacatcctcgtcggggagaacttggtgtgc
aaggtggcggactttgggctggcccgcctcattgaggacaatgaatacacggcccggcaa
ggtgccaagttccccatcaagtggacagcgcccgaagcagccctctacggccgcttcacc
atcaagtcggacgtgtggtccttcgggatcctcctgacggagctcaccaccaagggacgg
gtgccctaccctgggatggtgaaccgggaggtgctggaccaggtggagaggggctaccgc
atgccctgcccgcccgagtgccccgagtccctgcacgacctcatgtgccagtgctggcgg
aaggagccggaggagcggcccaccttcgagtacctacaggccttcctggaggactacttc
acgtccaccgagccgcagtaccagcccggggagaacctatag

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