Dipodomys spectabilis (banner-tailed kangaroo rat): 122121761
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Entry
122121761 CDS
T07891
Symbol
Cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp02010
ABC transporters
dsp04024
cAMP signaling pathway
dsp04152
AMPK signaling pathway
dsp04530
Tight junction
dsp04971
Gastric acid secretion
dsp04972
Pancreatic secretion
dsp04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
122121761 (Cftr)
09132 Signal transduction
04024 cAMP signaling pathway
122121761 (Cftr)
04152 AMPK signaling pathway
122121761 (Cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
122121761 (Cftr)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
122121761 (Cftr)
04972 Pancreatic secretion
122121761 (Cftr)
04976 Bile secretion
122121761 (Cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
dsp02000
]
122121761 (Cftr)
Enzymes [BR:
dsp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
122121761 (Cftr)
Transporters [BR:
dsp02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
122121761 (Cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
SMC_N
AAA_21
AAA_29
AAA_16
T2SSE
RsgA_GTPase
DUF87
DO-GTPase2
Zeta_toxin
nSTAND3
MeaB
MMR_HSR1
Intein_splicing
AAA_30
NTPase_1
AAA_23
Motif
Other DBs
NCBI-GeneID:
122121761
NCBI-ProteinID:
XP_042551829
LinkDB
All DBs
Position
Unknown
AA seq
1700 aa
AA seq
DB search
MDKDIMAWHLLSNNWVGTVNVSTHLRKHITAPQIYWKISQNKRLKDTRMAFLVQPPQDGR
TFLGNFGHAYTLQQVCFVVPLPDCFCAHQLLRSSCRQHEQGLPRGKGIDEGDGEKAEDVT
GTGLGSQKKGGGEGGGGGGSGKLEAAGGGSREIWCVGRVGEAAGAGSAPAGRQGSRSVGL
GPGRLEGGCTGTVPRLRAGPGPSEKARDKGNLKKYLDPKCEVIRYEVNIEISSFYFSWTS
PILKKGYRQRLELLDIYQISSADSADNLSEKLEREWDRELASKKNPKLIHALRRCFFWRF
TFYGILLYLGEVTKAVQPLLLGRIIASYDPDNKAERSIAIYLAIGLCLLFIVRTLLLHPA
IFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQLISLLSNNLNKFDEGLALTHFV
WIAPLQVTLLMGLLWDLLQASAFCGLAFLILLALAQAGLGRKMMKYRDQRAGKINERLVI
TSEMIENIHSVKAYCWEEAMEKMIENLRQTELKLTRKAAYVRYFNSSAFFFSGLFVVILS
VLPYAFIKGIILRKIFTTISFCIVLRMAVTRQFPGAVQTWYDSLGAINKIQDFLQKQEYK
TLEYNLTTTEVVMENVTAFWEEGFGELFEKAKLNNNNRKISNGDSKLFFSNFSLLGTPVL
KNINFKIEKGQLLAVAGSTGAGKTSLLMMILGELEPSEGKIKHSGRISFCSQFSWIMPGT
IKENIVFGVSYDEYRYRSVIKACQLEEDISKFAEKDNIVLGEGGITLSGGQRARISLARA
VYKDADLYLLDSPFGHLDVLTEKQIFESCVCKLMANKTRILVTSKMEHLKKADKILILHE
GSSYFYGTFSELQNLRPDFSSKLMGFDSFDQFSAERRNSILTETLRRFSLEGDVSASWNE
SRKQSFKQTGEFGEKRKNSILNSINSVRKFSVAQKPPLQINGIEEDSDESLARRLSLVPD
SEPGEGILPRSNMINAGPTFQGRRRQSVLNLMTHSPSQGPSIHRRTTASTRKMSLAPQAS
LTEMDIYSRRLSQESGVDISEEINEEDLKECFFDDVESIPAVTTWNTYLRYITIHKNLIF
VLIWCLVIFLVEVAASLVVLWLLKNIPPQDDRNSTKSANNSYAVIITNTSFYYIFYIYVG
VADSLFVLGIFRGLPLVHTLITVSKILHHKMLHSVLQAPMSTLNTLKTGGILNRFSKDIA
VLDDLLPLTVFDFIQLLLIVIGAVAVVSILQPYIFLASVPVIAAFVLLRAYFLRTSQQLK
QLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQM
RIEMIFVLFFIVVTFTSILTTGEGEGSIGIILTLAMNIMNTLQWAVNSSIDVDSLMRSVS
RIFKFIDMPTEEGNSAKSTKPSKDSQLSKVMIIENQLVNKDDIWPSGGLMTVKDLTAKYV
DGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTEGEIQIDGVSWDSITLQ
QWRKAFGVIPQKVFIFSGTFRKNLDPYEQWTDREIWKVADEVGLRSVIEQFPGKLDFVLV
DGGYVLSHGHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRRTLKQAFADCTVILC
EHRIEAMLECQQFLVIEENRVRQYDSIQKLLSEKSLFRQAISTSDRVKLFPHRNSSKHKS
RSQIAALKEETEEEVQETRL
NT seq
5103 nt
NT seq
+upstream
nt +downstream
nt
atggataaagatataatggcatggcatttgttgagtaacaactgggttgggactgtgaat
gtaagcacccatctgagaaaacacatcacggccccacagatttactggaagatcagtcaa
aacaaaaggttaaaagacacccgaatggccttccttgttcagccaccacaggatggcaga
acttttttgggtaactttggacatgcctatactctgcagcaggtgtgcttcgtggtcccc
ttacctgattgcttctgtgctcaccagttgctgcggtctagctgcaggcagcacgaacag
gggctcccaaggggcaaggggattgatgaaggagacggagagaaggctgaagacgtaaca
ggaaccgggttaggatctcagaagaaaggaggaggagaaggaggaggaggaggaggatca
gggaagctggaggcagctggtggtgggtcccgtgaaatctggtgcgtcgggagggtcggg
gaggctgccggggctgggtcagctccggccgggcgccaggggtcccggagcgtcggtctc
ggcccggggagacttgaaggcggctgcacggggactgtgccccgcctgcgggctggtccc
gggccttctgaaaaagccagagataaaggaaatctaaagaaatacctggaccctaagtgc
gaggtgattcgatatgaagtgaatattgaaataagttctttctattttagctggaccagc
ccaattttgaagaaaggctatagacagcgcctagaattgttggacatatatcagatctct
tctgctgattccgctgataatctgtctgaaaagttggaaagagaatgggatagagaattg
gcttctaagaaaaatcccaaacttattcatgcccttcgacgatgctttttctggagattt
acgttctatgggatcttactatatttaggggaagtcaccaaagcagtacagccactctta
ctgggaagaatcattgcttcctatgatccagataacaaggcagagcgatccattgccatt
tacctagccataggcttatgtctgctttttatcgtgaggacactgctcctacatccagcc
atttttggccttcaccatattggaatgcagatgaggatagctatgtttagtttaatttat
aagaagactttaaagctatcaagtcgtgttctagataaaataagtattggacaactcatt
agtcttctttccaacaacctgaacaaatttgacgaagggcttgctttgacacattttgtg
tggattgcacctttacaagtgactctcctgatggggctgctctgggacttgttacaggcc
tctgccttctgtggccttgcttttcttatactccttgctcttgcccaagctggattaggg
agaaaaatgatgaagtacagagatcagagagccggaaagatcaatgagagacttgtgatc
acctcagaaatgattgaaaatattcactccgttaaggcatattgctgggaggaagcaatg
gaaaaaatgattgaaaacctaagacaaacggaactaaagttgacccggaaggcagcctat
gtgagatactttaatagttcagccttcttcttctctggcttgtttgtggtgattttgtct
gtgcttccctatgcattcatcaaaggaatcatccttcgaaaaatatttacaaccatctcc
ttctgcattgttctgcgcatggcagtcacacggcaattcccaggggctgtacaaacatgg
tatgactctctaggagcaataaacaaaatacaggatttcttacaaaagcaagaatacaag
acattggaatataacctaacaaccacagaagtagtgatggagaatgtaacagccttctgg
gaagagggatttggggaattatttgagaaagcaaaactaaacaataataacagaaagatt
tccaatggtgacagtaagctcttcttcagtaacttttcccttcttggtactcctgtcctg
aaaaatatcaacttcaagatagagaaaggacagttactggcagttgctggatctactgga
gcaggcaagacatcactcctgatgatgattttgggagagttggagccttcagagggtaaa
ataaagcacagtggaagaatttcattctgttctcagttttcctggatcatgcctggtacc
atcaaagaaaacattgtttttggtgtttcctatgatgagtatagatatagaagtgtcatc
aaagcatgtcaactggaagaggatatctcaaagtttgcagagaaagacaacatagttctt
ggagaaggtggaatcacactgagtggaggtcaacgtgcaagaatttctttagcaagagca
gtatacaaagatgctgatttgtacctcttagactctccttttggacacctagatgttcta
actgaaaaacaaatatttgaaagctgtgtctgtaaattgatggctaacaaaactaggatt
ttggtcacttctaaaatggaacatttaaagaaagctgacaaaatattaattttacatgag
ggtagcagctatttttacgggacattttctgaactccaaaacctacggccggacttcagt
tcaaaactcatgggatttgattctttcgaccagtttagcgcggaaagaagaaattcaatc
ctcacggagaccttacgccgtttctccttagaaggagacgtttctgcctcctggaatgaa
tccagaaaacaatcttttaaacagactggagagtttggagaaaagagaaagaactctatc
ctcaattcaatcaactccgtaaggaaattttcagtggcacagaagcctcctttacagatc
aacggcatcgaggaggattctgatgagtccctagcaagaagactgtccctggttccagat
tctgagccgggagagggaattctgcctcgcagcaacatgatcaacgcgggccccacgttt
cagggtcggaggagacagtctgttctgaacttaatgacacattcacctagccagggcccg
agcattcatcgcaggaccacagcctccaccagaaaaatgtctttggctcctcaggcaagc
ttaacggagatggatatttattccagacgcttatctcaagagagtggtgtagacatcagt
gaagaaattaatgaagaagatttaaaggagtgcttttttgatgatgtagagagcatacca
gcagttaccacatggaatacataccttcgatatatcactatccacaagaacttgattttt
gtgctaatttggtgcttagttatttttctggttgaggtagctgcttctttggttgtgttg
tggttacttaaaaacatccctcctcaagatgatagaaacagcaccaaaagtgcaaacaac
agctatgctgtgattatcaccaacaccagcttctattacattttttacatttatgtggga
gtggccgacagtttgtttgttctggggatcttcagaggtttgccactggtacacacactg
atcacagtgtcaaaaattttacatcacaaaatgttacattctgttcttcaagcacccatg
tctaccctcaacacactgaaaacaggtgggattctcaatagattctccaaagatatagca
gttttggatgatcttctgcctcttaccgtatttgacttcattcagttgctattaattgtg
attggggcggtggccgtagtctccattttacaaccctacatcttcctagcatctgtgcct
gtgatagcggcctttgttctactgagagcttactttctccgcacctcccagcaactcaaa
caactggagtctgaaggcaggagcccaattttcactcatcttgtgacaagcttaaaagga
ttatggacacttcgtgccttcggacgtcagccttattttgaaacattgttccataaagct
ctgaatttacacaccgccaattggttcttgtatctgtcaacactgcgctggttccagatg
agaatagaaatgatttttgtcctcttcttcattgttgttactttcacttccattttaacc
acaggtgaaggtgaaggatcaattggcattattctaactttagctatgaatatcatgaac
acattgcaatgggctgtaaactccagcattgatgtggatagtttgatgcgctctgtgagc
cgaatctttaagtttattgacatgccaacagaagaaggtaattctgccaaatcaacaaaa
ccatccaaagacagtcagctctcaaaagttatgattatcgagaatcagctggtgaacaaa
gatgacatctggccttcaggaggcctaatgactgtcaaagacctcacagcaaaatacgtt
gacggtgggaacgccatattagaaaacatttccttctcaatcagtcctggccagagggtg
ggcctcttaggaagaactggatcagggaagagcaccttgttatcagcttttctgaggctt
ctgaacactgaaggagaaatccagattgatggtgtgtcttgggattcaataactttgcag
cagtggcgaaaagccttcggagtgatacctcagaaagtatttatcttttctggaacattt
agaaaaaacttggatccatatgaacagtggactgaccgagaaatatggaaagttgcagat
gaggttggactcagatctgtgatagaacagtttcctgggaagcttgactttgtccttgtg
gatgggggttatgtgctaagtcatggtcacaagcagttgatgtgcttggccagatctgtt
ctcagcaaagcaaagattttactgcttgatgaacccagcgctcatttggatcccataacg
tatcaagtaattcgaagaaccctaaagcaagcatttgctgattgcacagtgatcctgtgt
gaacacaggatagaagcaatgttggaatgtcaacaatttttggtcatagaagagaacaga
gtgaggcagtatgactccatccagaagcttctgagtgagaagagcctgttcaggcaggcc
atcagcacctcagacagggtcaagctcttcccgcaccgcaactccagcaagcacaagtct
cgatcccaaattgctgctctgaaggaggagacagaggaagaggtccaagaaacccgactc
tag
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integrated database retrieval system
