Dipodomys spectabilis (banner-tailed kangaroo rat): 122122519
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Entry
122122519 CDS
T07891
Symbol
Srd5a2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00140
Steroid hormone biosynthesis
dsp01100
Metabolic pathways
dsp05215
Prostate cancer
Module
dsp_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
122122519 (Srd5a2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
122122519 (Srd5a2)
Enzymes [BR:
dsp01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
122122519 (Srd5a2)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
122122519
NCBI-ProteinID:
XP_042552695
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All DBs
Position
Unknown
AA seq
254 aa
AA seq
DB search
MLGGCQQSPVVAGSAFLAVFGAMVLYFAEPSGYGKHSNRLAPGGTCLPACVAWFLQELPS
FAVPAAILARQPGSLFGQPETVLLALFCAHYFHRTFIYSLLTRGRPFPAVLVLKGFLFCT
INGFLQTYYLSYCVEYPEEWYTDMRFSLGVFLFFLGMGINIHSDYTLHQLRKPGEITYRI
PQGGLFTYVSGANFLGEIIEWMGYALATWSLPALAFAFFSLCFLGMRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgctcggtgggtgccagcagagcccggtggttgccgggagcgccttcctggccgtcttt
ggggctatggttctgtacttcgcggagccctccggctatgggaagcacagcaacaggctg
gcgcccggcgggacctgcctgcccgcctgtgtcgcctggttcctgcaggaactgccctcc
ttcgccgtgcccgccgccattctcgcccggcagcctggctctcttttcggacagcccgag
acggtgctcctggccctcttctgcgcacattacttccacaggacatttatttactccttg
ctcactagagggagaccttttccagctgttctggttctcaaaggatttctcttctgtact
ataaatggattccttcaaacctactatctgagttactgtgtagaatatcctgaagagtgg
tacacagacatgcggtttagcttgggtgtcttcctattttttttgggaatgggaatcaat
attcacagcgactacacattgcatcagctcaggaagcctggagaaatcacttacaggatt
ccacaaggtggcttgtttacctatgtttctggagccaatttccttggtgagatcattgaa
tggatgggctacgccttagccacttggtcccttcctgctcttgcatttgcatttttctca
ctttgtttccttgggatgcgagcttttcaccatcacaggttctacctcaagatgtttgag
gactaccctaaatctcggaaagcccttattccatttatcttttga
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