Dipodomys spectabilis (banner-tailed kangaroo rat): 122122869
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Entry
122122869 CDS
T07891
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp00310
Lysine degradation
dsp01100
Metabolic pathways
dsp05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
122122869 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
122122869 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dsp03036
]
122122869 (Dot1l)
Enzymes [BR:
dsp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
122122869 (Dot1l)
Chromosome and associated proteins [BR:
dsp03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
122122869 (Dot1l)
HMT complexes
Dot1-containing complex
122122869 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
122122869
NCBI-ProteinID:
XP_042553233
LinkDB
All DBs
Position
Unknown
AA seq
1740 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAGPAEATVDSGAEEEKAGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKNQTALDLLNTQTTSQTTSPSPQDAYRSPNSPCYQLPPSAQWHSPTPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLLGHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLERDNLELRSQSLQLL
RARCEELKLDWATLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SYVPPDDTLSMHLPGKGTLGRELEADAGRLHLELDCAKFSLPNFSSMSPELSMNGHTASY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPNHSGRPRLEKLSGLALPDYTRLSPAKIV
LRRHLGQDHVAAGKAATSEPHPRAEHTKENNLPYQSPGLSNSMKLSPQDPRPPSPGSLPT
AGEKSNEKGVKERSYGSQGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERVRST
PSPVPQPRDSSSTLEKQIGANAHVAGGSAAGSRSLTLAPTGFYTGSVAISGALASSPAQL
ASGAESAAFDESSSSGSLFTMVGSRSTTPQHPPLLTQPRNSGPTSPIPQLSASPRFSGVT
QGLLPDAGKGDLPSDSGFSDPENEAKRRIVFTISAGTGSAKQSPSTKHSPLAANTRGDCG
QSHGQDSRKRGRRKRASAGTPSLSAGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQ
PLEITAISSPENSLKSSPVPYHDHDQPPVLKKERPLSQSNGAHYSPLTSDEEPGSEDEPS
STRIERKIATISLESKSPPKTLDNGGSLVGRKLAPASEPINSSKWKSTFSPISDIGLAKS
TDSPLQASSALSQNSLFSFRPALEEASAAEAKLTAHPRKSFSSTLLGADGLSPGANPPNG
LAFSGGLAADLSLHGFNDGASLSHKVPEAASLSTPLSFPSQRGKEGTSEANPFLSKRQLE
GLGGLKGESSAGKEVGELGLPLCGPTDKTALPHSSRANKGRDRDLDFKSGHNLFISAAAV
PPSGLLGGSGLPTVASSSGSTAPTTQTHRPFLSTFTPGPQFTLGPMSLQANLSSVAGSSV
LQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGTVGGIFSHTVPSASAHPFGV
SVSSGAVCSSAKLGLSPLQAVASTSASSFQAAASVETRPPPPPLLPPQHLGRSPAGPPVL
HAPPPPNVTLPPPPARLASNSEPVLLQNLASLPSNKTFLAPSSAASLQPANATLSVKLAS
LPHKVSHPSFTVHHQPLPRLALAQTAPAVPQASSVGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5223 nt
NT seq
+upstream
nt +downstream
nt
atgggggaaaagctggagctgagactcaagtcgcccgtgggggccgagcccgccgtctac
ccctggccgctgccggtctacgacaaacatcatgatgctgctcatgaaatcattgagacc
atacgatgggtctgtgaggaaattcccgacctcaagctggctatggaaaactatgtccta
attgactatgataccaaaagctttgaaagtatgcagcggctatgtgacaagtacaaccgg
gctatcgacagcatccaccagctgtggaagggcactactcagcccatgaagctaaataca
cggccatccaatgggctcctccggcacatactgcagcaggtctacaaccactcagtgact
gaccctgaaaaacttaacaattatgaacccttctccccggaagtatatggggagacctcc
tttgacctggtggcccagatgattgatgaaatcaagatgaccgaggatgatctgtttgtg
gacctgggtagcggtgtgggccaggttgtcctccaggttgctgcagccaccaactgcaaa
catcactatggagtagagaaagctgacatcccagccaagtacgcggagaccatggacaga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggcgatttcctctcggaagagtggagagagcgaattgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcaaaaccctttgcacctctgaacttcagaataaac
agcagaaacttgagtgacattggtaccatcatgcgtgtggtagagctgtcgcccctgaag
ggctcggtgtcatggacggggaagccagtctcctactatttacataccattgaccgcacc
atacttgaaaactatttttctagtctgaaaaacccaaaactcagggaggaacaagaggca
gctcggcgccgacagcagcgagagaacaagagtaatgccaccacccctaccaaagtccca
gagagcaaagcggctggacccgctgaagccaccgtggattctggtgctgaggaagaaaag
gctggggtggccactgtcaaaaagccatctccctccaaagctcggaagaagaagttgaac
aagaaagggaggaaaatggctggtcgaaagcgtggacgtcccaagaaaatgagcactgca
aaccctgaacgtaagcccaagaagaaccaaactgcactggatctcctgaacacccagacc
acatcccagaccacatccccctctccccaagatgcttacaggtcacccaacagcccatgc
taccagctacctccaagtgcacagtggcattctcccaccccactgctggtggcacctacc
ccgcctgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctggcc
tacacgaagacgccccagtacaaggccaacctgcaacagctgctggaccaggagaaggag
aagaacacacagttgctgggcacagcacagcagcttttgggccactgccaggcccagaaa
gaagagatccggagactcttccagcagaaactggatgagctgggagtgaaggcgctgacc
tacaatgatctaatccaggctcagaaggagatctctgctcacaaccagcagctgcgggag
cagtcagagcagctagagagagacaaccttgaactccggagccagagtctgcagctgctc
agggcccggtgtgaggagttaaagttggactgggccacactgtccctggagaaccttcgg
aaagagaaacaggccctgcggagccagatctctgagaagcagcggcattgcctagagctg
cagatcagcattgtggagttggagaagagccagcggcagcaggagctcctgcagctgaag
tcctatgtgccacctgatgacaccctgtccatgcatctgcctgggaagggcaccctgggc
cgtgagctagaagctgatgctggcaggctgcaccttgagctggactgtgccaagttttcc
ctgcctaacttcagtagcatgagcccagagctctctatgaatggtcacactgccagttat
gagctctgcagtgctctgagccgaccctcatccaagcagaacaccccccagtatctggct
tctcccttggaccaggaggtcgtgccctgtacccccaatcacagtggtcggccacggcta
gagaagctatctggtctggccttgcctgactatactcggctctcccctgccaagattgta
ctaaggaggcacctgggtcaggatcatgttgcagctggcaaggcagctaccagtgagcca
cacccacgagctgagcacaccaaggaaaacaacctaccctaccagagcccaggcttgtca
aacagcatgaagctgagcccccaggacccacgacctccctcccctgggtcattgcccaca
gcaggagaaaagagcaacgagaagggtgtgaaggaacgctcctatggcagccagggggag
accatcactagcctgcccatcagcatcccactcagcacggtgcagcccaacaagctcccc
gtcagcatccccctggccagtgtggtgctgcccagtcgcgccgaaagggtgaggagtacc
ccaagtcctgtgccgcagcctcgagactcctcgtccacacttgagaagcagattggtgct
aatgcccatgttgctgggggcagtgctgcagggagcaggagcctcactctggcacccaca
ggcttctacactggctcggtggccatcagtggggccctggctagcagcccagcacaactg
gcctctggagctgagtcagctgcctttgacgagtcctccagttcggggagcctcttcacc
atggtggggtcccgcagtacaacaccacaacaccctcctctgctgacacagcctcggaac
tctggccccacctctcctatcccccagctctctgccagccccaggttcagtggggttact
cagggcctgctgcctgatgctggcaagggagacctgccttctgattctggcttctcggac
ccggagaatgaggcaaagaggagaattgtgttcactatctcagctggcacaggcagcgcc
aagcagtcaccttcaaccaagcacagccccctggcggcgaatacccgtggggactgtggg
cagagccatgggcaggacagccgaaaacgtggcagaaggaagcgtgcatcagctggaacc
cccagcctgagtgcaggcgtgtcccccaagcgcagggccctccctactgttgctggcctc
ttcacacagtcctcagggtcccccctcaacctcaactccatggtcagcaacatcaaccag
cccttggagattacagccatctcgtcccctgagaactctctgaagagctcccctgtcccc
taccacgaccatgaccagccccctgtgctcaaaaaggaacgacctctgagccagtccaat
ggggcccactattccccactgacctcagatgaggagccaggctctgaggatgagcccagc
agcacccgaattgagagaaaaattgcaacaatctccttagaaagcaagtctcccccgaag
accttggataatggtggcagcttggtggggaggaaactggcacctgcaagtgagcctatc
aacagtagcaagtggaaatccaccttttcacccatctccgacatcggcctggccaagtcc
acagacagcccactgcaagctagctctgccctgagccagaactcattgttttcgttccgg
ccagccctggaagaagcctcggcggctgaggccaagctcactgcacatccaaggaaaagc
ttttccagcaccctattgggtgctgacggactcagtccaggtgccaacccccccaatggc
ctggccttcagtgggggcctggctgcagacctcagtttacacggcttcaatgacggtgct
tccctttcccacaaggtccctgaggcagccagcctgagcaccccacttagctttccttca
cagcggggcaaggagggcacctcggaagccaatcccttcctcagcaagcggcagctggaa
ggcctgggtggcctgaagggtgagagcagtgctggcaaggaggtgggagagctgggcctg
cccctgtgcgggcccacggacaaaacagctctaccacacagcagcagggctaacaagggc
cgggaccgtgaccttgacttcaagagtggccacaaccttttcatctctgctgcggcggtg
cctcccagtggccttcttggtggctctggcctccccacagtggcatcttcttcaggcagc
acagcccccaccactcagacacaccgccctttcctgagcaccttcacgcccgggccgcag
ttcaccctgggccctatgtccctgcaggccaatctcagctcagtggccggctcatctgtg
ctgcagtccttgttcagttctgtgccggccgctgcaggcctggtacatgtgtcatctgct
gcaaccagactgaccaactcccacgccatgggcagcttctcctccggggtggctggtgga
actgtcggaggtatctttagccacacggtgccctccgcctctgctcatccatttggagtc
agtgtcagcagtggggctgtgtgtagcagcgccaagctgggcctgagcccgctgcaggca
gtggccagcacctcggcctcttcctttcaggccgcggcctccgtggagactcggccgccc
cctccgcccctgcttcctcctcagcacctgggccggtcccctgcggggccacctgtcctc
catgccccccctccacctaacgtcaccttgcctcctccccctgcgcggctggcctctaac
tctgaacccgtgctcctgcagaaccttgcttccctcccatctaacaaaactttcttagcc
ccctcctctgccgcctctctgcagcctgctaacgcaactctgtctgtcaagctcgcctcc
ctcccgcacaaggtctcccatccctcattcacggtgcaccaccagcctctgccccggctg
gccctggcacagacagcacccgccgtcccgcaggccagctctgtgggtccatctgctgta
tgggtttcccttggcatgccgcctccctatgccgcgcacctttcgggggttaagccccga
taa
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integrated database retrieval system
