Dipodomys spectabilis (banner-tailed kangaroo rat): 122123999
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Entry
122123999 CDS
T07891
Symbol
Igf1r
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
dsp
Dipodomys spectabilis (banner-tailed kangaroo rat)
Pathway
dsp01521
EGFR tyrosine kinase inhibitor resistance
dsp01522
Endocrine resistance
dsp04010
MAPK signaling pathway
dsp04014
Ras signaling pathway
dsp04015
Rap1 signaling pathway
dsp04066
HIF-1 signaling pathway
dsp04068
FoxO signaling pathway
dsp04081
Hormone signaling
dsp04114
Oocyte meiosis
dsp04140
Autophagy - animal
dsp04144
Endocytosis
dsp04150
mTOR signaling pathway
dsp04151
PI3K-Akt signaling pathway
dsp04152
AMPK signaling pathway
dsp04211
Longevity regulating pathway
dsp04213
Longevity regulating pathway - multiple species
dsp04510
Focal adhesion
dsp04520
Adherens junction
dsp04550
Signaling pathways regulating pluripotency of stem cells
dsp04730
Long-term depression
dsp04913
Ovarian steroidogenesis
dsp04914
Progesterone-mediated oocyte maturation
dsp05200
Pathways in cancer
dsp05202
Transcriptional misregulation in cancer
dsp05205
Proteoglycans in cancer
dsp05214
Glioma
dsp05215
Prostate cancer
dsp05218
Melanoma
dsp05224
Breast cancer
dsp05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
dsp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122123999 (Igf1r)
04014 Ras signaling pathway
122123999 (Igf1r)
04015 Rap1 signaling pathway
122123999 (Igf1r)
04066 HIF-1 signaling pathway
122123999 (Igf1r)
04068 FoxO signaling pathway
122123999 (Igf1r)
04151 PI3K-Akt signaling pathway
122123999 (Igf1r)
04152 AMPK signaling pathway
122123999 (Igf1r)
04150 mTOR signaling pathway
122123999 (Igf1r)
09133 Signaling molecules and interaction
04081 Hormone signaling
122123999 (Igf1r)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122123999 (Igf1r)
04140 Autophagy - animal
122123999 (Igf1r)
09143 Cell growth and death
04114 Oocyte meiosis
122123999 (Igf1r)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122123999 (Igf1r)
04520 Adherens junction
122123999 (Igf1r)
04550 Signaling pathways regulating pluripotency of stem cells
122123999 (Igf1r)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
122123999 (Igf1r)
04914 Progesterone-mediated oocyte maturation
122123999 (Igf1r)
09156 Nervous system
04730 Long-term depression
122123999 (Igf1r)
09149 Aging
04211 Longevity regulating pathway
122123999 (Igf1r)
04213 Longevity regulating pathway - multiple species
122123999 (Igf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122123999 (Igf1r)
05202 Transcriptional misregulation in cancer
122123999 (Igf1r)
05205 Proteoglycans in cancer
122123999 (Igf1r)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
122123999 (Igf1r)
05214 Glioma
122123999 (Igf1r)
05218 Melanoma
122123999 (Igf1r)
05215 Prostate cancer
122123999 (Igf1r)
05224 Breast cancer
122123999 (Igf1r)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122123999 (Igf1r)
01522 Endocrine resistance
122123999 (Igf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dsp01001
]
122123999 (Igf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
dsp04090
]
122123999 (Igf1r)
Enzymes [BR:
dsp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122123999 (Igf1r)
Protein kinases [BR:
dsp01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
122123999 (Igf1r)
CD molecules [BR:
dsp04090
]
Proteins
122123999 (Igf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
122123999
NCBI-ProteinID:
XP_042554512
LinkDB
All DBs
Position
Unknown
AA seq
1369 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLCLSAALSLWPTSGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKSPKECGD
LCPGTMEEKPVCEKTTINNEYNYRCWTTNHCQKMCPSACGKRACTEDNECCHAECLGSCT
APDNATACVACRHYFHRGECVPDCPPDTYKFEGWRCVDRDACANIPSAESGDSEGFVIHD
GACMQECPSGFIRNGSQSMYCIPCEGPCPKVCGEEEKKTKTIDSVTSAQMLQGCTIFRGN
LLINIRRGNNIASELETFMGLIEVVTGYVKIRHSHALVSLSFLKNLRHILGEEQLEGNYS
FYVLDNQNLQQLWDWDHRNLTIKSGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINT
RNNGERASCESDVLHFTSTTTWKNHIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYD
GQDACGSNSWNMVDVDLPNNKDKEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKS
EILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYR
HNYCSKDKIPIRKYADGTIDVEEVTENPNTEVCGGEKGPCCTCPKTEAEKQAEKEEAEYR
KVFENFLHNSIFVPRPERKRRDIMQVANTTMSSRSRNATVVDVYNITDPEEVETEYPFFE
SRVDNKERTVISNLQPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGARLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVPAKTTYENFMHLIIALPVAIVLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYIPDEWEVAREKITMNRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPETEQKNVVLEPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAA
RNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSF
GVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPS
FLEIIGSIKDEMEPGFREVSFYYSEENKPPESEELDLEPENMESVPLDPSASSSSLPLPD
RHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRANERPLPLPQSSTC
NT seq
4110 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtgtctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtggaccaggcatcgacatccgc
aatgactaccagcagctgaggcgcctggagaactgcacagtgatcgagggctacctccac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcaccgtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctcttc
cccaacctcacggtcatccgtggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggacattgggctgtacaacctgaggaacattactcggggggct
atcagaatcgagaagaatgctgacctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtggggaacaagtccccgaaggaatgtggggac
ctgtgtcccgggaccatggaggagaagccggtgtgtgagaagaccaccatcaacaacgag
tacaactaccgctgctggaccacaaatcactgccagaaaatgtgccccagcgcgtgcggg
aagcgcgcgtgcacggaggacaacgagtgctgccacgccgagtgcctgggcagctgcacg
gcgcccgacaacgccacggcgtgcgtggcctgccgccactacttccaccgcggcgagtgc
gtgcccgactgcccgcccgacacctacaagttcgagggctggcgctgcgtggaccgcgac
gcctgcgccaacatccccagcgccgagagcggcgactcggagggcttcgtcatccacgac
ggcgcctgcatgcaggagtgcccgtcgggcttcatccgcaacggctcccagagcatgtac
tgtatcccctgcgaaggtccttgccccaaggtttgtggagaggaagaaaagaagacaaaa
actatcgactccgttacttctgctcagatgctccaaggatgcactatcttccggggaaat
ttgctcattaatatccgacgaggcaataacattgcttcggagctggagaccttcatgggg
ctcattgaggtggtgacgggttacgtgaagatccgccattcgcacgccctggtctccttg
tccttcctcaaaaaccttcgccatattctaggagaggagcagctggaagggaactactcc
ttctacgtcttggataaccagaaccttcagcagctgtgggactgggaccaccgcaacctc
accatcaaatcggggaagatgtactttgcattcaaccccaagctgtgtgtttccgaaatt
taccgcatggaggaagtgacggggacaaaaggacgccagagcaaaggggacataaacact
aggaacaatggggaaagagcctcctgtgaaagtgacgtcctgcattttacctctaccacc
acgtggaagaaccacatcatcatcacgtggcaccggtaccggcccccggactacagggac
ctcatcagcttcaccgtgtactacaaggaggcaccctttaaaaatgtcacagaatatgat
ggacaggatgcctgtggctccaacagctggaacatggtggacgtggacctccctaacaat
aaagacaaggagcccggcattctcctgcaggggctgaagccctggacacagtatgccgtc
tacgtcaaggccgtgaccctcaccatggtagagaatgaccacatccgtggggccaagagt
gaaatcttatacattcgcaccaatgcttcagttccttccattccactggatgtcctctcg
gcttcgaactcctcctctcagctgatagtaaagtggaatccaccatccctgcccaatggc
aacctgagttactacatcgtgaggtggcagcggcagcctcaggacggctacctgtaccgg
cacaactactgctccaaagacaaaatccccattaggaaatatgccgatggcaccatcgac
gtggaggaggtgacggagaatcccaacacagaggtgtgtggcggggagaaaggaccctgc
tgcacttgccccaaaacggaagctgagaagcaagctgagaaggaggaggccgagtaccgc
aaagtctttgagaatttcctgcacaactcaatctttgtgcccagacctgaaaggaagcgg
agagacatcatgcaggtggccaacaccaccatgtccagccggagcaggaatgccacagtg
gtggacgtctacaatatcacagacccagaagaggtggagacagaataccctttctttgag
agcagagtggataacaaagagagaactgtcatttcgaacctccagcctttcactttgtac
cgcatcgatattcacagctgtaaccacgaggctgagaagttaggttgcagcgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgacattcctggaccggtcacc
tgggaaccaaggccagagaactccatctttttaaagtggccagaacctgagaacccaaat
ggactcattctgatgtatgagatcaaatacggctcccaggtggaggaccagcgggaatgt
gtgtccagacaggaatacaggaagtatggaggggccaggcttaaccggctaaacccaggg
aactacaccgcccgaattcaggctacctctctctctggaaatgggtcgtggacagatcct
gtgttcttctatgtcccagccaaaaccacctatgaaaatttcatgcacctgatcattgct
ctgcccgtggccatcgtcctgatcgtggggggtctggtgatcatgctgtacgtcttccac
agaaagaggaataacagtaggctgggcaacggagtgctctatgcctctgtgaacccagag
tacttcagtgcagcagatgtgtacattcctgatgagtgggaggtagcccgggagaagatc
accatgaaccgggagcttgggcaagggtcctttgggatggtctatgaaggcgtggctaag
ggtgtggttaaagatgagcctgaaaccagagtggccattaagacggtgaatgaggcagcc
agcatgcgggaaaggattgagtttctcaatgaggcctcagtgatgaaggagttcaattgt
caccacgtggtgcggttgctgggcgtggtgtcccagggccagccaacgctggtcatcatg
gaactgatgacccggggcgatctcaaaagttacctcaggtctctgaggccggaaacagag
cagaagaacgtagtcctggaacctcccagtctgagcaagatgatccagatggctggcgag
attgccgacggcatggcatacctcaacgccaacaagtttgtccacagagacctcgcggcc
cgcaattgcatggtggccgaggatttcacagtcaaaatcggagattttggtatgactcga
gatatctacgagacagactactaccggaaaggaggcaagggcctgctgcccgtgcgctgg
atgtccccggagtcacttaaggacggcgtcttcaccacccattcggatgtctggtccttc
ggggtggtcctctgggagattgccacactggctgagcagccgtaccaaggcttgtccaac
gagcaagtccttcgcttcgtcatggaaggcgggcttctagacaagccagacaactgccct
gacatgctgttcgagctgatgcgaatgtgctggcagtacaaccccaagatgcggccctcc
ttcctggagatcatcggcagcatcaaggacgagatggagccgggcttccgcgaggtctcc
ttctactacagcgaggagaacaagccccccgaatccgaggagctggacctggagcccgag
aacatggagagcgtgcccctggacccctcggcctcctcctcctccctgcctctgcccgac
agacactcaggacacaaggccgagaatggcccgggccctggagtgctggttctgcgagcc
agcttcgacgagagacagccgtatgcgcacatgaacggcggccgcgccaacgagcgcccg
ctgccgctgccccagtcgtccacctgctga
DBGET
integrated database retrieval system
