Drosophila serrata: 110177000 Help Entry 110177000         CDS       T06108                                  Name (RefSeq) protein purity of essence   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism dsr  Drosophila serrata Brite KEGG Orthology (KO) [BR:dsr00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dsr04121]     110177000 Enzymes [BR:dsr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      110177000 Ubiquitin system [BR:dsr04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     110177000 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Htt_N-HEAT_1 Motif Other DBs NCBI-GeneID:  110177000 NCBI-ProteinID:  XP_020799168 LinkDB All DBs Position Unknown AA seq 5336 aa AA seqDB search MSAHSGGTDWNFVVKALLQNRTGALNKNEVVSLLRAITRCEHDFFDEESSYTQFYTAFAA LAADKLMQIKTICQTQICQLHDATAVLIRFIIYRLPRVSVYETKWLLVALKMLCEGRENV SMSSVMFDYNAVATVLKSCKHPESTTSKSILPSSSSSSSSGTGGNADKESPKLEIKRSRS DLSSVILQQLLAPLEPGKMTWVPLSEEVTDCTDQLLAANVEYFQEQNGVDTLLDVCVGLP ILNRYRSKYLETINGGKPLYLPLTQVEATTVKSTMNHMLTDLNILSQAHALIVLQPLTPS RIERFSSCGIAALYNAVLVSITASVLSMCQTSSSSQKQSAASTSQGSGGGGGGSSTGQSN KDHDDFEEQACSIVSKALEIYSAIGDLFKSSARMHVYQNHLCYGSWLLISGIQGAMGASG SGGDTSSKSATKTAKSGNEATAPSTPIARVNLFKVQQGFGELNAAIANHSIKLLSELIED LKIESACGPNPESTELPAPAQFDILQSYSSLGRIVRVLNTATLHQLFTFLATVAYRKACT QRRASAKDRAECEPISYSDSTTYFNDSLSCSDNSEEDDSESYLGHWFKETLSPETHDDNA NTSAQERSGGEQKSSLVPKLDEPHEYLDLAADIFCFLDEFLANKHAYMQRYVKAGVSDQQ MLLMANIIKDFDRDVMRNDSEQGSGNTPAASAGAGSSAAATTKWQTAMIRFSGSAGRYIH NLISTSLLSEQLQSNLLQHLAISPWSTDTSTWPLQVYPSTLSVLVQILLLKPTQEKEAAC LSVWHRLINTLVEGVCNWSAASYTDYEDLNIEHAQLLLFLFHSLNLMQKKSILLLTAGGV IRCAEVCRGISGDRPVKNSQMMLLSRLLLFLEYLMKHLYNAPPELLDQVRWNLFSVSSMP ETQKITDLLNSRTKLNLYFRQDIEERFRKSAGEYGSAIRPTFYTLVMADPEKPYWAQEFK LDGLAWNFILCTPDKLKYPLLVDALTDILSIVDMSAFTKDKEAKDANMQSLCAMQYCFSI AWKLILGLPPSTSHVESLKVEPAPNLHSLIWSIRCPLATSHYLVVNSLIKQGMYTQYSET LWREVGDIAGDLKYSLKQTILGVEAFNTQMNGNGTPRLSDLILFDSLVAHMQAVAWASKE GLKLPRRETDEISSDQSSSGAAASSNDADVYSSNESIDDEKAQQEEESELPSDLQKHNQL VNELMLKLMNSYRLLSVIVRGQMLKQLSSSTPEQALNLIVPIVSDKPAIMLELHAAFLKL LPNEDKQLIANEWPKCLMVNDSAFDGKQFPVEPYTLNVIDAHIMELTRGANYSTLHTLKH CLKSILHLFELLLPHCSHSNNEMESQLKGLLIASMLDMRTDYLQGQSEQCLREILSGLTL EAQKLLLYEHMIGYCYRMLKDFAADLRQTAPPLDQERAMFNESMLFAVLKTMIKMVDKPT GMQAMRQFFKDQKSGSLTTLLLSFTGTSLPVSYARKMLQFVERLFQQSSQADSQFLHDDL VECFSELATVDVARLKLWLAHIIYGPNVSTEVSTSEAMDTTCRLLTSIMQPSSSSSSNAQ TPTNMATVSAMPSISDQLDAMEIDYDCGTAAGGGGESGTGAGGAGGANTSQILSLWQAAQ PNPSEESSQACCEHSGTERNGALLLSFVKSLVKDQSKAAQIAPPLFQALLQLGQTLISPP QDACDFADVLQIMITLADAIPARGHAALFNTTVLWLELEKQQLPDKQLRHAENVSALLRY LSELLQSIGYRGSRQHIPPWDDELQTDLDELYDELAEEGEQDSLLDNDSDEDTLNNKLCT FSQTQKEFMNQHWYHCHTCNMINTVGVCSVCARVCHKGHDVSYAKYGNFFCDCGAKEDGS CQALSRRLGSGEVRDSAGVASYLPSHMSLLAGKKRSSPPAMQQVSAARKDSLNSERIAVL SKLLEPYRETLQHQEQWLLVVRCILEYFDLLLPSIRENCTLYSIVGCHKRATAALERLHQ LEQSFQVTDQLMFATLGSQEGAFENVRMNYSGDQGQTIKHLISSGVVRRVAFCCLSSPHG RRQQLAVSHEKGKVTILQLSALLKQADASKRKLTLTQLSSAPIACTVLSLAANPCNEDCL AVCGLKECHVLTFSSSGSTNEHIVVSPQLENGNYIKKAIWLPGSQTLLALVTSDYVKIYD LAVDSYSPKYYYLVALGKIRDCTFMYQDGQYYMLSFASSGYIYTQQLDQQSLAVHGDFYV TNTLELSHQHIKDVNGQVGGGGVSIYYSHTMQLLFYSYSSGRSFFSPLTNVNDGVKGIYH LDTNSASKSASKGPLQPLVQWTEVAGHPGLVYASMQTSNNPIILMLTPERIYLQEIKAQS AKSRIMDVVGIRHAVAGVEKTTLLLLCEDGSLRIFSAQPEHTSFWLSPQVQPFGNQLYSS TLMVKGGGCGVSAKPKSSAGPGKLTRKASQQQKQLTAGGLPVFPIDFFEHCNMLADVEFG GNDLLQIYNKQKLKTRLFSTGMFVASTRANGFTLEVINNDPNVVIVGIRVLIGTQDVQRA PLSVTILGRTVPTPVRRARWFDIPLTREEMFQSDKILKVVFAKSQDPEHVTLLDCIEVYG KSKELVGWPDESEEVTAPGSSVPAVPSTQASSANFGEGFNCITQLDRMVNHLLEVMDCAL NLLGSGVPAAIRQKAMKTASALLLLPTPNPVQTQARYVLATLYGSRPSYHSYKDGVLLQF VHGELQALHPKLEKLESLQEIDPEAFYRLILLVSGIANARPQSLAKICQENNYDIVPSIM SFVLELHKVTPALDEPTNIVRRGLCQAETIVHCLVEIMYGFALADPSQVGRMTKYFIDLL KHDASVISHSAKEALILLLSPRLKRRKVAIVTPPACSTPTPSTSTMQALQAVAASAASDI IEEAAAVAVDAAVGGSGGGGGGLPDPNPDAEGGVAGVGGVGQQQMLENLEAFMAFPRLLG LPEDADDEAIMDIAIALSLQQHEGDGNALQALLEGAPNLNGIRQAAVMAAAANAATASVS AGGSDDDEASNVATDGSTLRTSPAEPAGSGGSESGGSGVESIGGTSARSSNFGDHANASP PRQGSTKDDQEQPGPSGAACSGGASGLSAMSSSEDNEINEDDKLSKLHDLRIAVLESIIQ HLSTFDLCNGLQAIPLIQVILMLTTDLNGNNDRDQQVLQDLLSALVDYVEIGKRGAASRM ETKCPGNEVRLALLSLFGVMMGKTKSKQTGTTSPPHQFKDNTSFVASTTANVLSKSGAFV FALEALNTLLLHWKKVLGDPYAAGGGVSAAQAAQNSGSGGGASGSGVQLLKPIKHGPKPD ISILIPHNYLKNYPDIFESYDGLLTEIIVRLPYQILRLSSAHPDTYDSSFCESMTFTLCE YMMLNLNTLLRRQVRKLLMYICGSKEKFRMYRDGHSLDAHFRVVKRVCNIVSSKTGAPYN ANPPLLTYDSLVELTEHLRTCQEISQMRTGNWQKFCVVHEDALAMLMEIACYQLDDGVSP IIIQLLQAAVCNLPTGSNGSKLPQPLPSTSSSTSSKARSDREKSEDTDAYYSKFDPAQCG TFVHQIFRYACDALIIRFVRIFLLENNITQLRWQAHSFINGLFEHANERQREKLLNIFWN LWPLVPTYGRRTAQFVDLLGYLTLSTKSITDRLPEFVSRAVDVLRQQNELLCKHPNAPIY TTLESILQVNGYYLESEPCLVCNNPEVPMANIKLPSVKSDSKYTTTTMIYKLVQCHTISK LIVRIADLKRTKMVRTINVYYNNRSVQAVVELKNRPALWHKARSVSLQSAQTELKIDFPL PITACNLMIEFADFFETVSGSSENLQCPRCSAAVPAYPGVCGNCGENVFQCHKCRAINYD EKDPFLCHSCGFCKYAKFDFSMYARVCCAVDPIESAEDRVKTVSLIHSSLERADRIYRQL LTNKQMLELLIQKVAEHRSSDRLVEDNMASVHSTSQVNKIIQLLAQKYCVESRTSFEELS KIVQKVKACRSELVAYDRQQQDQPPINPGSSSGAEIPTTNRCYGCALASTEQCLTLLRAM AYNYDCRVGLYSQGLVSELAEHNLRRGTPQIQEEVRNLLVVLTKDNAEACMHLLQLVTAR VKNALMGSIPLISLEAAVHQEMTLLEVLLGQDDVCWEYKLKVIFELFISNCRLSRGPVTS VLHPCLRIMQNLICPVLPSSKPNQQKVATADLCSIKLLEGNTVDYRAWLNSDRNHEYAAW CSRMPKNSSQGKQKNAKEQAASAATEVPQKSRREVRATFLMEKFGKRWRERVLDKQRVTK PLVFNAKWIQPLLFNANSRFGRQLACSLLSSLSRTNERKQQALNMLTSFLKHVGEAGEAS AEYLMLFKSMSTEQPWLQYLVLKGVLGQISQLLAIEISKVHRMEEHSLSSDLSLGYALRQ YVELLWLLLECPNIRRTYKTRMLGPVLESYLALRSLVVQRTRLIDDAQEKLLEMLEDMTT GTEEETRAFMEILIDTVEKTRMNDIKTPVFIFERLYSIIHPEEHDESEFYMTLEKDPQQE DFLQGRMLGNPYPSSEMGLGPLMRDVKNKICTDCELIALLEDDNGMELLVNNKIISLDLP VKDVYKKVWLAEGGDRDAMRIVYRMRGLLGDATEEFVETLNNKSQEQVDTEQLYRMANVL ADCNGLRVMLDRIGSLQRISRNRELIQVLLKLFLICVKVRRCQEVLCQPEIGAINTLLKV LQMCLQSENDSIQSAVTEQLLEIMETILSKAASDTLDSFLQFSLTFGGPEYVTALISCTD CPNVRNNPSVLRHLIRVLAALVYGNEVKMALLCEHFRNTLSFKRFDKDRTPEEEFKMELF CVLTNQIEHNCIGGTLKDYIVSLGIVERSLAYITEHAPCVKPTLLRTDSDELKEFISRPS LKYILRFLTGLSNHHEATQVAISKDIIPIIHRLEQVSSDEHVGSLAENLLEALSTDAATA ARVQQVRDFTRAEKKRLAMATREKQLDALGMRTNEKGQVTAKGSILQKIEKLRDETGLTC FICREGYACQPEKVLGIYTFTKRCNVEEFELKSRKTIGYTTVTHFNVVHVDCHTSAIRLT RGRDEWERASLQNANTRCNGLLPLWGPAVGEAAFSGCMTRHSSYMQESTQRCDICYTSSV HDLKLLLVRFAWERSFHDDAGGGGPQSNMHFVPYLLFYAVYLLLSSRSASRDSKTLLTYL QAEPSEKWLECGYEVDGPLYMATVSLSLHSRELWNKHKLAHLKRLLAVAQARNISPSVLC KALLSPADRQVKDYSVYKPFLMMWALVDLIYNDLFNTVSTTKEEDWPISLFDYLRKNDEA MLKSTDNILKTLTDDFLTCTSFGEFCDVAGLLHLIEQPDTFIEGVLATLPSTTSSS NT seq 16011 nt NT seq  +upstreamnt  +downstreamnt atgtcggctcacagcggcggaacggattggaatttcgtggtaaaagcccttctgcaaaac cgcacaggagcccttaacaaaaacgaagtagttagtctgctaagagcgatcacgcgttgc gaacatgattttttcgacgaggaaagcagttacacccagttttacacggcctttgcagct ctggcggccgacaagcttatgcaaataaagacgatttgccagacgcaaatttgccaactg cacgatgccaccgcggttcttatccgtttcatcatctaccggttgcctcgtgtctcggtg tacgagaccaagtggttgctggtggcactcaagatgctttgcgagggcagggagaacgtc tccatgtcttcggttatgttcgactacaatgcggtggccaccgttctaaagagttgcaag catccagagtcgaccaccagcaaaagtatcctgccaagcagtagcagcagctcgtccagc ggtacgggcggcaatgcggacaaggagtcacctaaactggagataaagcgatcgcggtct gatctatcttctgtgatcctacagcaactgctggctccactagagccgggaaagatgacc tgggtgccgctaagcgaggaggtcactgactgcactgaccaacttttggcggccaacgtg gagtactttcaggaacagaatggagtcgacaccttgctggacgtatgtgtaggccttcct atactgaatcgctatcgctccaaatatctagagaccattaatggcggcaagccgctctac ctgccactgacgcaagtggaggccaccacagtgaaatcgaccatgaaccacatgctcacc gatctcaatatattgagtcaggctcatgctttgatagtgcttcagccgctcactcccagt cgaattgaacggttttcgagttgcggtatcgctgcactgtacaatgctgtgttggtatct ataaccgccagtgtgctcagcatgtgtcaaacgagtagcagctcccagaaacagagtgct gcttccaccagccagggaagcggtggcggagggggaggctcgagtactggacagagtaac aaggaccatgacgacttcgaggagcaggcctgcagtatagtgagcaaagctctggagatc tactctgccatcggagacctgttcaagtcgtcggcccgcatgcatgtgtatcaaaatcat ctgtgctacggcagctggctgcttatcagtggcatccaaggggccatgggtgcctccggg agtggcggagacacctcatcaaaatcagcaacgaaaacggccaagtctggaaacgaggcg acagctccaagtacacccatagccagggtcaatctcttcaaggtgcagcagggatttggg gagctcaatgcggccattgctaaccacagcatcaaactgctttcggaactaattgaagat ctaaagattgagtccgcctgtggaccgaatcccgagtccactgagctgccggcgccggca caattcgacatcctgcagagctatagttcgctggggaggattgtgagagtactgaatacc gccacgttgcaccagctcttcaccttcttggccacggttgcctaccgcaaggcctgcact caaagacgagcgtccgcaaaggatcgcgcggaatgtgagcccatcagctattcggactca accacctactttaacgactcgctttcctgctctgacaactccgaggaggacgatagtgaa agctacttgggacattggttcaaagagacactctccccggaaacacatgacgacaacgcc aatacatctgcccaagagaggagcggaggagagcaaaagagttcgcttgtccccaagctg gatgagccccatgaatatctggacttggcggcagatatattctgtttcctggacgaattt ctggccaataagcacgcctacatgcagcgctatgtgaaagcaggcgtcagcgatcagcaa atgctcctaatggccaatataatcaaggactttgacagggatgtgatgcgaaatgatagc gagcagggctcggggaatactccagcggccagtgcgggagcgggttcctctgcagcagca actaccaagtggcaaacggctatgattcgattttcgggctctgctggtagatacatccat aatctgatctccacttcactgctgtccgaacaactgcagtccaatttgctgcagcacttg gccatctcgccctggtcaacggatactagcacctggccattgcaggtctaccccagtacc ctttctgtgctggtccaaatcctgctcctgaagcccacccaggagaaggaggccgcctgc ctgtccgtgtggcatcgtcttatcaacaccctcgtcgagggagtctgtaactggtcggcc gctagttatactgactacgaggatctgaacattgagcacgcccagctgctcctcttcctc ttccactctctcaacctgatgcaaaagaagtcgatcctgttgctgacagccggcggcgta atacgctgcgcagaggtttgtcgcggcatcagcggagatcgacccgtgaagaacagccag atgatgctgctgtcgcggctgctgctgttcttggagtatctgatgaaacacttatacaac gcaccgccggaactgctcgatcaagttcggtggaatttgttcagcgtgagcagtatgcca gaaacgcagaagatcaccgatttgcttaatagtcgcaccaagttaaacttgtatttccgt caggacatcgaggagaggttccggaagtcagcgggggaatatggatctgcaattcgtccc acattctacacgttggtcatggccgatcccgaaaagccttactgggcacaggagtttaaa ttggatggcttggcctggaactttattctctgcactccggacaaacttaagtatcctctg ctagtggatgccctcacggatattctctcgattgtcgacatgtcggcgtttacaaaggac aaagaggccaaggatgcgaatatgcagagtctgtgtgcgatgcagtactgctttagcatc gcctggaagctgattttgggtctgccgccctccacctcgcatgtggagtcactgaaagta gagccagcacccaacttgcactcgttgatttggagcatacgctgtccattggccacctcg cactatctggtggtaaacagcctaattaagcagggcatgtacacccagtactcggaaacg ctgtggagggaggttggtgacattgcgggtgacttaaagtatagtctcaagcagaccata cttggcgtcgaagcgttcaatactcagatgaacggcaatggtactcctcgcctctccgat ctcatcttgtttgattcgttggtggctcacatgcaggccgtagcctgggctagcaaggag ggcttgaaactgccgcgcagagaaaccgatgaaatatcaagcgatcagtcctcttcagga gctgcagcctcgagcaacgatgccgatgtttactcttccaacgagtccatcgatgatgaa aaggcacagcaggaagaggaaagcgaactaccaagtgatctgcaaaaacataaccaatta gtgaacgagcttatgcttaagctaatgaactcctaccgcctgctctcggtcattgtacgc ggccagatgctgaaacagttgtccagctcgacgccggagcaagctcttaatctgatcgtc cccattgtgagtgataagcccgcgattatgctagagctgcatgcagcgtttctcaagctc ctcccgaatgaggacaagcaactgattgcgaacgagtggcccaagtgcctcatggtcaac gattccgctttcgacggcaagcagtttcccgtggaaccgtataccctgaacgtgatagac gcacatattatggagctgacgcgtggcgccaactactcaacgcttcacaccctaaagcac tgcctcaaatctatcctgcacttatttgagctccttctgccacattgctcgcatagcaac aatgagatggagtcgcagttgaaaggcttgctgattgcctccatgctagacatgcgaacc gactatctgcagggacagagcgagcagtgtctgcgagagattctcagcgggttgaccctg gaggcccagaaactgctgctctatgagcatatgattggctattgctatcgcatgcttaag gacttcgcagccgatcttcgccagacagcaccgccgctagatcaggagcgcgcaatgttc aatgagtccatgctgtttgcagtgctcaagactatgatcaagatggtggataaaccgact gggatgcaggctatgcggcagttcttcaaggatcagaaatcgggaagcctcaccaccctc ctgctctcctttactggaaccagtctacccgtcagctacgctcgcaagatgctgcagttc gttgagcgcctgttccagcagtcctcgcaagcggactcccagttcttgcacgacgattta gtcgaatgcttctcggagctggccaccgtcgatgtggcacgtctaaagctctggttggcc cacatcatctacgggcccaatgtgagtacggaagtgagcacatctgaggcaatggacacc acctgccgcctgctgaccagcatcatgcagccctccagcagctccagcagcaatgcccag actcccaccaatatggccacagtttctgccatgccgagtatctccgatcagctggatgcc atggaaattgactacgactgcggaacggcagcaggcggaggtggagaaagcggaaccggt gccggaggcgctggtggtgccaatacatcgcagatcctgagcctgtggcaggctgcgcag ccgaatccttcggaggaatcttcacaagcatgctgtgagcactcgggaactgaacgaaat ggagcgctcctactgagctttgtgaaatccttggttaaggatcagagcaaggcggcgcaa atagcgccgcccctgttccaggcattgctgcagctgggacagactttaatatccccgccc caggatgcttgcgactttgcggatgtgctccagataatgattacgttggcggatgccatt cccgcacgcggtcatgcggcattgttcaataccacggtcctgtggctggagctagaaaaa cagcagctaccggataagcagctgaggcacgcggagaatgtcagcgccctgctgcgttac ctcagcgaactcttgcagagcatcggctaccgcggaagccggcaacacattccgccctgg gatgatgagctgcagaccgatctggacgaactgtacgatgagctggccgaggaaggggaa caggactcgttgctggacaatgactccgacgaggatacgcttaacaacaagctttgtacc ttttcgcagacgcagaaggaattcatgaaccagcactggtaccattgccacacctgcaac atgattaacacggtgggcgtgtgctctgtctgcgctcgggtctgccacaagggacacgat gtaagttatgccaagtacggcaacttcttctgcgactgcggagccaaggaggacgggtcg tgccaagcactgagccggcgtcttggtagcggcgaggtgagagattcggccggagtggcc agctacttgccctctcatatgagcctcctggcaggcaagaagaggagtagcccacccgcc atgcagcaagtgtcggctgctcgcaaggattccttgaacagtgaaagaattgctgtgtta agtaagctcctagaaccgtatcgagagacacttcagcatcaggagcaatggctgctggtt gttcgctgcattctggagtactttgatttactattaccgtcgatccgggagaactgtacc ctctactccatcgtgggatgccataagagagcaacggcggcattagagcggctccatcag ctagagcaaagctttcaagtcacggatcaacttatgtttgctaccctgggctcccaggag ggtgccttcgagaacgtgcggatgaactactcgggagatcagggccagaccatcaagcat ctgatatcatccggagtggtgcgtcgcgtggccttctgttgtctttcctcaccacacgga cgtcgtcagcaactggcagtgtctcatgagaagggcaaagtgaccatccttcagctctct gcgctgctcaagcaggccgatgcctcaaagcgcaagttgactcttacccagctgagttcc gctcccatagcatgcacggtgctctcgttggccgccaatccctgcaatgaggattgccta gccgtttgcggtctgaaggagtgtcacgtgctcaccttttccagcagcggcagcacaaac gaacatattgtggtaagtccgcaactggagaatggaaactatatcaagaaggcgatctgg ctgcccggctcgcagactctcctggccctcgtcacctcggattatgtgaagatctacgat ctggctgtggattcgtacagcccgaagtactactacctcgtcgcattgggcaagatccgg gactgcacgttcatgtaccaggatggacagtactacatgttgagctttgccagctccgga tacatttacacccagcagttggaccagcagagcctggcggtgcatggagacttctatgtc accaatactctggagctgagtcaccagcacattaaggatgtcaatggccaagtcggcggc gggggagtttccatctactactcccacaccatgcagctgctattctacagctactcctcg ggcaggagcttcttctctccgctcaccaatgtgaatgacggcgtgaagggcatctatcat cttgataccaactcggccagcaagtctgcctcgaaaggacccctccagccgctggttcag tggactgaggtggccgggcatccgggactagtttacgccagcatgcagacatcaaacaac ccgattattctaatgcttacgccggaacggatatacctgcaggagataaaggcgcagtcg gcaaagtcgcgcattatggacgtggtgggcatccgacatgctgtggccggcgttgagaag accacactgttgctgctatgcgaggacggaagtctgagaatcttctccgcccagccggaa cacactagcttctggctgtcgcctcaggtccaaccctttggcaaccaactctactcatcc acactgatggtgaagggaggcggatgtggtgtcagtgcgaagcccaaatccagtgctggt cccggcaagctgacccgcaaggcgagccagcagcagaaacaactgacggccggcggacta cccgtgttccccatcgacttctttgagcactgcaatatgctagccgatgtggagtttggc gggaacgatctactccagatctacaacaaacagaaactaaaaacgcggctcttctccaca ggcatgtttgtggctagcacgcgagccaatggcttcaccctggaagtgatcaacaacgat cccaatgtggttatcgtgggcatcagggtgttgataggcacccaggatgtgcagagagca ccgctatcggtcaccattctgggacgaactgtacccacgccagtgaggcgcgcccgctgg ttcgacataccgctgacccgagaggagatgttccagtcggacaagattctgaaggtagtc tttgccaagtcccaggacccagaacacgtgacattgctggattgcatcgaggtctatggc aagtccaaggagctggtgggctggccagacgaatccgaggaagtgactgcaccgggatca agtgtgccggccgtgccctcaacacaggcaagcagcgctaactttggcgagggattcaat tgtatcacccagctggatcgtatggtgaatcaccttctggaggtgatggactgcgccctg aacttgctgggctccggagtgccagctgccatccgtcaaaaggctatgaaaacggcaagc gccctcctgctgttgcccacccccaatccagtccagacacaggcccgttatgtgctggcc accctctatggaagccggccgtcgtatcacagctacaaggatggtgtgctcctgcagttt gtgcacggagagctccaagctctgcacccgaaactcgaaaaactggaatctctgcaggag atcgacccagaggctttctatcgactgattctccttgtgagtggcattgccaacgctcgt ccgcagtcgctggccaagatctgccaggagaacaactacgacattgtgccatctatcatg agctttgtcctggagctgcacaaggttaccccggcgttggatgaacccacgaatattgtg cgacgcggcttatgccaggcggagactattgtccactgcctggtggagattatgtacgga tttgcgttggctgatccctcccaggtgggtcgcatgacgaagtactttattgatcttctc aagcacgatgccagtgtcattagccacagtgccaaggaggcgctgatcctgctactgagt ccccgattgaagcgccgtaaggtagctattgttacgccgccagcttgctccacgcccaca ccctcaacgtcaaccatgcaggctctgcaagcggtggcagcctcagcggccagtgacatc attgaggaagcggcagccgttgccgtcgatgctgcagttggagggagcggcggtggcggt ggtggtttgcctgaccccaatcccgacgcggagggaggtgttgctggcgtaggaggcgta ggtcagcagcagatgctggagaacctagaagccttcatggctttcccccgactgctcggc ctgcccgaggatgccgacgatgaggccatcatggacattgccatcgccttgagcttacaa cagcacgaaggagatggaaatgcgctccaggctctgctggagggtgctcccaatctcaat ggtattcgacaggcggcagtcatggcagctgcagccaatgcagcaacagccagtgtctcc gccgggggatctgatgacgacgaggcctctaacgtggccactgatggatcaaccttgcgg acatcgccagcagaaccagccggcagtggcggttcggagagtggcggcagcggagttgag agcattggaggaacatctgcgagaagcagcaactttggtgatcatgcgaacgcttcacct cctcgacagggctcaaccaaggatgaccaggagcagccaggtcccagcggggctgcttgt tccggcggggcctctggcctgagtgcaatgagcagcagtgaggataacgaaatcaacgag gatgataagctcagcaagctacatgatctgagaattgccgttctggagagcattatacaa cacctaagcacctttgatttgtgcaacggcctgcaggccattccacttatccaggtcata ctcatgctaaccaccgatcttaatgggaacaatgatcgagaccagcaagtactccaagat ctgcttagcgccctagttgactatgtcgaaattggcaagcgtggtgcggcgtcaaggatg gaaaccaagtgccctggcaacgaggtacgtctcgcattgctgtccctctttggtgtgatg atgggcaagactaagtcaaagcagactggcacaacctcaccgccgcatcagttcaaggac aacacatcctttgtggccagcaccacagctaatgttttaagcaaaagtggtgcctttgta ttcgccctggaggcccttaacactctgctgcttcactggaagaaagtgttgggcgacccc tatgccgcgggtggcggcgtgagcgccgcacaagctgctcaaaatagcggcagtggcggc ggagcttctggctcgggagtacagctactgaagcccattaaacatggtcctaaacccgac atatctatactgatcccgcacaactacctgaagaactatccggacatcttcgagtcctac gacggactgctgaccgagatcattgtccgcttgccttatcagattttacgtctaagcagc gctcatccggacacctacgacagtagcttctgcgagtccatgactttcaccctgtgcgag tacatgatgcttaacctgaacaccttgctgcgccgacaagtgaggaagctgctcatgtac atctgcggcagcaaggagaaattccgcatgtaccgtgatggacactcattggacgcccac ttccgtgtggtgaagcgtgtatgcaacattgtgagcagcaagactggtgccccatacaac gccaatccgcccttgcttacctacgattcgctggtggagctcacggaacatctgcgcaca tgccaggaaattagccaaatgcgcactgggaactggcagaagttttgcgtcgttcatgaa gacgctctggccatgctgatggagatagcttgctaccagttggatgacggcgtttccccc atcattatccagttgctgcaggcagctgtttgcaacctgcccactggttccaatgggtca aagttgccgcagcccctgccttcgacctcctcctcgacatcgagcaaggcgcgaagtgac cgggagaagagtgaggatacagacgcctactactccaagttcgatccagctcagtgtggc acattcgtgcaccaaatcttcaggtatgcttgcgacgccttaatcatccgttttgtaagg atcttcctgctcgagaacaacatcacccaactgaggtggcaggcccattcctttataaac gggctcttcgagcatgccaacgagaggcagcgtgagaagttgttgaatatcttctggaat ctttggccactggtgcccacttacggtcggaggacggcgcagtttgtggatctgctgggc tatctaacactaagcaccaaaagcatcacagaccgcctgccggaattcgtgtcgcgtgcc gtggatgtgctccggcagcagaacgaactgctctgcaagcatcccaatgcgcccatatac accaccttggagtctatactgcaggtgaatggctactatctggagtcagagccgtgtctg gtgtgcaacaatccagaagtgccgatggcaaacatcaagctgccgtcggtcaagtcggac tcaaaatacaccacgaccacaatgatttacaagctggtgcagtgccacactatctctaag ctgattgtacggatagccgacctaaaacgcaccaagatggtgaggactattaatgtttac tacaacaatcgcagtgtccaggcggtggtggagctgaagaatcgaccagcgctgtggcat aaagcgcgctctgtctctctgcaatcggcccagactgaactaaagatcgacttcccacta ccgatcaccgcctgcaatttgatgatcgagtttgcggacttttttgagaccgttagcggt tccagcgagaatctacagtgtcccagatgcagtgcagcagtgcccgcatatccgggagtc tgtggcaattgcggtgaaaacgtgttccagtgccacaagtgtcgagccattaactacgac gagaaggatcccttcctctgccattcatgtggcttctgcaaatacgccaagttcgatttc agcatgtatgctcgagtctgctgtgcggtggatcccattgagtcggccgaggatagggtg aagactgtatcgctgatacatagctcattggagagagcggacaggatataccgccagctg ctgaccaacaagcagatgctggagttgctcatacagaaggtggccgagcacagaagcagc gatcgcctcgttgaggacaacatggccagcgttcacagcacctcacaggtcaacaagatt atccagctcttggcccaaaagtattgcgtggagtctcgcaccagcttcgaggaactgagc aagattgtccagaaggtgaaggcgtgtcgtagtgaattggtggcctacgatcgacaacaa caggatcagccgccgattaatccgggatcgtcttccggcgccgaaattcccaccacaaat cgctgctatggttgtgcattggcctccactgagcagtgtctgaccctcttgcgggctatg gcctacaactacgattgtcgcgtcggtttgtatagtcaaggactcgttagcgaactagcc gagcacaatctgcgacggggcactccgcagattcaggaggaggttcgaaacctattggtt gtgctgaccaaggacaatgccgaggcctgcatgcacctgctgcagctggtaacagctagg gtgaagaatgccctaatgggatcgattccgttgatcagcctggaggctgccgttcatcag gagatgaccctactggaggtgttgctcggccaggacgatgtgtgctgggaatacaagcta aaagtcatctttgagctgttcattagtaactgccggctgtcccgtggccccgtgacatcg gtgctccatccctgccttcggataatgcagaatctcatctgcccggtgctgcccagcagc aagcccaaccagcagaaggtggccaccgctgatctctgcagcataaagctgctcgaaggc aacaccgttgactaccgggcctggctcaactcggatcggaaccacgagtacgccgcatgg tgcagccgaatgccgaagaacagtagtcagggcaagcaaaagaacgccaaggagcaggcg gcttcagcagccacagaggtaccgcagaagagcaggcgagaggtgcgggcaaccttcctg atggagaaattcggaaaacgatggcgggagcgtgtgctggacaagcagcgagtaacaaag cccctcgtatttaatgccaaatggattcagcccttgctgtttaatgccaactcccggttt ggacgccagttggcctgctccctgctgagcagtctgagcagaaccaacgagaggaagcaa caggccttgaatatgctcacctcgttcctgaagcacgtgggcgaagccggcgaggccagt gccgaatacttgatgctcttcaagagcatgtccacggagcagccatggctgcagtatctc gtgctgaagggtgtcctgggccagatatcccagctgcttgcgattgagataagcaaggtt catcggatggaagagcactccctctcctcggatctgtccctaggctacgcgttgcgccaa tatgtggagctgttgtggctgctccttgaatgccccaacattcgaagaacctacaagacc cgcatgctgggccccgttctcgagagctatctcgccttaaggagtctggtggtgcagcgc acgcgactgattgatgacgcccaggaaaagctgctcgagatgctagaggatatgaccacc ggcacagaggaggagacgcgtgcatttatggaaattctcatcgataccgtggaaaagacg cgaatgaatgacatcaagacacctgtgttcatcttcgagcggttgtattccatcattcat cccgaggagcacgacgaaagcgagttttacatgacgttggagaaggatccgcagcaggag gacttcctgcagggccgtatgctgggtaacccgtatccctcgagcgaaatgggcctgggg ccgctgatgcgcgacgtcaaaaacaagatctgcacggactgtgaactgatcgccttgctg gaggacgacaacggtatggagctgctggtaaacaacaagatcatcagcctggatctgccc gtcaaggatgtgtacaagaaggtgtggttagcagagggcggcgatagggatgccatgagg atagtctatcgcatgcgtggtctcctgggcgacgctaccgaggagtttgtggagacgctg aacaacaagagccaggagcaggtggacaccgagcagctgtaccgaatggccaatgtcctg gccgactgcaacggcctccgtgtgatgctggaccgtatcggcagcctgcagcgcatctcg cgcaaccgcgaactcatccaggttttgctaaagctcttcctcatctgcgtaaaggtgcgt cgctgccaggaagtgctgtgccagcccgaaattggagccatcaacactttgctcaaggtg ctacagatgtgtctgcagtcggagaacgattccattcagtcggcggtcaccgagcagttg ctagagatcatggagactattctctcgaaggcggctagcgatacactggactccttcctg cagttctcgctgaccttcggtggacccgagtacgtgactgctcttatctcctgcacagat tgtccgaacgtaaggaataatccctcggtgctgcgccatctcatccgggttctagccgcc ttggtctacgggaacgaggtgaagatggccctgctctgcgagcactttaggaacaccttg agctttaaacgcttcgacaaggaccgcacgccagaagaggagttcaaaatggagctcttt tgcgtgctgaccaaccaaatcgagcataactgcatcggcggcacactcaaggactacatt gtaagccttggcatcgtggaacgatccctggcctacatcaccgagcatgctccctgcgtt aagcccacactcctgcgcaccgactccgatgagctgaaggagttcatttcacgtccgagc ttaaagtacatcctccgcttccttaccggcctctcgaatcatcacgaggccacccaggtg gccatcagcaaggacattatacccattatccaccgcctagagcaagtctccagtgacgag cacgttggcagcctggctgagaaccttttggaggcgctctccacggacgcggcaacggca gcaagggtgcaacaagtgcgggacttcaccagggcggagaaaaagcgactggccatggct acgcgagagaagcaactggatgccttgggaatgcgtacgaatgaaaagggtcaggtaacg gcaaagggctctatcctgcagaagatcgaaaagctgcgcgatgagacgggcctaacgtgc ttcatttgccgcgaaggatacgcctgccagccagaaaaggttctgggcatctacacgttc accaagcgatgcaatgttgaggagttcgagctcaagtcgaggaagaccatcggctacacc accgtcacccacttcaatgtggtccacgttgactgtcatacatctgccatacgcctgact cgcgggagagacgagtgggaacgagctagtctacagaatgccaacaccaggtgtaatggc cttctgcccctttggggtcccgccgtaggggaggcagccttttctggctgcatgacccgg cacagcagctacatgcaggagagcacccagcgctgcgacatctgctacacgagcagcgtg catgacctgaagctgctgctggtgcggttcgcctgggagcgaagcttccacgacgatgct ggcggcggaggtccccagtcaaacatgcactttgtgccctacctgctcttctacgccgtc tacctgctgctctcctcccgctcagcgtccagggatagcaagacgttgctgacatatttg caggcggagccaagcgaaaagtggctagagtgtggatacgaagtagacggccccctgtac atggctaccgtttccctgtcgctgcacagtcgtgagctgtggaacaagcacaagctggca catctcaagcgccttttggcggtggcacaagcccgtaacatctcaccctcggttctatgc aaggccctgttgtcgccggcggatcgtcaagtcaaggattacagtgtatacaagccgttc cttatgatgtgggcactggtggacttgatctacaatgaccttttcaatacggtgagcacg accaaggaggaggattggccgatttcgctgttcgactatctgcgcaagaacgatgaggct atgctgaagtccacggacaacatcctgaagaccctgaccgatgacttcctgacctgcacc tcctttggggaattctgcgatgtggcaggccttctacatctcattgagcagcccgacacc ttcattgagggggtcctcgcaaccctgccttcaaccacgagctctagttaa

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