Drosophila serrata: 110189240 Help Entry 110189240         CDS       T06108                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism dsr  Drosophila serrata Brite KEGG Orthology (KO) [BR:dsr00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:dsr04040]     110189240    04990 Domain-containing proteins not elsewhere classified [BR:dsr04990]     110189240 Ion channels [BR:dsr04040]  Voltage-gated cation channels   Ryanodine receptor    110189240 Domain-containing proteins not elsewhere classified [BR:dsr04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    110189240 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  110189240 NCBI-ProteinID:  XP_020814883 LinkDB All DBs Position Unknown AA seq 5136 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVTLSCTATGERVCLAAEGFGNRHCFLENIADKNVPPDLS QCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHHNSDMYLACLSTS SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE NEQSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGREPG TNIVIYEGGVVMAQARSLWRLELARTKWTGGFINWYHPMRIRHITTGRYLGVNESNELIL VKKEEASIATTTFCLRQEKDDEKKVLEDKDLEVIGSPIIKYGDTTVIVQHCETSLWLSYK SYETKKKGVGKVEEKQAILHEEGKMDDCLDFSRSQEEESKTARVIRKCSSLFTQFITALE TLQSNRRHSIFFQKVNLNEMVMCLEDLINYFSQPEDDMEHEEKQNRFRALRNRQDLFQEE GVLNLILEAIDKINIITSQGFLASFLAGDETGQSWDLISTYLYQLLAAIIKGNHTNCAQF ANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTLLVDHVASIRPNIFVGRVDGS SMYQKWYFEVTMDHIEQTTHMMPHLRIGWANTSGYVPYPGGGKKWGGNGVGDDLYSFGFD GANFWTGGRKTPVVDALPEEPFIRKGDVIGVAIDLSVPIITFTFNGVKVRGSFRDFNLDG MFFPVMSCSSKLSCRFLFGGDHGRLKFAPPMGFSALVQCLMPHQILSLDPCFYFGNLSKN VLAGPWLIEDDTAFVPKPVDTTGVTLPSSVDQIKEKLAENIHEMWALNKIEAGWSWGEHR DDYHRIHPCLTQFEKLPPAEKRYDNQLAVQTLKTIISLGYYITMDKPPARIRPVRLPNEI FMQGNGYKPAPLDLSAVTLTPKLEELVDQLAENTHNLWARERIQQGWTYGLNEDSDNHRS PHLVPYGKVDEAIKKANRDTASETVRTLLVYGYVLDPPTGEGTEALLAEAQRLKFAAFRT YRVERNYAVTSGKWYFEFEVLTAGPMRVGWARADCYPGAMLGSEDTSWAFDGHNEEKVYG GVSESFGKQCGPGDIVGVFLDLADHTISFSLNGELLMDALGGETTFADVTAEGVGFVPAC TLGVGQKARLIYGQDVDSLKFFTTCGLQEGYEPFCVNMRRPVTHWYTKDQPIFENTEEMP DCRIDVTRIPGGADTPPHLKISHNTFETMEKANWEFLRLSLPVTCMSEFINEQEKARRWD EIKNRQYRLMREAEAAAQMAVQTQAAHMDHMLKGGFNMNDIKGLTRNFDEHADAEADHMM RGPSRPPRKGSLTRNITFETDMSAALDEMQRSTSVLDMNGLGDELDDKKKRGRSPFKFFS KKSRDQSREKMGSRTLDTSLERRNTVAHGRNVVNQQMTTRAPTLRLNNADIPPSPVAQGG PKQLSGSNLGQPPIEGSGEEMFDAECLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHLH SKEFNKNKVRRGSVYIEDDYEMAIERIDRQSCYVVRADELFNEVTQDASGKGASQGMFVG CFVDTATGIIRFTCEGKETSHRWMMEPDTKLFPAIFVEATSKEILQIELGRTPTTLPLSA AVLPTSDKHISPQSPPRLKVQCLRPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSML ALHIPEEDRCIDILELIEMDKLLSFHAHSLTLYAALCYQSNYRAAHALCQHVDQKQLLYA IRSEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYITPLGPELKELYSEAEMQHSLRS LVTESVRPQLRMTEITPPVIATSSMPSVSSEPIPNIDQLYSPKFPLEVVRQFVMEALKDA VEINQVHNRDPIGWTNENLFLPLIKLTDRLLLVGVLTDEDVQRLLVMIDPETWDAAFERE GKDEHRKGLLTMKMAEGAKLQMCYLLHHLYDTQLRHRVESIIAFSHDFVGDLQTDQLRRY IEIKQSDLPSAVAAKKTKEFRCPPREQMNQILCFKNLEPDDQDNCTCGLELRSRLGDFHD FLMQKVSLNALQEPDGVEGAAIEEIKTGPITKIYNFINTVKELEEGPKEVEEPEKKTPEE VFRKVLIKTIVSWAEESQIENPKLVREMFSLLLRQYDTVGELVRALEKTYVINNRARDDV AEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNATFFQHPDLIRILRVHENVMAVMM NTLGRRAQAQSDAPTQTEGAEGVPSKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDHF DFLLDNANILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNS ELVEKGYPDLGWDPVEGERYLDFLRYCVWVNGESVEENANLVIRLLIRRPECLGPALRGE GEGLFRAIVEANRMSERISDRCKMQDEAEGTIAGLNFTHPLPEGEEDEDYIDTGAAILNF YCTLVDLLGRCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLSLKFTLSQTAPGEEK PKSDMPSGLLPNNKQSIVLFLERVYGIETQDLFYRLLEDAFLPDLRTATILDKSDGSESD MALAMNRYIGNSILPLLIKHSKFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSD FLVALTSQMQPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHFDRCAKYYGSTQGQGSYG ASSDEEKRLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNTDEDYY GRQMGAPDQPQYMPNPIDTNNVHLDNDLNSLVQKFSEHYHDAWASRRLEGGWTHGDIRSD NDRKHPRLKPYNMLSEYERERYRDPVRECLKGLLAIGWTVEHSEVEVPLNHRGSTRRQSK PQIHEFQNEGSPFNYNPHPVDMSNLTLSREMQNMAERLAENSHDIWAKKKNEELNGCGGV IHPQLVPYDLLTDKEKKKDRERSQEFLKYMQYQGYKLHKPSKGGAVEEGGATQAAVELRF SYSLLEKLIQYLDRATINMKLLKPSTTFSRRSSFKTATRDIKFFSKVVLPLMEKYFSTHR NYFIAIATATNNIGAASLKEKEMVASIFCKLAALLRNRLSAFGPDVRITVRCLQVLVKGI DARTLTKNCPEFIRTSMLTFFNQTSDDLGNTILNLQDGKYSHLRGTHLKTSTSLGYVNQV VLPVLTAMFDHLAACDYGSDLLLDEIQVASYKILAALYHLGTDATLTHDRKYLKTEIERH RPALGSCLGAYSSCFPVAYLEPHLNKHNQYSLLNRIADHSLEAQDIMVKMESCMPNLETI LAEVDQFVESDKTYNDAPHIIDVILPLLCAYLPFWWSQGPDNVSPTSGNHVTMVTADHMN PLLRNVLKMIKKNIGNDNAPWMTRIAAYTQQIIINTSEELLKDPFLPLAERVKKRTENML HKEDSMRGFIKSATDDTSQVETQLQEDWNLLVRDIYSFYPLLIKYVDLQRNHWLKDNIPE AEELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMALIMPTATRRSAISEGVPAVGGK VKKKKKNRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRYLKKMPEY DVIEFARMQLTLPDKLDPSDEMSWQHYLYSKLGKTEEPVDEQALEKANVNANEKGKDKTQ ETVDRIVAMAKVLFGLHMIDHPQQQSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRAC NIFARSYYEQWLQEENVGQEVMVEDLTQTFEDSEKSKKDEEETDSKPDPLTQLVTTFCRG AMTERSGALQEDLLYMSYAQIAAKSCGEEEEEGGDEEGGEGGEEGEGTSIHEQEMEKQKL LFHQARLSNRGVAEMVLLHISASKGIPSEMVMTTLNLGIAILRGGNIDIQMGMLNHLKEK KDVGFFTSIAGLMNSCSVLDLDAFERNTKAEEYIPSAGAGLGVGSEGAAGEKNMHDAEFT CALFRFIQLTCEGHNLEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKE IIDPAGKANFFKAIGVASQVFNTLTEVIQGPCTLNQQALAHSRLWDAVGGFLFLFSHMQD KLSKHSSQVDLLKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKY FDMFLKLADLIESPSFHEIDMKNEGWVTPKDFREKMEQSKNYTPEEMDFLLACCERNHEG KIDYRAFVERFHEPSKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRI EILGSSKRIERVYFEIKDSNIEQWEKPQIRESKRAFFYSIVTEGGDKEKLEAFVNFCEDA IFEMTHASGLMATDDGGGNVKRDTAYSSYMSEEEEERAARDPIRRTITAVKEGLKFGVHM LSPANIKHQIGVMQTKSIPELIVGFFKIIFYIFYYTGYAHFCVVRYIFGILLNLMRGPAP EQEEEPVVEEETFGRALPPLPLEEPPGTVQAFGLDINKEENGMYKVVVHESPANSSMEEG GESSPEDGTAITGELAEGEPHQEPISIVDLLGGEAAKKAAQERQEAQKAQEAAMASIEAE AKKSSAAPQETPAVHQIDFSQYTHRAVSFLARNFYNLKYVALVLAFSINFMLLFYKVTSF AEEGESSGEEELILGSGSGAGADITGSGFGGSGDGGSGDGEMEDEIPELVHVDEDFFYME HVLRMAACLHSLVSLAMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPEDDDFKSH WDKLVISAKSFPVNYWDKFVKKKVRQKYSETYDFDSISNLLGMEKSAFTAQESEETGIFK YIMNIDWRYQVWKAGVTFTDNAFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTI LQSVTHNGKQLVLTVMLLTIIVYIYTVIAFNFFRKFYIQEEDEEVDKKCHDMLTCFVFHL YKGVRAGGGIGDEIGDPDGDDYEVYRIIFDITFFFFVIIILLAIIQGLIIDAFGELRDQL ESVKDNMESNCFICGMGKDFFDIVPHGFDTHVQKEHNLANYMFFLMHLINKPDTEYTGQE TYVWNMYQQRSWDFFPVGDCFRKQYEDELSGGGGGG NT seq 15411 nt NT seq  +upstreamnt  +downstreamnt atggctgaggcggagggaggctccgagcaggatgatgtttcattccttagaacggaggac atggtcacgctctcctgcacggcgacgggggagcgtgtctgcttggccgccgagggattt ggtaaccggcactgtttcctcgagaacattgccgacaagaatgtgccgccggatctgtcg cagtgcgtcttcgtcatcgagcaggcgctgtccgtgcgtgctctgcaggagctggtgacg gcggccggatccgagacgggcaagggaaccggatcgggacataggacattgctctacggc aatgccattttgctccgccatcacaacagtgatatgtacttggcctgcctgtccacgtcc tcgtcgaacgacaagctgtccttcgacgtgggtctgcaggagcacagccagggcgaggcc tgctggtggacagtgcatccggcgagcaagcagcgctccgagggcgagaaggtgcgcgtc ggagacgatttgatcctggtgtcggtggccaccgaacgctatctgcacaccaccaaggag aacgagcaatcgatcgtgaatgccagcttccacgtcacccactggtctgtgcagccttac ggcaccggtatctccaggatgaagtatgtgggctatgtctttggtggcgatgtactgcga ttctttcacggcggcgacgagtgcctgaccatacccagtacctggggtcgtgagccagga acaaacattgtaatttacgagggcggcgtggtcatggcccaggcacgttccctgtggcgc ctggaactggcacgaaccaagtggaccggcggcttcatcaactggtaccatccgatgcgc attcgccacataaccactggacgctatttgggcgtcaacgaaagcaacgaactgatcctg gtgaagaaggaggaggcctcgatcgcgacgacgactttctgcctgcggcaggaaaaggac gacgagaagaaggtgctcgaggacaaggacctggaagtgatcggctcgccgatcattaag tacggtgacaccaccgtcattgttcagcattgtgagacaagcctgtggctcagctacaag agctatgagacgaaaaagaagggcgttggcaaggtcgaggagaagcaggccattttgcat gaggagggcaagatggacgattgcctcgacttttcacgctctcaggaggaggagtccaag acagcgcgtgttatccgcaagtgcagcagtctcttcacccagtttattacggccttggaa acgctgcagtccaaccgacgacactccattttcttccaaaaggtcaacctcaacgagatg gtcatgtgcctggaggacttgatcaattacttctcgcaacccgaagacgacatggaacac gaggagaaacagaaccgcttccgtgctttgcgcaaccgtcaagatctgttccaggaggag ggcgtgctcaacctcatactggaggccattgacaagatcaacatcattacctcgcagggc ttccttgccagctttctggccggcgacgagactggccagagctgggacctaatttccacc tacctgtaccaactgctggctgccatcatcaagggcaaccacacgaactgcgctcaattc gctaacagcaaccgcttgaactggcttttttcgcgtctgggctcgcaggcctccagcgaa ggatccggcatgctggacgtacttcactgcgtgctcatcgactcacccgaagccctgaac atgatgcgggacgagcacatcaaggtgatcatctcgctgctggagaagcacggcagggat cccaaggtcctggatgtactctgctccctgtgcgtgggtaacggcgtggccgtgcgctcc tcgcagaacaacatctgcgacttcctgctgccaggcaagaacctgctgttgcagaccctc ctggtggatcacgtggccagcatccgaccaaacatctttgtgggccgcgtagacggttcg tccatgtaccagaaatggtactttgaggtgaccatggaccacatcgagcagacgacacat atgatgccccatctgcgcattggttgggccaacacctccggctatgtcccgtaccctggc ggcggcaagaaatggggtggcaatggcgtgggcgacgacctatactccttcggttttgat ggtgccaacttttggaccggaggaaggaagactcccgtggtagacgctctgccagaggag cccttcatccgcaagggcgatgtgattggcgtggccatcgatctctcggtgcccattatc acgttcaccttcaatggcgtcaaggtgcgtggtagcttccgggactttaacctggacgga atgttcttcccggtgatgagctgctcctcgaagctcagttgccgcttcctctttggcggc gatcatggccgcctaaagtttgccccgcctatgggattctcagcgctggtccagtgtctt atgccgcatcagattttgagcctggacccatgcttttactttggcaatctcagcaagaac gtccttgccggaccctggcttatcgaggacgacactgcctttgtccctaagccggtggac accaccggagtgactctgcccagctctgtggatcagatcaaggagaagctggcggagaac atccacgagatgtgggcgctgaacaagatcgaggctggctggtcgtggggggagcaccgt gacgactaccatcgtattcatccctgcctcacccaatttgagaagctgcctccggcagag aagcgatacgataatcaattagctgtgcaaacactcaagaccatcatttcattaggttac tacataaccatggataagccgccggcacgcatccgtccagtgcgcctgcccaacgagatt ttcatgcagggcaacggctacaagccggctcccctcgaccttagcgccgtgaccctaacg ccaaagctggaggagctggtggaccagctggcggagaacacgcacaacctgtgggcgcga gagcgcattcagcagggctggacttatggtctgaacgaggacagcgataaccatcgcagt ccccacttggtgccgtatggcaaggtggacgaagctattaagaaggccaaccgtgatacg gcctcggagacagtgcgaacacttctggtctatgggtacgttctggatccaccaacgggt gagggcacagaggcccttctggcggaggcacagcgtctgaagtttgccgccttccggacc tatcgcgtggagcgcaactacgccgtgacctctggcaagtggtacttcgagttcgaggtc cttaccgccggacctatgcgcgtgggatgggcacgagcggactgctatccgggagccatg ctgggcagcgaggacaccagctgggccttcgatggccacaacgaagagaaagtctacggt ggcgtcagtgagtccttcggtaaacagtgcggacccggggacatagtcggcgtctttcta gacctcgcggatcacacaattagcttctccctcaacggagaactcctcatggacgccctg ggcggcgagacgacctttgccgatgttactgccgaaggagtgggctttgtgccagcctgc accctgggcgtgggccagaaggcgcgcctcatctatggccaggacgtggactccctcaag ttctttaccacctgtggcctgcaagagggctacgaacccttctgcgtgaacatgcgtcgt ccggtgacccattggtacaccaaagatcaacccattttcgagaacaccgaagagatgccc gactgccgcatcgatgtcacccgaattcccggtggtgcagataccccgccgcatttgaaa atctcgcacaacaccttcgagaccatggagaaggccaactgggagttcctgcgtctttcc ctcccggtgacctgcatgagtgagtttatcaatgagcaggagaaggcccgacgctgggac gagatcaagaaccgacagtaccgtctgatgcgcgaggcagaggctgctgctcagatggcg gtgcagacccaggccgcccatatggatcacatgctcaagggaggcttcaatatgaatgac atcaagggtctgacccggaactttgatgagcatgcggatgccgaggcggatcacatgatg cgaggaccatcgcgtccaccgcgtaagggttctctgacccgtaacatcaccttcgagacg gacatgtccgccgccctagacgagatgcagcgctccacctctgtgctggacatgaatgga ttgggcgacgagttggacgacaagaagaaacgcggtcgtagtcccttcaagttcttctca aagaagtcacgcgaccagagccgtgagaagatgggctcccgcaccctggacacctcgctg gagcgtcgcaacacggtggcccatggaagaaacgtggtgaaccagcagatgaccacgagg gcacccactctacggcttaataatgccgacatcccgcccagtcccgtggcccagggtgga cccaagcagctgagtggctcgaatctcggccagccaccgattgaaggttccggggaagag atgttcgatgcggagtgcctgaagctaatcaacgagtacttctacggcgttcgcatcttc cctggccaggatcccacgcacgtgtacgtgggctgggtgactacccagtaccatctgcac agcaaggaattcaacaagaacaaggtgcgtcgcggatcggtgtacatcgaggacgactac gagatggccatcgagaggattgaccgccagagttgctatgtggtgcgggcggacgagctc ttcaacgaggtgacccaggatgcctccggcaagggagcatcgcagggcatgttcgtgggc tgcttcgtggatacagccactggcatcatccgcttcacatgcgagggcaaggagacctcc caccgctggatgatggagccggacaccaagcttttcccggccatcttcgtggaggcgacc agcaaggagatccttcaaatcgaactgggacgcactcccaccacgctgcccctgtctgcc gctgtgctgcccaccagtgacaagcacatcagtccgcagtcgccgccgcgtctcaaggtc cagtgcctgcgtccgcatcagtgggcccgtgtgccaaacaccgcactccaagtacatgcc ctcaagctgtccgacatccggggctggtccatgctgtgcgaggatccagtgtccatgctg gcgctgcacatccctgaggaggatcgctgcatcgacattctggagctgattgagatggac aagctgttgtccttccatgctcacagtctcaccctgtacgcggcattgtgctatcagtcc aactatagggctgcgcatgccctgtgccagcatgtggaccagaagcaactgctctacgcc atcaggtcggagtacatgagcggacccctgcggcagggcttctatgacctgttgattgct ctgcatctggaatcacatgccaccacaatggaggtgtgtaagaacgagtacatcactccc ctgggaccggagctgaaggagctgtacagcgaggcagagatgcagcattcgctgcgttcc ctggtcacagaatcagtgcggccgcagcttaggatgacggagatcacaccccctgtgatt gcaacatctagtatgccaagtgtttccagcgaaccgatccccaacatcgaccaattgtac tccccgaagttccccctagaagtagtcaggcagttcgtgatggaggccctgaaggacgcc gtcgagatcaaccaggtccacaatcgcgatcccatcggctggaccaacgagaacctgttc ctcccgctcatcaagctgacagatcgcctgctcctggtcggcgtcctgaccgatgaggat gtgcagcggctgttggtcatgatcgatccagagacctgggatgccgccttcgagagggag ggcaaggacgaacaccgcaagggcttgctcacaatgaagatggccgagggagccaagttg cagatgtgctacctgctgcatcacctgtatgacacccagttgcggcatcgcgtggaaagc atcatcgccttctcgcacgacttcgtgggggatctgcagaccgatcagttgcgacgttat atcgagatcaagcaatccgatctgcccagtgctgtggcggccaaaaagactaaagagttc cgctgtccgccgcgggagcagatgaaccagattctctgcttcaagaacctcgagcccgac gaccaggacaactgcacctgcggccttgagttgcgcagccgcctgggtgatttccacgat ttcctcatgcagaaggtttcgcttaacgctctccaggagccagatggcgtcgaaggcgcg gcgatcgaggagattaagacggggcccataacaaagatctacaacttcatcaacaccgtc aaggagctggaggaagggcccaaggaggtggaggagccagagaagaaaacgcccgaggag gtgttccgcaaggtgctcatcaagaccatcgttagctgggccgaggaatcacagatcgag aatcccaagctcgtacgcgaaatgttcagtttgctgctgcgtcaatatgacaccgtgggt gagctggtccgtgccctagagaagacctacgtgatcaataaccgagcgcgtgacgacgtg gccgagatgtgggtcggactaagccaaattcgcgccctactgcccgtccagatgagccag gaggaggaggaactgatgcgtaagcgcctgtggaagctggtaaacaatgccaccttcttc cagcacccggatctcatacggatcctacgcgttcacgagaacgtaatggccgtgatgatg aacacactgggacggcgggcacaggcgcagagcgatgccccgacccaaactgagggcgcc gaaggggttccgtccaaggagaaggacacctcgcacgagatggtggtggcctgctgccgg ttcctctgctacttctgccgtacgggccggcagaaccagaaggccatgttcgatcacttc gactttttgctggacaacgccaacatcctgctggcacgacccagccttcgcggctccacg ccactggacgtggcctactcgagtctgatggagaacacagaattggctctggcactgagg gaacactatctggagaagatcgccgtctatctgtcgcggtgcggcctccagagcaactcg gagctcgtggagaaaggctatccggacctgggctgggatcccgtggagggagagcgctac ctggacttcctgcgctactgcgtttgggtcaacggcgagagcgtcgaggagaatgcgaac cttgtcattcgacttcttatccgtcgtccggaatgcctgggaccggctctaagaggagaa ggagaaggtctgttccgcgccatcgtcgaggccaatcgcatgtcggagcgcatctcggac cgctgcaagatgcaggacgaggccgagggcaccattgccggcctgaacttcacccatccg ctgcctgagggagaggaggatgaggactacattgacaccggtgccgccatcctgaacttc tactgtactttggtggacctgctgggccgctgtgcaccggatgcctcggtcattgagcag ggcaaaaacgagtccctgagagccagagctattctgagatctctggtgccgctggaggat ctccagggtgtgcttagcctgaagtttaccctgtcgcagacggcacccggtgaggaaaag cccaagtcggacatgccgtcgggcctgctgcccaacaataaacagagcatcgtgctcttc ctggagcgtgtctatggcatcgagacgcaggatctcttctatcgcctactggaggatgcc ttccttcccgacctgcgcaccgccaccattctggacaagagcgatggctccgagagtgac atggccctggccatgaatcgctacattggcaactctatcctgccgctgctgatcaagcac tccaagttctacaacgaggccgagaactacgccagcctcttggatgccacattgcacacg gtctaccggctgtccaagaaccgtatgctcaccaaggggcagcgcgaggcggtctccgac ttcctggtggccctcacatcccaaatgcaacctgccatgctgctcaagctgctgcgcaag ttgactgtggatgtgtccaagctgtccgaatacaccaccgtggccctccggctccttacc ctgcacttcgatcgctgcgccaagtattacggctcaactcaaggccagggctcgtatggg gcgtcctcggacgaggagaagcgtttgaccatgctgctgttctcgaacatttttgactcg ctcagcaacatggactatgacccggaactgttcggtaaggccctgccctgcctgattgcc atcggctgtgccttgccccccgactacagtctgtcgaagaacacggacgaggactactat ggccgccagatgggagctcccgaccagccgcaatatatgcctaatccgattgacactaac aatgtccacctggacaatgacctcaactcgctggtccagaagttcagcgagcattaccac gatgcctgggccagcaggcgtctcgaaggtggatggactcacggggacatccgatccgac aacgatcgcaagcatccacgtctgaagccatataacatgctcagtgaatatgaacgtgag cgttaccgggatccagtgcgtgagtgcctcaagggtctcctggccattggctggactgtg gagcactccgaggtggaggtgccgctgaatcatcgtggatcgacgcgtcgccagtcgaag ccccagattcacgaattccagaatgagggcagtcccttcaactacaacccgcacccggtg gacatgagcaacctgaccctgagcagggaaatgcagaacatggccgagcgcctggcggag aattcccacgacatttgggccaagaagaagaacgaggagctgaatggctgtggaggagtc atccacccccagctggtgccctacgacctgctgaccgacaaggagaagaagaaggatcgc gagcgttcgcaggagttcctcaagtatatgcagtatcagggctacaagctgcacaagcct tcaaagggcggcgctgtggaggaaggaggcgccacccaggcggccgttgagctacgcttc tcatactctctgctggagaaacttatccagtatctggaccgagccaccatcaacatgaag ctgctgaagccatcgaccactttcagccgccgctcatccttcaagacggccacgcgggac atcaagttcttctcgaaggtggtcctccccctgatggagaagtacttctccacgcatcgc aattacttcattgccattgccacggcaacgaacaacattggagcagcctcgctcaaggag aaggaaatggtggcctcaatcttctgcaagctggcggctctgctgcgcaaccggttgagt gcctttgggccagatgtccgcatcacggtgcgttgcctccaggtgctagtaaaaggaatc gatgcccgcacgctgaccaagaactgcccggagttcattcgcacctccatgctgacgttc ttcaatcagacgtccgatgatctgggcaacacgatcctcaatctgcaggacggcaagtac agtcacctgaggggtacgcacctgaagacctccacgtcactgggctatgtcaaccaggtg gtactgcccgtgctcacggccatgtttgatcatttggccgcctgcgactatggcagcgat ctgctgctggacgagatccaggtggcctcgtataagattctggcggccctttatcacctg ggcacggatgccacgctgacgcacgaccgaaaatatctaaagacggagatcgagcgacat cgccccgctctaggctcgtgcctgggagcctacagctcctgcttcccggtggcctacctg gagccgcatctgaacaagcacaaccagtactcgctgctcaaccgcattgcggatcactcg ctggaggcgcaggacatcatggtgaagatggagagctgcatgcccaatttagagaccatt ctcgccgaggtggaccagttcgtggagtcggacaagacatacaacgatgcaccgcacatt atcgacgtgatcctgccgctgctttgcgcttatctgcccttctggtggtctcagggcccg gataacgtgagcccgaccagcggcaatcacgtgaccatggtcaccgctgaccacatgaat ccgctgctccgcaatgttctaaagatgatcaagaagaacattggcaacgacaacgcaccg tggatgacaaggattgctgcatacacgcagcagatcatcatcaatacgtcggaggagctg ctcaaggatccgttcctgccgctggccgagcgggtgaagaagcggactgagaatatgctc cataaagaagacagcatgcgaggcttcatcaagtcggccacggacgacacctcacaggtg gaaacgcagctacaggaggattggaacctgctggtgcgcgacatctactctttctatccg ctgctgatcaagtacgtggatttgcagcgcaatcattggctaaaggacaacatacccgag gccgaggagttgtacaaccatgtggcggagattttcaatatttggtcgaagagccagtac ttcctcaaggaggagcagaactttatctcggccaacgagatcgacaacatggccctgatt atgcccacggccacgcgcagatctgccatctctgagggtgtccctgccgttggcggcaag gtaaagaagaaaaagaagaaccgcgacaagaagcgcgacaaggacaaggaggtgcaggcc agtctcatggtggcctgcctgaagcgtctcctacccgtgggcctgaacctgttcgctggc cgggagcaggagctggtgcagcactgcaaggatcgctacctgaagaagatgcccgagtac gacgtgatcgagttcgcccgcatgcagctgaccctgcccgacaagctggacccctccgac gagatgtcctggcagcactacctgtactccaagctgggcaagacggaggagccggtggac gagcaggcgctggagaaggccaatgtcaatgccaacgagaagggcaaggacaagacccag gagacggtggaccgcatcgtggccatggccaaggttctgtttggcctgcacatgatcgac catccacaacagcagagcaaaaatgtctacaggagcgttgtgtcgatccaaaggaagcgt gccgttatcgcatgcttccgtcagacatcgctacattctctacccagacatcgggcttgc aacatttttgcccgctcctactacgagcagtggctgcaggaggagaacgtgggccaggag gtgatggtcgaggatctgacgcagactttcgaggattccgaaaagtccaagaaggacgag gaggagacggacagcaagccggatccgctcacccagctggtgaccaccttctgccgcggc gccatgaccgagcgcagtggtgccctccaggaggatttgctctacatgtcctacgcccag attgcggccaagtcctgcggcgaggaggaggaggagggcggcgacgaggagggcggtgag ggtggcgaagagggcgaaggcaccagtatccatgaacaagagatggagaagcaaaagctg ctcttccaccaggcgcgcctctcgaatcgtggcgttgccgaaatggtgctgttgcacatt tccgcctccaaaggtataccttcggagatggtaatgacgacactcaatctcggcatcgcc attctccgcggcggcaacatcgacatccagatgggaatgttgaatcacctcaaggagaag aaggacgtcgggttcttcacctcgattgccggactgatgaactcctgcagcgtgctcgac ctggacgccttcgagcgtaacaccaaagcagaggagtatattccgagtgcgggtgcaggt cttggtgtaggttccgagggtgctgccggcgagaagaacatgcacgatgcggagttcacc tgtgccctgttccggttcatccagctcacctgtgagggtcacaatttggagtggcagaac tacttgaggacccaggccggcaacaccaccactgttaacgtagtcatctgcacggtggat tatctgctgcgactgcaggagtccattatggacttctactggcattactccagcaaggag atcattgatcccgcgggcaaggccaactttttcaaggccatcggagtggccagccaggta ttcaacacccttactgaggtcatccagggtccttgtaccctcaatcagcaggcattggcc cactccaggttgtgggatgccgttggaggattcctgttcctgttctcgcacatgcaggac aagctttcgaagcactccagccaagtggatctgctcaaagagctgctcaatctgcagaag gacatgatcaccatgatgttgtctatgctggaaggaaatgttgtgaatggcaccattggc aagcagatggtggacactcttgtggagtccgcctccaatgtggagcttatcctcaagtac tttgacatgttcctcaaactggctgacctcatcgaatcgcccagcttccatgagatcgac atgaagaacgagggctgggtaacgcccaaggacttcagggagaagatggagcaatccaag aactacacgccggaagaaatggatttccttttggcctgctgcgagcgcaaccacgagggc aaaatcgactaccgggccttcgtggagcgcttccacgaaccatcaaaggagatcggtttc aacctggctgtgctgctgaccaacctcagcgaacacatgcccaacgagccgcgcttggcg cgcttcctggagaccgccggctcggtgctaaattatttcgagcccttcctgggccgcatc gagattctcggcagctccaagcgcatcgagcgcgtctacttcgaaatcaaggactcaaac atcgagcagtgggagaagccgcagattcgcgaatccaagcgcgccttcttctactccatc gtcaccgagggcggtgacaaggagaagctggaagcctttgtcaacttctgtgaggacgcc atctttgagatgacccatgcctccggcctgatggccaccgatgacggtggcggcaatgtg aaacgagacaccgcctatagttcctacatgagcgaggaggaggaggagcgtgccgcccga gatcccatccgacgcactatcaccgccgtcaaggagggcctcaagttcggcgtgcacatg ctcagtccggcgaacattaagcaccagatcggcgtcatgcagaccaagtccatcccagag ctgatcgtcggcttcttcaagatcatcttctacatcttttactacaccggatatgcgcac ttctgcgtggtgcgttatatattcggcatcctgctgaacctgatgcgtggacctgctccg gagcaggaggaggagccagttgtagaggaggaaacgtttggaagagccctgccaccgcta ccgcttgaggagccgccgggcacggtacaagcttttggcctggacatcaacaaggaggag aacggtatgtacaaggtggtggtgcacgagtctccggccaattcctcaatggaggagggc ggcgagtcgagtcccgaggacggtacggccatcaccggtgaactggcagagggcgagcca caccaggagccaatctccattgtggatctgctgggtggtgaggcagccaagaaggcggcc caggagcgtcaggaggcacagaaggcccaagaggcggcaatggcctccatcgaggcggag gccaagaaatcatcggccgcgccacaggagacgcctgccgtccaccagatagacttctcg cagtacacccatcgggccgtcagcttcctggccaggaacttctacaacctcaagtacgtg gccctggtgctggccttcagcatcaacttcatgctcctcttctacaaggtcacctcgttt gccgaggaaggcgaaagctccggcgaggaggaactcatcctgggctctggctcaggtgca ggtgcggacatcacgggctccggctttgggggatcaggagacggtgggtcgggcgatggg gaaatggaagacgagataccagaacttgtgcacgtggacgaggacttcttctacatggaa cacgtattacgcatggccgcctgtctgcactcgctcgtctccctggccatgctgatcgcc tactatcacctcaaggtacctctggccatcttcaagcgcgaaaaggaaattgcccgccga ctggagttcgatggcctgttcattgcggagcaaccggaggatgacgacttcaaatcgcac tgggacaaactggtgatatctgcaaagagcttcccggtcaactattgggacaagttcgta aagaagaaggtgcgacaaaagtacagcgagacctatgacttcgactccatctccaacctg ctgggcatggaaaagagcgccttcaccgcacaggagagcgaggagacgggcatcttcaag tacatcatgaacatcgattggcgctaccaggtgtggaaggccggagtgaccttcacggac aacgctttcctctactcgctgtggtactttagcttctcggtgatgggcaacttcaataac ttcttctttgccgcccatctgctggatgtggccgtgggcttcaagacgctgcgcaccatc ctgcagtccgtcacccacaacggcaaacaacttgtcctgaccgtgatgctcctgaccatt attgtatacatctacacagtgattgcctttaacttcttcaggaagttctacattcaggaa gaggacgaggaggtggacaagaagtgtcacgacatgttgacttgcttcgtcttccatctg tacaagggcgtgagagcgggcggtggcataggcgacgagatcggtgatccggatggcgat gactatgaggtctatcgcatcatcttcgacatcacgttcttcttcttcgtgatcattatc ctgctggccatcatccagggtctgattatcgacgccttcggcgagctgcgtgaccagctg gagtcggtgaaggacaacatggagtccaattgcttcatatgcggaatgggcaaggacttc ttcgacatagtaccgcacggcttcgacacgcacgtccagaaggagcataacctagccaat tacatgttcttcctgatgcatttgattaacaagccggacacggagtacaccggccaggag acgtacgtgtggaacatgtaccagcagcgcagctgggacttcttcccggtgggtgactgc ttccgcaagcagtacgaggacgagctatccggcggaggcggcggcggctaa

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