Dolosigranulum savutiense: VUQ06_02035
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Entry
VUQ06_02035 CDS
T10362
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dst Dolosigranulum savutiense
Pathway
dst00300
Lysine biosynthesis
dst00550
Peptidoglycan biosynthesis
dst01100
Metabolic pathways
dst01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dst00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
VUQ06_02035 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
VUQ06_02035 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
VUQ06_02035 (murF)
Enzymes [BR:
dst01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
VUQ06_02035 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
XBC50018
UniProt:
A0AB74U3W9
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Position
complement(469562..470938)
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AA seq
458 aa
AA seq
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MIEQTLATIAKAVAGRVYPNDAGDVKVQGVQFDSRQIESGNLFVPLVAERDGHDFTSSAI
EKGAVATLWSKDAAAVPAGLPAILVDDTLAAYQALAEWYLQEVSPTVVAITGSNGKTTTK
DMTAAVVSTQYKTHKTEANYNNHLGVPMTILSMAPETDVIILEMGMDHPGDIHDLSILAQ
PDIGVITMIGESHLEFFGSREKIAEAKLELLDGFKGSSVLVTTGDEPLLAEALEKTQSCS
FGLGDGNDLRARDIVNLKHTTEFIVAGHEELTVTIPVPGRHNVHNALAALSVGLQLEIPL
AVGAAGLATFQLTKNRLEWIAGKQHSQILNDAYNASPSSMKAVLGYMGALEHDGRKLVVL
GDMRELGEQSQLLHESLATSIQLGAFDEVYLYGDQMRALYEKLASKLSANHLHYVKEGTA
TLAAQIEAELQPGDAVLVKSSFGTNLLDVVARLKESDV
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgatagaacagacgctagcaacgatagctaaagcggtcgctggacgtgtttacccgaat
gatgctggagatgttaaggttcagggggtgcagttcgattctcgacaaatagagtccggg
aatttatttgttcctttagtcgctgaacgcgatggtcatgattttacgtcaagtgctatt
gagaagggggcagtcgctacgctttggagcaaggatgcagcagctgtgccggcaggactg
cccgctatattagtggatgatacgttggcagcttaccaagcattggctgagtggtatttg
caagaagtgagtccaacggtggtagctattactgggagcaacgggaagaccacaaccaaa
gatatgacagcggctgtggtctctacacagtacaaaacccataaaacagaggccaactat
aataatcacctaggagttccaatgactatcttgagtatggcaccagagacggatgttatt
attttagagatgggcatggatcatccgggagacattcatgacttatctatcttagctcag
ccagatattggtgttattacgatgattggtgaatcacacttagaattctttggctcaaga
gagaagattgccgaagctaagctggagttgctggatggctttaagggaagcagtgtattg
gtaacaacgggtgacgaaccgttattagcagaagcgcttgagaagacgcagagttgttct
tttgggctgggagacgggaatgatttgcgcgctagggatatagtaaatcttaaacatacg
actgagttcatcgtggcaggtcacgaggaattaacggtgactattccagttccaggtcga
cataatgttcataatgccttggctgctctgtcggttgggttgcaactggagattccctta
gcagtgggagcagctggattagctacattccaattgactaagaaccgcttagaatggata
gctgggaaacagcattcacaaatcttgaatgatgcttataatgcaagcccaagttcgatg
aaagctgtgttagggtatatgggagcactggaacatgatgggcggaagcttgtagtgtta
ggagatatgcgtgaattaggcgaacaatctcaattgttgcatgaatcactcgccacgtcc
attcaattaggggcattcgatgaagtctatctctatggtgatcagatgcgtgcattgtac
gagaagttagcgtcgaaattatcagccaaccacctccactatgttaaagaaggaacagct
acgttagcagcacagattgaagcggagttgcaaccgggagatgcggtattggtgaagtct
agtttcgggactaatttactcgatgtcgttgcgcgcttgaaagaatcagacgtatga
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