Dolosigranulum savutiense: VUQ06_07675
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Entry
VUQ06_07675 CDS
T10362
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
dst Dolosigranulum savutiense
Pathway
dst00270
Cysteine and methionine metabolism
dst00480
Glutathione metabolism
dst01100
Metabolic pathways
dst01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
dst00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
VUQ06_07675 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
VUQ06_07675 (gshAB)
Enzymes [BR:
dst01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
VUQ06_07675 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
ATPgrasp_ST
Dala_Dala_lig_C
GARS_A
Rimk_N
AICARFT_IMPCHas
Motif
Other DBs
NCBI-ProteinID:
XBC49356
UniProt:
A0AB74TQD4
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Position
1644095..1646386
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AA seq
763 aa
AA seq
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MKMQALITQNNLGREFQRCCLGIERESLRVQEDATLALTKVPSSIGPRASHPYLLTDFSE
SQPEFVTPPSCSCLDRTFDWLAALHDVYIQAMNTDEYLWPFSMPCLLPDEADIPIIDVPE
QGEIAYREYLAKHYGKKLQMISGIHFNFSFSEQFITRLFEEQTEYSELISFKNALYLKLT
RNFLRYHWLITYVYGASPVADESFYSGEKHGKTPPEQYVRSLRNSSYGYNNFSDVRVPLT
SVSEYSTVIQQLVKDKKISEEREYYGNARLKGHGKYTKDLMEQGIKYVEFRSIDVNPFDQ
FGLSREQAEFFRLFFMMLVWLDEDASEADIERGMTMNEQVASEHPFAVTTYQAEGLRLLE
KMIEVAEFVEANDKAQAEIAFVQSALMDPTKTYAAQIVHEIEKSSYIEFGQLLAQKYKGL
STAEPYRLRGFDDLEMSTQLLMSDAIERGIQVEFIDRQDQLLKLSVADHIEYVRNGNMTR
LDSTISHFLMSNKTATKRILAQAGFKVPGGAEYRSLTEAMANYPRFADKPTVIKPKSTNY
GVGISIFKQGMSESSYKEALEIALAEDETVLIEDYIAGTEYRFLVIGGVCRAVLLRQPAN
VIGDGKRTVAELIAAKNQDPLRGEEHRAPLTKIECGQIERMVLKEQGLTFESVPEKGQRV
LLRENTNISTGGDSIDMTDAVDPSYKRMAEAMARTIDVQITGIDLIIPDIHKPSTVNQPG
YTLIEMNYNPAMNMHTYVYEGEGRRVTQDVLNLLFPELPERSN
NT seq
2292 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgcaagcattaattacacagaataatttaggacgagaatttcagcggtgttgt
ttaggtattgaacgggagtctctccgggtacaggaagatgctacattagcacttacgaag
gttccttcctcaattggaccgcgagcaagtcatccttatttattgacggactttagtgag
tcacagcccgaatttgttacgccgccgagttgtagttgtttagaccggacatttgattgg
ttagcggcgcttcatgatgtgtatatccaagcaatgaatactgatgaatatttgtggcca
tttagtatgccgtgcttattaccggatgaagcagatattccaattattgatgtgccagag
caaggagagattgcgtatcgtgaatatttagctaagcattatggcaagaaacttcaaatg
attagtgggattcactttaatttttccttttctgagcagtttattacaagattgtttgaa
gaacagactgagtatagtgagttgatttcttttaagaatgcactttatctgaaattaacg
cgtaattttttgcgatatcattggctaataacctatgtgtacggtgcctcacctgtggca
gatgagtctttttattcaggggaaaagcatgggaagacaccaccggaacagtatgttaga
agcttacgtaatagctcatatggctacaataatttttctgatgtgcgagtgccgttaacg
tcggtatctgagtatagcacggtcattcagcagctggttaaagataaaaaaattagtgaa
gagcgtgaatattatggcaatgctcgtctgaagggacacggcaaatatacaaaagatctc
atggaacagggcattaaatatgtcgagttccgttcaattgatgtgaatccattcgatcag
ttcggcttatcgcgtgaacaagctgaatttttccgtctgttttttatgatgcttgtatgg
cttgatgaggatgcatctgaagcagacattgaacgtgggatgacaatgaatgaacaggtt
gcttcagagcatccttttgcagtaactacctatcaggctgaaggcttacgtttattggaa
aagatgatagaagtcgctgaatttgttgaagctaacgataaagcacaagctgagattgca
tttgttcaatcagctttaatggacccgactaaaacgtatgctgcccaaatagtacatgaa
atagaaaaaagttcgtatatagaatttggtcaattactggctcagaagtataaagggtta
tccacagcggaaccttatcgtctacgtgggtttgatgatttggaaatgtcaactcagtta
ctcatgagtgatgcgattgaacgaggaatccaggttgagtttattgatcgacaggatcaa
ctattgaaattatcggtagctgatcatatcgaatatgtgcgaaatggtaatatgactcgg
cttgactcaacaatcagtcatttcttaatgtcaaacaagacagcgactaaacgtattttg
gcccaagctggttttaaggttccaggtggtgctgagtatcgaagtctcacagaagctatg
gcaaattacccacgatttgctgacaagccaactgttatcaagcctaaatcaactaattac
ggtgtcgggatttcaatttttaaacaaggaatgtcagagagttcttataaggaagcatta
gaaattgctttagcagaagatgagacggttttaattgaagattatattgcgggtacggaa
tatcggtttcttgttatcggtggagtttgtcgggcggtattgttacggcaaccagctaat
gtaataggggatgggaaacgaacggttgccgagttaatagcagctaaaaatcaagatcca
ttacgtggcgaggaacatcgcgccccccttacaaaaattgagtgtggtcaaattgaacgc
atggtactgaaagaacaaggcttaacctttgaaagcgtaccggagaagggtcaacgtgtc
ttgttgcgagaaaatacaaacatctcaacgggtggagattcgattgatatgacagatgct
gtcgatccatcctataaacgaatggctgaagcaatggctcgaacaattgatgttcagata
acaggtattgacttaattattccggatattcacaagccttcaactgtcaatcagcccggt
tatacgttgattgagatgaattataacccagccatgaatatgcacacctatgtatacgaa
ggagaaggaagacgagtaactcaagatgtgttgaacttgttattcccggaattacccgag
cgcagtaactaa
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