KEGG   Dendrobates tinctorius (dyeing poison frog): 141082797
Entry
141082797         CDS       T11000                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
dtc  Dendrobates tinctorius (dyeing poison frog)
Pathway
dtc00562  Inositol phosphate metabolism
dtc01100  Metabolic pathways
dtc04020  Calcium signaling pathway
dtc04070  Phosphatidylinositol signaling system
dtc04081  Hormone signaling
dtc04082  Neuroactive ligand signaling
dtc04261  Adrenergic signaling in cardiomyocytes
dtc04270  Vascular smooth muscle contraction
dtc04310  Wnt signaling pathway
dtc04371  Apelin signaling pathway
dtc04540  Gap junction
dtc04621  NOD-like receptor signaling pathway
dtc04912  GnRH signaling pathway
dtc04916  Melanogenesis
Module
dtc_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dtc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    141082797 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    141082797 (PLCB2)
   04371 Apelin signaling pathway
    141082797 (PLCB2)
   04020 Calcium signaling pathway
    141082797 (PLCB2)
   04070 Phosphatidylinositol signaling system
    141082797 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    141082797 (PLCB2)
   04081 Hormone signaling
    141082797 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    141082797 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    141082797 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    141082797 (PLCB2)
   04916 Melanogenesis
    141082797 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    141082797 (PLCB2)
   04270 Vascular smooth muscle contraction
    141082797 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dtc04131]
    141082797 (PLCB2)
Enzymes [BR:dtc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     141082797 (PLCB2)
Membrane trafficking [BR:dtc04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    141082797 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    141082797 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2
Other DBs
NCBI-GeneID: 141082797
NCBI-ProteinID: XP_073422833
LinkDB
Position
Unknown
AA seq 1226 aa
MSMLTPILTHSEIKAYLSKGERFIKWDDETSTASPVILRVDLKGYYLYWTFQSKEIEFIE
LTSIRDTRYGKYAKIPKSPKLREVFNLDFPENNFLAKTLCIVTGPDMVDLTFHNFVSYKE
NVGKDWATDIMTYIKNPLLNNASRYSYYEKIHVKLTLQLNAEGKIPVRNIFQLFPADRKR
VEHALQCCHLSKGKNDAINPEDFPESVYRTFLMQLCPRPEIDEIFTSHHSKAKPYMTKDH
LTKFINQKQRDSRLNELLFPPAKIEQVQVLIEKYEPSAINKQRGQLSPEGMVWFLCGSEN
SIVSMDKLLVNQDMNQPLTHYFINSSHNTYLTAGQFSGISSPEMYRQTLLSGCRCVELDC
WKGKPPEEEPIITHGFTMTTEILFKDVIEAIAESAFKTSPYPVVLSFENHVDSAKQQAKM
AEYCRTLFGDMLLTDVLEKFPLKPGCPVPSPNDLQGKILIKNKKNQAFSSAEKKTQANDP
TDNQADEDAEKEGESEEVVEIVDEEQMKQMQSDEGTAGQEAMSYEEMSSLVNYVQPVKFE
SFEISAQKNQSYVISSFVETKAYDLMTKFPVQFVEYNKRQMSRIYPKGTRMDSSNYMPQM
FWNAGCQMVALNFQTMDLAMQQNMAIFEFNGSSGYILKHEFMRRTDKQFDPFTVDRIDVV
VANTLAITIISGQFLSDKSVKTYVEVELFGLPGDPKRKYKTKLTSTANSINPVWKEEPFM
FEKILMPEMASLRVAVFEEGGKFIGHRIIPIDVIRTGYHHICLRSESNMPLTMPSLFVYV
EVKDYVPDTWAELTHALSNPIKAFKATEKSIKMNNKTSFDEKSVNLQCNGMSGSIKLSNV
LLQNCTATKGSLSSGKVDSTNEAAELETTNQDDLQKHKGFMKLQKKHEKELKEQERKGMK
RREEILQKYTSAFSDLYTQTNKKKICKKTSKSLEDDYGSVWGAGEIPGKPDSKVVELKEK
MEQELMRQGEELHESIWKRKEQHSIEQAAKLLELAQEKQTTEMKVLKESTDSDTKQMKKK
LEMKRMERLETMSKNTMDKAAQERLKKEINNSHIQEVVQVLQMVSDKWGNQQQKLEEKQA
EGLQRIKEKREQTQKDLEQEYQGKIKNLEVEIPDAVHDCMAPYFPSEAKSLKKEPGNHVN
RWQFLFGKSDNVESSVTKTPEESDTQIDPSATEVEDKSLTGGSATEEPILRAALLCETSA
TDALPSGTPTASDVVGKTPSGEASKQ
NT seq 3681 nt   +upstreamnt  +downstreamnt
atgtcaatgctaactcctatccttacccactccgagatcaaagcctacctgtccaagggg
gagcgattcataaaatgggatgatgaaacgtctacagcttctccagttattctacgtgta
gacctgaagggttattacctgtactggactttccagagcaaagaaatagaatttatcgag
ctgaccagtatccgggacacacgatatggaaaatatgccaaaatccccaagagtccgaaa
ttgcgtgaagttttcaacctggactttccagaaaataatttcctggccaaaactctatgt
atcgttactgggccagacatggtggatcttacctttcataactttgtatcctacaaggaa
aatgtcggcaaggactgggctactgatattatgacatacatcaaaaaccctcttctaaac
aatgcttctcgctattcctattatgagaaaatacatgtaaaactcacacttcagttaaat
gcagaaggaaaaattcctgtacgcaatattttccagctgtttcctgccgacaggaagaga
gtagagcatgcattacaatgttgtcatctttcaaaggggaaaaatgatgccatcaatcca
gaggattttcccgagtccgtctacagaacattcctcatgcagctctgcccacggccagag
atagatgaaatcttcacatcccaccattctaaagccaaaccttacatgacgaaagatcat
ctcaccaagtttatcaaccagaagcagagagacagtcgtttaaatgaattgctctttcct
ccagcaaagatcgagcaagtacaagttctcatagaaaagtacgaacccagcgccatcaac
aagcagagagggcagctgtctccagaaggaatggtttggtttctctgtggctccgagaac
agtattgtgtcaatggacaagttacttgtgaatcaggacatgaaccaacctcttactcac
tactttatcaactcctctcataacacatacctcacagctggtcagttttctgggatctca
tcccctgaaatgtaccgtcagaccctgctctctggttgccgatgtgtggagctagactgc
tggaaggggaagccacccgaggaagaacccatcatcactcatggatttacaatgacgaca
gaaatccttttcaaggacgtcattgaagctatcgcagaatcggccttcaaaacgtctcct
tatccagtagtcttgtcgtttgaaaaccacgttgactctgccaagcaacaggcaaaaatg
gccgagtactgcagaacattatttggagacatgctactgactgatgttctggaaaagttt
ccactgaaacctggatgtccggtaccaagccccaatgacttgcaaggcaaaatcctgata
aaaaataagaagaaccaggccttttcatctgctgagaagaaaacccaagccaatgaccca
acagataatcaagctgacgaggatgcagagaaagaaggagaaagtgaggaggttgtcgaa
attgtggatgaagaacagatgaagcagatgcagtcagatgagggtactgctggtcaggag
gccatgtcttatgaagagatgtcaagtttagtcaactacgtccagcctgttaaatttgag
tcattcgaaatctctgcacaaaagaatcaaagctatgtaatttcttcatttgtggagact
aaagcctatgatctaatgaccaagttccccgtgcagttcgttgaatacaataagcggcaa
atgagtcgaatttatccaaagggaaccaggatggattcctctaattacatgccacaaatg
ttctggaatgcgggatgtcaaatggtggcgctcaacttccagactatggacctggcgatg
cagcagaacatggccatctttgagttcaatggcagcagtgggtacatactgaaacacgaa
tttatgaggcgcacggacaagcaatttgatccctttacagttgaccgtattgatgtggtt
gtggccaacacacttgcaattacaataatctcaggtcaattcctcagtgataaaagtgtg
aaaacttatgtagaagttgagctctttggattgccgggagatcccaagcgcaagtacaaa
acaaaattaacctctactgcaaactccatcaaccctgtatggaaagaagagccatttatg
tttgaaaagattctgatgccagaaatggcatctctacgagtcgcagtatttgaggaagga
gggaaatttattggtcatcggatcataccgattgatgtgattagaacaggctaccatcat
atatgtcttcggagtgaaagcaacatgccactgacaatgccatctctgtttgtctatgtg
gaggtgaaagactacgtgccggatacatgggcagaacttactcatgctctctcaaacccc
atcaaagcttttaaagccactgagaaatcaataaagatgaacaacaagacgtcatttgat
gagaaatctgtgaatcttcagtgcaatgggatgagcggctctataaaactgtccaacgtg
ttgctgcagaattgtacagcaactaaaggttcgttgagcagtggaaaagtggattctaca
aatgaagcagcagaactagaaaccacaaatcaggacgacttacaaaaacacaaaggtttt
atgaaacttcagaagaagcacgagaaagagctgaaggagcaggagcgcaaaggaatgaaa
cgtagagaagagatccttcaaaagtataccagtgccttcagtgacctgtacacacagacc
aacaagaagaaaatctgcaagaaaaccagcaaaagtctggaagatgactatggctcagtg
tggggtgctggtgaaatcccaggtaaaccagattctaaggtggtggaattgaaagagaag
atggagcaggaactgatgcgccagggagaggagctgcatgagagtatctggaaaaggaaa
gaacaacactccattgaacaagctgccaaactgctggagttagcccaagaaaagcaaaca
acggaaatgaaagtcctgaaggaatcgacagacagtgacactaaacagatgaagaagaag
ctggagatgaagaggatggaaagactggaaaccatgagcaagaatacgatggataaagct
gctcaggagaggttaaaaaaggaaataaataactcacacattcaagaagtggtgcaggtt
ctacaaatggtatctgataaatggggcaatcagcaacagaaactagaagaaaaacaggcc
gaaggactgcagagaatcaaagagaaaagagagcagactcaaaaagaccttgaacaggaa
taccaggggaagattaagaacctagaagtggaaataccagatgcggtacatgattgcatg
gcaccgtattttccctcagaagccaaatctttgaaaaaagagccagggaaccatgtaaat
aggtggcaatttctatttggaaaatctgacaatgtagaatcttcggttacaaaaactcct
gaggaatcagatactcaaattgacccatctgcaacagaagtagaagataaatctttaact
ggtggttctgccacggaagaaccaattttaagagctgctttgttgtgcgagacatctgca
accgatgcattaccgagtggcactccaacagcttcagacgtagtaggaaagactccttca
ggggaagcgtccaaacaataa

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