Dendrobates tinctorius (dyeing poison frog): 141085190
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Entry
141085190 CDS
T11000
Symbol
KMT2B
Name
(RefSeq) histone-lysine N-methyltransferase 2B isoform X1
KO
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
Organism
dtc Dendrobates tinctorius (dyeing poison frog)
Pathway
dtc00310
Lysine degradation
dtc01100
Metabolic pathways
Brite
Enzymes [BR:
dtc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
141085190 (KMT2B)
Transcription factors [BR:
dtc03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
141085190 (KMT2B)
Chromosome and associated proteins [BR:
dtc03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
141085190 (KMT2B)
HMT complexes
MLL3/MLL4 complex
141085190 (KMT2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SET
FYRC
FYRN
PHD
zf-CXXC
zf-HC5HC2H
zf-HC5HC2H_2
PHD_2
Bromodomain
PHD_5
Motif
Other DBs
NCBI-GeneID:
141085190
NCBI-ProteinID:
XP_073426509
LinkDB
All DBs
Position
Unknown
AA seq
2957 aa
AA seq
DB search
MAAAASAGPGASGSVRGRFPGRPWVGRSGNRADRVRVPFTSTGRVAAEIVDPVHLRILEL
HLNMQRLAGACGRDSDSAEGEFEGFSEEEFKQSALRLALRSNKGPRSKSLSHCAPSVKSC
STPASPASPPAPCVTREGPTTPVRQHTSLALHNIKKSFTPEKIVRVHLTQLDPSLYSLNS
PTILCSAKETPKSPVSHSVSSLAPCIFFSPERNPHPNDLTKPPDCSTVPPVHNRCRKSNG
KQTGSRHRTQTAPRPCKASVKEVDRFPDASAGESNSTEPPEGCSSDPADANMKTSISSTW
KTLDETSAPVVTSSGEPRSQVTCKSKRGKVREQRSEGAPEAKEVTKRRRLRSREVPKVKW
KLRGSCRQERQSEEAKVETPTYEDDSKEEEQEKLLIDTDSLTTDCKQSSLSSAEETAPTR
EETTDQSKNDGQDGTETSGHEEDKAANDKEEITKSKEKGPELEAEETPPESSAMESTLIA
APRNEQSSLGDKSEPPLPILKIKILRSQKEKLKRALKAERMAQRRLMIKMMQAEAKVESK
PESPAKVETPTNDDGGFLKPAASGRPSRVIKMPRRFIDDSEPPAAENPTKKVQSKPLLTM
AELEKQVLSDTHLPPSDPRFSLFNEDDHLNSLPPTLPNTDCPQIVSSTSAAPSESVRKNI
LRAPTFCWRSSNVSELQEAPLSTQPLFRLQSSTSPEDPLKTSTPASTSSPPSSSVPPKVE
SAKRSPLLRAPQFTPSAAHLKIYQSVSLQDTEATTSRLQQSDHSSTTAVTSSPEVLVSAL
TKPSDLQSSGRRANHLAFPLFVDSLSGNMVVNLDKTEAVDASSLKSEKPSGNLQQNDPLD
ASSKALEIGAMTLHNAQAAGRKVVVKAHLTSGVGSRENAATFPPNEISLSGTDKKVISLL
EKAKIQLFKIDKQKNVELAADSSQGDNGTTSPAAQGQDSPLQGPRIKHVCRHPAVALGQP
RAMIPEDIPRLSALPLCEREITVTSAAPEDDSSASDETITVVKSKPAKQPPARRPKALSR
AKFRMTRCGECKGCTVVNDCGTCINCLDKTKFGGPNTKKQCCVYKRCDVIEARRLQRLSH
KGRKAIRHLPPTRDSASESDDYITDSLRNEDTEASDRLEVGQTTQRKSTRRCVKQRPCYD
LFPDSEESDYDPSPSVPRHKQRRESESNNVISRGKKSVSSHVTDLLPQDSEEQSKPRRTP
QQPLILRARSGPKPDSMLNGSSTKIKSSDGTHRLRVDFKEDCDLQNVWLMGGLSILTSVP
ITPTHVCLLCASRGHHQFLYCQVCCEPFHTFCLEESERPLPEQEDGWCCQRCKFCNVCGR
KGKAKKPLLECELCQTNYHINCLGPRYPVNQPRSRKGWLCSSCIRCKSCGASPAVNADME
LAEGGNLCTECSSLYNKGNFCPICNRCYEENDYESKMIQCVKCLKWVHSKCEGLSDEGYE
ILSNLPDSVVYTCPPCLGDTSPIWREAMLSELTAGLHEILQELMTAKISTPLMQCVQCKV
GDNQGQCHHNPCDLESMSHLLEEGYYNSIAMFNDDLVWIIQQTMKSGKLDEDGEAVKTLY
IKLMEKSFTWFNVEDSKYWEKNHKSGNNGLLPHAVVPPYPDHTYAHWREREDGSQSNGIK
PQPVSPQKVRKEIGMELDLEKDTRQCALCPKYGDDNPKDAGRLLYIGQNEWTHINCAIWS
AEVFEEDDGSLKNVHAAVARGRQLRCEHCMKIGATVGCCLSTCQSNFHFMCARATRCSFQ
DDKKMFCQKHTSLLDRTTVAADSFDVLRRVYVDFDGINFRRKFLQGLETEDIHMMIGSMK
IDSLGMLSDLSVSEGKIFPVGYQCSRLYWSTQNARRRCWYKCRVVEHRPKEGDLPPEGLD
GPEDNRTIIHSPGHVPDNCPSWGQHSHAEKVSVSPSTPERTPVSRPPPSEPITSAVAPRS
FCGARMKNPNFSPTRRPLGGSSRPLPSPGSTTSSPLSHHILKVSDPDVTPHRRSRRPPPP
SPRTTRQSSVLLPNSPPSSSSVPAIRRSSSESEIPLPTGVASEVGTGPLQCRIPLIAGSE
ALVDESEGGSSTEEEVGDQYYGLTRTVVSHEPLSPLMMSATSGHIEQLDGIHDSTDSEDT
SQSRNDPLGSGKTPTHLPSDLVEFVLKAAGVSGTGGQTAVQQEVSTPAATSSAIILNGIT
APSLSNGTDCVKQGPPPLRDPPQVQRVCRPLLAMPNNGPLCLTIEPASGLRNNSGSNIIS
CNKPTGPLVINVAGSSSDVAGNAPLLQDLTKSDCVTITRVAPARPSKVAPKITNKVPIPC
LPQPAAAKLPPPVQPPNTNLGTVLLQTAPAPTWTLRVVPMLNLLQGNGQLTLGPQNMMAP
TITGISQTCLLQGLSMNGGLLSVAPTPQGQPQPQLQLPLLPPAQPQPQVQLPRLPPAQPQ
PQVQLPRLPPAQPQPQVQLPRLPPAQPQPQVQLPRLPPAQPQPQVQLPRLPPAQPQPQVQ
LPRLPPAQPQPQVQLPRLPPAQLQVQLPRLPPAQPQVQLPLLQPAPPKPVQVPHVCMKRV
AIGAASTSASKKLKLDLSDKLKLPNSQTLTQSVVMNLNCAFEKTRNTRPKRKMSEAVVQE
IVDLDLLDDEDPGMNMNGLLLDLTVDVKTELPMSESARESPVSDHVEDFSPNFDNFEDRF
LEEKENLFLKRGRPHLRFEIISEDGFYTQSDSAEGAWRRVVEKVQEARGVGRLRQLSFSG
LSGSRMLGVQHDAVLFLLEQLIGAERCRGYKFLFHPQEVEEEELLINTSGCARSEFYVRK
STFDMFNFLASQHRNLPELYALEEEEEEVQLKSTRRATSLDLPMAMRFRHLKKTSKEAVG
VYRSAIHGRGLFCKRNIDAGEMVIEYSGNVIRAVLTDKREKYYDSKGIGCYMFRIDDFDV
VDATMHGNAARFINHSCEPNCYSRVIHVEGQKHIVIFALRSIYRGEELTYDYKFPIEDAS
SKLHCNCGAKKCRRFLN
NT seq
8874 nt
NT seq
+upstream
nt +downstream
nt
atggcggctgcggcctcggctggtcccggagcctcgggctcggttcggggccgctttccc
ggccggccgtgggtgggaaggagcgggaaccgggcggacagagttcgggtgccgtttacc
agcactgggcgagtggcggcggagatcgtagaccccgttcacctccggatcctcgaactc
cacctgaacatgcagcgcctggcgggggcctgcggccgggacagtgacagcgccgagggg
gagtttgaggggttcagcgaggaggagttcaagcagagtgctctgcgccttgccctgcgc
tcaaataaaggtccaagatctaaatccttgtcccactgtgctccatctgtgaagtcttgc
tccacgccagcgagtcctgccagtccccctgcaccatgtgtgacgcgagagggccccaca
acgccggtcaggcagcacaccagcctggcactgcacaatattaagaagagtttcacgccc
gagaagatcgtacgggtgcatctgacacaactggacccctctctgtatagtctgaattct
cctactatactgtgttctgcgaaggagacccccaaatcccccgtcagtcatagtgtttcc
tctttagctccctgcattttcttctcccctgaaagaaatccacatcccaatgatctcact
aagccaccagattgctccactgttcctcctgtccacaacaggtgtcggaagagcaacgga
aagcagaccggatctagacaccggactcagacggcaccacgtccatgtaaagcaagcgtc
aaagaagtagacagattccccgatgcatctgctggggagagtaatagcaccgaaccccct
gaaggttgctcctcagatccggcagatgccaatatgaagacgtcgatttcctccacttgg
aagactctggatgagacatctgcacccgttgtcaccagttcaggagaaccaagaagccag
gtaacttgtaaatccaagagaggaaaggtcagagaacagaggtccgaaggggcaccagag
gccaaagaggtaacaaaacggagaagactgaggagccgtgaagtccccaaggtgaagtgg
aagctgcgcggaagttgtcgacaggaaaggcaatcggaagaagccaaggtagaaacgcca
acgtatgaagacgacagtaaggaggaagaacaagagaaactactgatcgacactgattct
ctaacaactgactgtaagcagtcttctttgtcctctgcagaagaaaccgcacctacaagg
gaagaaaccactgatcaatcaaagaacgatggccaagatggcacagaaacctcaggccat
gaagaagacaaagctgccaacgataaggaagagattaccaagtccaaggagaaaggtcct
gaattggaggctgaagagactcctccagagtcatcagcgatggagtcgactctgattgca
gccccacggaacgaacagagcagtttaggtgacaaatctgagccgcctctcccaatatta
aagattaagattctgcgaagtcagaaggaaaagttgaagcgagcactgaaggcggagcgc
atggctcagcgaaggcttatgattaagatgatgcaagcagaggccaaggtcgagtctaaa
ccagaatctcctgccaaagttgagacccccactaatgacgacgggggcttcctcaagccg
gcagcgagcggcagaccttcccgcgtcattaaaatgcctcgcagattcatagacgattcg
gagccaccggctgctgagaacccaactaagaaggtccagtccaagccgctcctcaccatg
gctgagctggagaagcaggtgctctccgacactcatcttcctccttctgaccctcggttt
agtctttttaacgaagacgaccacctgaactctctacctccaacgttgcccaacactgac
tgcccccagatcgtctcctcgacttccgccgctccttctgaaagcgttcgcaaaaatatc
ctccgagcgccaacattttgctggcggtcgtccaacgtctcggagcttcaggaggcgccg
ttatctactcaacctctctttcgtctgcaatcttcaacctctcccgaggaccccttaaag
accagcacgcccgcttcaacgtcttcccctccttcatccagcgttcctcccaaagtagag
tctgccaagcgttctcctctcctccgcgctcctcagtttacacccagcgccgcgcacctg
aagatttaccagtctgtctccctccaagacacggaggccaccacgagccgcctgcagcag
agcgaccacagttccactaccgcagtcacctcttctccagaagtcctggtgtcggctctg
actaaacctagtgatttgcagtcttcggggaggagagcgaaccatttggctttccctctg
tttgtggattccctttctggcaacatggtggtgaacctggacaagaccgaagctgtagat
gcctcaagtttgaaatcggagaagccgagcggcaacctgcagcagaatgacccactggat
gcatccagcaaagccctggagattggagccatgactctgcacaatgcccaggccgcaggg
cgcaaggtggtggtgaaggcccatctgacgtccggtgtggggtctcgggaaaacgccgcc
actttcccacccaacgaaattagcctctctggcaccgacaagaaggtcatcagcctcctg
gaaaaggccaagatacaactcttcaagatagacaagcagaagaacgtggaactggctgcg
gattcgtctcagggtgataatggcacaacgtctccagctgctcagggccaggattcccct
ctgcaaggaccccgcatcaagcacgtgtgcagacaccctgccgtggccctggggcagccc
cgcgccatgattcccgaggacatcccgcggctcagtgccctgccgctgtgtgagagggag
atcactgtgacctccgcggctccagaagacgactcctccgcctccgatgagaccatcacc
gtcgtgaaatccaagccagcgaagcagccgcccgcgcgcagacccaaggccttgtccaga
gccaagttccgcatgacccgatgcggcgagtgcaagggctgcacagtggtgaacgactgt
ggcacctgcatcaactgcctggacaaaaccaaatttggcggccccaatactaagaagcaa
tgctgcgtttacaagagatgcgacgtgattgaagcccgacggctgcagaggctctcacac
aaaggacggaaagcgatccgacacctcccgccgacccgcgacagcgcctccgaatcggac
gactacatcaccgactccctccgcaacgaagacactgaagcctccgaccgcttggaagtt
ggacagacgacccagcgcaaatctacccgccgctgtgtgaagcagcgcccctgctacgac
ctcttccccgactccgaagaatcagactacgacccgagccccagcgtcccccgccacaaa
cagagacgggagtctgagagtaacaacgtgatttctaggggaaaaaaatctgtttcttct
catgtcacagatttgcttccccaggactcggaggagcagagtaaaccccgcagaaccccg
cagcagcccctgatcctccgagccaggtccgggccgaagccggactctatgctgaatgga
tcatcaacgaagatcaagtcttctgatggaacgcatcgcctgcgcgtggacttcaaggag
gactgtgacttgcagaacgtgtggctgatggggggactcagcatcctgacctctgtgccc
ataactccgacacacgtgtgcctgctgtgtgcaagccgcgggcatcaccagttcttgtac
tgtcaggtgtgctgtgaacctttccacacattctgcctggaggagtccgagcggccttta
cccgagcaggaggacggctggtgctgccaacgatgcaagttctgcaatgtgtgcggacgc
aaggggaaggctaaaaagcctttactggagtgtgaactgtgtcagacaaattatcacatt
aactgtttgggtccaaggtaccctgtcaaccaaccgcgcagcaggaaaggctggctctgc
tcatcctgcatccgttgtaagagctgcggagcatctcctgctgtgaacgccgatatggaa
ctagcagaaggtggtaacctgtgcactgaatgctccagcctgtataataaaggaaatttc
tgcccaatctgcaatcgctgctacgaagaaaatgactatgagagtaaaatgatacagtgc
gttaaatgtttgaagtgggtgcactccaagtgtgagggcctctccgatgagggatacgag
atcctgtctaacctgccggacagcgtggtctacacctgccccccgtgcctgggcgacacc
agcccaatatggcgggaggccatgctctccgagctcacagcaggtctccatgaaattctg
caggaattaatgacagccaagatttccaccccattgatgcagtgcgtgcagtgtaaagtc
ggagacaaccagggacagtgtcaccataatccctgtgacctggagtctatgagccacctg
ctagaggaagggtactacaactccatagccatgttcaacgatgacttggtgtggattatc
caacaaaccatgaaaagcggcaaattggatgaagacggggaagctgtgaaaaccttgtat
atcaagctgatggagaaaagttttacttggtttaatgtcgaggactctaaatattgggag
aaaaaccacaaatctggaaacaatgggctccttcctcacgccgtggtgcccccctatccg
gatcatacttatgcccactggcgggagagagaagatggctcccagagcaatggcatcaag
ccgcagccagtatcccctcagaaagtgaggaaagaaattgggatggagctagatctggag
aaagacactcggcagtgcgctctgtgcccgaagtacggggacgacaaccccaaggacgcc
gggagactcctttatattggccagaatgagtggactcacatcaactgcgccatctggtcg
gccgaggtgttcgaggaggatgacggctccctgaaaaacgtgcatgccgccgtggcgaga
ggacggcagctgcgttgcgagcactgtatgaagattggcgccacggttggctgctgcctg
tccacgtgccagagtaatttccacttcatgtgcgcacgagcaacgcgttgcagcttccag
gacgacaagaagatgttctgtcaaaaacacacgagtctgctggacaggacgacggtcgcc
gccgactcctttgacgtgctgcgcagagtctatgtggactttgacggaatcaactttagg
aggaagtttcttcagggtctggagacggaggacatccacatgatgatcggctccatgaag
atagactcgctgggcatgctttcagatttatctgtgtctgaagggaagattttccccgtc
ggttaccaatgttctcgcctgtactggagcacgcagaacgcccggcggcgctgctggtac
aaatgcagggtggtcgagcatcggcctaaagagggggatcttcctccggaaggactggac
ggcccagaggataacaggaccatcatccacagcccaggacacgtcccagataactgcccc
agctggggacagcacagtcatgctgagaaggtctcagtcagtccttccaccccggagaga
accccggtttctcgaccgcccccttcagagcccatcacctccgcagttgccccccgatcc
ttctgcggtgcacggatgaagaatccaaacttctctccaacacggcggccgctcggaggc
tcttcccgcccgctgccgtccccagggagtacaacgtcttccccattatcccaccacatc
ctcaaggtcagcgatcctgatgtgacgcctcaccgtaggtccagacgccccccgccgccg
tcacccagaaccacccgtcagtcttctgtgctgctccccaactcacccccctccagctcc
tctgtgccggctatccgccggtcatcctctgagagcgagattccgctgccgacgggcgtc
gcgtctgaggtgggcaccggtccgctgcagtgcagaatcccgctgattgcaggctccgag
gcactggtggatgaatctgagggcggcagcagcacagaggaggaagtgggcgaccagtac
tatgggctgactcggacggtggtgtcccatgaacctttaagcccactgatgatgtctgcg
acgtccggacatattgaacagctggacggcatccacgacagtacggacagcgaggacacg
tcacaaagccgcaacgacccactgggcagcggtaagacccccacccacctgccttcagat
ttagtggagtttgtgctgaaagcagcaggagtgtctgggacaggagggcagactgcggtg
cagcaggaggtgtccaccccggcggccaccagttccgccatcattttgaacgggattaca
gctccttcactgtccaatggcacggactgtgtaaagcagggaccaccgccgctcagggac
cccccacaagtgcagagagtgtgtcgtccactactggccatgcccaataatggcccgctg
tgcctgaccatcgaaccggcatccggcctccgaaacaattctggatcgaacattatatca
tgcaataagccgacgggccccctggtgataaacgtggcgggcagcagctcggacgtggca
ggaaatgctccgctgctacaggaccttactaaatccgattgtgtcacaatcacacgggtg
gcccctgcccggcccagtaaggtggccccgaagatcacaaacaaggttcccatcccttgt
cttcctcagccggccgcagccaagctcccacctccggtgcagcccccaaacaccaacctt
ggcaccgttttattacagacggcccctgcacccacatggacgctgcgagttgttccaatg
ttaaacctgttgcaggggaacgggcagctcaccctggggccacagaacatgatggccccc
accatcactggcatctctcagacgtgtcttctgcagggtctctctatgaatgggggacta
ctcagtgttgctccaacccctcaaggtcaaccccagccacagttacaactgcctcttctc
ccgccggcccaaccccagccgcaggtacagctgcctcgcctcccgccggcccaaccccag
ccgcaggtacagctgcctcgcctcccgccggcccaaccccagccacaggtacagctgcct
cgcctccctccggcccaaccccagccgcaggtacagctgcctcgcctcccgccggcccaa
ccccagccgcaggtacagctgcctcgcctcccgccggcccaaccccagccgcaggtacag
ctgcctcgcctcccgccggcccaaccccagccgcaggtacagctgcctcgcctcccgccg
gcccagctgcaggtacagctgcctcgcctcccgccggcccagccgcaggtacagctgcct
ctcctacagccggccccccctaagccagtccaagtaccacacgtctgcatgaagagagtg
gccatcggtgctgccagcacatctgccagcaagaaactcaaactggacttgtctgataaa
ctgaaattaccaaactcgcagacattaacgcagtctgtggtcatgaatttaaactgcgca
tttgagaagacgagaaacacaagaccaaagcgtaagatgagtgaagcggttgtgcaggag
attgtggacttagacttgctggatgatgaggatcccgggatgaacatgaacgggcttctt
cttgacctcactgtggatgtgaaaaccgaattaccaatgtcagaatcggcaagagagtct
ccggtctccgatcacgtggaagatttctcccctaattttgacaactttgaggaccgattt
ctggaggagaaggagaatctgttcctgaaaagaggcagaccgcacctgcgctttgagatc
atcagcgaggacggcttctacacccagtccgacagcgctgaaggtgcatggaggagagtg
gtggagaaggtgcaggaggcgcgaggtgtcgggaggctccggcagctgtccttttccggt
ctgagcggatcacggatgctgggagttcagcacgacgctgtcctcttcctcctggagcag
ctcatcggagccgagcgctgccgcgggtataagttccttttccatccgcaggaggtagag
gaggaagagctgctgatcaacacgtctgggtgcgcgcggagcgagttctatgttcggaag
agcaccttcgacatgttcaatttcctggcgtcgcagcaccgcaacctgccggagctgtac
gcactcgaggaagaggaggaagaggtgcagctgaagtccaccaggcgagcgacaagtctg
gatctccccatggcgatgaggttcaggcacttgaagaaaacgtccaaagaagcggtgggg
gtctacaggtctgccattcacggccgggggctgttttgtaaaaggaacatcgatgctggc
gaaatggtcatcgaatattccggcaacgtgatccgtgccgtcctgactgacaagcgggag
aaatactacgatagcaagggcatcggctgttacatgttccgtatcgatgactttgatgtg
gtggacgccacgatgcacgggaatgcagcgagattcatcaaccactcgtgtgagcccaac
tgctactccagggtgatccacgtggaaggccagaaacacattgtcatcttcgccctccgg
agcatttaccgcggcgaggagctgacctacgactacaagttccccatcgaggacgccagc
agcaagctgcactgtaactgcggtgccaagaagtgtcgccgattcctcaactga
DBGET
integrated database retrieval system
