Dendrobates tinctorius (dyeing poison frog): 141087752
Help
Entry
141087752 CDS
T11000
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
dtc Dendrobates tinctorius (dyeing poison frog)
Brite
KEGG Orthology (KO) [BR:
dtc00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dtc01001
]
141087752 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
dtc04131
]
141087752 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
dtc04147
]
141087752 (LRRK2)
Enzymes [BR:
dtc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
141087752 (LRRK2)
Protein kinases [BR:
dtc01001
]
Serine/threonine kinases: TKL group
LRRK family
141087752 (LRRK2)
Membrane trafficking [BR:
dtc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
141087752 (LRRK2)
Exosome [BR:
dtc04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
141087752 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_14
Ank_2
Arf
WD40_2
Beta-prop_RSE1_2nd
WD40_CDC20-Fz
Gtr1_RagA
ARM_LIN_2nd
nSTAND3
Beta-prop_EML_2
ABC_tran
AAA_16
Kdo
AAA_22
LRR_NXF1-5
NACHT
G-alpha
T2SSE
AAA_29
Motif
Other DBs
NCBI-GeneID:
141087752
NCBI-ProteinID:
XP_073429643
LinkDB
All DBs
Position
Unknown
AA seq
2520 aa
AA seq
DB search
MNSTVELVENVKKLVVRLRNVEEGKQIDNLVQILEDLHAHTFCDDATEIFSHVNVHLPLL
LVLESYIKVAVIQEAGWSLLCRLITVCPNILHSLHTPVDIGHEWEVLGVHQQILKILSAY
LTNLNVLTIALQALTSILESDVIHFMVLDHEADVFLLIFEAMKLFSDKEDIQIYGCQALY
LLLMKVPEEQLTEFVESKDHLIILKVLTQYKDTESVIYQALRVLIPLADPPCNVEVLMSG
NVRCYNIIMEAMKTFPNCENIQEVCCCLFQKLTFGSFFNILVLNEAHEVIIKALISYSAN
SRLQAAALTCLALLTETIFLNKDLDDGEDAGNIRGQLYWFEASFKALKLHKKNTEVQEAA
CWSLNNLLMYHPELHDRIGDEQNQYPLHREVMLSMLMHSSSKEVFQATTTALATLAGHNA
IIRKILLEKGVHINVLEIMKEHLDSPEAAESACRVLFQLFNGSSFNLDMLTVTMASLLNV
MKRHKKVPGVQLKALRVMVQILCDDTTYDVTNSPIKTEESSFLNLPRKVIRNQCLLEGTH
KFILQALNKFISNPGIQECGLKVVRCLSECSGSLELLSEQGAFDTILHSIQMYPGNEEIQ
YFGISLLSFLISRKNLCIETMHLLSSHLVCTLQRYKDAARIQEEGFRAALTLINLSYSFA
KLLELQDFDTVLFYQMSMCLANKRDQKFQILCYRCFAEMTLEDDLKNRLLVKACAEDHLV
IVEALLLLGADINKITKPTPLIFQVCEKGTNAKLVELLLNHGVHEQDSRKALEASIKNGN
NEVISLLLKKLGLDAANNSICLGGFHMGKIQPSWLNPLFSEKQNALKNPSADLEANQDSG
PILARMVFRYQSKHHGCRSSGDLSSVHDLLDKDDSFSHDGFDDVFANNDDIDSEGSEGTH
PVKKPHSFVSLDIHKENSKLNHVTSDQRQTNSLGGFGDEPNLRRRKDFPQIDYPLGKALF
SLHMKRTDSTSSLTEKEHIRSLDLSANDLESIDLINKKSQLTIHLERLEKLELQQNALTS
IPKSLFDVFKSLAYLDLRNNNFKTFPTAILEMSSISFLDISRNEIGPLLDLHANTICLTL
KHLNLSYNQLKEVPKCIGNIAQKLEELILEGNSISQIHVPLSLPELRTLNVNKNMISALG
PNILNNCVRLEVFCAAMNQLASLPNMPSKLTTLRLSHNKFTNFPKEILQLSYLRTVDLSN
NQINNLPSPLEWTSVNLREIMLNHNQISVLNLEDLRKDANRWSRLEKLHLSNNMIKEIPP
EIGFLVNVTCFDISHNPDLRSFPDEMGKLTKVWDLPLDGLHLDFDLKHIGCKARDLIRFL
QQRLKKAVPYNRMKLFIMGNTGSGKTTLVHQLMKERHPGHGAEKATIGIDVKDWPILIRG
KVKKEITLNVWDFAGQEEFYSTHPHFMTPRALYLVVYDLSKGASEVDAIKPWLFNIKARA
SSSPVILVGTHLDVSDEKQRKACINKIKMELFNQRELPCVQDYHFVNATEESDALAKLRK
SVIKECLNFKIRDQAVLGQLIPDSYLELEKRILIEKQNAPVAFPVINHKRLQDIVLENQL
DLDEHELQHAVHFLNESGVLLHFEDPALQLQDLYFVDPEWLCKIMAQILTVKVEGCHRYP
KGIIHCLDVEKFLFKKKNFPENYILQYFKLLEKFQIALPLSEKQLLIPSSLSDHRPVIEL
PHCENSEVIVRVYEMSYFPMGFWSRLINRLLEVSSYMLSGRERVQRPNRMYWRQGIYLNW
SPEAYCLVESTSLYDSPNSFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLETDISG
EGETLLKKWVLYSFDDGQEHKKILLSDLLVKAEEGDLLVNPEDPRFTIPISQIAPDIVLA
DLPRNIMLNNEELEFDQSPEYLLGDGGFGSVYRAVYRGKDVAVKIFNKYTSPRLLRQELA
VLSHLHHPSLVCLLAAGVRPRMLVMELAPKGSLDHLLQQDNSSLTRTLQHRIALHVADGL
RYLHSSMIIYRDLKPHNVLLFTLHPSCEVIAKIADYGIAQYCCRMGIKTSEGTPGFRAPE
VARGNVIYNQQADVYSFGLLLYDILTAGARMVEGLKFPNEFDELAVNGKLPDPVKEYNCA
AWPEVEVLIKKCLKENPQERPTSAKVYEILNSAELLCLRRNLVIPSPLTAECMVSANPRL
KVPTVLVGSGSTDKGQLSCLNLVKGGHTCEDFCDSAILCLAFVTVPDEREHWILVGTQSG
DILAAHAEDVKRKHHLQKLPDSITCFLFSCQIRQSQKKYFLLVGTANGHIAVFEAAAIKS
SNVTPMKMLNVGDICTPVMSLCESTYSSEKTAVWGICGTKILFLSNDFSVQKAIETKNAM
PFSHGSVSDSNITSIAVDKYIYVAKKYSPYVEIWDKKTEKLCEVLDCAQLLKEEIAKQRK
LNKEDSYTARVKAMFLQKNTALWVGTGGGHILLIDISTRRPIRIISSFCDSIRCMVPSQL
DKGNVKNVVLVLGCRGSPHKEIQSFLSVWDMNLPHEVQNLKKHNEIRQELAEKSRGLSLD
NT seq
7563 nt
NT seq
+upstream
nt +downstream
nt
atgaacagcacggtagaactagtagagaatgtcaagaagctggttgtccgccttagaaat
gtggaggaagggaaacagatagacaatctggttcagatattggaagatttgcacgctcac
accttttgtgatgatgctacagaaatattcagtcatgtgaacgtccatttgcccctgtta
ctggtgctggagtcgtacataaaagttgctgtcatacaggaggcaggctggtctctgcta
tgcagattgataacggtgtgcccaaatatactacatagtttacatactccagttgatatt
gggcatgagtgggaagtccttggcgtccatcaacagattctgaagatcctgtctgcttat
ctcactaatctcaatgtcttgacgattgcattgcaagctttgaccagcatccttgaatcg
gatgtaatacattttatggttttggatcatgaagccgatgtttttctgttaatttttgaa
gccatgaagctgttctcagacaaagaagatattcagatatatggctgccaagctttatat
ttgcttctaatgaaagttccagaagagcaattaaccgagtttgtagagagcaaagatcat
ctgatcatcctgaaggttcttacacagtataaagatacagagtctgtcatttaccaagct
ttacgtgttttgatcccattggcagacccaccttgcaatgtggaagtgcttatgtctggc
aatgtcagatgttacaacataataatggaagcaatgaaaacatttccaaactgtgaaaac
atacaagaagtttgttgctgcttgttccagaaacttacatttggaagcttttttaatatc
ctggtgttaaatgaagcccatgaagtcattataaaagctctgataagctattctgcaaat
tcaagactgcaagcagctgcgctaacatgcctggctcttctaacggaaactatatttttg
aacaaggacttggatgatggagaagacgccggcaatattagagggcaactgtattggttt
gaagcttcatttaaagctttaaaacttcataagaagaacacagaagtccaggaagctgct
tgctggtccttgaataatcttcttatgtaccatcctgagcttcatgatagaatcggagat
gaacaaaatcagtaccctttacacagagaagtcatgctgtccatgctgatgcactcttcc
tccaaggaggttttccaagcaaccacaactgctttggccactctcgctggacacaatgca
atcattagaaagattttattggagaaaggcgttcatatcaatgtgcttgaaatcatgaag
gaacatctagattctccggaagcagcagaaagtgcctgtcgagtcctttttcagcttttt
aatggaagctcctttaatttggatatgttgactgtgacaatggcaagtctgttgaatgtc
atgaaaaggcacaaaaaggtacctggggtccagctgaaggctttgcgggtaatggtgcag
attttatgtgatgacactacgtatgatgtgacaaatagtcctataaaaacagaagagagt
tcattcctaaatctgccacgtaaagtgattaggaaccaatgcttgcttgaaggcacgcac
aagttcattttgcaagccctcaacaagtttatttctaatccgggaatacaagaatgtggg
ctgaaagtagtgcgttgtctgtccgaatgttcggggtctttggagttgctgtcagagcag
ggagctttcgatacaattttacacagtatccagatgtatcctggaaatgaagaaattcaa
tactttggtatctctctcttgtcttttctaatatcaagaaaaaacttatgcattgaaaca
atgcacttattatcaagtcatttggtttgtacattacagaggtataaggatgctgccagg
atacaagaagagggatttcgggctgccctaacacttataaatctttcatacagttttgca
aagcttttagagctacaggattttgacactgtacttttttatcaaatgtctatgtgcttg
gcaaacaaacgggatcagaagtttcagattttatgttatcgctgttttgctgaaatgacc
ttggaagacgatttaaagaacagattgcttgtgaaagcctgtgcagaagatcatttggtc
attgtggaagctttactattgcttggagcagatatcaataagataaccaagcccacacct
ttaatttttcaggtttgtgagaagggaacaaatgctaagttggtggagcttttgttaaat
catggagttcatgaacaagattcacggaaggctcttgaagcgagcattaaaaatggcaat
aatgaggttatcagcttgctgctgaaaaaacttggcttagatgctgctaataacagtatt
tgcctgggaggttttcatatgggaaagatccaaccttcatggcttaatcctctgttctca
gaaaaacaaaatgcacttaaaaatccttcagcagatctcgaagctaaccaagactctggg
cccattttggcaagaatggtgtttcgttaccaaagcaaacaccatggctgcagatcttca
ggagatttaagttctgtgcatgacttgcttgataaagatgattccttctcacatgatggt
tttgatgatgtatttgctaacaatgatgacatagatagtgaaggcagtgaaggaacacat
cctgtgaaaaaaccgcactcatttgtcagccttgatattcataaggaaaactcaaagctg
aatcatgtgacatcagatcagaggcagactaactccttgggcggatttggggatgaacct
aatttacgtagaagaaaagattttcctcaaattgattatcctttgggtaaagcacttttt
tcactgcacatgaagcgaaccgatagcacctcttcattgactgaaaaagaacatattcga
tccttagacctgtcagcaaatgatctggaaagcatagatttaataaataaaaaatcccaa
ttgaccattcatttggaacgtcttgagaaattagagctccaacagaatgctttaacatct
attcctaaatcgctctttgacgttttcaaatctttggcttatcttgatttgcgcaataac
aacttcaaaaccttccctactgctattttggaaatgagtagtatctccttccttgatata
tcgagaaatgaaattggacccttgttagatttgcatgcaaacacaatatgcctaacattg
aagcatcttaacctgtcatacaatcagctgaaagaagttcccaaatgtattggaaatatt
gcacaaaaactagaagaattaatccttgaaggtaacagtatttcacagattcacgtacca
ctatccctgcctgagctccggacactgaatgtgaacaagaacatgatttctgcacttggg
cccaatatcctgaataactgtgttaggctagaggtgttttgtgccgcaatgaaccaatta
gcatcgttgcctaatatgccttcaaaattaacaaccttaaggctgtcccataataaattt
acaaatttcccaaaagaaattcttcagctctcatatttacggacagtggatttgagcaac
aatcagatcaataatctgccctctccactggaatggacttcagtaaatctgagagaaata
atgttgaaccacaatcagattagcgtgttgaatctggaggacctccgtaaagatgcaaac
agatggtcacgtcttgagaaactacatctttccaataatatgatcaaggagataccacct
gaaattggctttcttgtgaatgtcacttgttttgatataagccacaatccagatttaagg
tcatttcccgatgaaatgggaaagcttactaaagtgtgggaccttcctctggacggacta
catctggattttgatctgaagcatataggatgcaaagccagagaccttatccgatttctt
cagcagcgattaaaaaaggctgttccttataatcgtatgaagctgtttatcatgggaaac
accggaagtggcaagacaacgcttgtacatcagctaatgaaagaaaggcacccagggcac
ggtgcagagaaggccaccatcggcattgatgtgaaggactggcccattctaataaggggg
aaagttaagaaggaaatcacgctgaatgtctgggactttgcaggccaagaagagttttat
agcactcatccacattttatgactccacgtgctttgtatctcgtcgtttatgatcttagc
aaaggggcctcagaagttgatgcaataaaaccttggctctttaacataaaggcccgtgcc
tcttcctcacctgttattcttgttggaacacacctagatgtgtctgatgaaaaacagcga
aaagcctgcataaacaaaataaaaatggagctgtttaatcaacgtgagcttccatgtgtc
caggattatcattttgtgaacgctacagaggagtcagatgctttagcaaaacttaggaag
tcagtcataaaagagtgcttgaatttcaagatccgggaccaagcagttcttgggcagctg
attcctgatagttatctggaacttgagaagagaattcttattgaaaagcaaaatgctcct
gttgcatttcctgtaattaaccacaagaggctgcaagatattgtactagaaaaccagctg
gatttggatgagcacgaacttcagcatgccgttcattttctaaatgaatctggagtatta
ctgcactttgaggaccctgctctacagctgcaagatctttattttgtggaccctgaatgg
ctctgtaaaataatggcccagattttgacagtaaaagttgaaggatgccatagatatcca
aaagggattatccactgtctagatgtggaaaaatttctttttaaaaagaaaaattttcct
gaaaattatattttacaatattttaagcttctggaaaagtttcagattgctttacccttg
agtgaaaagcaacttctcattccaagcagtttatctgaccaccgaccagtgatagaacta
ccccactgtgaaaattcagaggttatcgtaagagtgtatgaaatgtcatattttcccatg
ggattttggtccaggctcatcaacaggcttttggaagtgtcatcatacatgctttctggc
cgagaaagagtccagcgccctaacaggatgtactggagacaaggtatctacctaaattgg
tctcctgaagcatactgtttggtggaatctacaagcctatacgatagcccaaatagtttt
ttgaaaattactgttccatcttgtagaaaaggttgcattctgctgggacaggttgtggat
catattgattcactaatggaggaatggtttcccggtttgttggaaactgatatttctggt
gaaggagaaacattgttaaaaaagtgggtgctgtacagttttgatgacggtcaagagcac
aaaaaaattctattatctgatttgctggtaaaagctgaagaaggtgacttgttagtcaat
ccagaagatccaagatttacaattccaatctcacaaattgctcctgatattgttctagct
gatttgccaagaaatatcatgctaaataacgaggagctagaatttgatcagtctcctgag
tacttactgggtgacggtggctttggatcagtctatagggctgtgtatagaggtaaagat
gtagcagtgaaaattttcaacaaatatacttccccaaggcttttaaggcaggaactggca
gtacttagtcatctccatcacccaagcctagtgtgtttacttgcagctggggttcgacct
agaatgctagtaatggaacttgctccgaaaggttcacttgatcatttgcttcagcaggac
aacagtagcctgactcgaactcttcagcacagaatagctcttcatgttgctgacgggctc
aggtaccttcattcatctatgatcatttaccgagatttaaaacctcacaatgttctgctg
tttacattacatccaagttgtgaagttattgccaaaattgcagactatggcattgctcaa
tattgttgcagaatggggataaaaacttcagaaggcaccccaggatttagagcacctgaa
gttgcaagaggaaatgtaatttacaaccaacaggctgatgtctattcatttggattgttg
ctctatgatattctgacagctggagctaggatggttgaagggttgaagtttccaaatgaa
tttgatgaattggctgtcaatggaaaattgcctgatccagtgaaagaatataattgtgct
gcatggccagaagttgaagttttgattaaaaaatgcttaaaagaaaatcctcaagaacgt
cctacatctgccaaggtatatgagatcctaaactctgcggagctcctgtgtctgaggagg
aatcttgtaattccaagccctttaacagctgagtgcatggtgtctgctaatccacgactt
aaggtgcccactgttttggttggaagcggcagtactgacaaggggcagctatcctgtttg
aacttagttaaaggtggacatacttgtgaggatttttgtgatagtgcaatcctttgtctt
gcatttgtgactgtccctgatgaaagagaacattggatcttggtggggacacagtctggt
gacattctggctgcacatgcagaagatgtaaagagaaaacatcaccttcagaaactgcct
gactccattacatgtttcttgttttcttgtcaaatacgtcaaagtcagaagaaatatttt
ctcctggttggaacagctaatggccacattgcagtttttgaagctgctgcaataaagagc
agtaatgttactcctatgaagatgcttaatgtgggagatatctgcacaccagtcatgtcc
ttgtgcgaatcaacatattcctctgagaagactgctgtatggggaatttgtggaacaaaa
atcttattcctttctaatgatttctccgttcaaaaggctattgaaacaaaaaacgccatg
ccgttttcacatgggtcagtgagtgattcaaatatcacttctattgcggttgacaagtac
atctatgtggcaaaaaaatacagtccgtatgtggagatttgggataaaaagacagaaaaa
ctatgtgaagtgcttgactgtgcccagctactaaaagaagaaattgcaaagcagagaaaa
ttaaataaagaagactcttataccgctcgagtcaaagcgatgtttttacagaaaaatacg
gctctttgggttggaacaggcggaggacatatcctgcttattgacatatcgactcgacga
ccgataagaatcatctctagtttctgcgactccattcgctgcatggttccttctcagcta
gacaagggaaatgtaaagaatgttgtgcttgtattaggatgccgtggctcaccacataaa
gaaatacagtcatttctttctgtgtgggatatgaaccttccgcatgaggtccaaaacctt
aagaagcataatgaaataagacaggagctggcagagaaatcaagaggcttatcactagac
tga
DBGET
integrated database retrieval system
