Dendrobates tinctorius (dyeing poison frog): 141101487
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Entry
141101487 CDS
T11000
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
dtc Dendrobates tinctorius (dyeing poison frog)
Pathway
dtc04217
Necroptosis
dtc04620
Toll-like receptor signaling pathway
dtc04621
NOD-like receptor signaling pathway
dtc05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
dtc00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
141101487 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
141101487 (TYK2)
04621 NOD-like receptor signaling pathway
141101487 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
141101487 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
dtc01001
]
141101487 (TYK2)
Enzymes [BR:
dtc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
141101487 (TYK2)
Protein kinases [BR:
dtc01001
]
Non-receptor tyrosine kinases
JAK family [OT]
141101487 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kdo
Kinase-like
RIO1
ABC1
FERM_C_FAK1
RA
RNF34L-like_3rd
Motif
Other DBs
NCBI-GeneID:
141101487
NCBI-ProteinID:
XP_073446712
LinkDB
All DBs
Position
Unknown
AA seq
1179 aa
AA seq
DB search
MALCQCTVRNSDSDMEGCTFTGVGLRVFLYWSNGKEHYVSFTQNVTTAEEICIHVAQRLG
ITPLCYTLFSLYDVQAKHWYPPNHEFRITKDMKLLLHFRMRYYFRNWHGMNEKEAVVCRN
IPKVGDGEDKSRAEQSGAILDLASFEYLFEQGKFDFVNDVVSLKDFHSEQDVQKFKNESL
GMAVLHLSHIAIKKKVSLEEVAKQISFKECIPKSFCRQIQQNNYLTKLRMRSVFKKFIRH
FHLHTVSAGKLSEEDVMYKYLSTLENLAPRFGCEVFGTLSLELPTEGEKLPLYINGGGYM
DQSKSVSSEATATHQVLVSGMEGIQWRQKKEEEAAESGHHRNYFSKRSRNKGQKAAKPAT
EASEPKWEPFCDFQDITHIVISKSRVSINCQDNRCLEIVLSSYEEALSFVSLVDGFFRLT
TDSNHYLCHEVAPPRLVMSAVNGIHGPLQEQYVIQKLKREEQADGPYIIRWSAFTFNRLI
MTVKGISQNKGISYKQFRIDKEDDMYTLEQWERGFTSVKELTDNLRGCTLKSGQEVFHVK
QCVLPKSGEVSNLTICRKGKSSKENALSRNLNLSQLSFHQIRKNEITQKSHLGQGTRTNI
YEGVLIVSGGGEHDLDYDYREQNNNSRDLRVVLKVLDPSHQDISLAFFETASLMSQVSHI
HLVFVHGVCVRESENIMVEEFVEHGPLDVCLRKDKSLISAGWKVTVARQLASALSYLEDK
RLVHGNVCAKNILLARKGLEDGSSPFIKLSDPGVTFTVLSREERVDRIPWIAPECVRNAS
HLSTAADKWSFGTTLLEICFNGEVPLKERTASEKERFYEKELGLPEPSCKELADLIGVCH
NYNPSGRPSFRTILRDLTQLQPLDLSDIGSISPDFSITDPTVFQKRYLKKIRELGEGHFG
KVSLYCYDPNNDGTGEMVAVKSLKSGCSQQLETSWKGEIRILKTLYHENIVKYKGCCSEQ
GDKIVQLIMEYVPLGSLRDYLPKHNVQLPRMLRFAQQICEGMAYLHSQHYIHRDLAARNV
LVENENVVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYATECLKECKFFYSSDVWSFGV
TLYELLTQCDTNLSPPTKFIEMIGVTQGQMTVVRLIDLLDRGQRLSCPDDCPPEIYKLMK
NCWETEASLRPSFPTLIPILKTFHNTYSSRQAPSVQELL
NT seq
3540 nt
NT seq
+upstream
nt +downstream
nt
atggccttatgtcagtgcaccgtcaggaacagcgactccgacatggaaggctgcaccttc
accggggtcggccttcgggtgtttctgtattggagcaacggaaaagagcattatgtcagc
ttcacgcagaacgtcaccacggccgaggagatctgcatccacgtggcacagaggctgggt
atcacacctctgtgctacacattgttctccctgtacgatgtgcaagctaaacactggtat
cccccaaaccatgaattcaggatcacaaaggacatgaaactgctcctacacttcaggatg
aggtattatttcaggaactggcatgggatgaatgagaaggaagcggtggtttgccgcaac
atccctaaggtcggtgacggtgaggacaagagtcgggcagagcagtccggtgccatcctg
gacttggcatcattcgagtacctatttgagcagggcaagtttgactttgtgaatgatgtg
gtgtcactgaaggatttccattccgagcaggatgtgcagaagtttaagaacgagagcctg
ggcatggccgtccttcacctgtcacacatcgccatcaagaagaaagtgtcactggaagag
gtggccaagcaaataagttttaaggaatgtatccccaaatccttctgccggcagatccag
cagaacaactaccttacaaagctccgcatgaggagcgtttttaagaaattcatccgccac
ttccacctgcacacggtgagcgccgggaagctgagcgaggaggacgtcatgtacaagtac
ctgtccaccttggagaacctggcccccagatttggctgcgaggtgttcgggaccctgagc
ctggagcttcctacagagggagagaaacttccgttgtacattaatggcggcggctacatg
gaccagagcaagtccgtgagcagcgaggcgacggcgacgcaccaggtccttgtcagcgga
atggaggggatccagtggcggcagaagaaagaggaggaggcagcagagagcggccatcat
agaaattacttcagcaagagaagccgcaacaaaggacagaaggcggcgaaaccggcgact
gaagccagcgagcccaagtgggagccgttctgtgacttccaggatatcacccacatcgtc
atcagcaaaagccgcgtcagcatcaactgccaggataaccgctgcctggagatcgtcctg
tcttcatatgaagaggcgctgtcctttgtttcgctggtagatggcttcttcaggctcacc
acagactccaaccattacctgtgccacgaagtggcccctccacgcttggtgatgagcgct
gtcaatgggattcacgggcccctacaggagcagtacgtcatccagaagctgaagcgcgag
gagcaggcagacggcccgtacatcatccgctggagcgccttcaccttcaaccggctcatc
atgactgtaaaaggcatcagccagaataaagggataagttataagcagttccggatagat
aaagaggacgacatgtacacgctggaacagtgggagcgcggcttcaccagcgtcaaggag
ttaacggacaacctgcggggctgcacgctgaaatctggccaggaggtcttccatgtgaag
cagtgtgtcctgccaaaatctggagaagtttccaacttaaccatctgtcggaaagggaag
agcagcaaggaaaacgcattgtccaggaatctaaatttgagtcagctcagcttccaccag
atccgaaaaaacgagatcacacaaaaatcccacctgggtcaggggacccgtacgaatatc
tacgagggggttctcatagtgagcggtggtggtgagcacgacttggactatgattaccgg
gagcagaacaataactcccgtgatctacgagtggtcctgaaagtgctggatcccagtcac
caagacatatcgctggctttcttcgagactgcaagtctgatgagtcaggtctcccacatc
cacctggtttttgtccatggggtttgtgtccgggaatcggagaacatcatggtggaggag
ttcgttgaacacggcccgttggatgtttgcctgcgaaaggataaatctcttatctctgct
gggtggaaagtcacagtggccagacagctggcaagtgccctgagttatctggaagataag
cgtttggttcatggaaatgtctgtgcgaagaacattcttctggccaggaaaggtctggag
gacgggtcctctccattcatcaagctgagtgaccccggagtgacgttcacggtgctgtcc
cgagaagagcgggtggacaggatcccctggatcgccccagagtgtgtccgcaacgcctcc
cacctgagcacagccgcagataaatggagcttcgggaccaccctgctggaaatatgtttt
aatggggaagtgcccttaaaggaaaggaccgcttcagagaaggaaagattttacgaaaag
gagttgggcctccccgagccttcctgcaaagagcttgctgacctcataggtgtatgtcat
aattacaacccctcggggagaccgtccttccggaccatcctcagagaccttacccagctc
cagcccctcgatctttctgacattggctccatcagtcctgacttctccatcacggaccca
accgtgttccagaagcgatacttaaagaagatccgggagctgggagagggacactttggg
aaagtgagcctgtactgctacgatccaaataacgatgggacaggggagatggtggctgtg
aagtctctgaagtctgggtgcagtcagcagctggagaccagctggaaaggagaaatccgg
atactgaagaccctctaccatgagaacattgtgaaatataaaggctgctgcagcgagcaa
ggagataagatcgtgcagctcattatggagtacgtccctctgggcagtctgcgggactat
ctacctaaacacaacgtgcaactgcctcggatgttacggtttgcacagcagatctgtgag
ggcatggcatacctgcactctcagcattacatccatagggacctcgctgcccggaacgtc
ctggtggagaatgagaatgtggtgaagattggagattttggcctcgctaaagccgtgccg
gaaggacacgagtattaccgcgtaagagaggatggcgatagccctgtgttttggtacgcc
acggagtgtttaaaggaatgcaagttcttctattcctctgatgtctggtcgtttggggtg
acgctctatgaacttttgactcaatgtgacaccaatctcagtcccccgactaaattcata
gagatgattggcgtcacccaaggacagatgacggtggtgcggctgatcgatttgttggac
cggggccagagactttcttgtccggatgattgtccaccagagatctataaactgatgaag
aactgctgggagacggaggcgagtttacggccatcgtttccaaccctcatcccgatcctg
aagaccttccataacacgtatagcagcagacaggcgccatctgtccaggagctgctatag
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