Desulfurobacterium thermolithotrophum: Dester_0966
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Entry
Dester_0966 CDS
T01427
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dte
Desulfurobacterium thermolithotrophum
Pathway
dte00300
Lysine biosynthesis
dte00550
Peptidoglycan biosynthesis
dte01100
Metabolic pathways
dte01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dte00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Dester_0966
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Dester_0966
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Dester_0966
Enzymes [BR:
dte01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Dester_0966
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADY73605
UniProt:
F0S433
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Position
complement(969364..970671)
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AA seq
435 aa
AA seq
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MRAEEVAKIVKGKLIGNGKVNSIEFDSRNVKKGSLFVPLRGNRDGHQFIKDAFQNGASGT
LSERTLPIPEGKFLIEVKNTFEAFKLLGKWKRGNFNGTTIAITGSVGKTTTKELLTHVFS
KFFKTYRNVKSFNNILGLTYTLSNLPLDTELYIQELGTNRQGEIPELVEIVKPEISVVTA
VEKAHTAGFKDISDIVKEKLSITEGAILSIVPIQFKEFSKSKETITFGREGDIKLLDVQL
FPNKTEFLIESFGRRLQFFSPIPGLGVVNSTLIAVGLAEVFKVNIEKVSELIRTFTPPEM
RLTVEQLNKVILIDDSYNANPKSMENAIKVLSLQELPKVAIIGEMLELGEESKKEHEKIG
ELLNHAKVETLIAYGKETESTFKVFKGKKSYFTSQEELIKFIKTFHFQGKAVLVKGSRGN
RLEKIARIIRERYKS
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgagagcagaagaagttgcaaagatagttaagggaaaacttataggaaacggaaaagtt
aattcgattgaatttgattcaagaaatgtcaaaaaaggaagtctttttgttccactaaga
ggaaatcgagatggacatcagtttataaaagacgctttccaaaacggcgctagtggtacc
ttatctgagagaactcttcctattcccgagggaaaatttttaatagaagtaaaaaataca
tttgaagcttttaaacttttaggaaaatggaagagaggaaattttaatggaaccactatt
gcaatcactggaagtgtagggaaaacgacaacaaaagagctcttaactcacgttttttct
aaattctttaaaacttatagaaatgtaaagagtttcaacaatattttgggattgacttat
acattgtcaaaccttcctttagatactgagctttacattcaagaacttggaacaaatagg
caaggagaaatccctgaattagtagaaatcgttaagcctgaaatttccgtggtaacagca
gttgaaaaagcccacacagcaggttttaaagacatttcagatatagttaaggaaaaactt
tctataacagaaggtgctatactgtcaatagttcctattcagtttaaagagttttcaaaa
agtaaagaaacaataacttttggtagggaaggagatataaaacttttagatgtacagctt
tttcctaataaaaccgaatttctaatagaaagttttggaagaagacttcaatttttttct
cctattccaggtttaggagtagtaaattccacccttatagcagttggactagcggaagtt
tttaaagttaacattgaaaaagtttcagagctgataagaacatttactccaccagaaatg
agacttactgtagagcaacttaacaaagtaattctcatagatgactcctacaatgcaaat
ccgaaatctatggaaaatgcaataaaggtcctgtctcttcaggaattaccaaaggttgca
ataattggagagatgcttgaattaggagaagaatctaaaaaagaacacgaaaagatagga
gagctccttaaccatgccaaagtagaaacgcttatagcgtatggaaaagaaacagaaagt
acttttaaagtatttaaaggtaaaaaatcttactttacaagtcaggaagaacttattaag
tttattaaaactttccatttccaaggtaaagctgttttagtaaaaggttctcgaggaaac
cgattagagaagattgcaagaataataagagagaggtataaaagttga
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