Dictyoglomus thermophilum: DICTH_1068
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Entry
DICTH_1068 CDS
T00774
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
dth
Dictyoglomus thermophilum
Pathway
dth00290
Valine, leucine and isoleucine biosynthesis
dth00620
Pyruvate metabolism
dth01100
Metabolic pathways
dth01110
Biosynthesis of secondary metabolites
dth01210
2-Oxocarboxylic acid metabolism
dth01230
Biosynthesis of amino acids
Module
dth_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
dth00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
DICTH_1068
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
DICTH_1068
Enzymes [BR:
dth01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
DICTH_1068
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
ACI18951
UniProt:
B5YEF8
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All DBs
Position
1045941..1047515
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AA seq
524 aa
AA seq
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MKKVFLYDTTLRDGAQSERISFSLEDKIRIAQKLDEFGIDYIEGGWPGSNPKDLNFFKRI
KEIPLKHAKIAAFGSTRRAQVAPEDDSNLKALLESETPVVTIFGKSWNLHVTEVLRTTLE
NNLKMIYDSIKYLKSFGKEVIYDAEHFFDGFKSDPEYALSTLEAASEGGADWIVLADTNG
GTLPWEVEEIMEKVMERIKKPIGIHAHNDSGLAVANSIVSVRKGATQVQGTINGYGERCG
NANLCTIIPILQLKMNIEVISEEKLSQLTDLANWVSEIANLPPDPSSPFVGRSAFAHKGG
VHVNAVLKNPRSYEHIDPTKVGNKRRILVSELSGTSTIVSKVKEFNIDLDRDSPLAKLIL
DKIAHLENEGYYFEGAEASFELLVRHLLGQETKLFDLISLRVLIEKIGDSGETITEATLK
LKVKDQIVHVAAEGDGPVHALDQALRKALVEFYPELKNIHLSDFKVRVINGNAGTAAKVR
VLIDSTNDKGDTWSTVGVSTNIIEASWQSLVQSIEYGIMKMREN
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaaagtttttttgtatgataccaccttaagagatggtgcccagagtgaaagaatc
tcattctctcttgaagataaaataagaatagcacaaaaactggatgagtttggaatagac
tacattgagggaggatggccagggtctaatcctaaggatttaaacttcttcaaaagaatc
aaagaaattcccttaaaacacgcaaaaatagcagcctttggaagtacaagaagagcacaa
gtagcacctgaagatgactctaacttgaaagctttacttgaaagtgaaaccccagtagtt
actattttcggtaaaagttggaatttacatgttacagaggtattaagaaccacattggaa
aacaacctaaagatgatctatgattctataaaatatctaaaaagtttcggtaaagaagta
atatacgatgcagaacacttcttcgatggtttcaaatcagatccagaatatgctctttca
accttagaagctgcatcagaaggtggtgctgattggatcgtactcgcagatacaaatggg
ggtactcttccttgggaagtagaagagattatggaaaaagtaatggaaaggattaaaaaa
ccaataggaatacatgctcataatgattcaggtcttgctgtagcaaattccatagtatca
gtaagaaaaggagcaacacaagttcaaggcaccataaatggatatggggaaagatgtgga
aatgcaaatttatgtaccataatccctattcttcagttaaaaatgaatatcgaggtcata
tctgaagaaaaactatctcaacttacagatcttgcaaattgggtttctgagattgctaac
ttacctcctgatccatcttctccatttgtaggaagaagtgcctttgctcataaaggtggt
gttcatgttaatgctgttctcaaaaatccaagatcttatgaacatatagatcctactaaa
gtgggtaacaaaagaagaatacttgtctcagaactttctggtaccagtactatagtctca
aaggtgaaagaattcaatatagatcttgatagggattcacctttagctaaactaatattg
gataagattgcccatttagaaaacgagggttattactttgagggtgctgaggcttctttt
gaactcctagtaaggcatcttttgggccaagagacaaagctatttgatttaataagttta
agagtacttattgagaaaataggagactctggcgaaacaattacagaagcaacattaaag
ctcaaagtaaaggatcaaattgtccatgtagctgcagaaggtgatgggcctgtgcatgct
ttagaccaagctttaagaaaagctcttgtcgaattctaccccgaactaaagaatattcat
ctttccgactttaaagtaagggttataaatggaaatgcgggtacagctgcaaaagtcaga
gtattaattgattcaaccaatgataaaggtgatacttggagtactgtaggagtctctaca
aatattatagaggcaagctggcagtctttagtgcagagtatcgaatatggaataatgaaa
atgcgggagaattaa
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