Desulfosarcina widdelii: DSCW_25520
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Entry
DSCW_25520 CDS
T06303
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
dwd
Desulfosarcina widdelii
Pathway
dwd00300
Lysine biosynthesis
dwd00550
Peptidoglycan biosynthesis
dwd01100
Metabolic pathways
dwd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
dwd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DSCW_25520 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DSCW_25520 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DSCW_25520 (murF)
Enzymes [BR:
dwd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DSCW_25520 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Prot_ATP_ID_OB_C
Motif
Other DBs
NCBI-ProteinID:
BBO75135
UniProt:
A0A5K7Z351
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All DBs
Position
complement(2675949..2677370)
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AA seq
473 aa
AA seq
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MTSYRWTIRDVLTATGGSLVSGTDGREFAGIGIDSRTIESDRIFLAIVGESHDGHRFVAD
VLSKGGQGFVVAEDQAVDLPLDRMRASGAACVTVADTTVALGDLARFNRNRKPLKVLAIT
GSNGKTSTRMLTEQVLSGKYATLSTQGNLNNHIGLPLTLLRRAPQHEAAVVELGMNHPGE
ITRLGGICQPDVGIITNVAPAHLEGLGTMDNVAAAKGELLTTIRSGGTAILNADDVRVAA
LADGCPCRVLFFGISERSGIRAENVRPDGKGLVFTLITPSGEVDIRMATPMQAMVANALA
AAAAGEVLGISLDRIKDGLEAFSPGAGRMAIRELEGGIRLLDDTYNANPGSMAAAIETLA
AMRADGRTHAVLGDMLELGDLSHLLHRKIGRAVGEAGIDRLYAAGRFAFEVAEGAREGRM
TDDRIFVGTKAEIIELLREELRAGDQILVKGSRGMAMEEVAEEIVRWTTEGTR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgacatcctacaggtggacaatccgcgatgtgctgaccgccaccggcgggtcactggtt
tccggaaccgatggccgggaatttgccggcataggaatcgattcgcgcaccatcgaatcg
gaccgtatttttttggccattgtcggcgagtctcacgatggacaccggttcgtggccgac
gtgctgtcaaaagggggccaggggttcgtggtggctgaggaccaggcggtcgatttgccc
ctggaccggatgcgggcatcgggggcagcatgcgtgaccgtggcggacaccaccgtggcc
ctgggcgatctggcccggttcaatcgcaaccggaaaccgctcaaggtcctggcgataacc
ggctccaacggcaaaacctcgacccgcatgctcaccgagcaggtgttgtccggaaaatat
gcaaccctgagtacccaaggcaacctgaacaaccatatcggtctgccactgacgcttttg
cggcgggcgccgcagcacgaagccgccgttgtcgaactggggatgaatcatcccggcgag
atcacccgtctgggagggatctgccagccggatgtgggaattattaccaatgtcgccccg
gcccatctggagggcctgggaacaatggacaacgtggctgcggccaaaggcgaactgctg
accaccattcgatccggcggaacggccatcctcaacgcggacgatgtccgggtggcggcc
ctggccgatggttgtccctgccgggtcctttttttcggaatttctgaacggtccggaatc
cgggctgagaacgtccgtccggatggaaaggggctggtcttcacactgatcacgccgtcg
ggcgaggtcgacatccgtatggccacgccgatgcaggccatggtggccaacgccctggcc
gcggcggcggcaggcgaggttctgggcatatccctggaccgcatcaaggacgggctggaa
gcattctcgcccggtgccgggcgaatggccatccgcgaactggaaggcggcatccggctg
ctggacgatacatacaacgccaatccgggatccatggccgcggccatcgagaccctggcg
gccatgcgggccgacggtcgcacccatgccgtgctgggggacatgctggaactgggcgac
ctgtcccacctcctgcaccgaaagataggccgggcggttggcgaagccggcatcgaccgg
ttgtatgcggccgggcgtttcgctttcgaggtggccgaaggggccagagaagggcggatg
accgatgatcgtatctttgtcggcaccaaagccgaaattatcgagctgttaagggaagag
ctgcgagcgggcgaccagatcctggtgaaaggatcccgcggtatggccatggaagaagtg
gcggaagaaatcgtccgttggacaacagaaggaacccgatga
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