Drosophila willistoni: 6642061
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Entry
6642061 CDS
T01067
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
dwi
Drosophila willistoni
Pathway
dwi00230
Purine metabolism
dwi00670
One carbon pool by folate
dwi01100
Metabolic pathways
Module
dwi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
dwi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
6642061
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
6642061
Enzymes [BR:
dwi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
6642061
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
6642061
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
6642061
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
AIRS
GARS_C
ATP-grasp_3
ATP-grasp_2
ATP-grasp
ATP-grasp_4
CPSase_L_D2
RimK
ATPgrasp_ST
Motif
Other DBs
NCBI-GeneID:
6642061
NCBI-ProteinID:
XP_002065083
UniProt:
B4MUE3
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Position
2R
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AA seq
1358 aa
AA seq
DB search
MSQRVLVIGSGGREHAICWKLSQSKAVSRIYALPGSFGIGQVEKCENLIAKILDPKDFEG
IAKWSKLNDISLVIVGPEDPLALGLGDVLQKAGIPCFGPGKQGAQIEADKKWAKDFMLRH
GIPTARYESFTDTEKAKAFIRSAPYQALVVKAAGLAAGKGVVVAANIEEACQAVDEILGQ
LKYGQAGATLVVEELLEGEEISVLAFTDGKSVQAMLPAQDHKRLADGDNGPNTGGMGAYC
PCPLISQPALDLVQRAVLERAVQGLTKERISYQGVLYAGLMLTRDGPRVLEFNCRFGDPE
TQVILPLLDSDLFEVMQACCTGELDKLTLQWRNGVNAVGVILASAGYPETSTKGCQITGL
PTANTSTQLVFHSGLSVNAQNEPQTNGGRVLIAIALDSSLKVAASQATKLAASIKFSGAG
AQYRTDIAQKAFKMALASAPSLSYKDSGVDIDAGDALVQRIKPLSRGTQRPGVLGGLGGF
GGLFRLKELAYKEPVIAEVTQGVGAKIQLALQHELYENVGYDLFATCANDLLELGAEPVA
FLDYIACGKLQVPLAAQFIKGMADGCRDARCALVGGETAEMPSLYTQGQHDMAGYCVGVV
ESSKILPRFDLYQPGDLVVGLPASGLHCADFNDLLTQLKAAKIDLKQRSPVEGGADGLSL
AQVLATPTQVYVQQLLPHLQAGNEIKALVHITHGLLNDVRRLLPAGYELTLDFGAVPIPQ
IFAWLAGQLKWSAQALLENHNCGIGMVVVLPRSSQLWRTSLPGAKVLGVLHRSQTETSIL
QVRNFEDQLERLAKPFGGLGQGERKLTPELMEIPVKDLDIPVRSDCFTNLTGRRLTRIPA
QYKDPILILGTDGVGTKLKIAQQTGRNGSVGIDLVAMCVNDILCNGAEPFSFSSYYACGK
WDEKLAIEVTNGVLEGTRQANSSFIVSHNAALPLLYEPQVYDLAGFALGIAERSGILPRL
EDIQPRDILIGLPSSGVHSNGFSLVHAVLKRVGLTVDDPSPFSQKTLGEELLVPTKIYVK
ALSTLLARPNHGIKALAHITGGGLSENIPRVLRKELAVRLDANRYQLPPVFAWLAKAGNI
TPTELQRTYNCGLGLILVVNNTDTMNVLNELRYPQRAVVVGEVTLRKDPKKPQVYVENFE
AALARTQKLMAKPRRRVAVLISGTGSNLQALIDASRDSSQCVHADIVLVISNKAGVLGLE
RAARSGIPSLTISHKDFPTREDYDAELTRHLQAANVDIVCLAGFMRVLSVPFVRTWRGRL
INIHPSLLPKYPGLNVQARALEAGERESGCTVHFVDEGVDTGAILLQAPVPILPNDDVDA
LTQRIHQAEHWAFPRALALLASGSAQLGPDGKCLSKDQ
NT seq
4077 nt
NT seq
+upstream
nt +downstream
nt
atgtcacagcgcgtcttggttatcggtagtggaggacgggaacatgccatttgctggaaa
ttatcgcaatcgaaggcggtatctcgtatttatgctttacccggcagctttggcattggc
caagtggaaaaatgtgaaaatttaattgccaaaatattggatccaaaggattttgagggc
atagccaagtggagcaagctcaatgatatatctctggttattgttggacctgaagatcct
ttagctttgggccttggtgatgttttacaaaaggcgggcattccatgtttcggccccggc
aaacagggagctcaaattgaagccgataaaaaatgggccaaggactttatgttgcgtcat
ggtataccaacggcacgctacgaaagttttacggatacggaaaaagctaaagcatttata
agaagtgctccatatcaggcattggtggttaaagctgctggcttggcggctggtaaaggt
gttgtggttgctgccaatatagaggaagcatgccaggcagttgacgagatattgggacaa
ctaaagtatggtcaggccggggctactttggtggtggaagaactgctagagggtgaagaa
atatccgtattggccttcacagatggtaagagtgtgcaagccatgctaccagcacaggat
cataagcgtttggccgatggtgataatggacccaataccggaggaatgggtgcctattgt
ccatgtccgttgataagtcaaccagctttggatttggtccaaagagctgtactcgagcga
gctgtccagggcttgacaaaggaacgaatctcatatcaaggtgtactctatgcgggtctc
atgctgacacgcgatggaccgcgcgtattggaattcaattgccgctttggtgatccggaa
acgcaagtgatactccccttgttggactctgatctctttgaggtcatgcaggcatgttgt
acgggtgaattggataaattaactttacaatggcgaaacggtgtcaatgctgttggtgtc
attctcgccagtgccggctatccagagacatcgaccaagggttgtcagattactggtctc
ccaactgccaatacttcaactcaattggttttccatagcggtctctcggttaatgcccag
aatgaacctcagaccaatggtggtcgtgtcctgattgcaattgctttggactcaagtcta
aaggtggcagcaagtcaagccaccaaattggcggcgagcattaaattttctggagctggt
gcacaatatcgtacggatattgcccaaaaggctttcaaaatggccttggcttcggctccc
tcgctaagctataaggacagcggtgtcgatattgatgctggcgatgccttggttcaacgt
attaaacccttatcccgtggcactcaacgtcccggggtattgggcggcttgggtggcttt
ggtggtctgtttcgtctaaaggaacttgcctacaaggaaccagtgattgctgaagttacc
caaggagtgggcgcaaaaattcaattggccttacagcatgaactctatgagaatgttggc
tatgatctatttgccacatgtgccaatgatctgcttgagctcggagccgaaccggttgca
tttctggattatatagcttgcggcaagttgcaagtacccttggcagcgcaatttattaag
ggcatggctgatggttgtcgtgatgcacgttgcgccttagttggtggcgaaactgctgaa
atgccttcattgtatacacaaggacaacacgatatggccggctattgtgtgggtgttgtg
gaatcatctaaaattttgccacgctttgatctctatcaaccaggagatttggttgttgga
ctgccagcctcgggtctacattgtgctgactttaatgacctactcacccaattgaaggct
gctaaaattgatctaaagcaacgttcacccgtcgaaggtggggctgatggcttgagtttg
gctcaggttttggccacacctacacaagtttatgtgcaacaattgctgccacatttacag
gccggaaacgagataaaggctttggtgcatataacccatggcctacttaacgatgtgcgt
cgtctattgcccgctggttatgagctaacattagactttggagctgtacccataccacaa
atatttgcttggttggctggacaattgaaatggagtgctcaagcattgcttgagaatcat
aattgtggcattggaatggttgtggttctgccacggagtagtcaactgtggcgcacatca
ttgccaggggcaaaagtcctgggcgtactacatcgttctcagacagaaacttcaattctg
caagtgcgcaactttgaagatcaattggaacgtttggcaaaaccatttggaggtctgggt
cagggggaaagaaagcttacaccagaattgatggaaattcccgtaaaagatcttgatata
cccgtacgttcggattgtttcacaaatttgacgggacgtcgcttgacacggattcctgcg
caatacaaggatcccatacttatacttggcaccgatggtgttggtacgaaattgaaaatt
gcccaacaaactggacgaaatggtagtgttggcatcgatctggtggccatgtgtgtcaat
gatatactctgcaatggcgctgaaccctttagcttctccagctattatgcatgcggcaaa
tgggatgagaaactggccatagaagtgacaaatggtgttctagagggcacaaggcaagcg
aacagtagttttatagtttcccataatgccgctctaccattgctttatgagccacaagtc
tatgatttggctggttttgctctaggcatagcagaacgttctggtattctgccacgtctg
gaggatatccagccacgtgatatacttattggattgccgtcgtcgggagtgcatagcaac
ggcttcagtttggttcatgccgtcctaaagcgtgttggcctcaccgtcgacgatccatcg
cctttcagtcaaaagacattgggggaagagctcttggtgcctacaaaaatttatgtcaaa
gctttgtccacacttttggccagacctaatcatggtatcaaggcattggctcatataaca
ggcggtggccttagtgagaatataccaagagttttacgcaaggaattggctgtacgcttg
gatgcgaatcgttatcaattgcctccagtttttgcctggttggcgaaagctggaaatatc
acacccacagaattgcaaaggacctataattgtggattgggcttaattttggtggtcaat
aacacggacacgatgaatgtgctaaacgaattgcgttatcctcaacgtgcagtggttgtg
ggagaggtaactctgcgcaaagatccaaagaaaccacaggtttatgttgagaatttcgaa
gccgctttggccagaactcaaaagcttatggccaaaccccgacgacgtgtggccgtccta
atctctggcactggcagtaatcttcaggccctcattgatgcctcacgtgactcgtctcaa
tgcgttcatgccgatattgttctggtcataagcaataaggcaggcgttttgggtctagaa
cgagccgcccgctctggtattccctcgctgaccatttctcacaaggatttccccactcga
gaggattatgatgctgaactcacgcgccatttgcaggcagctaatgtggatattgtttgt
ttggccggtttcatgcgagtccttagtgtaccctttgttcgcacttggcggggacgtctc
attaacattcatccatctctgttgcccaaatatccggggctaaatgttcaagctcgggcc
ttggaggcgggtgaaagagaatccggttgcactgtccattttgtggatgaaggtgtcgat
actggagcgattttattgcaggctcctgtacccattttacccaacgacgatgtcgatgca
ttgacccaacgtattcatcaagccgaacattgggccttcccgcgtgcattggctctgctg
gccagtggctccgcacaattgggtccggacggaaagtgcctaagcaaggaccaataa
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