Drosophila yakuba: Dyak_GE17209 Help Entry Dyak_GE17209      CDS       T01068                                  Name (GenBank) uncharacterized protein   KO K10592   E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] Organism dya  Drosophila yakuba Pathway dya04120   Ubiquitin mediated proteolysis dya04137   Mitophagy - animal Brite KEGG Orthology (KO) [BR:dya00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     Dyak_GE17209  09140 Cellular Processes   09141 Transport and catabolism    04137 Mitophagy - animal     Dyak_GE17209  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:dya04121]     Dyak_GE17209 Enzymes [BR:dya01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.26  HECT-type E3 ubiquitin transferase      Dyak_GE17209 Ubiquitin system [BR:dya04121]  Ubiquitin ligases (E3)   HECT type E3    Dyak_GE17209 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HECT DUF913 UBM WWE DUF908 UBA UBA_7 Como_LCP UBA_3 Motif Other DBs NCBI-ProteinID:  EDX01812 UniProt:  B4PWR6 LinkDB All DBs Position X Genome browser AA seq 5111 aa AA seqDB search MKVDTVKLKKGSSELTAECRELIDELTKRRTRAELLEFLDTVHVWIYGKCELYHWIEILD RFDKILEEASRHVNGNEFVLQCDTNFQETDVTLLLHVLNFTTLLIEHSFSRHLYNSIEHL TVLLSSQNMDIVLAVLNLLYMFSKRSNFIPRLPFEKKELLIVKLFNIAERWGDPNYGLSL KDCCIGEPKLEFLYQLCIDYVDEHGHAAQLEIPDMMDLCHTASAPEVIKTIAGQISKPSE AIKMRIAHRVRLISGFNNYKLRLQFVQARLQAVSILIYSNALQDNTDKVLYAGFGEELCE LIDKEDVHLVEIRAAVLRTLTSMLHFDRNPNVPSRAGSRLMKIVHYTGAERQGGTLPLLV RDCIDNLTTHGLTERYPLILATSLFSLLYHLASYEMGGTALVKSGMMQSLLCVISWPGVD LEHITFVTRAVRVIDLITNIDIARFHQNNGLNVFIDRLEKEIKSCCKALADIGITLKEST LRDDHKLDTSLDHVDEDVEDGAGENASVASGSGSPRRENSSDGVSGAGNSAYRAYHEHSG GAGSGAGLLDIGGARSSAGGGASGTSGTAAGLINRDGSAARPPAIMYPTNSYYARPLAER KAELSSQLPSSLAPKKPSCVTQRAALLKSMLNFLKKSIQDHAHFSNMRNIMETSLTQSLR HIIANAEYYGPSLFLLATDVVTVYVFNEPSLLSSLQDLGITSVMLKALLQKDVPATREVL GSLPNVFSALCLNERGLFEFLSYDPFDKVLKVLLSPDYLVAMRRRRSSDPLGDTATNLGN AMDDLIKHHPYLRADATEAIVRLLNELVRLGSDPSFICWRANKESSGSGSGSGSHGSGHH VASTPSPMVMVAGTGGSSSVLQGAADTNDSSGDDDDDDDEMSSASQQQQQPTTPGQSGGA TTPRTQQAGGVVGAGATGAPAAASQAVKVVTPPEREAIPLIDYILNVMKFIEAIFSNSPN GDHCREFVLHGGLKPILQLLSLPNLPVDSPVSTTSQAVANVCKAILSQAQETKVLDVALK QLADIVAQLKPLIKHFTFPGGSVLLAELVCCQRLEDGFANAEYTPILHNMSFVHGYVVML VHLCRNASNDMRAILLKRWGVNRETGVQLLQQLVQLYISLVWESTILLNLCSDEPTQHPD LIWDEIAAQMSAAAGTADPLTEAELSRKLERAAEFRTKYTPEEQFRYIKSLLAASSRLGR ALAELLGTLVKLSVGSPQTRQRRINDLISNINKVPTPEAREIARILSSILVNGFSHESIL PKPVPKLKLTFLICSVGFTGPMLFDDKRSAFHLMISQFCAENGLKAFFEMFYWALSLDNV SQKFEFDQWASMEDLMQSHEDDKRDCPEGTGEFLDAWLQLLEKMVNPRAMLDSPYTMSPR LNYLPDSVPFEPVFYLIHIHQLAMQALRRIWARRPIPNYGPSMFETMILILKHLIKSHQT LLDRYHTRMKEIKFENLYIRSTDDGLNADHIKTLTDMGFMHYHVIEALRTNASLEEATDY LLNNPEASPLSTTGGQSGSSAPPPPPPPSTSTMDIDIDLPADGESTQSKSSTSPNSSYDY KHLKLMPSLIFDRFCDEAISRAFEFMEAIPDTVNSAADLIAVLYRRHNHLNKQVFVTNFV RNIIQWVDFTLQLFEPAKTTGSKASRLEECLTGMTATRLFVRLKTSTLLLEENYSDLHRP LVEAITAQDAMVSLVKLLDCMSQWMLEQSTEANTGQQRATVPRWVQNLVDLIDAIDSISH ILQRKANMRAVSSDVWRWYDASTGKWNAYSEANNELIRNAYAAGERWLHINIGRQRCTVS LNCMTQVSEASGTHRPVCPALKLSEAITSLHNPMAPHKVEHLLNRVVRTAPDGSGTVHND ELISLRQLINITDGQQQQSENSGNPNEEATNEDGPTAASSGSPPATMTTRSKSRQKSAAA AAAAKNKSQSGGSPPIPQAHPEKXXXDSHQMLNETKLSLLRLCARLTRNYDNAQVFIRRG GVRMLLHLQQACSFMGFPTYANIILRHVLEAPPVLQEAMERVLGMRAAGIVPVGHRDLIY VLTQVSSAVSRNPQIFVAAAKEMLKGEYLLNTNSTTLADDARVMVKSKFGQQPTAAAGGA TPTPPPVAKDELKDDPQVQSSVAVLKDLLHGLVQPCWHYGGTGSLDRGQGAAELLQPDQP PGTAQGCHDDEETPAPVSSKKQSSSGGGATAAGQAQATEKFEPCCCTWHIPTSGHTHAKP TISRATLLKLLADSTRAYQSLVPRVLLSHVYTPADSPLISAPQQTFLGVLLDRFLPITQR HHVPEVSTMTRVLICSLSDCYQQPGVQVHVAEELHAAVARALAQPDSAEKHTRLQVLMSL FPNLIESPMLYDKVHMHRNNMYRVLLRQGVMTYLTKVAQYKDLSNHNTLSTLAAILRPME ILLRFSVSTTTLGSKRILFGGGGPGGANASGNGNNTAGGSNGNGPGSGNTYGTIINRRLY PRLAARTGVSSAVERSNAMGGEHVLRDIIRNVLSDRRHAFEFIFNSDDMAVDSEDSAAPG SGVGGSGGSGTGSVGGGVSGSGSGGSTAAVIDVVEERSNGGDTNDPPANVSSASSAAGQS SASGGPVRPVVNFDQLWDDFLQSEGLRLASRSGGGAGSGSGSVGASSTGQQNGSNTTASS TNSGNNSGSGDPRLRTNPDVDVGSGNGSGSGSNAGVVNDNGISGGGGSDGASTSSDTGAP GGARDLNASLLGDVSTSDSDSDASTENDERNEEDEDEDDDAPDEDVDEHSETDVDEERPR QFIEVFDHIYEPESSETASNDADVDNDDDDDEDEDDVDDDDDDDEDNDDEDREEGQSVMD AELENQIDIALAMVSSNNRPRRSAAVNASGDGSASRPNPDDEVDDEDDDVDADPDGDPDV DPIGGPSAAQAEAYLYERLGSGLMPTPPVGFRVRMNSSIAQPLDIDVNGGNAGSGSNAGV TGSAGGSGRGSSTGGTTASIGAIASAALRPSSGSWMAPDFNFIRISGMDSSMGSGASVAG NANGNEVNVFLTPSMSLERTGGASGSGQTMSELLNEQPSVAGGGGGGGSNSGGGGVSGVG ANGGTTGQHPNATLCTNGVRRRLLYLDQQYCVCMPTHQNPTEETQMETFTQDALHWWLEE ATLLDMESQTDACLYAAHFLLPHLIKELKTAHQQRKQEEAARQLATNATTPASVSSGTTT SSNTTSAAGTANPTATASIASSILANAGTAGSGSSSMVVPPVAASATGGTRRSSIPVLIP SMFGPNATSATANSASSDATATTGGPARLFSSIDNSGSLETQSTTRSPRQRGGLRQHSQL PFNIYAEIDLTNEQDSESATSTSTTTGTSADGAESQPQQNTSSSAAQVPVLQHQRHPPVP LLPSSGRPSRPHSRLDEAELLLLQLADRQIRNRLQGSSGHTNSSRTSGSALINARPNRDL PACLQRLEHPPGSIFHRPSANRTPAPTLVSMPTPMSSAALEQLNVTAPDVVGTDRNFALP PSLEVDVDVLPGILDMPQQEAQPEDDQLLLPPPPPPPPSDTTPLVLTEDDLWPGTVVNAG NREESSVSAVATDSTESANESNQQEATPESSESTSPNPPAPSAEPTLLESGAAEDTSAST QPPASTEESASTGAASGGASGTTATITDMSPEVRAALGDLEVPEGVDPSFLAALPSEMRE EVIQEHLRMQRIRQRAQQNAIQIAHDSLVEVNPEFLAALPLNIQSEVLMQQRIEQQRQAA QTANPEDPVDTAAFFQNLPENLRQAILTDMEESQIASLPPELAAEAQFLRRDWESRNGAR MDAHPPSNALSRFQTTLQSLDEARWHSSIWYDASGNAQPQHHQHTTIVHHHAHAHHAPTM GKPLALLMMEDENILLDPDSLATLLLFLFVEDQKVNSMRLHRVIRNLCHHEPTRDWIISA LISIIQKTNEDNANFGAGQAGGKPEWLKLRVDAAFGYKSNIFLINRLYEGSARSISINPQ AAQMIVRNCLDLLFVLAKHYPSSFVPYNREVKARRILSAVFGMPSPTAGSGGATGSGSAA TGGLTAYDEVPPGGTLDFRSRFCRYQVANRLRGILDDHPAPKPSAPLDEAPSTSKAAAAK AAATAKVSTASQNQHSVPYQTNAKNFWDVVLNIDRQTQVRLANVAQFPLTSQPAWEWQAN TADFLSFSDSPFGQLLEMLPYKVICRSPHLTDMLVKLLASLSTELPKEEEQLPLSDQMPT LIPIGQVAGAAAAAPAENTQPIATEIGDGVAANIEEQAAPASGNPASGDSNAGAKRTQLP TLSVALPVTPSKPRRKIYSKNFSQLQLVIEVLTHQCGTTEGLDNVAKLIVNLTQCSQASN AIFIQYLTAAILGLAEEVRQAIQMLLNEIRMYNIHHGVAGTTSQAASTSGAAAATAGYQP TVSGASLLPNLAVHEGIMQDRFTAEHVIISAPKNAKPTCELQLPSMKKLMSNSSAQPYFL RTLKIFMQVRDMYEAQNSLSTGGGVAGAAGDNDDDIIDIEGDGGASGGSSSDMAPGSAST ISPPPPMETNQTAQDVDDDEEEDDEVRASPGVGNHAAASASKSTKPTLSQILCLDVLWHT LSECLVALEESKDEFAVLVLQPTVEAFFLIHASHRGVTKKSGRGSLPGAVGSGLRAAAGG GIGGLGAAAASAQEYSPSMDDASSANTLSSASFDDEPRMQDASTNTPLSANASGNTALSA HEAQLRQDRQKFLQFAEKHRTVLNQILRQSPTHLSDGPFAVLVDHTRILDFDVKRKYFQT ELERLDEGIRREEHTVSVRRVTVFEDSFRVLYRLGPEEWKNRFYIVFEDEEGQDAGGLLR EWYVIISREIFNPMYALFCVSPGDRVTYMINPSSHANPNHLSYFKFVGRVIAKAVHDNKL LECYFTRSFYKHILGKQVKHTDMESQDYEFYKGLDYLMKNDISTLGYELTFSTEVQEFGV TQIRDLKPNGRDTAVTEENKFEYVQLVCQLKMSGSIRQQLDAFLEGFYDIIPKHLISIFN EQELELLISGLPDIDIEDLKANTEYHKYTSKSAQIQWFWRALRSFDQADRAKFLQFVTGT SKVPLQGFGSLEGMNGIQKFQIHRDDRSTDRLPCAHTCFNQLDLPMYKSYDKLRNCLLKA IHECSEGFGFA NT seq 15336 nt NT seq  +upstreamnt  +downstreamnt atgaaggtggatacggtgaagctgaagaagggctcctcagagctaacggccgagtgccgc gagctcatagatgagctgactaagcgacgaacgcgggccgagctccttgagttcctcgac accgtccacgtctggatctatgggaagtgcgagctgtatcactggatcgagattctcgat aggttcgacaagatcctcgaggaggcatcgcgccatgtcaacggcaacgagtttgtgctg cagtgtgacaccaacttccaggaaacggatgtcacactgctactgcacgtactcaacttt accacactgctgatcgagcactcgttttcacgtcacctgtacaactccatcgaacatctg acggtgctgctctcctctcagaacatggacattgtcctggccgtcctcaacctgctctac atgttttccaagcgcagcaattttataccccgcctgccgttcgagaagaaggagctactg atcgtcaaactcttcaacatagccgagcgctggggcgatcctaattacggcctgtcgctc aaggactgctgcattggcgagccaaagctggaattcctctaccagctgtgcatcgactat gtggacgagcacggtcacgccgcccagctagaaatccctgacatgatggacctctgccac acggcatcagctcccgaggtgatcaaaacgattgccggacagatctcaaagcccagtgag gcaatcaagatgcgcattgcccatcgggtgcgcttgatctcaggcttcaacaactacaaa ctgcgacttcagtttgtccaggcgcggctacaggctgtctctattctgatctactcaaat gccctgcaggacaacacggacaaggtgttatatgccggctttggcgaagagctgtgcgag ctgattgacaaagaggacgtgcatctcgtagagataagggcggctgtgctccgtacactc acatcgatgctacacttcgaccgcaatccgaatgtgccaagcagggccgggtcgcgcctg atgaagatcgttcactacacaggagcagagcggcagggcgggacgctgccgctgctggtt cgtgactgcatcgataatctaaccacccacggactaaccgagcgttacccgctcatcttg gccacctcactattctctttgctgtatcacctggcgagctatgaaatgggcggcactgct cttgttaaaagcggcatgatgcaatccctgctgtgcgttatcagctggccaggagtcgat cttgagcacatcacgttcgtgacgcgggcagtgcgtgtgatcgatctgatcaccaacatc gatatcgcccgctttcaccagaacaacggacttaacgtgttcattgaccgcctggagaag gagataaagagctgctgcaaggcattggctgacatcggcatcacgctgaaggagtcgaca ctacgcgacgatcacaagttggacacctcgctggaccacgttgacgaggatgtggaagat ggtgctggtgagaacgcatccgtggccagtggaagtggatcgccgcgtcgcgagaactcc agtgacggcgtcagtggtgccggcaacagcgcatacagagcttaccatgagcatagtggt ggagctggctcaggagcgggactcctggacattggcggagcacgcagctcggcaggcggg ggagcatcaggtacatccggaacggctgcgggattaatcaacagagatgggagtgctgct cgcccgccggctattatgtatccaacaaatagctactacgcccgtccactggccgaacgc aaggcggagctctcttcgcagctgccgagcagcctagcgccgaagaagccgtcctgcgtc acccagcgagccgcgcttcttaagtcaatgctgaacttcctgaagaagagcatccaggac catgcccactttagcaacatgcgaaacatcatggagactagtctgacccaatcgctgcgc cacatcatcgccaatgcagaatactacggaccctcgctgtttctcctggccaccgatgtg gttactgtgtacgtgtttaacgaaccatcgctgctatcttcgctgcaggatctgggcatc accagtgtcatgctaaaggcgctgctccagaaggatgtgccagcaactcgggaggtgttg ggatccctccccaacgtattttccgccttgtgcctaaatgagcgcggattgttcgagttc ctttcctacgatccgtttgataaggtgctgaaggtgctgctttcgccggactacttggtg gccatgcgacggcgccgctcctctgatccgctgggcgatacagcaaccaacttgggcaat gccatggatgatctgatcaaacaccatccctacttgcgggctgatgccacagaggcgatt gtcaggctgttaaacgagctagttcgccttggctctgatcccagcttcatttgctggcgg gcgaacaaggaaagcagcggctctggctccggttccgggagccatggcagtggccatcac gtggcctcaacaccatcgcccatggtcatggtagctggcacgggaggatcttcatcggtc ctgcagggtgcagcggatacaaacgatagcagcggagatgacgacgatgatgatgacgaa atgagctccgcatcacagcaacagcagcagcccacgacaccgggtcaaagtggaggagca accacacccagaacacaacaggcgggaggggttgttggagctggagctacaggtgcgccg gcagcagcatcgcaagccgttaaagtggtgaccccaccagagcgagaggccatccctctc attgactacatcctcaatgtgatgaagtttattgaggcgatattcagcaacagtcctaac ggcgatcactgtcgcgagtttgttctccatgggggattgaagcccatcctgcagctgctg tcgctgcccaatcttccagtggattcgccggtgtccaccacctcccaagcggtggccaat gtgtgcaaggccatactcagccaggcacaagaaaccaaagtgctggatgtagcactcaag cagctggcggacattgtggcccagctgaagccactgatcaagcacttcacttttcccggc ggcagtgtcctgctggcggaactagtctgctgccagcgtctggaggatggctttgccaac gccgaatataccccaattctgcacaacatgagttttgtgcacggctacgtagtgatgctt gtgcatctttgccgaaacgcctccaacgacatgcgagccattcttctgaagcggtggggt gtcaatcgggagaccggagtccaattgctgcagcagctcgtccagctgtatatctcactg gtgtgggagagcacaatcctgctgaatctttgttccgatgaacccacccagcatccggat cttatctgggatgagatcgcagcgcaaatgtcagcggcagctggtactgcggatccccta accgaggcagagctctcgaggaaactggaacgcgctgcggaattccgtacaaagtataca ccagaggagcagttccgatacatcaaatccctgctggcagcgagctcccgattgggaaga gctcttgctgagctactgggcacattggtgaaactgtcggtgggatcaccacaaacacgg cagcgtcgcatcaacgatctgatcagtaatatcaacaaagttcctacaccagaagcgcgc gaaatagcccgcatcctcagctcgatcctggtgaacggatttagtcacgagagcattctg cccaagcctgtgccgaaactaaagcttaccttcctcatttgctcggtgggattcacgggt ccaatgctgttcgacgacaagcgtagcgccttccatttaatgatatcgcaattctgcgct gagaacggactaaaggctttctttgagatgttctattgggccctgtcgctggataatgta tcccagaaattcgagttcgatcagtgggcttccatggaggacttaatgcaatcccatgag gatgacaaacgtgattgcccggagggcacaggtgagtttctcgatgcttggctgcagctg ctcgagaagatggtgaatcctcgagccatgttggactcgccgtacacgatgagtccccgt ctgaattacctgcccgactcggttccatttgagccggtcttctacctaatacacatccac cagctagctatgcaagcactgcgcagaatctgggcacgacgcccgattcccaactatgga ccgagcatgtttgagaccatgattctcatcctaaagcatttgattaagtcacaccagacg ttgcttgatcgctatcacactcgaatgaaggagatcaaattcgagaacctgtacatccgg agcacagatgatggattgaatgcggatcacatcaagacgctgacggacatgggcttcatg cactatcatgtcatcgaagcgttgaggacaaatgcgtctttggaggaggccaccgattac ctgctgaacaacccagaggcaagtcctctatcgacgactggtggtcagtcgggcagctcc gctccaccgccgccgccaccgccatcgacttcgacaatggacattgacattgatctgccc gcggatggggagtcgacgcaaagcaaatcctccacttcgcccaactctagctatgactac aagcaccttaaattgatgccgtcgctcatctttgatcgcttttgcgacgaagccatctcg agggcctttgagttcatggaggcaataccggatacggtcaacagtgctgcggatttgatt gccgtgctgtacagacgccacaatcacctcaacaagcaggtattcgtcaccaactttgtg cgcaacatcatacagtgggtggacttcacattgcaactgttcgaaccagccaagacaacc ggatcgaaggcctcacgcctagaggaatgcctaactggaatgacagccaccaggctgttt gtacggctcaagacgtcgacgctgctgcttgaggagaactacagtgatctacatcggccg ctggtggaggcaataaccgcccaggacgccatggtgtcactggtcaagctgctggactgc atgagccagtggatgttggaacaatcgaccgaagcgaataccggccagcagcgtgcgacg gtgccgcgttgggtgcaaaatctggtggatctaatcgatgccattgatagcatcagtcac atcctgcagcgcaaggccaacatgcgagcagtaagcagcgatgtgtggcgctggtacgat gcctccacaggcaagtggaatgcctactcggaggccaacaacgaactcatccggaatgcc tatgcggccggtgaacgctggctgcacatcaacattggacgccagcggtgcaccgtgagc ctgaactgcatgacgcaggtgagcgaagcatccggaacacatcgacctgtctgcccggcc ctgaaacttagcgaggccattacctctctgcacaatccgatggcgcctcacaaggtagag catctgcttaatcgcgttgtgcgcactgcacccgacggatcaggaactgtgcataacgat gagctgatttcactgcgccagcttattaacattaccgatggccagcaacaacagtcggag aattcaggaaatcccaacgaggaggcgacaaatgaagacggcccaacagcagccagtagc ggatcaccgcctgccacaatgacgacgcgcagtaagtcgcggcagaagagcgcggcggct gctgcagctgccaagaacaagtctcagtcgggtggttcgccacccataccccaagcgcac ccagaaaaannnnnnnnggattcgcatcagatgcttaacgagacgaagctttcgctgctc cgtctctgtgcgagactgacgcggaactacgataatgctcaggtgttcattcggcgtggc ggagtgcgaatgctgctgcacctccagcaggcatgcagtttcatgggtttccctacctat gcgaacatcattctgcgtcacgttctagaggctccgcccgtgctccaggaggccatggaa cgcgtgctgggcatgcgagcagccgggatagtgcctgtgggtcatcgcgaccttatctac gtgctcacccaggtgtcatcggcggtgtcgcgtaatccgcagattttcgtggctgccgcc aaggaaatgctaaagggagagtatctgctgaacacgaacagcacaacgctggcagacgat gcccgtgtcatggtcaagtccaagtttggccagcaaccgacggcggcagctggcggtgcc acgcccacaccaccaccagtggccaaggatgagctgaaagacgatcctcaggtgcagtca tcggtggccgtgctcaaggatctgttgcatggactggtgcagccgtgttggcactacggc ggcactggatcattggatcgcggtcagggcgctgcggagctactgcagccggatcagcca ccagggacggcgcagggatgccatgatgatgaggaaacccccgcacccgtgtccagcaag aagcaatcctccagcggcggaggtgctacagctgctggccaagctcaggcgacagaaaag ttcgagccatgctgttgcacctggcacataccgaccagcggacacacccatgccaagccg accatctcgagggcaactttgctgaaactgctggcggattcaacccgggcctaccagtcg ctggtgccgcgtgtcctcttgtcccatgtttacacaccggcggacagtcccttgatctcc gcaccgcaacagacgttcctgggcgttctccttgatcgcttcctgcccataacccaacgg catcatgtgcccgaggtcagcacaatgacccgcgtactgatatgctccctatcggattgc taccagcagcccggagtccaggtgcatgtagctgaggagctgcacgccgcggtcgccaga gccctggcccagccggattcggccgagaagcacacgagactgcaggtcttgatgagcctc tttcccaatctcatcgagtcaccaatgctgtacgacaaggtgcacatgcaccgcaacaat atgtaccgggtgctcctacgccagggcgtgatgacctatctgacgaaagtcgcccagtac aaggatctgtccaaccacaatacgctgagcacccttgcggccattctgcgccccatggag atccttctgagattcagtgtgtccaccacaacgctgggctcgaagaggattctctttggc ggtggcggccctggcggagcgaatgcatctggcaatggcaacaacactgccggcggcagc aatggcaacggaccaggatctggcaacacctacggcaccattattaaccggcgactatac cctcgtctggcggcacgcactggtgtcagttctgctgtggagcgttccaacgctatgggt ggagagcatgttctgcgagatatcatacgaaatgtactgtcggatcggcgacatgccttc gagttcatctttaactcggacgatatggctgtggactctgaggactcagctgctccagga tctggagtgggtggaagtggtggctctggaacgggtagtgtcggaggaggcgtgtcggga tcaggatcaggtggcagtaccgcagccgttatcgacgtagtcgaggagcgtagcaatggc ggagataccaatgatcctccggcaaacgtgagctctgcatcctctgctgcaggacaatca tcggccagtggaggtccagtgcgtccagtggtcaactttgatcaattgtgggacgatttc ttgcagagcgagggactgcgtctggcttcacgaagcggcggtggcgccggatcgggcagt ggatccgttggagcaagctcaaccgggcagcaaaacggaagcaacaccacagccagttcc accaactcaggaaacaattccggcagcggagatcctcgcttgcgcaccaatcccgatgtt gatgtaggcagtggcaatggtagcggcagcgggtccaacgcaggtgtcgtgaatgataat ggaatcagcggcggtggcggaagtgatggtgcgtccacctcatcagacacgggagctcca ggtggtgctcgcgatttgaatgcctcactgctgggtgatgtcagtacctccgattcggac tcggatgcttccacagagaacgacgagcgaaatgaggaggacgaagatgaggatgatgac gctcccgatgaggatgtggatgagcacagcgagacagatgtggacgaagagcgaccgcgc cagttcatcgaggtctttgatcacatctatgagccggaatcctctgaaaccgcgtccaac gatgcagatgtggataacgatgatgatgatgacgaggatgaggacgatgtggacgacgac gatgatgatgacgaagacaacgacgatgaggatcgggaggagggtcagagtgtcatggat gcggagctggagaaccaaatcgacatcgccctcgccatggtgtcctcaaacaatcgtccc agacgcagtgcagcggttaatgcttctggcgatggttccgccagtcgacccaatcccgac gacgaggtggatgatgaggatgacgatgtggatgctgatcccgatggagatcctgacgtg gatccaattggcggaccatcggccgcccaggcggaggcctatctgtacgagcgattgggc agcggtttaatgccaacaccaccggttggtttccgtgtacgaatgaacagctccattgcc caacctcttgacattgatgtgaatggcggaaatgctggtagtggaagcaatgcaggagtg acaggatcagccggtggctctggccgaggatcttctacgggcggaacaacagctagtatt ggagcaattgcctcagccgcattgcgtccatcatctggttcgtggatggcaccggacttt aactttattagaatttcgggcatggatagttccatgggcagcggagcatctgttgctggg aacgccaacggaaatgaggtgaacgtcttcctgacaccctccatgtcactagagcgcact ggtggtgcatctggcagcggccagaccatgagtgagctgctaaacgaacaaccatcggtg gctggcggaggtggtggcggaggatcaaactccggcggaggtggcgtcagcggggtcggt gcaaacggtggcaccacaggacagcatccgaatgcaacgctctgcacgaacggagtgcgg cgtcgattgctatatctggaccagcagtactgtgtgtgcatgcccacgcatcagaacccc actgaagagacccagatggagactttcactcaggatgctctccactggtggctagaagag gccacgctcctggacatggaaagccagacggacgcctgtctatatgccgctcattttctg ctgccgcatctcatcaaggagctgaaaacagcgcatcagcaacgcaagcaggaggaggcc gcccgccaattggccaccaatgccacaacaccggcgtccgtctccagtggaactacaaca tcctctaacacaacgtcagctgcgggcacggcaaaccccacagcgacagcatcgattgcg tccagtatactggcgaacgccggtactgctggctcaggaagcagcagcatggtagtgcca ccagtggcagcctctgccacgggcggcacccgccgcagttcgattcctgtgctgattccg tcaatgtttggtcctaacgcgacaagtgcaacggcaaatagtgccagtagcgatgccacg gccacaacgggcggaccagcgaggcttttctcgtccattgacaacagtggctccttggag acgcaatcgacaacgcgatcgcctcgccaacgcggtggattgcgccagcatagtcagctg ccttttaacatttacgctgagattgacctaaccaacgaacaggatagcgaaagcgcaacg tccaccagcacgacaacagggacatcagctgatggagctgaatcacagccacagcagaac acctcctcttcggcggcacaggtgccggtgctacagcatcagcgccatccaccggtgcca ctcctgccgtccagcggaagaccatcgcgacctcactcgcgtctcgatgaggcagagctg ctcctgttgcagttggccgatcgccagatacgcaatcgcttgcaaggatccagtggacac acaaattcctcgcggacttcaggctcggcgctaattaacgctcggcccaatcgcgaccta cccgcctgtctgcagcgtcttgagcatccgcccggctccattttccaccgacccagtgcg aacagaacgccagctccgacgcttgtgtccatgccgacgccaatgtctagtgcggctctg gagcagctaaatgtcaccgctccggatgttgtgggaacagacagaaactttgccttgcca ccttcccttgaagttgatgttgatgtgctgcctggcattctcgacatgccgcagcaggaa gcacaaccagaagacgatcagttgttgctgccaccacctccgccgccaccgcccagtgat acgacgccattggtcttaacagaagacgacctgtggcctggaacggtggttaatgctggc aatagagaagagtcgtccgtttcagcggtagccacagacagcacagagtctgccaacgag tcaaaccaacaggaagcgacgccagaaagcagtgaatctacttctccaaatccgccggca ccttcagcagaaccaacgctattggaatcaggcgctgcagaagatacctcagcaagtaca caaccgccagcatcaacagaagagtccgcctctactggggcagcgtctggtggagcgagc ggaacaacagccaccataacggacatgagtcccgaggtgcgggctgctctaggggatcta gaggtgcccgagggcgtggatccctccttcctggccgctctgcctagcgagatgcgcgag gaggttatccaagagcacctgcgcatgcagcgcatccgtcagcgagcgcagcagaatgcc atccaaattgcccatgactcgctggtcgaggtcaaccctgaattcctcgccgccctgcca ctaaacatacagtcggaggtgctgatgcagcagcgcatcgaacagcagcgacaggccgct cagactgccaatccggaggatcccgttgacacagctgctttcttccaaaacctgccagag aatctgcgccaagcgattcttaccgacatggaggagtcgcagatagccagtttgccgccg gagttggctgccgaggcgcagttcctgcgtcgcgactgggaatctcgcaacggtgcccgc atggatgctcatccgcccagcaatgccttatcccggttccagacaacgctccagagcctg gacgaggcacgctggcacagctccatttggtatgatgctagtggcaatgcacagccgcaa caccatcagcatactacgattgtgcatcaccatgcccacgcacatcatgccccaaccatg ggcaaaccactggcattgctgatgatggaggacgagaacattctgctcgatccggattcg ttggccacacttttgctcttcctgttcgtcgaggaccagaaggtaaacagcatgcgactg catcgcgtcatccgcaacctttgccaccacgaacccacccgggactggatcattagcgcc ctgatcagcataatccagaagaccaacgaggacaacgcgaacttcggtgcgggtcaagcg ggtggcaagccggagtggctgaagctgcgtgtggacgctgcctttggctataagagcaac atattcctcattaaccgattgtatgagggcagtgcccggagcatcagcatcaatccacag gcggcacagatgatagtgcgcaactgtctcgacctgctgttcgtgctagccaagcactat ccgtccagctttgtgccctataatcgtgaggtgaaggccaggcgaatattgagtgcggta ttcggcatgccatcgcccacggccggatcaggaggagccacaggatctggatctgcagcg actggcggtttgaccgcttacgatgaagtaccacctggtggaactttggacttccgttca agattctgtcgctatcaggtggccaatcggctacgtggcatactcgacgatcatcctgcc ccgaaaccctcagcgcccttggatgaggcaccctccacatcgaaggcggcggcggcaaag gcagctgccacggccaaagtgtccactgctagccagaatcagcactcggtaccgtaccaa accaacgccaagaacttctgggatgttgtgctgaacatcgatcgacagacacaagtgcga ttagccaatgtggcccagtttccgctaacctcgcagccggcgtgggaatggcaggcgaat accgcggacttcctctcgttcagcgactcacccttcggccagttgctggaaatgcttccc tataaggttatatgccgatcgccccatcttaccgatatgctggtcaagctgctcgcctcg ctcagtacagagttgcccaaggaggaggagcagttgccactcagcgatcaaatgcccaca ctgatacccattggccaggtggcgggagcggcggcggcggcaccagccgagaatacccag cccatagcaacggaaattggtgacggtgtggccgccaacattgaggagcaggctgctccg gccagcggtaatcctgcctccggtgatagcaatgcgggagcgaagcgaacccagctgcca actttaagtgtggccctgccggtgacgccatcgaaaccgcgtcgcaagatctactctaag aacttttcgcagctacagctggtcattgaggtgctgacccaccagtgcggcaccaccgag ggtctggacaacgtagctaagctgattgtgaatttgacgcagtgctcgcaggcatctaat gccattttcattcagtacttgaccgctgcgatattgggattggccgaggaggtgcgtcaa gcgatacagatgctgctcaacgagattcgcatgtacaacattcaccacggcgtggccggc accacctcacaagctgcgtccacttctggggcagctgcagcaacagctggataccaaccc acagtgtccggagccagtctcttgccaaacttggccgtgcacgagggcataatgcaagat cgcttcaccgccgagcacgtgatcatctcggcaccaaagaatgccaagcccacctgcgag ttgcaactgccgtcgatgaagaaacttatgtcgaactcgtccgcccagccgtacttcctg cgaaccttgaagatcttcatgcaggtacgcgacatgtatgaggcgcagaatagtttgtcc actggcggtggagtcgctggtgctgccggcgacaacgacgacgatatcatcgatattgag ggtgatggaggtgcgtccggcggtagcagttcggacatggctcccggatctgccagcaca atatctcctccgccacccatggaaaccaatcagaccgcacaagatgttgatgatgacgag gaggaagacgatgaggtaagagcttccccgggagttggcaatcatgcagcggcaagtgct agcaagtcgaccaagcctactctgagtcagatcctctgcctggacgtgctgtggcacacg ctcagcgagtgcctggtggcgttggaggagtccaaggacgagttcgccgtcctggtgttg cagccgaccgtggaggccttcttcctcatccacgcctcgcatcgcggtgtgaccaagaag tcgggtcgcggctccctacctggagctgtgggctctggactgcgagcagctgctggcggt ggaatcggaggactgggagcagccgcagcgtctgcccaggagtacagtccctcgatggat gatgccagcagcgccaacaccctcagttcggctagtttcgatgatgagccgcgaatgcag gatgcatccacaaacacgccgctttcggcgaacgcctccggcaacacagcgctgagcgcg cacgaggcgcagctgaggcaggaccgtcaaaaattcctgcaattcgcagagaagcaccgc accgttcttaatcagatactacgccaatcaccaactcatctctccgacgggccgtttgcc gtacttgtcgaccacacgcgcatcctggactttgacgtcaagcgcaagtacttccagacg gagctggagcgactggacgagggcatccggcgtgaggagcacacggttagtgttcgtcgc gtaaccgtttttgaggactcgttccgtgtcctgtaccgcctggggccggaggagtggaag aaccgcttctacatcgtatttgaggatgaggaaggccaggacgctggcggcctgttgcgc gagtggtatgtgatcatatcccgcgagatctttaatccgatgtatgccttgttctgcgta tcgccgggcgatcgcgtcacctacatgataaatccatccagccatgcaaaccccaatcac ttaagctacttcaagtttgtcggccgcgtaatcgccaaggctgtgcacgacaacaaattg ctggagtgctacttcactagatcgttttacaagcacatcctgggcaaacaggtgaagcac acggacatggagtcgcaggactacgagttctacaagggcctcgattatctcatgaagaac gacatctccactctgggctacgagctgaccttctccaccgaggtgcaggagttcggcgtc acccagatccgggatctcaagccaaacggacgcgacaccgccgtgaccgaagaaaacaag tttgagtatgtgcagctagtgtgccagcttaagatgagcggctccatcagacagcaactg gacgcattccttgaaggcttctacgacattattccaaagcatttaatttcgatattcaac gaacaagaactggaacttctcatatccggcctgccggatattgacattgaagatctaaaa gcgaacaccgagtaccacaagtacacctctaaatcggcccagattcaatggttctggcgt gcactgcgcagctttgaccaagcggaccgtgccaagttcctgcaattcgtcactggcaca tcgaaggtgccgctgcagggcttcggctcactggagggcatgaacgggattcaaaagttc caaatccatcgggacgatcgatccactgatcggttgccctgtgcacatacctgcttcaac caactggatctgcccatgtacaagtcatacgacaaactgcggaactgcctgctgaaggct atacacgagtgctctgagggctttggcttcgcctaa

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