Dickeya zeae: W909_17310
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Entry
W909_17310 CDS
T03567
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
dzc
Dickeya zeae
Pathway
dzc00260
Glycine, serine and threonine metabolism
dzc00261
Monobactam biosynthesis
dzc00270
Cysteine and methionine metabolism
dzc00300
Lysine biosynthesis
dzc01100
Metabolic pathways
dzc01110
Biosynthesis of secondary metabolites
dzc01120
Microbial metabolism in diverse environments
dzc01230
Biosynthesis of amino acids
Module
dzc_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
dzc_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
dzc_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
dzc00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
W909_17310 (thrA)
00270 Cysteine and methionine metabolism
W909_17310 (thrA)
00300 Lysine biosynthesis
W909_17310 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
W909_17310 (thrA)
Enzymes [BR:
dzc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
W909_17310 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
W909_17310 (thrA)
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Paralog
GFIT
Motif
Pfam:
AA_kinase
Homoserine_dh
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AJC67736
LinkDB
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Position
complement(3801038..3803494)
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AA seq
818 aa
AA seq
DB search
MRVLKFGGTSVANAERFARVADIIESNARQGQVATVLSAPAKITNHLVAMIEKTVAKQDI
QPNIIEAEVIFADLLQGLAQSQPGFAYDRLKARVDEEFAQLKQVLHGIALLGQCPDSVNA
GIICRGEKLSIAIMEAVFQARGYQVSVIDPVRSLLAQGHYLESTVDIAESTRRISDLVIP
ANHVILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTENPQAPGTLIGLESD
DIRYPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVSQNELSRARKTLEDEFYLELKEGVLEPLDVVQRLAIISVVGDGMRTLRGLSARLFTAL
ASANINIVAIAQGSSERSISVVVNNDVATTGVRVAHQMLFNTNQTLDVFVIGVGGVGGAL
LEQIQRQQSWLKQKHIDVRVCGIANSKAMLTNVHGIPMDRWRDELARAREPFSPAALSRL
VKEYHLLNPVIIDCTSSQVVADQYADFLADGFHVVTPNKKANTGSLRYYHQLRQVAAKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELIRFNGILSGSLSFIFGKLDEGMPLSAATLLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYELELEDIQVDSVLPAEYTQGDVASFLER
LPQLDAEFAHRVEAARAEGKVLRYVGKIEDGKCQVTISAVGGNDPLFKVKDGENALAFYS
RYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKVGV
NT seq
2457 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaaatttggcgggacctcggtagccaacgcggagcggtttgcgcgtgtt
gccgatatcatcgaaagtaatgcacgacagggacaggtcgcgacggtgctgtcagcaccg
gcgaaaatcaccaaccatttggtcgccatgattgaaaaaaccgtggcgaaacaggacatc
cagccaaatatcatcgaagcagaagtcatttttgccgatttattgcagggactggcccaa
tcccagcccggttttgcttatgaccgactgaaagcgcgggtagatgaagagttcgcccag
ctcaaacaagtattacacggcatcgcgttgctggggcagtgcccggatagcgtcaacgca
ggtattatctgtcggggtgaaaaactctccatcgcgattatggaagcggtatttcaggcg
cgtggctatcaggtgtcagtcatcgatccagttcgtagtctgttggcgcagggtcactat
ctggagtctacggttgatatcgctgaatcgacccgccgtattagtgacctggtgatcccg
gcgaaccatgtgatcctgatggcaggctttaccgccggtaatgataaaggcgagctggtg
gtgctgggccgcaatggttctgactactcggcggcggtgctggcagcatgtctgcgtgcc
gattgctgtgagatctggacggatgttgacggcgtgtacacctgtgacccgcgtcaggtg
cctgacgcgcgattgttgaagtcgatgtcctatcaggaagcgatggaattatcctacttc
ggcgccaaagttctccacccccgcactatcgctcctatcgcccagttccaaatcccctgc
cttatcaagaataccgaaaaccctcaggccccgggtacactcatcgggctggaaagcgac
gatatccgctatccggtcaagggcatcaccaacctcaataacatggcgatgatcaacgtt
tccggccccggcatgaaagggatggtcgggatggctgcacgtgtgtttgccgtgatgtcg
cgtgccggtatttcggtggtactgattacccaatcctcttctgaatacagcatcagcttc
tgtgtatctcaaaatgagctgtcgcgtgcgcgcaaaacgctggaagacgaattctatctg
gaactgaaagagggtgtgctggagccgctggatgtggtgcagcgactggcgattatttcc
gtggtgggtgacggtatgcgtacgctgcgcggcttgtcggcgcgtttgtttaccgcgctg
gcgagcgccaatatcaacatcgtggcaatcgcgcaggggtcgtccgaacgctcaatctcg
gttgtcgtgaataacgacgtggcgaccacaggtgtgcgggtagcgcaccagatgctgttt
aacaccaatcagacgctggatgtctttgtgattggtgtgggcggtgtaggcggcgcgctg
ctggagcaaatccagcgccagcagtcatggctcaaacaaaaacacattgatgtgcgggtg
tgcggcatcgccaattccaaagcaatgctcaccaacgtgcacggtattccgatggaccgc
tggcgtgacgaactggcgcgtgcgcgtgagccattcagcccggccgcgctcagccgtctg
gtgaaagagtatcacctgctcaacccggtgatcatcgattgtacgtccagtcaggtcgtg
gccgatcaatatgccgattttctggcagacggtttccatgtcgttacgccgaataagaaa
gccaacaccggctcactgcgttactaccaccagttgcggcaggttgcggcgaaatcacgt
cgcaaattcctgtatgacaccaacgttggcgcaggtttgccggttatcgaaaacctgcaa
aatctgctgaatgccggtgatgagctcatccgcttcaacggtattttgtcgggttcttta
tcctttattttcggcaagctggatgaaggcatgccgttgtccgccgcaacgctgctggcg
aaagaaaaaggctttaccgaaccggacccgcgtgacgatctgtctggtatggatgtggcg
cgtaagctgttgatcctggcgcgtgaggcggggtatgagctggaactggaagatatccag
gttgattctgtgctgcccgcggaatacacacagggcgatgtagccagttttctggaacgt
ttaccgcagttggatgccgaatttgcccaccgggttgaagccgcgcgtgcagaaggtaaa
gtgttacgctacgtcggtaagatcgaagacggcaaatgtcaggtgacgatcagtgccgta
ggcggtaacgatccgttgttcaaagtgaaggacggtgagaatgcgctggcgttttacagc
cgctactatcagccgctgccgctggtgttgcgaggatacggggcaggtaatgatgtgacg
gcggccggggtatttgcagacctgctgcgtacgctgtcgtggaaggtgggagtgtga
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