Endosymbiont of Acanthamoeba sp. UWC8: I862_03970
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Entry
I862_03970 CDS
T03255
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eaa
Endosymbiont of Acanthamoeba sp. UWC8
Pathway
eaa00300
Lysine biosynthesis
eaa00550
Peptidoglycan biosynthesis
eaa01100
Metabolic pathways
eaa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eaa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
I862_03970
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
I862_03970
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
I862_03970
Enzymes [BR:
eaa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
I862_03970
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
FabD_helical_ins
Motif
Other DBs
NCBI-ProteinID:
AIF81354
UniProt:
A0A075MPZ4
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Position
complement(817413..818831)
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AA seq
472 aa
AA seq
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MNSSLADKAHEKFQGEEKIIWNKASLEQALGCEVRASFSACGVSINSRTIRRGEIFIAIK
GENFDGNDFAFDALEKGASLAIVSGADNNLLHDNKKVVVVKDTMVALTKMAKFARSRIKG
KVIGVTGSVGKTSAKEMLKLALENQGNVFATEGSYNNHIGLPLSLAKLPEDSDYAIIEMG
MNHAGELADLTVLAIPDIAVITNVEAVHLEFFKSVSAIADAKSEIFNSMQAGGFAIINFD
NPYHQILVSKAHNKQLNVVGFSETQKTPARLISYKLEKGISHIKAELFGREYEYTINAPG
KHLAYNSIAVLAATKIAGAEVDCAAYNLSKFHSVKGRGEIHHLKKITVLDESYNASPVAV
KAALSNLGNYQAKGVRLIAVLGDMAELGVNSANFHKELVQDIIKNKIDKVFTVGAYMNHL
HEELPKELKEAHTDTSEQMAEIIKKYVNESDVILVKGRRTMKMENIVEALVK
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgaatagttctttagctgataaagctcatgaaaaatttcagggagaggaaaaaataatt
tggaataaagcttcgctggagcaagctttaggctgtgaagtaagagcttctttttcagct
tgcggggtttctataaattcaagaaccattcggaggggggaaatatttattgcaattaag
ggtgaaaattttgacggtaatgattttgcatttgacgcattagaaaaaggagcatcgctt
gcaatcgtaagcggcgctgataataatttgctgcatgacaataaaaaagtggttgtagtt
aaagataccatggttgctttaactaaaatggctaaatttgctcgtagcagaattaaaggc
aaagtgatcggagttactggaagcgtcggcaaaaccagtgcgaaagaaatgttaaaatta
gctcttgagaaccaaggtaacgtatttgcgaccgaaggctcgtataataatcatataggc
ttaccactttcgctagctaagctacccgaggatagtgattatgcgattatagaaatgggt
atgaatcatgccggtgaattagcagacttaactgtgcttgcaattccggatattgccgtc
atcaccaatgttgaagccgtacatttagagttttttaaatcagtatcagccatagctgac
gctaaatcggaaatatttaacagtatgcaagcaggcgggtttgcaattataaattttgat
aacccttatcaccaaatattagttagtaaggcgcataataaacagcttaatgtagttggg
tttagcgaaacacaaaagaccccggcacgtttgataagctataagttggaaaaaggtatt
tcgcatataaaggctgagctgttcggcagagaatacgaatatactataaatgcacctgga
aagcacttagcttataatagtatcgcagtattagccgcaactaagattgcgggagccgaa
gtggattgtgcagcatataatctttcaaagtttcatagtgtaaaaggaagaggagaaatc
catcatttaaaaaaaattaccgtgcttgatgaatcttataatgcaagcccggtggcagtt
aaagccgcacttagcaatttaggtaattatcaagctaagggtgtaaggcttattgccgtt
cttggtgatatggctgaacttggtgtaaattcggcaaatttccacaaagaattagttcag
gacattattaaaaataaaatcgataaggtatttacggttggtgcatacatgaatcatttg
catgaagaattaccgaaagagctgaaagaagctcatactgatacttcagaacaaatggct
gaaattatcaaaaaatatgtcaatgaaagcgatgttatcttagtaaaaggccgccgcaca
atgaaaatggaaaatatagttgaagctctagtaaagtag
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