Endosymbiont of Acanthamoeba sp. UWC8: I862_06645
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Entry
I862_06645 CDS
T03255
Name
(GenBank) pyruvate dehydrogenase subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
eaa
Endosymbiont of Acanthamoeba sp. UWC8
Pathway
eaa00010
Glycolysis / Gluconeogenesis
eaa00020
Citrate cycle (TCA cycle)
eaa00620
Pyruvate metabolism
eaa00785
Lipoic acid metabolism
eaa01100
Metabolic pathways
eaa01110
Biosynthesis of secondary metabolites
eaa01120
Microbial metabolism in diverse environments
eaa01200
Carbon metabolism
eaa01210
2-Oxocarboxylic acid metabolism
Module
eaa_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eaa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
I862_06645
00020 Citrate cycle (TCA cycle)
I862_06645
00620 Pyruvate metabolism
I862_06645
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
I862_06645
Enzymes [BR:
eaa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
I862_06645
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AIF81883
UniProt:
A0A075MKY8
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All DBs
Position
1370312..1371304
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AA seq
330 aa
AA seq
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MAAKKEMKTNSKLSDKQLKEAYYDMLLIRRFEEKAGQLYGMGLIGGFCHLYIGQEAIAVG
VQSVLKEGDGVITSYRDHGIMLATKSDPKYVMAELLGRATGCSKGKGGSMHMFDLPKGFY
GGHGIVGAQIPIGTGMAFAYKYKKLDNVAVVYYGDGAANQGQVYEAFNMAKLWDLPVLYV
IENNEYGMGTSVARSSSIVDLYKRGESFGISGKRVDGMNFFSVRESVLEAVEHIRSGKGP
VLLEMKTYRYRGHSMSDPGKYRSKEEVTDYRENRDPLILLGKYLEDNKIYKQEDFDSVEK
RVKDVVVEAVEFAQQSPEPSEDELFKDIYA
NT seq
993 nt
NT seq
+upstream
nt +downstream
nt
atggcagctaaaaaagaaatgaaaacaaatagtaaattatccgataaacaactaaaggaa
gcatattatgatatgcttttaatcagaaggttcgaagaaaaggccgggcagctttacgga
atggggttgataggaggattttgccacctgtatatcgggcaagaggcaatagcagtcggt
gtgcaaagtgtgcttaaagaaggtgatggagtaataaccagttaccgtgaccatggaatt
atgcttgcaacaaagagtgacccgaaatatgtgatggctgaactgcttggaagggcgaca
ggttgttcaaaaggtaaaggcggttcaatgcatatgtttgatcttccaaaaggattttat
gggggacatggtatagttggagcacagattccgattggtactggaatggcttttgcatac
aaatataaaaaattagataatgttgccgttgtttactatggcgacggggcagcaaaccaa
ggtcaggtctatgaagctttcaatatggctaagctatgggatttaccggtgctgtacgtt
atagaaaataatgaatacggaatgggtacttcggttgccagatcatcgagcatagttgat
ttatataaacgcggagaatcattcggcatttcgggtaaaagagttgacggaatgaacttt
tttagcgtcagagaatcggtactggaagcagtagaacatataagaagcgggaaaggccca
gtattacttgagatgaaaacctaccgttaccgcgggcattcgatgtctgatcccggcaaa
tacagatccaaagaagaggttacggattatagagaaaatcgtgacccgcttatactgtta
ggtaaataccttgaagataataagatttataaacaagaagactttgattccgtagagaaa
agagttaaggatgttgttgttgaagcagtcgagtttgctcaacaaagcccggagccatcg
gaagatgaattatttaaagatatttacgcttaa
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