Escherichia coli ABU 83972: ECABU_c22710 Help Entry ECABU_c22710      CDS       T01995                                  Name (GenBank) putative peptide synthetase   KO K26578   colibactin biosynthesis nonribosomal peptide synthase Organism eab  Escherichia coli ABU 83972 Pathway eab01054   Nonribosomal peptide structures Brite KEGG Orthology (KO) [BR:eab00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01054 Nonribosomal peptide structures     ECABU_c22710  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:eab01008]     ECABU_c22710 Polyketide biosynthesis proteins [BR:eab01008]  Polyketide synthase (PKS)   PKS-NRPS hybrid    Bacterial type (modular)     Colibactin synthetase      ECABU_c22710 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AMP-binding Condensation PP-binding AMP-binding_C Motif Other DBs NCBI-ProteinID:  ADN46791 LinkDB All DBs Position complement(2258299..2264799) Genome browser AA seq 2166 aa AA seqDB search MTIHHAALARMLPAEKKEKLLRQLAQSGVSPSRIPIIKADPAQAIPLSFNQERLWFLQKY DSTATNYNLYVVYRLHGVVDMPMLTEALRHVQARHAILRTRIIVRNDRPCQVIDDASSLV LDTVTLAAQAPTSALDAVIQQVINTRFDLARGPLWGVTQIIQPDQGCHLVFCAHHIIIDG ISLRLLFDELQQQYARLHAGNETSLPPPPLQYADYAFWQREWFQDTLLANELAYWRARLQ DAPLLSTFPSLHPRPAQPSTHGSRFSITLDETLSLALKHVARTQETTPFVLMLTAFQLVL MRYAQQQRLVIGMPVSGRIRPELQSSIGYYASTAVIYTDFNGVEVGREALQRVKASVKET QGRQQLPFENLVNMLDLPRSLSHSPLFQILYIYHNHVTPRAFTLAGAYWEQVTYHNQTVK YDMTVEVFQNDATFDVSFEYDLGLYDADVVKQIAEALRQHCLSLTSSLETPIGAIPLHAP ETATPRRDPLNATNVPWLGPQDVLRIIEQRCVQHPKQLAIQQHDGTLTYAELWARVQFIA MRFRAHGIQPGDRIGVLLPRHRDVIATMLATWFVGACYVPFDIHQPAARLQRLMQRARLV CLVVRQPGEWGEIVQLSLPELMQDMSNAIRYSTPCALLPDMQAYLLFTSGSTGEPKGVCV VHRGLLNLLLDMQRTFAVGSQDRLLSVTTPTFDISFLEYLLPLISGASLYLTEAERAADS FRMIPLIADYRPTLMQATPSFWHGLLMAGWRGDPELCVLAGGEALPTKVAEELLRCCGSL WNLYGPTETTIWSLKSQITQAENITLGAPIANTRIYILDNEGHPVPQGVDGELYIAGDGV AQGYDGQPELNAQFFLSEPGVPGGRMFRTGDLVRSDAQGQLFFVGRKDSQIKLRGYRIEL GEIERTLARHPHVDAAVVACIERAPLHKALAAFIITSEPPSLFEQLKNELRQQLPDYMVP TLWQRVADFPNTDNGKIDRKRLAENFVADSSLVSPQTQALSDTEQMLLALWMRYLPIKNV DPECDFFRLGGHSLLAVTLVAEINRTFHCALTLKDIFHYSTLRALSARIAQQSITDAAAS QDDWVIVHDPEHRHQPFPLTDVQRAYWLGRQTGATSIATHIYHEFDVEHFNVTRFTHAVN ALIARHEMLRARVLPDGTQQILAQVPAYQLEQRDLSALSPNARNDALMAIRDRLSHHVHP ADRWPLFDFSYSACTAQHGRLHFSLDLLIADALSMRTLQQELMMLYREPHVSLPLLPFSF RDYVQALLVEQASEAYARDQAYWQRALPQLYGPPTLPVQGDLAQLSAIRFVRRRHRLSAH NWGVLSALAQRTRITKTALLLTVFSQVLARWSLSPTFTLNLTLFNRPQGYPNAEAVIGDF TAVSLLNVCYDSQHSYAHNAQRIQVQLWEDLEHRRFSGIRASEALIHSGRFHAPMPVVFT SMLDIDGETTAQDPRDTTRFTLCPDANITQTPQVWLDHQVIELAGELHFNWDAVEQLFDT TLLDQMFGAYCHALQALVAMPQSWWGVNSSLALPTVSAPVTQAPAPTALLHHGLLRQAAL TPQETALISPIRELTYRQLSTAADHVARALLALGVQHGDRVAVVMEKGWQQIAAVHGILR LGAVYLPVDPVLPPQRRQLLLTVGEVRVQVTQPGLTQLEPSLPVLIIDDGMLDTPAAPLP EVAGDVTDLAYIIFTSGSTGTPKGVMIDHRAAMNTLEDINERFGLNAQDRVFGLSSLSFD LSVYDAFAPFMVGAALVLPEAGREKDPRHWQTVMAHGHVSVWNAVPALMQMLCEYHSGDR MSYPTLRLALLSGDWIPLTLPEQMRERLNETMDIISLGGATECAIWSVYYPIGEVESTWT SIPYGRGLRNQPVYVLNAQLEECPVGVEGEICIGGMGLAQGYLNDAEKTAASFVWREASG ERIYRTGDRGRYFADGQVAFLGRNDTQVKVNGYRIELGEVKSHLEQLDSVGSAAVVCHQG QLYAFITAAENLHPDDTDALLARVRAQLAVQLPYYLLPQHFFLLKVLPMTGNGKIDQAAM VQEVIQRMSQSTSQKSRALAHASPYEQQVAALWCEVLQREQIGLNDNFFEAGGGSIQIVL LHRRIEEIFKVTVPIAELFRLTTVKRIAGYLQAMQDNARAVNQTQQRDASRSRAQQRLVR RHQRQR NT seq 6501 nt NT seq  +upstreamnt  +downstreamnt atgacgatacatcatgccgcattggcgcgaatgttaccggcggaaaaaaaggaaaagcta ttacgacagttggcgcaatcaggcgtgtcgcccagccgcattcccatcatcaaagcggat ccggcgcaggcaatcccgctgtcgtttaatcaggagcggttgtggtttttgcaaaaatac gacagtaccgccactaactacaacctttatgtggtgtatcgtttgcatggcgtggtggat atgccgatgctcacggaggcattgcgccatgtgcaagcacgccacgccatcttgcgtacc cgtatcatagtacgtaacgatcggccttgccaggtgatagatgatgcgtcttcgttagtt ctcgatacggtcacgctggcagcgcaggccccaacttcagcgctagatgcggtaattcag caggtgataaacacccggttcgatctggcacgcggtcctctgtggggggtaactcagatt attcaacccgatcaaggttgtcatttggtgttttgcgcgcaccatatcatcatcgacggt atctcgttacggctattgttcgatgagttacagcagcagtatgctcgattgcatgctggt aatgaaacgtcgctgcctccgccgccgctgcaatatgccgattatgccttctggcagcgc gaatggttccaggataccttgctggcgaacgaacttgcctactggcgtgcgcgtttgcaa gacgcgcctctgctgtcgacatttccatcgctgcacccgcgcccggcacaaccctctaca catggttcccggttcagcatcaccctggatgaaacattaagcctcgcgttgaaacacgta gcccgcacgcaggaaacaacgccgttcgtgctgatgctgactgccttccaactggtgctg atgcgttacgctcagcaacagcgattggtgataggcatgccagtatcggggcgcattcgc ccggaattgcagagtagcattggttattatgccagcactgcggttatctacaccgatttt aatggggttgaggtagggcgcgaggcgctccagcgtgtgaaggccagcgtgaaagagacg caggggcgccagcaactgccgtttgaaaacttggtgaatatgctggatctccctcgcagc ctttcccattcaccgttgttccagatcctctatatctaccataaccacgtgaccccacgc gcttttaccttggctggtgcgtattgggagcaggtgacgtatcacaatcagaccgtcaaa tacgacatgacagtcgaggtgttccaaaacgacgccacgttcgacgtctcctttgagtac gatttggggttatacgatgctgatgtggtgaagcagattgccgaggcgctgcgtcagcac tgcttatcgttgacatcatcactggagaccccgataggggcgatccctctgcatgcaccg gagaccgcaacgccgcggcgtgatccgctcaacgccactaacgtcccgtggctcgggccg caggatgtgctgcgtatcattgaacagcgctgtgtgcagcacccaaagcaactggcaata cagcagcatgacggcacactgacctacgctgagctctgggcgcgtgtgcagttcatcgcg atgcgttttcgagcgcatggcatacaaccgggcgatcgtattggcgtgctgttgccacgt cacagggatgtgattgcaaccatgttggcgacgtggtttgtgggggcgtgctacgtgccg ttcgatattcatcagcctgccgcgcgtttgcaacgccttatgcaacgcgcgcgtttggtc tgtctggtggtccgtcagccgggagagtggggtgaaattgtacaactgtcgttgccggaa ttgatgcaggacatgtcgaatgcgatccggtattctacaccttgcgcgctgttgccggat atgcaggcctacctgttgtttacctccggcagtaccggtgaacctaaaggcgtgtgcgtt gttcaccgcgggttgctgaacttgttgttggatatgcagcgtacctttgcggttggctcg caagaccggctgctctcggtgacgacgccaacatttgatatctcattcttggagtatctg ttgccgctgatctccggtgcgagtctctatctgacagaggcggaacgcgccgcagacagc ttccgtatgattccgctgattgccgactatcgaccaacgctgatgcaggcgacgccctcg ttctggcacgggctgttgatggcgggttggcgtggcgacccggaactatgtgtgctggca ggcggtgaagcgctgccaacgaaagtggcggaagaactgttgcgctgttgtggttcattg tggaacctctacggtcccaccgaaacaaccatttggtcgctgaaatcgcagataacccaa gcggaaaacatcaccctcggcgctcccattgccaatacccgtatatacattctggacaat gagggccatccagtgccgcaaggcgttgacggcgagctttacatcgccggggatggtgtg gcgcaagggtatgatgggcagcctgagttgaacgcacagttcttcttgtcagaaccaggg gtccccggtggcaggatgttccgcactggcgatctggtcaggagtgatgcgcaggggcag ttgttttttgttgggcgcaaagatagccagatcaaactgcgcggttatcgtattgagtta ggcgaaattgaacggacgttggcacggcatccgcatgtggacgccgcggtggtggcctgt attgaaagagcaccgttacacaaagcactggcagcattcatcatcaccagtgagcctccc tcgctattcgagcaactgaaaaacgagcttcggcagcaactgccagactatatggtgcca acgctgtggcagagggtggccgacttcccgaacactgacaacggtaaaatcgatcgtaag cggttagcggaaaatttcgttgccgatagctcccttgtgtcgccgcagacgcaagcgctg agcgacacggaacagatgttgctggcgctgtggatgcgctatttgccgataaaaaacgtc gatcctgagtgcgatttctttcgcttggggggacattcgctgttggcggtaacgttggta gcagagatcaaccgcacttttcactgcgccttgaccctgaaggacattttccactactcc acactacgggcactgagtgcgcgtattgcacagcaatctatcacggacgctgccgcgtct caggatgactgggtgatagtgcacgaccctgagcatcgtcatcaaccgttcccattgacg gatgttcagcgcgcctactggcttggacgacagacgggtgctacctcgatcgcgacccac atctaccatgaatttgacgtagaacactttaatgttacgcgttttacccatgcggtgaat gcgctgatcgctcgccatgaaatgctacgtgcgcgggtactccccgacggtactcagcag attctggcgcaagtgccggcgtatcagttagagcagcgcgatctgagtgctttgtcccct aacgcacgaaacgatgccttgatggcgatccgcgatcggctgtcgcatcatgtgcatccc gcagatcgttggccgctgtttgatttcagttattcggcttgcacggcgcaacatggccgc ttgcatttcagtctcgatctgctgattgccgatgctctgagtatgcgcacgctacagcag gagttgatgatgctgtaccgtgagccccatgtgtcactgccgttgctaccgttctctttt cgtgactacgtgcaggcgctgttggtagagcaggcgagtgaagcctatgcacgcgatcag gcctattggcaacgggcgctgccgcagctgtatggcccaccaacgctgcccgtacagggc gatttggcgcaactgtctgcgatcaggttcgtacgtcgccgtcatcggctgtcagcccac aactggggagtgctgagcgcgctggcccaacgcacacgtatcaccaagacggcattgttg ttgacagtctttagccaagtgctggcacgttggagccttagcccgacgtttacgctcaat ctgacgttgttcaaccgcccgcagggttaccccaacgcagaggcagttattggtgatttt accgctgtcagcttgctgaatgtttgttacgacagccagcactcttatgcccacaacgct cagcgtattcaggtgcaactgtgggaagatctcgaacatcgtcgtttcagtgggatccgc gccagcgaggcgctgatccatagcggtcgtttccatgcgccgatgccggtggtattcact agtatgttggatatcgacggggagacgactgcgcaagaccctcgggacacaacccgtttt actctgtgtccggacgccaatattacccaaacaccgcaggtgtggctcgatcaccaggtg atcgagttggctggggagttgcatttcaactgggacgcggtcgagcaactgtttgatacc acgctgctggatcagatgtttggtgcttattgtcatgcgctgcaggcgctggttgccatg ccgcaaagttggtggggggtaaatagttctctggcgctgcccaccgttagtgcaccggtc acgcaggctcctgcacctacggccttgttgcaccatggattactgcgtcaggcagcactg acgccacaggaaactgcgctgatcagtcctatccgtgaattgacctatcgccaactgtcg acggcggcggatcatgtggcccgcgccctgttagcgctgggcgtgcagcatggcgaccgc gtggcggtggtgatggaaaaaggctggcagcagattgccgccgtacacggcattttacga ctgggtgcggtctatctgccagtggatccggtgctaccgccacagcgtcgccagcttttg ctgacggtgggcgaggtgcgggtacaagtaacgcagccgggtctcacgcaattggagccg tcgctgcccgtgctgatcatcgacgacggaatgctggacacgcctgctgcgccgttgcct gaagtggctggggatgtcacggatctggcctatatcattttcacttccggctccaccggt accccgaaaggagtgatgatcgaccaccgtgcggccatgaacacgctggaagacatcaac gaacgctttggcctcaatgcgcaggatagggtgttcgggctgtcatcattgagctttgac ctgtcggtttacgatgcctttgcgccttttatggtgggtgcagcgctggtactgccggaa gcaggacgggaaaaagatccgcgtcattggcagacagttatggcacacggtcatgtaagc gtctggaatgcagtgcccgcactgatgcagatgctgtgcgaataccacagcggcgatcgg atgagttatccgacgttgcgtctggcactgttgagcggcgactggatcccgctaacgtta ccggagcagatgcgcgagcggctcaatgaaacgatggacatcatcagtctgggtggagcg accgagtgcgccatctggtcggtctactacccgataggtgaggtggaatcgacgtggacc agtattccctacggtcggggcctgcgcaaccagccagtatacgtgctaaatgcgcaactg gaggaatgtccggtcggggtggaaggagagatttgcattggcgggatggggctggcacaa ggctacctgaacgacgcagagaaaacggcggcgagctttgtctggcgcgaagcgagtggt gagcgaatttaccgcactggggatcgcgggcgctactttgctgacgggcaagtcgccttt ttggggcgcaacgatacccaagtgaaggtgaatggttaccgtatcgaactgggggaagtc aaaagccaccttgaacagctcgacagcgtagggagtgccgccgtggtgtgccaccaggga cagctgtatgcctttatcactgccgcagaaaacctgcatcctgacgatactgacgccctg ttagcgcgtgttcgtgctcagttagccgtgcagttgccgtattacctgctgccccaacat ttctttcttctcaaggtgctgccgatgacaggcaacggcaaaattgatcaggcggcaatg gttcaagaggttatccaacgtatgtcgcaatctacatcacagaagtcgagggccctcgcg cacgcctcgccctatgaacagcaggtggccgctctctggtgcgaggtactacaacgagaa cagatcggactgaatgacaacttttttgaagcggggggcggctcaatccagatcgtgctg ttgcatcgccgtattgaggagatttttaaggttacggtacctattgctgagctatttcgc ttaaccaccgtgaaaagaattgccggttatttgcaggctatgcaggacaatgcacgggcg gtgaatcaaacacagcagcgtgatgcttcccgatcccgcgcccagcaacgacttgtacgt cgtcaccagcgtcagcgttaa

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