Ensifer adhaerens OV14: OV14_2136
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Entry
OV14_2136 CDS
T03054
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ead
Ensifer adhaerens OV14
Pathway
ead00290
Valine, leucine and isoleucine biosynthesis
ead00620
Pyruvate metabolism
ead01100
Metabolic pathways
ead01110
Biosynthesis of secondary metabolites
ead01210
2-Oxocarboxylic acid metabolism
ead01230
Biosynthesis of amino acids
Module
ead_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ead00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
OV14_2136
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
OV14_2136
Enzymes [BR:
ead01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
OV14_2136
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
PEP_mutase
Motif
Other DBs
NCBI-ProteinID:
AHK43864
UniProt:
A0AA86E1B0
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All DBs
Position
1:2072509..2074125
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AA seq
538 aa
AA seq
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MTRERIYLFDTTLRDGQQTPGIDFSVEDKIAITTLLDDFGMDYVEGGYPGANPTDTEFFK
RKRTKKASFVAFGMTKRAGVSASNDPGLAALLEANTDAICLVAKSWDYHVAVALGCSNEE
NLDNIRASVAAVVGAGREAMVDCEHFFDGYKANRAYALACAQTAFEAGARWIVLCDTNGG
TQPHEVREIVSAVIAAGVPGASLGIHAHNDTGQAIANSLAAVEAGVRQIQGTLNGIGERC
GNANLVTLIPTLALKEIYSSRFETAIDSDRLQELTKLSHAFDELLNRSPDMQAPYVGASA
FATKAGIHASALLKDPRTYEHIAPESVGNLRKVMVSDQGGKANFINALKRRGIVVGKDDP
KLDKLIAIVKEREATGYAYEGADASFALLASRILGTVPDFFHVESFRVMVERRFDANGHL
KTVSEAVVRVVVDGETMMSVAEGHGPVNALDLALRKDLGKYQSEIEDLELADYKVRILNG
GTEAITRVLIESTDGTGARWWTVGVSDNIIDASFQALMDSIIFKLLKNRDHVGLIAAE
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgaccagggaacgcatctacctcttcgacacgacgctacgggacgggcagcagacgccc
ggcatcgacttttccgtcgaggacaagatcgcgattaccaccctgctcgacgatttcggc
atggactatgtcgaaggcggctatcccggggcaaacccgaccgatacggagttcttcaag
cgcaagcgcacgaagaaggcctccttcgtcgccttcggcatgaccaagcgcgctggcgtt
tccgcctcgaacgacccgggccttgccgccctgctcgaagcaaacaccgacgcgatctgt
ctcgtggccaagagctgggattaccacgtggcggtggcgctcggctgttccaacgaggaa
aacctcgacaacatccgggcttccgtcgcagccgttgtcggcgccggccgcgaggccatg
gtcgactgcgagcatttcttcgacggctacaaggcgaaccgcgcctatgcgcttgcctgt
gcgcagactgccttcgaagcgggcgcacgctggatcgtgctttgtgataccaatggcggc
acccagccgcacgaggtgcgcgagatcgtttcggctgttatcgccgccggtgtgcccggc
gccagtctcggcatccacgcccataacgacacggggcaggcgatagccaattcgcttgca
gccgtcgaggccggcgtccgccagatacagggaacgctgaacggcatcggcgagcggtgc
ggcaacgccaatctggtgacgcttatccccaccctcgcgctgaaagagatctattccagc
aggttcgaaacggcgatcgattccgaccgcctgcaggaactgacgaagctctcgcatgct
ttcgacgaactattgaaccgctcgccggacatgcaggcgccctatgtcggtgcctcggcc
tttgccaccaaggccggcattcacgcctcggcgcttctgaaggatccacgcacctacgag
cacatcgcccctgaaagtgtcggcaatctgcgcaaggtcatggtgtccgaccagggcggc
aaggcgaacttcatcaacgcgctgaagcggcgggggatcgtggttggcaaagacgatccc
aagctcgacaagctgatcgcgatcgtcaaggagcgcgaggcgaccggttatgcctatgag
ggcgccgatgcgagtttcgcgctgctggccagccgcatcctcgggacggtgccggatttc
ttccacgtcgaaagcttccgggtgatggtcgaacgtcggttcgacgccaacggtcatctg
aaaaccgtgtcggaagcggtcgtcagggtcgtcgtcgatggcgaaaccatgatgtcggtg
gccgaaggccacgggccggtcaatgcgctcgatctggccctgcgcaaggacctcggcaaa
taccagtcggagatcgaagacctggagcttgcggactacaaggtccgtatcctcaacggc
gggaccgaggcgatcacgcgcgttctgatcgaatcgaccgatggcacgggcgcgcgctgg
tggacggtcggcgtctccgacaacatcatagatgcctcgttccaggcgttgatggacagt
atcattttcaagctgttgaagaatcgcgaccatgtcggactgatcgccgccgagtaa
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