Klebsiella aerogenes KCTC 2190: EAE_00860
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Entry
EAE_00860 CDS
T01529
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
eae
Klebsiella aerogenes KCTC 2190
Pathway
eae00230
Purine metabolism
eae01100
Metabolic pathways
eae01110
Biosynthesis of secondary metabolites
Module
eae_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eae00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
EAE_00860
Enzymes [BR:
eae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
EAE_00860
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
MAT1-1-2
Motif
Other DBs
NCBI-ProteinID:
AEG95110
UniProt:
A0A0H3FL23
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Position
complement(183551..187435)
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AA seq
1294 aa
AA seq
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MDILRGSPALSAFRINKLLARFQAANLPVSTLYAEYVHFADLSAPLSDEERERLVRLLKY
GPSLSSHTPTGKLLLVTPRPGTISPWSSKATDIAHNCGLSQVVRLERGVAYYVEAQGLSD
AQWDAVAAELHDRMMESVFTELEEGEKLFAHHQPTPVASVDLLGQGRQALIDANLRLGLA
LADDEIDYLQDAFVKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGQQQPKSLFKMI
KNTFEKNPEYVLSAYKDNAAVMEGSEVGRYFADYQTGRYDFHQEPAHILMKVETHNHPTA
ISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVT
ALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVTSHNGEELRGYHKPIMLAGGIGNIR
GEHVQKGEITVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRC
QEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFQLRDILSDEPGMSPLE
IWCNESQERYVLAVAPEQLPLFEELCRRERAPYAVIGEATAEQHLSLSDSHFNDRPIDLP
LDVLLGKTPKMTRDVQTLKAQGSELDRQPMTIADAVNRVLHLPTVAEKTFLVTIGDRTVT
GMVARDQMVGPWQIPVANCAVTTASLDSYYGEAMAMGERAPVALLDFAASARLAVGEALT
NIAATQIGELNRVKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSM
KTRWQEGSEQREMTSPLSLVISAFARVEDVRGTVTPQLSTEDNALLLIDLGKGRNALGAT
ALAQVYRQLGDQPADVRDVAQLKGFWDAMQALVAQRKLLAYHDRSDGGLLVTLAEMAFAG
HCGVTADIAALGDDRLAALFNEELGAVIQVRAADREAVEALLAMNGLADCVHYLGQATAG
DRFVITADGQPLFSESRTTLRMWWAETTWQMQRLRDNPECADQEHQAKSNDSDPGLNVKL
SFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTG
LGDFHTLVACGGFSYGDVLGAGEGWAKSILFNERVRDEFATFFHRPQTLALGVCNGCQMM
SNLRELIPGSDLWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMAGSMMPIAVSHGEGQV
EVRDSAHLAALESKGLVALRFVDNFGKVTQTYPANPNGSVNGITAVTSESGRATIMMPHP
ERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3885 nt
NT seq
+upstream
nt +downstream
nt
atggatattttgcgtggttcacctgcactgtcggcattccgtatcaacaaactgctggca
cgttttcaggcggccaacctgccggttagcaccttatacgcggagtatgttcactttgcc
gacctgagcgccccgctaagcgatgaggagcgcgaaagactggtcagactgcttaaatat
ggcccaagcctcagcagccatacgccaaccggtaaattactgctcgtcacccctcgcccc
ggcactatctccccctggtcctccaaagctaccgacatcgcccataactgcggtttatcg
caggtcgtgcggctggaacgcggcgtggcgtactacgttgaagcacagggtctgagcgat
gcgcagtgggacgccgttgcggcggagctgcacgatcgcatgatggagagcgttttcact
gagctggaagagggagagaagctgtttgctcatcatcagccgacaccggtggccagcgtg
gacctgttgggccagggacgtcaggcgctgattgacgccaacctccgtctggggctggcg
ctggccgatgacgaaatcgactacctgcaggacgcattcgttaagcttggccgcaatccg
aacgacattgaactgtatatgttcgcgcaggccaactcggaacattgccgccacaaaatt
tttaacgccgactggattatcgacggccaacaacagccgaagtcgctgtttaaaatgatt
aagaataccttcgagaaaaacccggaatatgtgctgtctgcctataaagacaacgccgcg
gtaatggaaggttccgaagtcggacgctatttcgccgactaccagaccgggcgctatgac
ttccatcaggagccggcgcacattctgatgaaagttgaaactcacaaccacccgacggcg
atttcgccgtggccgggcgccgcaaccggctccggcggcgagatccgcgacgaaggcgcc
acggggcgcggcgcgaagccgaaagcgggtctggtcggcttctcggtgtctaacctgcgt
atcccgggttttgaacagccgtgggaagaggatttcggtaaacctgagcgtatcgtgacc
gcgctggatatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaatttggt
cgtccggcgctgaatggctacttccgtacctatgaagagaaagtgaccagccacaatggc
gaagagctgcgcggctatcacaaaccgatcatgctggcgggcggtattggcaacatccgc
ggcgagcacgtccagaagggcgaaatcaccgttggcgccaagcttatcgtgctgggcggc
ccggcgatgaacattggtctcggcggcggcgcggcgtcatccatggcttccggccagtct
gatgccgatctggatttcgcctctgtacagcgcgacaacccggaaatggagcgacgctgt
caggaagtgatcgaccgctgctggcagctgggcgatgcgaacccgattctgtttatccac
gacgttggcgcgggcggtctctctaacgccatgccggagctggtgagcgatggcggccgc
ggcggaaaattccagctgcgcgatatcctcagcgatgagccgggcatgagcccgctggag
atctggtgtaacgaatcccaggagcgttacgttctggcggtcgcgccggaacagctgccg
ctgtttgaagagctgtgccgccgcgagcgcgcgccttatgcggtgatcggcgaagccacg
gcggagcaacaccttagcctgagcgacagccactttaacgatcggccgatcgacctgccg
ctggacgtcctgctcggcaaaacgccgaaaatgacgcgtgacgtgcaaacgctgaaagcg
cagggcagcgagctggatcgtcaaccaatgacgattgccgatgcggttaaccgcgtgctg
catctgccgacggtggctgagaaaaccttccttgtgaccatcggcgatcgcaccgtgacc
ggtatggtggcgcgtgaccagatggtggggccgtggcagatcccggtcgccaactgcgcg
gtgaccaccgccagcctcgatagctactacggcgaagcgatggcgatgggtgaacgcgca
ccggttgcgctgctcgactttgccgcctctgcccgcctggcggtcggcgaagcgttgaca
aacatcgccgctacgcagattggcgaactcaaccgcgtcaaactgtcggcaaactggatg
gcggcagccggtcacccgggtgaagacgccggcctgtatgaggcggtaaaagcagtcggt
gaagaactgtgtccagcgctgggcctgactatcccggtgggtaaagactcaatgtcgatg
aaaacccgctggcaggaaggaagcgagcagcgcgaaatgacctcgccgctgtcgctggtg
atctccgcgtttgcccgcgttgaagacgtgcgcggcaccgtgactccgcaactctctacg
gaagataacgccctgctgctgatcgatctcggcaaaggtcgtaacgcgctgggcgccacc
gcgctggcgcaggtctatcgccagctaggcgaccagccggccgacgtgcgtgatgtcgcg
cagctgaaaggcttctgggacgcgatgcaggcactggtggcgcagcgtaaactgctggcc
taccacgaccgctccgatggcggactgttagtgacgctggcggaaatggcgttcgccggt
cactgcggcgtaactgccgatatcgccgcgctgggcgacgatcgtctggcggcgctgttc
aacgaagaattgggcgcggtgattcaggttcgcgccgcggatcgcgaagcggtggaagcg
ctgctggcgatgaatggtctggcagattgcgtgcactacttaggccaggcgacggcaggc
gatcgttttgttatcaccgccgacggtcagccgctgttcagcgaaagccgcaccacgctg
cgtatgtggtgggcggagaccacctggcagatgcagcgcctgcgcgataacccggaatgc
gccgatcaggagcaccaggcgaagtctaacgatagcgacccgggtcttaacgttaagctg
tcgtttgatatcaatgaagatgttgccgcgccgtatattgcgaccggcgcgcgcccgaaa
gtggccgtgctgcgcgagcagggggttaactctcacgttgaaatggcggccgctttccat
cgcgccggcttcgatgccatcgatgtgcatatgagcgatctgctggcgggtcgtaccggt
cttggcgacttccatacgctggtggcctgcggcggtttctcctacggtgacgtactgggg
gcaggcgaaggttgggcgaaatcgattctgttcaacgaacgcgtacgcgatgagttcgcc
actttcttccatcgcccgcagacgctggcgctgggcgtgtgtaacggttgtcagatgatg
tccaacctgcgtgagctgatccctggaagcgacctgtggccgcgcttcgtacgcaaccac
tctgaccgctttgaagcgcgtttcagcctggttgaagtcacccagagcccatcgctgctg
ctgcagggcatggccggttcgatgatgccgattgccgtttctcacggcgaagggcaggtg
gaggtgcgggacagcgcgcacctggccgcgcttgaaagcaaaggcctggtggcgctacgt
ttcgtcgataacttcggcaaagtgacgcaaacctatccggcgaacccgaacggctcggtg
aacggcattaccgcggtgaccagcgaaagcggtcgcgcgacgatcatgatgccgcacccg
gaacgcgtcttccgtaccgtcagtaactcctggcacccggaaaactggggtgaagacagc
ccatggatgcgtatcttccgcaacgcgcgtaagcaactgggttaa
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