Klebsiella aerogenes KCTC 2190: EAE_01465
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Entry
EAE_01465 CDS
T01529
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
eae
Klebsiella aerogenes KCTC 2190
Pathway
eae00290
Valine, leucine and isoleucine biosynthesis
eae00620
Pyruvate metabolism
eae01100
Metabolic pathways
eae01110
Biosynthesis of secondary metabolites
eae01210
2-Oxocarboxylic acid metabolism
eae01230
Biosynthesis of amino acids
Module
eae_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EAE_01465
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EAE_01465
Enzymes [BR:
eae01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EAE_01465
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AEG95229
UniProt:
A0A0H3FK96
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Position
304473..306131
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AA seq
552 aa
AA seq
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MLTNPCEKYSPYPPIALPDRRWPERQITTAPRWLSTDLRDGNQALAEPMDAARKLQFWDL
LLECGFKEIEVAFPSASQTDFNFVRQLIEEQRIPEDVTIQVLTQAREELIARTFEALRGA
RQATIHLYNATAPLFRELVFGMEKAEVIELATRATRLIRQHCEQQPDTRWQYEYSPETFC
FTEPEFALEICEAVAEIWQPCGERPMIINLPATVEVNTPNVYADRIEYFCRHFSRRQDVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGVDPQLR
FTQMNRVVEIVENCNQLPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARKPGDRWQMPYL
PIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRALQQDFSQYVQQETDSHGKE
MTHNALWQLFRSRYGLLAQPTLALLDYQSDGQQDGELTLQAALRMNGETRRLNGRGNGLL
SAAANGLSALLKRHFVIKDYHEHTLGARSDSRSVAYIRCVFANGESRWGVGIDNDVARAS
LQALCNAVHARD
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atgctgaccaatccttgcgaaaaatacagcccttatccgcctatcgccctgcccgatcgc
cgctggcccgagcggcaaatcactaccgcgccgcgctggctttccaccgatttgcgcgac
ggcaaccaggcgctggccgaaccaatggacgccgcgcgtaagctgcagttctgggatctg
ttgctggagtgcggttttaaagaaatagaggtcgccttcccctccgcctcgcaaaccgat
ttcaactttgtgcgccagctgattgaggagcagcgcatccctgaagatgtcaccattcag
gtgctgactcaggcgcgggaagaactcatagcacgaacctttgaagcgctgcgcggcgcc
cggcaggcgaccatccatctctacaatgccaccgcgccgctgtttcgcgagctggttttc
ggcatggaaaaggccgaagtgatcgagctcgccacccgcgccacccggcttattcgtcag
cattgcgagcagcagccggacacccgttggcaatatgaatattcaccggaaaccttctgt
tttaccgagccggaattcgcccttgaaatctgcgaagcggtggcggaaatctggcagccc
tgcggcgaacggccaatgattattaatctcccggcaacggtcgaagtcaacacgccgaac
gtctacgccgatcggattgaatatttttgccgccacttctcgcgccgccaggatgtatgt
atcagcgtgcatccgcataacgatcgcggtaccggcgtcgccagcgccgaactggcggtg
atggccggcgccgatcgcgttgaaggctgtctgttcggcaatggcgagcgtaccggcaac
gtctgtctggtcacgctggcgatgaatctctatagccagggcgtggatccgcagttgcgc
tttacgcagatgaatcgggtggtagagatcgtcgagaactgcaaccagctcccggtacat
ccgcgtcatccatgggcaggcagtctggcctacaccgccttttcgggttcacatcaggat
gccattaaaaaagggtttgatgcccgtaaaccgggagatcgctggcaaatgccgtattta
cctatcgatccacaggatatcggctgcagctatgaagcggtgatccgcgttaacagccag
tcaggtaaaagcggcagcgcatggctgattgagcagaaccacggtcttaagctgccgcgg
gcgttgcagcaggacttcagccagtacgttcagcaagaaacggatagccatggtaaagaa
atgacccataacgcattatggcagctgtttcgcagccgttacggcctgctggcgcagccg
acgctggcgttactcgactatcagagcgacggccagcaggatggcgaactgacgttacag
gctgcgctgcggatgaatggcgaaacccgccgcttgaacggacgtggtaacggtttgtta
tccgccgccgctaacggcctgagcgcgctgttaaaacgtcatttcgttatcaaggactac
cacgagcataccctcggggcgcgcagcgacagccgctccgttgcctatattcgctgcgtc
tttgccaatggcgaaagtcgatggggcgtcggcattgataatgacgttgcccgcgcgtcg
ttacaggcgttgtgtaatgccgttcacgccagggattaa
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