Klebsiella aerogenes KCTC 2190: EAE_11240
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Entry
EAE_11240 CDS
T01529
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eae
Klebsiella aerogenes KCTC 2190
Pathway
eae00300
Lysine biosynthesis
eae00550
Peptidoglycan biosynthesis
eae01100
Metabolic pathways
eae01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eae00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EAE_11240 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EAE_11240 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EAE_11240 (murF)
Enzymes [BR:
eae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EAE_11240 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
YAcAr
Motif
Other DBs
NCBI-ProteinID:
AEG97162
UniProt:
A0A0H3FNU1
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Position
2407220..2408578
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AA seq
452 aa
AA seq
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MIRFTLSQLAEITRGELQGSDIAIDDVTSDTRKVTAGCLFVALKGERFDAHDFAEQAKAA
GAGALLVSRPLACDLPQVVVKDTRLAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLNKDHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLPQNGIAILNADNNDWLNWQSVIGDRKVWRFS
PNAANSDFTATNVHITSHGTEFTLQTPFGNIDVLLPLPGRHNIANALAATSLAMAVGADM
AAVKTGLAQLQAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGFRAMVVGD
MAELGAESAACHREVGEAAKAAGLDCVLSVGSLSADISSASGVGEHFNDKAAVVARLREL
LAEHKIMTILVKGSRSAAMEEVVRALQEIATC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgctttacattaagccagctcgccgagatcacccgcggcgaactgcagggtagc
gatatcgctatcgatgacgtgacgtccgatacccgcaaagtcacggcaggttgcctgttt
gtggcgctgaagggcgagcgattcgacgcgcatgattttgccgaacaagcgaaagcggcg
ggcgcaggcgcgctgctggttagccgcccgctggcctgcgatttaccgcaggtggtggtg
aaagatacccgtctggctttcggcgagttagcggcctgggtgcgtcagcaggtgccgacc
cgcgtcgttgcgctcaccggttcgtccggtaagacctcggtgaaagagatgaccgcggcg
atcctcagtcagtgcggcaacacgctgtataccgccggtaatctgaacaacgatatcggg
gttccgatgacgttgctgcgtctgaataaagatcaccagtatgcggtgattgaactcggc
gccaaccatcagggcgaaatcgcctggaccgtcagcctgacgcgtccggaagcagcgctg
gtcaacaacctcgccgccgcgcacctcgaagggttcggctcgctggcgggcgtggctaag
gcgaagggcgaaatctttaccggtctgccgcaaaacggcatcgcgattttgaatgccgac
aacaatgactggctgaactggcagagcgtgattggcgatcgcaaagtgtggcgcttctcg
ccgaacgcggcgaacagcgacttcacggcgaccaacgtgcatatcaccagtcatggtacc
gaatttacgctgcagaccccgttcggcaacatcgacgtactgctgccgctgccggggcgc
cataacatcgctaacgcgctggcggcaacatcgctggcgatggcggtcggcgccgatatg
gccgcggtgaaaaccgggctggcgcagctgcaagcggtgccgggacgtctgttcccgatt
caactggcggaaaaccagctgttgctggatgactcctacaacgccaacgtcggttcgatg
accgccgcggtacaggtgctggcggaaatgccgggcttccgggcgatggtggtcggcgat
atggcggagctcggcgcggaaagcgcggcctgtcatcgcgaagtgggcgaagcggcgaaa
gcggcggggctggattgcgtcctcagcgtcggttccctgagcgcggatatcagcagcgcc
agcggcgtgggcgaacattttaacgataaagccgccgtggtagctcgcctgcgcgagctg
ctggcagagcataaaatcatgaccattttagtgaagggttcacgtagtgccgctatggaa
gaggtagtacgcgcattacaggagattgcgacatgttag
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