Equus asinus (ass): 106825844
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Entry
106825844 CDS
T04645
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
eai
Equus asinus (ass)
Pathway
eai01521
EGFR tyrosine kinase inhibitor resistance
eai01522
Endocrine resistance
eai04010
MAPK signaling pathway
eai04012
ErbB signaling pathway
eai04014
Ras signaling pathway
eai04062
Chemokine signaling pathway
eai04068
FoxO signaling pathway
eai04072
Phospholipase D signaling pathway
eai04150
mTOR signaling pathway
eai04151
PI3K-Akt signaling pathway
eai04510
Focal adhesion
eai04540
Gap junction
eai04630
JAK-STAT signaling pathway
eai04650
Natural killer cell mediated cytotoxicity
eai04660
T cell receptor signaling pathway
eai04662
B cell receptor signaling pathway
eai04664
Fc epsilon RI signaling pathway
eai04714
Thermogenesis
eai04722
Neurotrophin signaling pathway
eai04810
Regulation of actin cytoskeleton
eai04910
Insulin signaling pathway
eai04912
GnRH signaling pathway
eai04915
Estrogen signaling pathway
eai04917
Prolactin signaling pathway
eai04926
Relaxin signaling pathway
eai04935
Growth hormone synthesis, secretion and action
eai05034
Alcoholism
eai05160
Hepatitis C
eai05161
Hepatitis B
eai05163
Human cytomegalovirus infection
eai05165
Human papillomavirus infection
eai05200
Pathways in cancer
eai05205
Proteoglycans in cancer
eai05206
MicroRNAs in cancer
eai05207
Chemical carcinogenesis - receptor activation
eai05208
Chemical carcinogenesis - reactive oxygen species
eai05210
Colorectal cancer
eai05211
Renal cell carcinoma
eai05213
Endometrial cancer
eai05214
Glioma
eai05215
Prostate cancer
eai05220
Chronic myeloid leukemia
eai05221
Acute myeloid leukemia
eai05223
Non-small cell lung cancer
eai05224
Breast cancer
eai05225
Hepatocellular carcinoma
eai05226
Gastric cancer
eai05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106825844 (SOS1)
04012 ErbB signaling pathway
106825844 (SOS1)
04014 Ras signaling pathway
106825844 (SOS1)
04630 JAK-STAT signaling pathway
106825844 (SOS1)
04068 FoxO signaling pathway
106825844 (SOS1)
04072 Phospholipase D signaling pathway
106825844 (SOS1)
04151 PI3K-Akt signaling pathway
106825844 (SOS1)
04150 mTOR signaling pathway
106825844 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
106825844 (SOS1)
04540 Gap junction
106825844 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
106825844 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
106825844 (SOS1)
04660 T cell receptor signaling pathway
106825844 (SOS1)
04662 B cell receptor signaling pathway
106825844 (SOS1)
04664 Fc epsilon RI signaling pathway
106825844 (SOS1)
04062 Chemokine signaling pathway
106825844 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
106825844 (SOS1)
04912 GnRH signaling pathway
106825844 (SOS1)
04915 Estrogen signaling pathway
106825844 (SOS1)
04917 Prolactin signaling pathway
106825844 (SOS1)
04926 Relaxin signaling pathway
106825844 (SOS1)
04935 Growth hormone synthesis, secretion and action
106825844 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
106825844 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
106825844 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106825844 (SOS1)
05206 MicroRNAs in cancer
106825844 (SOS1)
05205 Proteoglycans in cancer
106825844 (SOS1)
05207 Chemical carcinogenesis - receptor activation
106825844 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
106825844 (SOS1)
05231 Choline metabolism in cancer
106825844 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
106825844 (SOS1)
05225 Hepatocellular carcinoma
106825844 (SOS1)
05226 Gastric cancer
106825844 (SOS1)
05214 Glioma
106825844 (SOS1)
05221 Acute myeloid leukemia
106825844 (SOS1)
05220 Chronic myeloid leukemia
106825844 (SOS1)
05211 Renal cell carcinoma
106825844 (SOS1)
05215 Prostate cancer
106825844 (SOS1)
05213 Endometrial cancer
106825844 (SOS1)
05224 Breast cancer
106825844 (SOS1)
05223 Non-small cell lung cancer
106825844 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
106825844 (SOS1)
05160 Hepatitis C
106825844 (SOS1)
05163 Human cytomegalovirus infection
106825844 (SOS1)
05165 Human papillomavirus infection
106825844 (SOS1)
09165 Substance dependence
05034 Alcoholism
106825844 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106825844 (SOS1)
01522 Endocrine resistance
106825844 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
106825844
NCBI-ProteinID:
XP_044628214
UniProt:
A0A8C4L8M2
LinkDB
All DBs
Position
6:complement(33693898..33840605)
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVNRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISE
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaggaattaattttgcagttattaaatatgctatgc
caagctcagcctcgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccgattgataagtgggcaatagctgatgcccagtcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagagtatatttctgcagac
attttaaagctggtagggaattatgtacggaacatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacacgaacttagtgtaaagttactg
ggccacatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggctttcatgatcatttccttagtcagctatcaaagcctggagca
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggatgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcgaatcatgggcaaccaagactt
cctggtgctagcaacgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaggagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagccc
gactctgaagagaatattatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccacatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaaggtttagaaaagag
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagaacaccac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaacttactttacttgaatcagatctgtatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcacaccactaatctcactttgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgaatcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggcgtccttgaggttgttagtgctatgaactca
tcacctgtttacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctgaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaggtagcagaaattacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcggatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaat
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagagagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttccagtaccacagat
gtttgcagcgtatttgattctgatcattcgagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaaaggcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgctattcaatatcagag
cggacctctatatcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttctccctttacaccacctcct
cctcaaacaccttctcctcacggcacgagaaggcacctgccgtcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcag
catatccctaaactccctcccaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
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integrated database retrieval system