Equus asinus (ass): 106826503
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Entry
106826503 CDS
T04645
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
eai
Equus asinus (ass)
Pathway
eai01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
106826503 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
eai03032
]
106826503 (TOP2A)
03036 Chromosome and associated proteins [BR:
eai03036
]
106826503 (TOP2A)
Enzymes [BR:
eai01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
106826503 (TOP2A)
DNA replication proteins [BR:
eai03032
]
Eukaryotic type
DNA Topoisomerases
106826503 (TOP2A)
Chromosome and associated proteins [BR:
eai03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
106826503 (TOP2A)
Centrosome formation proteins
Centriole proteins
106826503 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
106826503
NCBI-ProteinID:
XP_014689356
UniProt:
A0A8C4L213
LinkDB
All DBs
Position
13:complement(42546041..42570426)
Genome browser
AA seq
1530 aa
AA seq
DB search
MDVSPLQPINENMQINKTKKNEDAKKRLSVERVYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKNFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHIGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDSEKETEKSGSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKTQRAEVLPSPSGKRVIPRVTIEMKAEAEKKFKKKIKSENTEGSPQEDGTEVEGLKQ
RLEKKQKRQPDTKTKKQITLPFKPVKGKKRNPWSDSESDMSSNESNFDDPPRETEPRRAA
TKTKFTMDLDSDEPFSDFDEKTQEEDFVPSDSSLPKTKTSLKHANKELKTQKSAVSVTDL
DADDARDSVPLSPSSSAADFPAETEIINPVSKKKVTVKKIAAKSQSSTSTTGTKKPAPKR
VKKDPGLNSDVSQKPDMPKTKNPRKRKPSTSDDSDSNFEKMISKAVTNKKSKENDDFHLD
LDSTVAPRAKSGRARKPIKYLEESDEDDLF
NT seq
4593 nt
NT seq
+upstream
nt +downstream
nt
atggacgtgtcaccgctgcagcccataaatgaaaatatgcaaatcaacaaaacaaagaaa
aatgaagatgcgaagaaaagactctccgttgaaagagtctatcaaaagaaaacgcaattg
gaacatattttgctccgcccagacacctacattggttccgtggaattagtgacccagcaa
atgtgggtttacgatgaagacgttggcattaactatagggaagtcacttttgttcctggt
ttatacaaaatctttgatgagattctagttaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagcatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatatttagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatggggaga
gctggtgagatggaactcaagccctttaacggagaagattatacgtgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagataaagatattgttgcactaatggtt
agacgagcatatgatattgctggatccactaaagatgtcaaagtctttcttaatggaaac
aagctgccagtaaaaggattccgtagctatgtggacatgtatttgaaggataaggtagat
gaaactggcaatccattgaaaattatacatgaacaagtaaaccacaggtgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttca
aagggtggcaggcatgttgattacgtagctgatcagattgtcactaagcttgtcgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagccaagaactttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtatcgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtacagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactcaactgagtgtacacttattctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttggaagagacaaa
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgccgaaattaacaatatcatcaagattgtgggtcttcaatacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaat
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagcctccctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggtaccagcaca
tcaaaagaagctaaagaatattttgcagatatgaaaagacatcgtatccaattcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaaggcaacgaaagttacttggcctt
cctgaggattacttatatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcgctaatgatgaccattatcaatttggctcaaaattttgtgggtagcaataat
ttgaacctcttgcagcctattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgctatttccacca
aaagatgatcacacattaaagtttttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctggtaaatggcgcggaaggaatcggtactggatgg
tcctgcaaaatccctaactttgatgttcgtgaaattgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccgagttataagaacttcaagggaactattgaa
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagagcttcccatcagaacgtggacccagacttataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccccctctcataacagattatagggaatac
catacagataccactgtaaagtttgttgtgaagatgactgaagaaaaactggcagaagca
gaaagagttggactacacaaagtcttcaaactccagactagtctcacatgcaactctatg
gtgctctttgaccacataggctgtttaaagaagtacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattgattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacagtgaaaaggaaactgaaaagagtggttctgtaacagat
tctggaccaaccttcaactaccttctggatatgcctctttggtatctaactaaggaaaag
aaagatgaattgtgcaaactaagaaatgaaaaagagcaagagctggaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagaattggaggct
gtcgaggccaaagaaaaacaagatgaacaagtaggacttcctgggaaaggggggaaagca
aaggggaaaaaaacacaaagggctgaagttctgccttctccaagtggaaaaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcagaaaagaaatttaaaaagaaaattaag
agtgaaaatactgaaggaagccctcaagaggacggtacagaggtagaaggcctaaaacaa
agattagagaagaaacagaaaagacaaccagataccaagacaaagaaacaaattacattg
ccatttaaaccagtcaaaggaaagaagagaaacccttggtctgattcagaatcagatatg
agcagtaatgaaagtaattttgatgaccctccacgagaaacagagccacggagagcagca
acaaaaaccaaattcacaatggatttggattcagatgaacctttctcagattttgatgaa
aaaactcaagaggaagattttgtcccatcagattctagtctacctaaaactaaaacttcc
ctaaaacatgctaacaaagaactgaagacacagaaaagtgcagtgtcagtaacagacctt
gatgctgatgatgccagggacagtgtaccactttctccaagctcttcagctgctgatttc
ccagctgaaactgaaattataaatcctgtttctaaaaagaaggtgacggtgaaaaaaata
gcagcaaaaagtcagtcttctacctccactaccggcaccaaaaagcctgcaccaaaaaga
gtcaagaaagatccaggtttgaattctgatgtctctcaaaagcctgatatgcccaaaacc
aaaaatccccgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaa
atgatttctaaagcagtcacaaacaagaaatccaaggagaatgatgacttccatctggac
ttagactcaactgtggctcctcgtgcaaaatccggacgggcaaggaaacctataaagtac
ctcgaggaatcagatgaagatgatctgttttaa
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integrated database retrieval system
