KEGG   Equus asinus (ass): 106828149
Entry
106828149         CDS       T04645                                 
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
  KO
K03934  NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:7.1.1.2]
Organism
eai  Equus asinus (ass)
Pathway
eai00190  Oxidative phosphorylation
eai01100  Metabolic pathways
eai04714  Thermogenesis
eai04723  Retrograde endocannabinoid signaling
eai04932  Non-alcoholic fatty liver disease
eai05010  Alzheimer disease
eai05012  Parkinson disease
eai05014  Amyotrophic lateral sclerosis
eai05016  Huntington disease
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05415  Diabetic cardiomyopathy
Module
eai_M00143  NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    106828149 (NDUFS1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    106828149 (NDUFS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    106828149 (NDUFS1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    106828149 (NDUFS1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106828149 (NDUFS1)
   05012 Parkinson disease
    106828149 (NDUFS1)
   05014 Amyotrophic lateral sclerosis
    106828149 (NDUFS1)
   05016 Huntington disease
    106828149 (NDUFS1)
   05020 Prion disease
    106828149 (NDUFS1)
   05022 Pathways of neurodegeneration - multiple diseases
    106828149 (NDUFS1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    106828149 (NDUFS1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    106828149 (NDUFS1)
Enzymes [BR:eai01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     106828149 (NDUFS1)
SSDB
Motif
Pfam: Molybdopterin Fer4_Nqo3 Fer4_NDSU1 Fer2_4 NADH-G_4Fe-4S_3 NADH_dhqG_C Fer2
Other DBs
NCBI-GeneID: 106828149
NCBI-ProteinID: XP_014691883
LinkDB
Position
4:11398803..11427171
AA seq 726 aa
MLRIPVRRALGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACERVGMQIP
RFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLL
ANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTR
CIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTAR
PWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQR
LTEPMVRNEKGLLTYTSWEDALSRVAGKLQSFQGKDVAAIAGGLVDAEALVALKDLLNRV
DSDTLCTEEVFPTAGAGTDLRSNYLLNSTIAGVEEADVVLLVGTNPRFEAPLFNARIRKS
WLHNDLKVALIGSPVDLTYSYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSAL
QRNDGAAVLAAVSNIAQKMRMSSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNP
PKVLFLLGADGGCVTRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEG
RAQQTKVAVTPPGLAREDWRIIRALSEIAGITLPYDTLDQVRNRLEEVSPNLVRYDDIEG
ANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAV
EEPSVC
NT seq 2181 nt   +upstreamnt  +downstreamnt
atgttaaggatccctgtaagaagggccttaggcctttctaagtctcctaaaggatgtgtt
cgaacaactgccacagcagcaagcaacctgattgaagtatttgttgatggccagtctgtc
atggtggaaccgggaactaccgtgctccaagcttgtgagagggttggcatgcagatccct
cgattctgttatcatgaaaggttgtctgttgccggaaactgcaggatgtgccttgttgaa
attgagaaagctcctaaggttgtagctgcttgtgccatgccagtaatgaaaggttggaat
atcttgacaaactcagagaaatctaagaaagccagagagggtgtgatggagttcctatta
gcaaatcacccactggactgtcctatttgtgaccaaggaggtgaatgtgatctgcaggac
cagtccatgatgtttggaagtgataggagccgatttttagagggcaagcgtgctgtggag
gacaagaacatcgggccattggtaaagactatcatgactagatgtatacagtgtactcgc
tgcatcaggtttgcaagtgagattgccggagtagatgatttgggaacaacaggcagagga
aatgacatgcaagttggcacatacatcgaaaagatgttcatgtccgagctgtctgggaat
atcattgacatctgccctgtgggtgccctgacgtctaagccctatgccttcactgcccgg
ccctgggaaacaagaaagacagaatccattgatgtaatggatgcagttggaagtaatatt
gtggtaagcacaagaactggagaagtcatgaggattttgccaaggatgcatgaggacatc
aatgaagagtggatctctgataaaaccagatttgcctatgatgggctaaaacgtcaaaga
cttactgagccaatggtcagaaatgaaaaggggcttttaacttatacctcctgggaggat
gcactctctcgtgtagctggaaagttgcagagttttcaaggcaaggatgtggcagcaatt
gcaggtggtttggtggatgctgaagctctggtagctctcaaagatttgcttaatagagtg
gactctgacacgctgtgcacggaagaggtcttccccaccgcaggtgctggcacagatttg
cgttccaattatcttcttaatagtacaattgctggtgtggaagaggcggatgttgtcctt
ctggttggtacaaatccacgttttgaggcaccactatttaatgctagaattcgcaagagc
tggcttcataatgatttgaaagtggcccttattggcagcccagtggatctcacttacagt
tatgaccatctgggagattcccccaaaattcttcaggacattgcttcgggtagccatcca
ttcagccaggtcctaaaggaagcgaaaaaaccaatggtggttttaggcagttctgcactc
caaagaaatgatggggcagcagttcttgcagcggtttccaacattgctcaaaagatgagg
atgagcagtggggtgactggtgattggaaagttatgaatatccttcataggattgcaagt
caagtagctgctttagaccttggctataaacctggggtagaagcaattcggaagaaccct
cccaaagtgctgttcctcctgggagcagatggaggctgtgtcacccgacaggatttgcca
aaggactgtttcattatttatcaaggacatcacggtgatgttggagctcctatagctgat
gttattctcccaggcgctgcctacacagagaagtctgctacttatgtcaatactgagggc
cgagctcagcagactaaagttgctgtgacacctcccggcttggcaagagaagactggaga
atcatcagagccctgtctgagattgcaggtataactctcccatacgatactctggatcaa
gtaaggaacagattggaagaagtctctcctaatcttgttcgatatgatgatatcgaagga
gctaattatttccagcaagcaaatgagctctccaagttagtgaaccagcaacttcttgct
gatccgcttgttccacctcagctaacgataaaagacttctacatgacagattcaattagc
agagcctcacagacaatggccaagtgtgtcaaagctgttacagagggtgcccaggcagta
gaggagccgtccgtatgctga

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