| Entry |
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| Symbol |
ABCC1
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| Name |
(RefSeq) multidrug resistance-associated protein 1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
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| Pathway |
| eai04977 | Vitamin digestion and absorption |
| eai04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:eai00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
106828820 (ABCC1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
106828820 (ABCC1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
106828820 (ABCC1)
04981 Folate transport and metabolism
106828820 (ABCC1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
106828820 (ABCC1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
106828820 (ABCC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:eai02000]
106828820 (ABCC1)
Enzymes [BR:eai01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
106828820 (ABCC1)
Transporters [BR:eai02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
106828820 (ABCC1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
14:19459745..19585752
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| AA seq |
1535 aa
MALRGFCSADGSDPLWEWNVTWNTSNPDFTKCFQNTVLVWVPCAYLWVCFPFYFLHLSRH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSWGRFVAPVLLVSPTLLGVTMLLA
TFLIQLERRKGVQSSGIMLTFWLIALLCALAILRSKIMAALKEDADVDVFRDVTFCLYSS
LVLIELVLSCFSDRSPLFSETINDPNPCPESSASFLSRITFWWITGMMVRGYRQPLESAD
LWSLNKEDTSEQVVPVLVKNWKKECAKARKQPVKVVYSSKDPARPKGSSKVDVNEEAEAL
IVKSPAKERDPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDQQAPD
WQGYFYTALLFISACLQTLVLHQYFHICFVSGMRVKTAVIGAVYRKALVITNSARKSSTV
GEIVNLMSVDAQRFMDLATYLNMVWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPVN
AVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLK
KSAYLGAVGTFTWVCTPFLVALSTFAVYVTIDENNILDAQKAFVSLALFNILRFPLNILP
MVISSIVQASVSLKRLRIFLSHEELEPDSIERRPGKDGGGANSITVKNATFTWARGEPPT
LSGITFSVPEGSLVAVVGQVGCGKSSLLSALLAEMEKVEGHVAIKGSVAYVPQQAWIQND
SLQENILFGRQLQERYYKAVVEACALLPDLEILPSGDLTEIGEKARESRRLADPDRAQRP
ALLREPQASQAWLQAVGLARGRPTGLLAGASAEGAVPMGAARLMTRLLVTHGISYLPQVD
VIIVMSGGKISEMGSYQELLARDGDFAEFLRTYASAEQEQDEQDNGSAGIGSPGKEGKQM
ENGMLVTDAVGKQMQRQLSNSSTYSSDIGRHCNSTAELQKDEAKKEEAWKLVEADKAQTG
QVKLSVYWGYMRAIGLFLSFLSILLFISNHVASLASNYWLSLWTDDPVVNGTQEHTTVRL
SVYGGLGILQGLSVFGYSMAVSLGGVLASRRLHVDLLHHVLRSPMSFFERTPSGNLVNRF
SKELDTVDSMIPQVIKMFMGSLCNVIGACIVILLATPIAAIVIPPLGLIYFFVQRFYVAS
SRQLKRLESVSRSPVYSHFNQTLLGVSVIRAFEEQDRFIHQSDLKVDDNQKAYYPSIVAN
RWLAVRLECVGNCIVLFASLFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMET
NVVAVERLKEYSEIEKEAPWRIQEMTPPSDWPQVGRVEFRNYGLRYREDLDLVLKRINVT
INGGEKVGIVGRTGAGKSSLTLGLFRINEPAEGEIIIDDINIAKIGLHDLRFKITIIPQD
PVLFSGSLRMNLDPFSKYSDEEVWTALELAHLKDFVSSLPDKLNHECAEGGENLSVGQRQ
LLCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRTQFDDCTVLTIAHRLNTIMDYMR
VIVLDKGEILECGSPSDLLQQKGLFYTMAKDAGLV |
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| NT seq |
4608 nt +upstreamnt +downstreamnt
atggcgctccggggcttctgcagcgccgatggctccgatcccctctgggagtggaacgtc
acctggaacaccagcaaccccgacttcaccaagtgctttcagaacaccgtgctcgtgtgg
gtgccttgcgcttacctctgggtctgcttccccttctacttcctccacctctcccgccat
gaccggggctacattcagatgacgcacctcaacaaagccaaaactgccttgggattcttg
ctgtggatcgtctgctgggcagacctcttctactctttctgggaaagaagttggggcagg
ttcgtggcccccgtgttactggtcagcccaaccctcctgggcgtcaccatgctgcttgct
acctttttaattcagctcgagaggaggaagggagtccagtcctcagggatcatgctcaca
ttctggcttatagccctactgtgtgcccttgccatcttgagatccaaaatcatggctgcc
ttaaaagaggatgctgacgtggacgtgtttcgcgatgtcactttctgcctttactcctcc
ctcgtgctgattgagctcgtgctgtcctgcttctcagaccgctcgcccctgttctctgag
accatcaacgaccccaacccgtgccccgagtccagcgcctcgttcctctccaggatcacc
ttctggtggatcacagggatgatggtccggggttaccgccagcccctggagagcgctgac
ctctggtccctgaataaggaggacacgtcagaacaggttgtgcccgttttggtcaagaac
tggaagaaggaatgtgccaaggccaggaagcagccggtgaaggtcgtctattcctccaag
gatccggcccggccgaaagggagctccaaggtggatgtgaacgaggaggccgaagctttg
atcgtcaagtcccccgcgaaggagcgggacccgtcgctgtttaaggtgctgtacaagacc
ttcgggccctacttcctcatgagcttcttattcaaggccctccacgacctgatgatgttc
gccggcccggagatcttgaagctgctcatcaacttcgtgaacgaccagcaggcccccgac
tggcagggctacttctatacggccctgctgttcatcagcgcctgcctgcagacgctcgtg
ctacaccagtacttccacatctgcttcgtgagcggcatgcgggtcaagactgccgtcatc
ggggctgtctaccgcaaggccctggtgatcaccaattcagccagaaagtcctccaccgtc
ggggagatcgtcaacctcatgtctgtggatgcccagaggttcatggacctggccacgtac
cttaacatggtctggtcagcccctctgcaagtcatcctcgctctctacctcctgtggctg
aacctggggccctcggtcctggccggggtggctgtgatgatcctcatggttcccgtcaat
gctgtgatggccatgaagaccaagacgtaccaggtggcccacatgaagagcaaagacaat
cggatcaagctgatgaatgaaattctcaacggcatcaaagtgctgaagctttacgcctgg
gagctggccttcaaggacaaggtgctggccatcaggcaggaggagctgaaggtgctgaag
aagtctgcctacctgggagccgtggggaccttcacctgggtctgcacacctttcctggtg
gccctgtctacgttcgctgtctatgtgaccatcgatgagaacaacatcttggatgcccag
aaggccttcgtgtccttggccttgttcaacatcctccgtttccccctgaacattctcccc
atggtcatcagcagcatcgtgcaggcgagtgtctccctcaagcgtctcaggatctttctg
tcgcacgaggagctggagcccgacagcattgagcggcggcctggcaaagacgggggcggc
gcgaacagcatcactgtgaagaacgccaccttcacctgggcccggggtgagccgcccacg
ctgagcgggatcaccttctccgttccggaaggttccttggtggccgtggtgggccaggtg
ggctgcggaaagtcgtctctgctctcggcgctcttggccgagatggagaaggtggagggg
cacgtggccatcaagggctccgtggcctatgtcccgcagcaggcctggattcagaatgac
tctctccaagaaaacatccttttcggacgccagctgcaggaacggtattataaggccgtg
gtggaagcctgtgccctcctgccggatctggaaatcctgcccagcggggacctcacagag
atcggtgagaaggcgcgtgagtcacggcgactggctgacccggaccgggctcagcggccg
gctctgctccgcgagcctcaggccagccaagcttggctccaggctgtggggttggctcgg
ggccgccccacagggcttcttgctggggcctcggctgagggggcagtgcccatgggagca
gctcgtctcatgacgcggctcctggtcacgcatgggatcagctacctgccccaggtggat
gtcatcatcgtcatgagtggcggcaagatctccgagatgggctcctaccaggagctgctg
gcccgggacggggacttcgccgagttcctgcgcacgtacgccagcgccgagcaggagcag
gacgagcaggacaacgggtcagccggcatcggcagtccaggaaaggaggggaagcagatg
gagaacggcatgctggtgacggacgccgtggggaaacagatgcagagacagctcagcaac
tcctccacctacagcagcgacatcggccggcactgtaacagcaccgccgagctgcagaaa
gacgaggccaagaaggaggaagcctggaagctggtggaggcggacaaggcgcagacaggg
caggtgaagctgtctgtgtactggggctacatgagggccatcgggcttttcctctccttc
ctgagcatcctcctcttcatctccaaccacgtcgcctccctggcctccaactactggctc
agcctctggaccgacgaccccgttgtcaacgggacccaggagcacaccacggtccgcctg
agcgtctacggcggcctgggcatcctgcaaggtctctccgtgttcggctactccatggcc
gtgtccctcgggggcgtcctggcctcccgccgcctgcatgtggacctgctccatcacgtc
ctccgctcgcccatgagcttcttcgagcggacgcccagcgggaacctggtgaaccgcttc
tccaaggagctggacacggtggactcgatgatcccgcaggtcatcaagatgttcatgggc
tccctctgcaacgtcatcggcgcctgcatcgtcatcctgctggccacccccatcgcggcc
atcgtcatcccgcccttgggcctcatctatttctttgtccagaggttctatgtggcctcg
tcccggcagctgaagcgtcttgagtcagtcagccgctcccccgtgtactcccacttcaac
cagaccttgctgggcgtcagcgtcatccgcgccttcgaggagcaggaccgcttcatccac
cagagcgacctgaaggtggacgacaaccagaaggcctattaccccagcatcgtggccaac
aggtggctggccgtgcgactggagtgtgtgggcaactgcatcgtcctgttcgcctccctg
ttcgccgtgatctcccggcacagcctcagtgccggcttggtgggcctctcggtgtcctac
tcgctgcaggtcaccacgtacttgaactggctcgttcggatgtcgtcagagatggagacc
aacgttgtggccgtggagagactcaaggagtattcagaaatcgagaaggaggctccctgg
agaatccaggagatgactccgcccagcgactggccccaggtgggccgcgtggaattccgg
aactatggcctgcgttaccgagaggacctggacttggttctgaagcgtatcaatgtcacc
atcaacggaggggaaaaggtgggcatcgtggggcggacgggagccgggaagtcgtccctg
accctgggcttgtttcgcatcaacgagcctgccgagggagagatcattatcgacgacatc
aacatcgccaagatcggcctgcacgatctgcgtttcaagatcaccatcattccccaggac
cccgttttgttttcgggttccctccgcatgaacctggacccattcagcaagtactcggat
gaagaagtctggacggccctcgagctggctcacctgaaggatttcgtgtcttccctcccc
gataagctgaaccacgagtgtgcagagggcggcgagaacctgagtgtcgggcagcgccag
ctcctctgcctggcccgggccctgctgaggaagacgaagatccttgtgttggatgaggcc
acagcggccgtggacctggaaacagacaacctcattcagtcgaccatccggacgcagttc
gacgattgtaccgtcctcaccatcgcccaccggctcaataccatcatggactatatgagg
gtgatcgtcctggacaaaggagaaatcctggagtgtggctccccctctgacctcctgcag
cagaaaggtctcttctacaccatggccaaagatgccggcttggtgtga |
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