Equus asinus (ass): 106830991
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Entry
106830991 CDS
T04645
Name
(RefSeq) LOW QUALITY PROTEIN: RAF proto-oncogene serine/threonine-protein kinase-like
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
eai
Equus asinus (ass)
Pathway
eai01521
EGFR tyrosine kinase inhibitor resistance
eai01522
Endocrine resistance
eai04010
MAPK signaling pathway
eai04012
ErbB signaling pathway
eai04014
Ras signaling pathway
eai04015
Rap1 signaling pathway
eai04022
cGMP-PKG signaling pathway
eai04024
cAMP signaling pathway
eai04062
Chemokine signaling pathway
eai04068
FoxO signaling pathway
eai04071
Sphingolipid signaling pathway
eai04072
Phospholipase D signaling pathway
eai04140
Autophagy - animal
eai04150
mTOR signaling pathway
eai04151
PI3K-Akt signaling pathway
eai04210
Apoptosis
eai04218
Cellular senescence
eai04270
Vascular smooth muscle contraction
eai04360
Axon guidance
eai04370
VEGF signaling pathway
eai04371
Apelin signaling pathway
eai04510
Focal adhesion
eai04519
Cadherin signaling
eai04540
Gap junction
eai04550
Signaling pathways regulating pluripotency of stem cells
eai04613
Neutrophil extracellular trap formation
eai04625
C-type lectin receptor signaling pathway
eai04630
JAK-STAT signaling pathway
eai04650
Natural killer cell mediated cytotoxicity
eai04660
T cell receptor signaling pathway
eai04662
B cell receptor signaling pathway
eai04664
Fc epsilon RI signaling pathway
eai04666
Fc gamma R-mediated phagosome formation
eai04720
Long-term potentiation
eai04722
Neurotrophin signaling pathway
eai04726
Serotonergic synapse
eai04730
Long-term depression
eai04810
Regulation of actin cytoskeleton
eai04910
Insulin signaling pathway
eai04912
GnRH signaling pathway
eai04914
Progesterone-mediated oocyte maturation
eai04915
Estrogen signaling pathway
eai04916
Melanogenesis
eai04917
Prolactin signaling pathway
eai04919
Thyroid hormone signaling pathway
eai04921
Oxytocin signaling pathway
eai04926
Relaxin signaling pathway
eai04928
Parathyroid hormone synthesis, secretion and action
eai04929
GnRH secretion
eai04935
Growth hormone synthesis, secretion and action
eai05010
Alzheimer disease
eai05022
Pathways of neurodegeneration - multiple diseases
eai05034
Alcoholism
eai05132
Salmonella infection
eai05152
Tuberculosis
eai05160
Hepatitis C
eai05161
Hepatitis B
eai05163
Human cytomegalovirus infection
eai05164
Influenza A
eai05165
Human papillomavirus infection
eai05167
Kaposi sarcoma-associated herpesvirus infection
eai05170
Human immunodeficiency virus 1 infection
eai05200
Pathways in cancer
eai05205
Proteoglycans in cancer
eai05206
MicroRNAs in cancer
eai05207
Chemical carcinogenesis - receptor activation
eai05208
Chemical carcinogenesis - reactive oxygen species
eai05210
Colorectal cancer
eai05211
Renal cell carcinoma
eai05212
Pancreatic cancer
eai05213
Endometrial cancer
eai05214
Glioma
eai05215
Prostate cancer
eai05218
Melanoma
eai05219
Bladder cancer
eai05220
Chronic myeloid leukemia
eai05221
Acute myeloid leukemia
eai05223
Non-small cell lung cancer
eai05224
Breast cancer
eai05225
Hepatocellular carcinoma
eai05226
Gastric cancer
eai05230
Central carbon metabolism in cancer
eai05231
Choline metabolism in cancer
eai05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106830991
04012 ErbB signaling pathway
106830991
04014 Ras signaling pathway
106830991
04015 Rap1 signaling pathway
106830991
04370 VEGF signaling pathway
106830991
04371 Apelin signaling pathway
106830991
04630 JAK-STAT signaling pathway
106830991
04068 FoxO signaling pathway
106830991
04072 Phospholipase D signaling pathway
106830991
04071 Sphingolipid signaling pathway
106830991
04024 cAMP signaling pathway
106830991
04022 cGMP-PKG signaling pathway
106830991
04151 PI3K-Akt signaling pathway
106830991
04150 mTOR signaling pathway
106830991
09133 Signaling molecules and interaction
04519 Cadherin signaling
106830991
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
106830991
09143 Cell growth and death
04210 Apoptosis
106830991
04218 Cellular senescence
106830991
09144 Cellular community - eukaryotes
04510 Focal adhesion
106830991
04540 Gap junction
106830991
04550 Signaling pathways regulating pluripotency of stem cells
106830991
09142 Cell motility
04810 Regulation of actin cytoskeleton
106830991
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
106830991
04625 C-type lectin receptor signaling pathway
106830991
04650 Natural killer cell mediated cytotoxicity
106830991
04660 T cell receptor signaling pathway
106830991
04662 B cell receptor signaling pathway
106830991
04664 Fc epsilon RI signaling pathway
106830991
04666 Fc gamma R-mediated phagosome formation
106830991
04062 Chemokine signaling pathway
106830991
09152 Endocrine system
04910 Insulin signaling pathway
106830991
04929 GnRH secretion
106830991
04912 GnRH signaling pathway
106830991
04915 Estrogen signaling pathway
106830991
04914 Progesterone-mediated oocyte maturation
106830991
04917 Prolactin signaling pathway
106830991
04921 Oxytocin signaling pathway
106830991
04926 Relaxin signaling pathway
106830991
04935 Growth hormone synthesis, secretion and action
106830991
04919 Thyroid hormone signaling pathway
106830991
04928 Parathyroid hormone synthesis, secretion and action
106830991
04916 Melanogenesis
106830991
09153 Circulatory system
04270 Vascular smooth muscle contraction
106830991
09156 Nervous system
04726 Serotonergic synapse
106830991
04720 Long-term potentiation
106830991
04730 Long-term depression
106830991
04722 Neurotrophin signaling pathway
106830991
09158 Development and regeneration
04360 Axon guidance
106830991
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106830991
05206 MicroRNAs in cancer
106830991
05205 Proteoglycans in cancer
106830991
05207 Chemical carcinogenesis - receptor activation
106830991
05208 Chemical carcinogenesis - reactive oxygen species
106830991
05230 Central carbon metabolism in cancer
106830991
05231 Choline metabolism in cancer
106830991
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
106830991
09162 Cancer: specific types
05210 Colorectal cancer
106830991
05212 Pancreatic cancer
106830991
05225 Hepatocellular carcinoma
106830991
05226 Gastric cancer
106830991
05214 Glioma
106830991
05221 Acute myeloid leukemia
106830991
05220 Chronic myeloid leukemia
106830991
05218 Melanoma
106830991
05211 Renal cell carcinoma
106830991
05219 Bladder cancer
106830991
05215 Prostate cancer
106830991
05213 Endometrial cancer
106830991
05224 Breast cancer
106830991
05223 Non-small cell lung cancer
106830991
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
106830991
05161 Hepatitis B
106830991
05160 Hepatitis C
106830991
05164 Influenza A
106830991
05163 Human cytomegalovirus infection
106830991
05167 Kaposi sarcoma-associated herpesvirus infection
106830991
05165 Human papillomavirus infection
106830991
09171 Infectious disease: bacterial
05132 Salmonella infection
106830991
05152 Tuberculosis
106830991
09164 Neurodegenerative disease
05010 Alzheimer disease
106830991
05022 Pathways of neurodegeneration - multiple diseases
106830991
09165 Substance dependence
05034 Alcoholism
106830991
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106830991
01522 Endocrine resistance
106830991
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eai01001
]
106830991
Enzymes [BR:
eai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
106830991
Protein kinases [BR:
eai01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
106830991
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
ABC1
C1_2
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
106830991
NCBI-ProteinID:
XP_044610509
LinkDB
All DBs
Position
21
Genome browser
AA seq
644 aa
AA seq
DB search
MEHIQGAWKTISNGFGFKDXDPSCISPKVVQQFGYQRRASDDGRLTDSSKTSNTIRVFLP
NKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLHEHKGKKARLDWNTDAASLIGE
ELQVDFLDHVPLTTHSFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKVPTMC
VDWSNIRQLLLFPNSTFGDSGVPALPSLTMRRMRESVSRMPVSSQHRYSTPHAFTLNISS
PSSEGSLSKRQRSTSTPNVHMVSTTLPVDSRVIEDAIRSHSESASPSALSSSPNNLSPTG
WSQPETPVPAQRERAPGSGTQEKNKIRPRGQRDSNCYWEIEASEVMLSTRIGSGFFGTVY
KGKWHGDVAVKILKVVDPTPEHFQAFRNKVAVLRKTRHVNVLLFMGYMTKDNLAIVTQWC
EGSSLYKHLHVQETKFQMFQLIDITRQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKI
GDFGLATVKSRWSGSQQVEQPTGSVLWLAPEVIRMQDNNPFSFQSNVYSYGIVLYELMTG
ELPYSHINNXDQILFMVGRVYASPDLSKLYKNCPKAVKRLVADCVKKVKEERPLFPQILS
PIELLQHSLPKINRSASEPYLHRVPHTEDIDACTLTTSPRLPVF
NT seq
1935 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggggcctggaagacgatcagcaatggttttggattcaaagacnat
gaccccagctgtatctcccctaaagtagttcagcagtttggctatcagcgtcgggcgtca
gatgatggcagacttacggactcttctaagacaagtaacactatccgtgttttcttgcca
aataagcaaagaacggtggtcaatgtgcgaaatggaatgagcttgcatgactgccttatg
aaagcactcaaggtgaggggcctgcaaccggagtgctgtgcagtgttcagacttcacgaa
cacaaaggtaaaaaagcacgtttagattggaatactgatgctgcctcattgattggagaa
gaacttcaagtagatttcctggatcatgttcctctcacaacacacagctttgctcggaag
acctttctgaagcttgccttttgtgacatctgtcagaagttcttgctaaatggatttcga
tgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagtacctactatgtgt
gtggactggagtaatatcagacaactcttattgtttccaaattccacttttggtgatagt
ggagtcccagcactgccttccttgacaatgcgtcggatgcgagagtctgtttcccggatg
cctgttagttcccagcacagatactccacgccccacgccttcacactcaacatctccagt
ccctcctctgaaggttccctctccaagaggcagaggtcaacgtccacacctaatgtccac
atggtcagcaccaccctgcctgtggacagcagggtgattgaggatgcaattcgaagtcac
agtgaatcagcttcaccttcagccttgtccagcagccccaacaatctgagcccaacaggc
tggtcacagcctgaaacccctgtgccagcacagagagagcgggcaccaggatctgggacc
caggagaaaaacaaaattagacctcgtggacagagagattcaaactgttactgggaaata
gaagccagtgaagtgatgctctccactcggattgggtcaggcttctttggaactgtgtat
aagggcaaatggcatggagatgttgcagtgaaaatcttaaaggttgttgaccccacacca
gagcacttccaggcgttcaggaacaaggtggctgtcctgcgtaaaacacggcacgtgaac
gtcctgctcttcatggggtacatgacgaaggataacctggcaattgtgacccagtggtgt
gagggcagcagcctctacaaacacttgcatgtccaggagaccaagttccagatgttccag
ttgattgacatcacccggcagacagctcagggaatggactatttgcatgcaaaaaacatc
atccacagagatatgaagtccaacaatatatttctccacgaaggcctgacagtgaaaatt
ggagactttggtttggcaacagtcaagtcgcgctggagtggttctcagcaggttgaacaa
cccactggctctgtcctgtggttggccccagaggtgatccgaatgcaggataataacccg
ttcagcttccagtccaatgtctactcctatggcattgtactgtatgagctcatgacaggg
gaactgccttactcccacatcaacaactgagatcagatcctcttcatggtgggccgagtg
tatgcctccccagaccttagtaagctatacaagaactgccccaaagcagtgaagaggctt
gtggctgactgcgtgaagaaagttaaggaggagaggcctctttttccccagatcttgtct
cccattgagttgctccaacactctctaccgaaaatcaaccggagcgcttctgagccatac
ctgcatcgggtgccccacaccgaggacatcgatgcctgcacgttgaccacgtcccctaga
ctgcctgtcttctag
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