Equus asinus (ass): 106831384
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Entry
106831384 CDS
T04645
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
KO
K04440
mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:
2.7.11.24
]
Organism
eai
Equus asinus (ass)
Pathway
eai01522
Endocrine resistance
eai04010
MAPK signaling pathway
eai04012
ErbB signaling pathway
eai04014
Ras signaling pathway
eai04024
cAMP signaling pathway
eai04068
FoxO signaling pathway
eai04071
Sphingolipid signaling pathway
eai04137
Mitophagy - animal
eai04140
Autophagy - animal
eai04141
Protein processing in endoplasmic reticulum
eai04210
Apoptosis
eai04215
Apoptosis - multiple species
eai04217
Necroptosis
eai04310
Wnt signaling pathway
eai04380
Osteoclast differentiation
eai04510
Focal adhesion
eai04530
Tight junction
eai04620
Toll-like receptor signaling pathway
eai04621
NOD-like receptor signaling pathway
eai04622
RIG-I-like receptor signaling pathway
eai04625
C-type lectin receptor signaling pathway
eai04657
IL-17 signaling pathway
eai04658
Th1 and Th2 cell differentiation
eai04659
Th17 cell differentiation
eai04660
T cell receptor signaling pathway
eai04664
Fc epsilon RI signaling pathway
eai04668
TNF signaling pathway
eai04722
Neurotrophin signaling pathway
eai04723
Retrograde endocannabinoid signaling
eai04728
Dopaminergic synapse
eai04750
Inflammatory mediator regulation of TRP channels
eai04910
Insulin signaling pathway
eai04912
GnRH signaling pathway
eai04914
Progesterone-mediated oocyte maturation
eai04917
Prolactin signaling pathway
eai04920
Adipocytokine signaling pathway
eai04926
Relaxin signaling pathway
eai04930
Type II diabetes mellitus
eai04931
Insulin resistance
eai04932
Non-alcoholic fatty liver disease
eai04933
AGE-RAGE signaling pathway in diabetic complications
eai04935
Growth hormone synthesis, secretion and action
eai04936
Alcoholic liver disease
eai05010
Alzheimer disease
eai05012
Parkinson disease
eai05016
Huntington disease
eai05017
Spinocerebellar ataxia
eai05020
Prion disease
eai05022
Pathways of neurodegeneration - multiple diseases
eai05132
Salmonella infection
eai05133
Pertussis
eai05135
Yersinia infection
eai05142
Chagas disease
eai05145
Toxoplasmosis
eai05152
Tuberculosis
eai05161
Hepatitis B
eai05162
Measles
eai05166
Human T-cell leukemia virus 1 infection
eai05167
Kaposi sarcoma-associated herpesvirus infection
eai05169
Epstein-Barr virus infection
eai05170
Human immunodeficiency virus 1 infection
eai05171
Coronavirus disease - COVID-19
eai05200
Pathways in cancer
eai05208
Chemical carcinogenesis - reactive oxygen species
eai05210
Colorectal cancer
eai05212
Pancreatic cancer
eai05231
Choline metabolism in cancer
eai05415
Diabetic cardiomyopathy
eai05417
Lipid and atherosclerosis
eai05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
106831384 (MAPK8)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106831384 (MAPK8)
04012 ErbB signaling pathway
106831384 (MAPK8)
04014 Ras signaling pathway
106831384 (MAPK8)
04310 Wnt signaling pathway
106831384 (MAPK8)
04668 TNF signaling pathway
106831384 (MAPK8)
04068 FoxO signaling pathway
106831384 (MAPK8)
04071 Sphingolipid signaling pathway
106831384 (MAPK8)
04024 cAMP signaling pathway
106831384 (MAPK8)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
106831384 (MAPK8)
04137 Mitophagy - animal
106831384 (MAPK8)
09143 Cell growth and death
04210 Apoptosis
106831384 (MAPK8)
04215 Apoptosis - multiple species
106831384 (MAPK8)
04217 Necroptosis
106831384 (MAPK8)
09144 Cellular community - eukaryotes
04510 Focal adhesion
106831384 (MAPK8)
04530 Tight junction
106831384 (MAPK8)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
106831384 (MAPK8)
04621 NOD-like receptor signaling pathway
106831384 (MAPK8)
04622 RIG-I-like receptor signaling pathway
106831384 (MAPK8)
04625 C-type lectin receptor signaling pathway
106831384 (MAPK8)
04660 T cell receptor signaling pathway
106831384 (MAPK8)
04658 Th1 and Th2 cell differentiation
106831384 (MAPK8)
04659 Th17 cell differentiation
106831384 (MAPK8)
04657 IL-17 signaling pathway
106831384 (MAPK8)
04664 Fc epsilon RI signaling pathway
106831384 (MAPK8)
09152 Endocrine system
04910 Insulin signaling pathway
106831384 (MAPK8)
04920 Adipocytokine signaling pathway
106831384 (MAPK8)
04912 GnRH signaling pathway
106831384 (MAPK8)
04914 Progesterone-mediated oocyte maturation
106831384 (MAPK8)
04917 Prolactin signaling pathway
106831384 (MAPK8)
04926 Relaxin signaling pathway
106831384 (MAPK8)
04935 Growth hormone synthesis, secretion and action
106831384 (MAPK8)
09156 Nervous system
04728 Dopaminergic synapse
106831384 (MAPK8)
04723 Retrograde endocannabinoid signaling
106831384 (MAPK8)
04722 Neurotrophin signaling pathway
106831384 (MAPK8)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
106831384 (MAPK8)
09158 Development and regeneration
04380 Osteoclast differentiation
106831384 (MAPK8)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106831384 (MAPK8)
05208 Chemical carcinogenesis - reactive oxygen species
106831384 (MAPK8)
05231 Choline metabolism in cancer
106831384 (MAPK8)
09162 Cancer: specific types
05210 Colorectal cancer
106831384 (MAPK8)
05212 Pancreatic cancer
106831384 (MAPK8)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
106831384 (MAPK8)
05170 Human immunodeficiency virus 1 infection
106831384 (MAPK8)
05161 Hepatitis B
106831384 (MAPK8)
05171 Coronavirus disease - COVID-19
106831384 (MAPK8)
05162 Measles
106831384 (MAPK8)
05167 Kaposi sarcoma-associated herpesvirus infection
106831384 (MAPK8)
05169 Epstein-Barr virus infection
106831384 (MAPK8)
09171 Infectious disease: bacterial
05132 Salmonella infection
106831384 (MAPK8)
05135 Yersinia infection
106831384 (MAPK8)
05133 Pertussis
106831384 (MAPK8)
05152 Tuberculosis
106831384 (MAPK8)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
106831384 (MAPK8)
05142 Chagas disease
106831384 (MAPK8)
09164 Neurodegenerative disease
05010 Alzheimer disease
106831384 (MAPK8)
05012 Parkinson disease
106831384 (MAPK8)
05016 Huntington disease
106831384 (MAPK8)
05017 Spinocerebellar ataxia
106831384 (MAPK8)
05020 Prion disease
106831384 (MAPK8)
05022 Pathways of neurodegeneration - multiple diseases
106831384 (MAPK8)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
106831384 (MAPK8)
05418 Fluid shear stress and atherosclerosis
106831384 (MAPK8)
05415 Diabetic cardiomyopathy
106831384 (MAPK8)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
106831384 (MAPK8)
04936 Alcoholic liver disease
106831384 (MAPK8)
04932 Non-alcoholic fatty liver disease
106831384 (MAPK8)
04931 Insulin resistance
106831384 (MAPK8)
04933 AGE-RAGE signaling pathway in diabetic complications
106831384 (MAPK8)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
106831384 (MAPK8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eai01001
]
106831384 (MAPK8)
Enzymes [BR:
eai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
106831384 (MAPK8)
Protein kinases [BR:
eai01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
106831384 (MAPK8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kdo
ABC1
RIO1
Kinase-like
FTA2
APH
DUF530
Motif
Other DBs
NCBI-GeneID:
106831384
NCBI-ProteinID:
XP_044615456
LinkDB
All DBs
Position
2:complement(125390197..125489597)
Genome browser
AA seq
427 aa
AA seq
DB search
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPSPLGAAVINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLEASA
GPLGCCR
NT seq
1284 nt
NT seq
+upstream
nt +downstream
nt
atgagcagaagcaaacgtgacagcaatttttatagtgtagagattggagattctacattc
acagtcctgaaacgatatcagaatttaaagcctataggctcaggagctcaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaaactaagccggcca
tttcagaatcagactcatgctaagcgggcttacagagagctagttcttatgaaatgtgtt
aatcacaaaaatataattggccttttgaatgttttcacaccacagaagtccctagaagaa
tttcaggatgtttacatagtcatggagctcatggatgcaaatctttgccaagtgattcag
atggaactagatcatgaaagaatgtcctaccttctctatcagatgctgtgtggaatcaag
caccttcactctgctggaattattcatcgggacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccaggactgcaggaactagtttt
atgatgacaccttacgtagtgactcgctactacagagcacctgaggtcatcctaggcatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttatcgaacag
cttggaacaccatgtcctgaattcatgaagaaactacagccaacagtaaggacttatgtc
gaaaacagacctaaatatgctggatatagctttgagaaactcttccctgatgtacttttc
ccagctgactcagaacacaacaaacttaaagccagtcaggcaagggatttattatccaaa
atgctggtgattgacgcgtctaaaaggatctctgtggatgaagcgctccagcacccgtat
atcaatgtctggtatgacccttcggaagcagaagctccaccaccaaagatacctgacaag
cagttagatgaaagggaacacacgatagaagagtggaaagaattgatatacaaggaagtt
atggacttggaggagagaaccaagaatggagttatacgggggcagccctctcctttaggt
gcagcagtgatcaatggctctcagcatccatcgtcatcatcgtctgtcaatgatgtgtct
tcaatgtcgacagatccaactttggcctcggatacagacagcagtcttgaagcatctgct
ggacctctgggctgctgtagatga
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