Equus asinus (ass): 106832426 Help Entry 106832426         CDS       T04645                                  Symbol PCLO Name (RefSeq) protein piccolo   KO K16882   protein piccolo Organism eai  Equus asinus (ass) Pathway eai04911   Insulin secretion Brite KEGG Orthology (KO) [BR:eai00001]  09150 Organismal Systems   09152 Endocrine system    04911 Insulin secretion     106832426 (PCLO)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:eai04131]     106832426 (PCLO) Membrane trafficking [BR:eai04131]  Exocytosis   Calcium ion-dependent exocytosis    Others     106832426 (PCLO) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-piccolo C2 PDZ FYVE_2 Motif Other DBs NCBI-GeneID:  106832426 NCBI-ProteinID:  XP_014698675 LinkDB All DBs Position 1:74258584..74638801 Genome browser AA seq 5154 aa AA seqDB search MGNEASLEGDGLPEGLAAAGAAAGGGGAGGAGSPLHTVIPASMEADLSQLSEEERKQIAA VMSRAQGLPKGSVPPAAAEPPSMHRKQELDSSHPPKQPGKLPDPGRPAQPGLSKSRTTDT LRSEQKLPGRSPSTISLKESKSRTDFKEEHKSSMMPGFLSEVNPLSAVSSVVNKFSPFDL ITDSDASQEETTKKQKIAQKEQGKPEGIVKPPQQQSPKPIPKQQGPVRAPPQHDGSLKSV SSQQPEKIKSQPPGTEKPIQGLTQSPQTDQAKLPLQRDAARPQTKQSDTVKGESVKASVQ SPFKPTVQQASPAKPPAQQPGPEKLSTPQPGPAKPSTQQPGPTKAPAQQPGPAKPSPTQP AAKLPAQPPATTKPATQQPRPKSPAQPPGPAKSPAQQVGPGKTPAQQPDPAKPPPQQPGP AKPPPQQPGPAKPPSSARKAPPSSTPAQQSPLLTQPGPAKPPPQQPGPAKPPSSTAWPSK APPQQPGPAKAPPQQPGPAKPPPQQPGPAKPAPQQPGPAKPPLQQPGPAKPPPQQPGPPK PPPQQPGPAKAPPQQPGPAKVSDQQAIKPVSRTGAGKPLQPPTSPSAVQTPVQGLPKTIC PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEIKEWLCLNCQMQRALGGD LASIPSSPQPKPKTGPAIPKTGVSKPSPQSQQISPKKDTAPKQDISKAPESKTPPPPVKP PALHGSPLVMAKQSPMAESPSKPAPPKEPSVPSEQAKIPMADDKPKQPKTVKPAIDTVSS SSTETKPDIPTSRVQSQDQEKTTPALKTDSAKPSQSFPPTGEKVTPFDSKVIPRPASDSK IISHPGPSSEGKGQKQFDSVQKREEPKKAQTKISPKPDAKLMLKGSPTPLDPRPTTGQTA PTSQQPPKPQEQSIRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTA GQPGSHLQSGSGAPTKQGPPPSQPPPSQGPPKPTDQVPLAPAKVMPVEKETKAPVAEKLE PKAEQVPTVKRTETEKKPLPIKDSKPSTAEPQKAVLPSKPEKNPKPESACPLCKTELNLG SKDPPNFRTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIGKMPPMQ SGPKASSISVPIEPLSQKTAMPAQVKVKKKEQEVKTEAEKITPEKVKETPSIEKIPPKVT TDQKQEESKLEKDKISAPQEEKPPPEDKKPLSKEEKPTTEDKKLPPEDKRPPPEDKRPPP EDKKLSPEAKTSALEEEQKPILLRSQVQIAEEKPEGRVVPQAMQEKKPTQTKTEALPSGT PQSLPKEDDEMTHKLKERPQAAYTAKTDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSD TGYSSDGISSSLGEIPSLIPSDEKDLLKGLKKDSFSQESSPSSPSDLAKLESTVLSILEA QASTLVEEKSEKKTEPLVVSPEEPKDQQKTQSFSETPIAEEELKESQKEKDTFKKESQQD IPSRKDHEEKSEFVDDITTRRQPYDSVEDSSESENSPVPQRKRRTSVGSSSSDEYKQEDS QGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSIESQRKEETKGKGKVTPG KHRRLTRKSSASFDDDAGRRHSWHDEDDETFDESPELKYRETKSQESEELVVAGGGGLRR FKTIELNSTIADKYSAESSQKKTALYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFT PGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRSHGPLLPTIEDSSEEEELREEEELL KEQEKQRELEQQQRKTSSKKSKKDKEELRAQRRRERPKTPPSNLSPIEDASPTEELRQAA EMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEG SQKALKSAEEMYEEMMHKPHKYKAFPATNERDEIFEKEPLYGGMLIEDYIYESLVEDTYN GSVDGSLLTRQEDQNGFMQQRGREQKIRLPEQIYEDPMQKITDLQKEFYELESLHSVVPQ EDIVSSSYIIPESHEIVDLGGMVTSTSEEKKLLDADAAYEELMKRQQMQLIPGCSLTQPP IRDDMTESTMDFDRVPDASLTSSVLSGTSLTDSTSSATLSIPDVKITQHFSTGEIEDEYV TDYAREIQEIIAHESLILTYSEPSESVPPSDTPSLTSSVSSVCTTDSSSPITTLDSITTV YTEPADIVTKFENSEEISSSTYFPGSIIDYPEEISISLDQTATTDGRTSADHIVISLSDM EPSVLESVGIKPEGLIAEAISTDLSLSGKDPVKKAKKETGNGIILEVLEAYKDKRKESEG ELTKISLSEIVFDQPPSSVIAFPMKEPVSTACFISGEVFGQVKPASHLPSGSPSVSSPPT RTHAFFRSSSLDTSAQPPPSPAPPPSPPPLPSPPPPPPLPPPTSPKPTVHPKRKLTVTAP VTLTTTATPLVDAVTTVETTAFLGSNGLPVTKICTTAPPPVPPKPSSIPSGLVFTHRPEP SKPPVAPKPAVPQLPVTTQKPTDTHPKPTGLSLTSNMTLNLVTSADYKLPSPTSPLSPHS NKSSPRFSKSLMETYVVITLPSEPGTPTDSSSSQAITSWPLRSPPKDLISIESVFSVIPP VTAAERSTSSEQSLDLSGTLETFSTIPVTTLSSFQAAPTSVTQFTTTEVSKAEVSAARSL IPSVGLSSVSVSIPPEPLALDNLHLEKHQHKETGKLQLVGDAIDLRTVSKVEINVTEKCM DLSASAMDMKRQTTINEVYGRQISAVQPSIINLSATSSVVTPISLVTETVTVVTCTASES YTVGTESLVGVEHATAAPLQLTASKHAEPPCKIPSGQAFPTVREEAPINLSLGTSAHAMT LAITKPVTAPPVGVTSGWTDSTTCQGITDGEVVDLSTTKSQRTVVTVDESTSSVVTKIIE DDEKPVDLTAGRRAVCCDMVYKLPFGRSCTAQQPATTLPEDRFGYRDDHYQYDRSGPYGY RGIGGMKSSMSDTNLAEAGHFFYKSKNAFDYSGGTDAAVDLTSGRITTGEVMDYSSKTTG PYPETRQVISGVGISTPQYSTARMTPPPGSQYGVGNVLRSSNGVVYSSVATPIPSTFAIT TQPGSIFSTSVRDLSGVHTTDTVTSLSALHQSQPMPRSYFLTTGASEMDITVTGIDINAS LQTITMETLAAETVDSVPTLTTASEVFSEVVGDDSSILIVPEEDKQQQQLDLERELLELE KIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLYQQEEERQAQFMMRQE TLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQAILEGQYAAP EGSQFWATEDTTTTASAVVAIEIPQNQGWYTVQSDGVTQYIAPPGILSTVSEIPLADVVV KDEKQPKKRSSGAKVRGQYDEMGENMADDPHCFKKIMDSGVQTDDEDAADRSYVSRRRRT KKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDSTTEADKTKPLSKVSSIAVQTVAEI SVQTEPVGTIRTPSVRARMDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSAT SPPKDKKRPTPLEIGYSTHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYE KPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYT TKGSQTMTPSGTQKKVKRTLPNPPPEETSAGTQSTYSTMGTVSRRRICRTNTMARAKILQ DIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERAYL QGVAEDRDYMSDSEVSSTRPTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSP YTQYQYSSPAPPTQSPTPYTQQSHFQQQTLYHQQVSPYQTQPTFQAVATMSFTPQAQPPP TPQPSYQLPSQMMVIQQKPRQTTLYLEPKITSNYEVIRNQPLMIAPVSTDNTYAVSHLGS KYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRNYVLIDDIGEITKETAALST AFSFHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQTSSRLHSYVKAEEDPMEDPYELKLL KHQIKQEFRRGAESLDHLTGLSHYYHADTSYRHFPKSEKYSISRLTLEKQAAKQLPAAIL YQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYMTSSTSSIGGISSRARLLQDDITFG LRKNITDQQKFMGSSLGTGLGTLGSTIRSALQEEADKPYGSGSRSRPSSVYGLDLSIKRD SSSSSLRLKAQEAEALDVSFSHASPSGRTKPTSLPISQSRGRIPIVAQNSEEESPLSPVG QPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHMREESRTRGYDRDIAFIMDDFQHA MSDSEAYHLRREETDWFDKPRDSCLENGHGLDRKLPERLVHSRPLSQHQEQIIQMNGKTV HYIFPHARIKITRDSKDHTVSGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEHTGK LMEGMQVLEWNGIPLTSKTYEEVQSIISQQSGEAEICVRLDLNMLSDSENPQHLELHEAP KAVDKAKSPGVDPKQLAAELQKVSLQQSPLVLSSVVEKGSHAHSGPTSAGSSSVPSPGQP GSPSVSKKKHGSSKPTDATKVVSHPITGEIQLQINYDLGNLIIHILQARNLVPRDNNGYS DPFVKVYLLPGRGQVMVVQNASAESKRRTKYVQKSLNPEWNQTVIYKSISMEQLKKKTLE VTVWDYDRFSSNDFLGEVLIDLSSTSHLDNTPRWYPLKEQTESIDHGKSHSSPSSQQSPK PSVIKSRSHGIFPDPSKDMQVPTIEKSHSSPGSSKSSSEGHLRSHGPSRSQSKTSVTQTH LEDAGAAIAAAEAAVQQLRLQPTKPTNQRPAESSVSTGSSGSSFGSGYSVDSEGSSSAAG EANLFPIPRIGKMGQNGQEPVKQPGVGVGLADTEVKTQVMGEIKIALKKEMKTDGEQLIV EILQCRNITYKFKSPDHLPDLYVKIYVMNISTQKKMIKKKTRVCRHDREPSFNETFRFSL SPAGHSLQILLFSNGGKFMKKTLIGEASIWLDKVDLRKRIVNWHKLLVSPTQTH NT seq 15465 nt NT seq  +upstreamnt  +downstreamnt atgggcaacgaggcgagcctggaaggggacgggctcccggaagggctggcggcggcggga gccgccgctggcggaggaggggctggcggggcggggagccccttgcacaccgtgatcccg gctagcatggaggcggatctgagccagctgagcgaagaggagaggaaacagatcgctgct gtcatgtcaagggcgcaggggctgcccaagggaagcgttcccccggccgctgcggagccg ccttccatgcacaggaaacaagagttggatagtagtcatcctccaaagcaaccaggaaaa ctgccggaccctgggcgtccagctcagcctggtctcagtaaaagcagaactacagacact ctgaggtcagagcagaaattgcctggaaggagtccttccactattagcttgaaagaatca aagtccagaactgattttaaggaagagcacaaatctagtatgatgcctggcttcctctca gaggttaatcctttaagtgctgtctcctctgttgtaaataaattcagtccttttgatttg ataacagactctgatgcctcccaggaagaaactaccaagaaacaaaaaatagctcagaag gaacaaggaaaacctgaaggaattgtaaagcctccacaacaacagtcacccaagccaatt cctaagcagcaaggacctgtgagggccccacctcaacacgatggctctctcaaatcagta tcttctcagcaaccagaaaaaattaaatcacaacctccagggacagaaaagccaattcaa gggcttacccagtctcctcagacagaccaggccaaattgccacttcaaagagatgcagcg aggcctcagactaaacagtcagacacagtaaaaggagaatcagttaaagcctcagtacaa agtccattcaaaccaacagttcagcaagcaagtcctgcgaaacctccagcccagcagcct ggacctgaaaaactttccacgccacagcctgggcctgcaaagccctcaactcagcaacca gggccaacaaaggccccagctcaacagccaggtccagcaaagccctcacctacacagcct gcagcaaaactcccagcccaaccaccagcaacaacaaagcctgcaactcagcagcccagg cccaagtctccagctcagcctcctgggcctgcaaagtctccagctcagcaggttgggccc ggaaagactccagctcagcagcctgacccagcaaagccccctcctcaacagcctggccca gcaaagccccctcctcaacagcctggcccagcaaagcccccctcctcagcccgcaaagcc cccccctcctcaacacctgcccagcaaagccccctcctcacacagcctggcccagcaaag ccccctcctcaacagcctggcccagcaaagcccccctcctcaacagcctggcccagcaaa gcccctcctcaacagcctggcccagcaaaggcccctcctcaacagcctggcccagcaaag ccccctcctcaacagcctggcccagcaaagcccgctcctcaacagcctggcccagcaaag ccccctcttcaacagcctggcccagcaaagccccctcctcaacagcctggcccaccaaag ccccctcctcaacagcctggcccagcaaaggcccctcctcaacagcctggcccagcaaag gtctcagatcagcaagctataaaaccggtaagccgaacaggagctgggaaacctctgcag ccaccgacttctccatctgcagtacagactccagtacaaggcctccctaaaaccatctgt cctctttgcaacaccactgaacttctgttgcatgttccagaaaaggccaattttaacaca tgcactgagtgtcaaactactgtctgtagcctctgtggttttaatcccaatcctcattta accgagataaaagagtggctctgcttaaactgtcaaatgcaaagagctctaggaggtgat ctggcttcaattccatcatcaccccagcccaaaccgaagactggtcctgctattcctaag acaggagtgagcaaaccatccccacagtcacagcagatttctccaaagaaggatactgca cccaaacaggatatctcaaaggcacctgagtctaaaacgcccccaccaccagtgaaaccg ccagcccttcatggttctcccctagtcatggctaagcaatctcccatggcagagtcccca tccaagccagcccctcccaaagagccttctgtcccgtctgagcaggccaagatccccatg gctgatgataaaccaaagcagcccaagacggtaaagccagccatagacactgtgtcttca tcgtcaacagaaacaaaacctgacattccaacctccagagtacagtcacaggatcaagaa aaaacaacccctgctctaaaaacagactctgccaaaccctcacagagttttccaccaaca ggagagaaagtcaccccatttgattctaaagtcatacctcgtcctgcatcagattcgaaa attatttcacatcctgggcctagttcagagggcaaaggtcaaaaacagtttgattcagtt caaaagagggaagaacccaagaaagcacaaaccaaaataagtcctaagccagatgcaaag ctgatgctaaaagggtcaccaacacccctggacccacgacctaccactggccaaactgcc cccacatctcaacagcccccaaagcctcaggagcagtcgatacgtttcagtctcaatctg ggaagtattactgatgcccctaaatcacagcccacaactcctcaagaaactgtgactgga aaactctttgggttcggagcatcaatcttcagccaggcatcaaatttaatctccacagca ggtcagcctggatctcatttacaaagtgggtcaggggccccaacaaaacaaggccctcct ccttcacagccacctccttctcaggggccacccaaacccacagatcaggtaccactagca cctgcaaaggttatgcctgtggaaaaggaaacaaaagctccagtagctgaaaaattagag cccaaagctgaacaagttccaacagtaaaaagaacagaaacggaaaaaaagcctctgcct attaaggatagcaaaccttcaacggctgagcctcaaaaagctgtccttccctctaaacca gagaaaaatcccaaaccagaatcagcctgtcctctctgcaaaactgaactcaacctaggt tctaaggatcctcctaacttccgcacttgcactgaatgcaagaatcaagtgtgtaacctc tgtggatttaacccgacaccacacttgactgagattcaagaatggctttgtttaaattgc caaacccagagagcaatatcaggacagcttggagacataggcaaaatgccacctatgcag tcaggaccaaaagcctcttccatatctgtccctatagagccgctgtctcagaaaacagca atgcctgcccaagtaaaagtgaaaaagaaggaacaagaagtaaaaacagaagctgaaaaa atcactccagaaaaagtaaaagaaaccccttcaattgaaaaaattccccctaaggtaacc acagatcaaaaacaagaagagagtaaactagagaaagacaaaatttcagcccctcaagaa gaaaagccaccccctgaagacaaaaagcctctctccaaagaagaaaagccaaccactgaa gacaaaaagctacctcctgaagacaaaaggccacctcctgaagacaaaagaccacctcct gaagacaaaaagttatccccagaagcaaaaacatcagccctagaggaggaacagaaacct atcttacttagaagtcaagtacaaattgctgaagaaaaacctgaaggcagagtggttcca caggcaatgcaagaaaagaaaccaacacagaccaagacagaagctttaccgtctggcaca cctcagagtctgcctaaggaagatgatgagatgactcataaactcaaagaacggccacag gcagcatacacagcaaagactgaccaggtggaacctgggaaagaaaaaacagaaaaggaa gatgacaaatcagacacttcaagttctcagcagccgaaaagcccacaaggtctgagtgac acaggatattcttctgatggaatatcaagttcacttggtgaaattcctagtcttattcca agtgatgaaaaggatttgctcaaaggactcaaaaaggactctttctcacaagaaagcagc ccttccagcccctcagatttggctaagttagaaagtacagtcttatccattttggaagct caggcaagtactcttgttgaagaaaaatcagaaaagaaaacagagccccttgtggtttct cctgaggagcctaaggaccaacagaaaactcaaagtttttctgaaacaccaattgcagaa gaagagctcaaagagagtcaaaaagaaaaagacacttttaaaaaagagagccaacaagac attccttccagaaaggaccatgaagaaaagtctgagtttgttgatgacataactacaaga agacagccttatgattcagttgaagacagtagcgaaagtgaaaactcacctgttccacaa agaaaacggagaactagtgttggttcatcaagcagtgatgagtacaaacaggaagatagt caaggatcaggagaagaagaggactttattcgaaaacaaatcatagaaatgagtgctgat gaagatgcttctggttctgaagatgatgaattcattaggaaccagctcaaagagattagt agtagtattgagagccagaggaaggaagaaacaaaagggaaagggaaagtaaccccggga aaacacaggcgattgactcgaaaaagtagtgcaagttttgatgatgatgcagggagacgc cattcgtggcatgatgaagatgatgagacatttgatgaaagtcctgaacttaaatacaga gaaactaaaagtcaggagagtgaagaacttgtagttgctggaggaggagggctacgtcga ttcaaaacgattgaactcaacagcacaatagcagacaaatactctgcagagtcatcacag aaaaaaacagctttgtattttgatgaagagccagaattagaaatggaaagcctaacagac tctccagaagataggtcaaggggggaaggatcttctagtcttcatgcttccagcttcact cctggcacatccccgacatcagtgtcatcacttgatgaggacagtgacagtagcccaagt cacaaaaaaggagagagcaaacagcaacgcaaagctcggcacagatcacatggccctctt ttgcctactattgaagattcttcagaggaggaagaattgagggaagaagaagaattatta aaggaacaagaaaagcagcgagaattagaacagcaacaaagaaagacttctagtaagaaa tcaaagaaagacaaagaagaacttcgggctcagagaaggagggaaagaccaaagacacca cccagtaatctctctcccattgaagatgcatctccaacagaagaattacgtcaagctgca gaaatggaggagctccatcgatcttcttgttctgaatattcacctagcatagagtcagac ccagaaggctttgaaataagcccagaaaaaataatagaagtgcaaaaagtttataaattg cccacagctgtgtctttatactcaccgacagatgagcaatctattatgcagaaagaaggt agccaaaaggcgttaaaaagtgctgaggagatgtatgaagaaatgatgcataaaccccac aaatataaagcttttccagctacaaacgaacgagatgaaatttttgaaaaagagcctttg tatggtggaatgttaatcgaggattatatttatgaatctttagtagaggacacatataat ggttcggtagatggcagtctgctaacaaggcaagaagatcaaaatggatttatgcagcag agagggagagagcaaaaaataagacttccagaacagatttatgaagatccaatgcagaaa attacagacctccagaaagagttttatgagttagaaagcttacattctgttgtgcctcaa gaagacattgtttcaagctcttatatcatcccagaaagccacgagatagtggatctgggt ggtatggtcacttctaccagtgaagaaaaaaaattattggatgctgacgctgcctatgaa gaactcatgaagaggcaacagatgcaattaatacctggatgcagtctgacccagcccccc atcagagatgatatgacagagtccaccatggactttgacagggtgcctgatgcatctttg acatcaagtgttctctcaggaacatctcttacagattcaaccagcagtgcaacactctct atcccagatgttaaaataactcaacatttttcaacaggagaaattgaggatgaatatgta accgattatgcaagagaaattcaagagataattgcccatgaatcactgattctgacttac tctgagccttcagaaagtgtcccaccctctgacacaccctctcttacatcatctgtttct tcagtttgtaccacagatagctcctcacccattactaccctggatagcataaccacagtt tataccgagcctgcggacatagtaactaaatttgaaaattctgaggaaatttcttcatca acatattttccaggcagcattatagactatccagaagaaataagtatatctttagatcag actgccacaacagatggtagaactagtgctgatcatattgtgatttccttatctgatatg gaaccttctgtcctagaatctgtaggaattaaacccgaggggttaattgctgaagctatt tccactgacttatctctatctggaaaagacccagtgaagaaagccaagaaggaaactggg aatggaattattctggaagttttagaagcttacaaggataaaaggaaggagtctgagggt gaactaacaaaaattagcttatctgaaattgtgtttgatcaaccaccttcttctgtaata gcctttccaatgaaggaaccggtttcaactgcatgctttatatctggagaggtctttggt caagtaaaacctgcatctcatttgccttctggcagtccttctgtttcctctcctccaact agaactcatgcattctttcgaagttcttctttggatacatcagcacaacctcctccttct cctgctcctcctccttctccacctccccttccatctcccccacctcccccacctcttcct ccaccgacttcacctaaaccaactgttcatcctaaaagaaagttaacagttacagctcca gtgactctaactactacagcaacacctctagttgacgctgttactacagtggagaccaca gcttttctagggagtaatgggttacctgtaacaaaaatatgtaccactgcacctcctcct gttcctcctaagccatcttcaattccatccggacttgtatttacacatagacccgagcca agcaaacctccagttgcccctaaaccagcagttcctcagcttccagtaactacacaaaaa ccaacagatacgcaccccaaaccaacaggactatctttaacttcaaatatgacattaaat ttagtgacttcagcagattataaattaccttccccgacttccccactttcccctcactct aacaagtcctcaccaagattttccaaatcccttatggaaacttacgttgttatcacgttg ccatctgaacctgggactccaacagattcttcaagtagtcaggcaattaccagttggccc ctgagatcacctcccaaagatctgatttccattgaatcagtgttttctgtaattcctcct gtgacagctgcagaaaggtccacttcttcagaacagagccttgacctttcaggcactttg gagacattttccactatccctgtcaccacattatcatcatttcaagcagccccaacttca gttacacagtttaccacaaccgaagtttccaaggctgaggtttcagcagccagaagtcta atccccagtgtgggtctcagcagtgtctctgtatcaattcctccagagcctcttgctcta gataacctacatttagagaagcatcagcataaagaaactggaaagttgcaacttgttggt gatgccattgatttgcgtacagtatcaaaagtagaaattaatgtaactgaaaaatgtatg gatctttctgcttctgcaatggatatgaaaaggcagaccacaataaatgaagtttatggg agacaaattagtgctgtgcaaccctctattataaatctcagtgcaacttcgtcagtagtg actccaatatctctggtcaccgagacagtgactgttgtcacgtgcacagctagtgaaagt tacactgtgggcacagaaagcctagtgggtgtagaacatgcaacagcagcaccactccag cttactgcatcaaagcatgctgaacccccatgcaagataccaagtggccaggcctttcct acagttagggaggaagcaccaataaacttatctttaggtacttcagcacatgcaatgaca ttggctattacaaaacctgttactgcacctcctgttggtgtcacaagtggatggactgat agcaccacatgccaggggatcactgatggggaagtagtggatctcagtacaacaaagtct cagagaactgttgtaacagtggatgagtctacttcaagtgtggtgaccaaaataatagaa gatgatgaaaaacctgttgatctgactgcaggaagaagggccgtgtgctgtgatatggtt tataagttaccttttggaaggagctgcacagcacagcagcctgcaactacacttcctgag gaccgttttggttatagagatgaccactatcaatatgatcgatcagggccttatggttat agagggattgggggaatgaaatcttccatgtctgacactaatttagcagaagctggacat ttcttttataaaagtaagaatgcttttgattattctggaggaactgatgcagctgtagat ctaacttcagggagaattactacaggtgaggtaatggattattcaagcaagactacaggt ccatatccagagacacgacaagtcatttcaggagttgggattagtaccccacagtattcc acagcaagaatgactccacctccaggatcccagtatggtgtggggaatgttttgaggtca tctaatggtgttgtctattcttcagtagcaactccaattccctccacatttgctatcacc acacaacctggctccattttcagcacctctgtgagggatttgtctggtgtgcacacaact gacacagtgacttcattatccgccctgcaccagagccagccaatgcctagatcatatttc ctaacaacaggtgcatctgaaatggacattacagtaactggtattgatatcaatgccagt ttgcaaaccattactatggagactcttgctgctgagacagtagactcagttcccacttta accacagcatccgaagtgttttctgaagtggtgggagatgacagtagtattttaattgtc cctgaagaagataaacaacaacagcagctggacttggagcgtgagctcttggaactggaa aaaattaagcagcagcgttttgctgaggaattagagtgggaacgtcaggaaattcaaagg ttccgagaacaagaaaagatcatggttcaaaaaaagctggaggagctgcagtctatgaaa cagcaccttctctatcagcaagaagaagaacgtcaagcccagttcatgatgaggcaggaa acattagctcagcaacagttacagcttgagcagatccaacagctgcagcaacagcttcac cagcagctagaggagcaaaagattcgccagatctaccagtataactatgatccttctgga actgcttctccacaaaccactactgagcaagcaattttggaaggtcagtatgctgcccca gaaggcagtcagttttgggcaactgaagatacaaccaccacagcctcagctgttgtggca attgaaataccacaaaaccaaggatggtacacagttcagtctgacggtgttactcagtac attgccccacctggcatcctgagtactgtttcagaaatacctctagcagatgttgttgta aaagacgaaaaacaacccaaaaagagaagttctggagctaaagtccgtggacagtacgat gagatgggggaaaatatggcagatgatcctcactgctttaaaaagataatggacagtggt gtacaaactgatgatgaagatgcagcagatcggagttatgtgagtaggaggaggagaact aaaaagagtgtcgatacaagtgtccaaactgatgatgaagatcaggatgaatgggatatg cctactagatcaaggagaaaagctcgtgtagggaaatatggtgacagcactacagaggct gacaagaccaaacccctttccaaagtctccagtatagcagttcaaaccgtagcagagata tctgtgcaaactgaaccagttggaaccataagaacaccttcagtacgggcacgcatggat gccaaggtagaaataattaaacacatttcagcacctgaaaagacttacaaagggggaagt ttaggatgtcagacagaagcagattcagacacacagagtcctcaatatctgagtgccaca tctccacccaaagacaagaaacgcccaacacctttagagattggttattcaactcacctt cgggcagattccacagtacagctggctccttccccacccaaatctccaaaggtcctttat tcacccatctcaccactttcaccaggcaaagccttagaatctgcctttgtaccttatgaa aaacccctccctgatgatataagtccacagaaagtactgcacccagatatggctaaagtt cccccagcaagtcctaaaacagccaagatgatgcagcggtccatgtctgaccccaagcct ctgagtccaacagcagatgaaagttccagggctccttttcagtataccgagggctacacg acaaaaggttctcaaaccatgacaccctctggcacccagaaaaaagttaagagaactctt ccaaatccacctcctgaggagacctccgcaggaactcagtcgacatatagcacaatgggc acagtctccaggaggaggatctgcagaaccaacacaatggcacgagcgaagattctccag gatatagacagagagcttgatcttgtggagagggaatctgcaaagcttagaaaaaaacaa gcagaacttgatgaggaagaaaaggagattgatgccaagttacggtacctggaaatgggg attaacaggaggaaagaggcattactaaaggagagagaaaagagagagcgagcttacctc cagggagtagccgaggatcgggattacatgtctgacagtgaggtgagcagcaccagacca acccgaatagaaagccagcatggcatagagcgaccaagaactgctccccaaactgaattc agccagtttataccaccacaaacccaaacagaatctcaactagttcctcctacgagtcct tatacacaataccaatactcttcccctgcccctcctacccagtcacctaccccatacacc caacaatcccattttcagcaacaaactttgtatcatcagcaagtttcaccttaccagact cagccaacattccaagctgtggcaacaatgtccttcacacctcaagctcaacctccacca actccacaaccttcttatcagttaccatcacagatgatggtgatacaacaaaagccacgg caaactacgttgtatttggagcccaagataacttcaaactatgaggtgattcgcaaccaa ccactgatgatagctcctgtttctactgataatacgtatgctgtttcccatcttggtagt aagtacaatagcttagacttgagaataggattggaggaaagaagtagcatggcaagcagt ccaatatcaagcatatctgcagattctttctatgcagatatagaccatcatactccacga aattatgtcttaattgatgacattggagagattaccaaagaaacagcagcattaagcact gcgtttagctttcatgaaaaggatctgtcaaaaacagatcgtctccttcgaaccactgaa acacgtagatctcaagaagtgacagatttcctagcacctttgcagacttcctccagattg catagttatgtgaaagcagaggaagacccaatggaggatccttatgagttaaaacttctg aaacatcagattaaacaggaattccgtagaggagcagagagcttagatcaccttactggt ctttctcattattaccatgccgatactagctataggcattttccaaaatctgaaaagtat agcattagtagactcacacttgaaaaacaagcagcaaaacaactacccgcagccatactt tatcaaaagcagtcaaaacataagaaatcactaattgaccctaaaatgtcaaaattttca cctattcaagaaagtagagaccttgaacctgattattcgagctatatgacttctagcact tcgtctattggtggcatttcttccagagcaaggcttcttcaagatgatatcacttttggc ctcagaaaaaatattacagaccaacaaaaatttatggggtcatctcttggcactggacta ggcaccttaggaagtaccatccggtcggctctgcaggaggaagcggacaagccctacggt agtggcagcaggtctagaccttcctctgtctatgggctggatttatcaattaaaagagac tcttccagctcttccctgagactgaaagctcaagaagctgaagctctagatgtttccttt agtcatgcatccccttctggtagaactaagcctaccagtctgccaattagccagagtaga ggaagaataccaattgtggcccagaattctgaagaagaaagtccactcagtcctgttggc cagccaatgggaatggccagggctgctgctggacccctgccacccatatctgcagacacc agggatcagtttggatcaagtcactcattgcctgaagttcagcaacacatgagagaagaa tcacggactcgaggctatgaccgtgacatagcattcatcatggatgacttccaacatgcc atgtcagacagtgaagcctatcacctgcgtcgtgaagaaacagattggtttgacaaaccc agggattcttgtttggaaaatggacatggtctggatcgaaaactgccagaaagattggtc cactctagaccgctcagtcaacatcaagagcaaattatacagatgaacgggaagactgtg cactacatctttcctcatgcaaggataaaaataacgagagactctaaggatcacacagtt tcaggtaatggattaggaattagaattgtgggtggtaaagaaattcctggacatagtgga gaaattggagcctatattgccaagattcttcctgggggaagtgcagaacatacagggaaa cttatggaagggatgcaagtattggaatggaatggaattcctttaacttctaaaacatat gaagaagtgcagagtatcattagtcagcaaagtggggaagcagagatatgtgtaagactg gacctcaatatgctatcagattctgaaaatccccagcacctggaacttcatgaagcacca aaagccgtggataaagcgaaatccccaggggttgatcctaagcagttggcagcagagctc cagaaggtttcactacaacagtcaccactggttctgtcttccgtcgttgaaaaaggatct cacgctcattcaggtcctacatcagcaggatccagttccgttcccagccctgggcaacca gggtcaccttcagtgagcaaaaagaaacatggcagcagcaagcctactgatgcaacaaag gttgtctctcatccaattacaggggaaattcagcttcaaatcaactatgatcttggaaat ctcataatacatattctccaagcaagaaaccttgtccctcgagacaacaatggttattct gacccctttgttaaagtgtaccttcttccagggcgaggtcaagtcatggttgtccagaat gcaagtgctgagtctaaaagaaggactaaatatgttcagaaaagtcttaatcctgagtgg aatcaaacagtaatttataaaagtatctccatggaacagctcaagaagaaaacactggag gtgacagtctgggattatgatagattttcttccaatgactttcttggtgaggtattgatt gatttatcgagcacatctcaccttgataacactcctaggtggtatcctctcaaagaacag actgaaagtattgatcatggcaagtcccattccagtccaagcagccagcagtccccaaag ccatctgtcatcaaaagcagaagccatggcatcttccctgacccatccaaggacatgcag gttcccaccattgagaaatcccatagtagtcctggtagctcgaaatcctcctctgaaggc catctccgctctcatggaccatctcgcagtcaaagcaaaaccagtgtcacccagacccac ctggaagatgcaggagctgccatagccgctgctgaagccgccgtgcaacaactccgcctt caaccaacaaagcctaccaatcagcggcctgcagaaagctccgtgtccaccggctcctcg ggcagcagctttggcagcgggtatagcgtggacagcgaaggaagcagcagcgctgcaggg gaggctaatctatttcctattccaaggatagggaaaatggggcagaatggacaagagcct gtgaaacagccaggagtaggagtgggactggcagacactgaagttaaaactcaggtaatg ggagaaatcaagattgcattgaagaaggaaatgaagacagatggtgaacaactaatagtt gaaatactccaatgcagaaatatcacctacaaatttaaatctcctgatcacttaccagat ttatatgtgaaaatatatgtgatgaacatctctacccaaaaaaagatgattaagaaaaaa acaagagtatgtagacatgatcgagagccttcattcaacgaaacttttagattcagccta agtcctgctggacattctcttcagattttacttttctccaacggagggaaatttatgaaa aagaccttgattggtgaagcctctatctggcttgacaaagtggatctcagaaaaagaata gtcaactggcacaaacttttggtcagtcctactcaaacccattga

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