Equus asinus (ass): 106834163
Help
Entry
106834163 CDS
T04645
Symbol
DOT1L
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
eai
Equus asinus (ass)
Pathway
eai00310
Lysine degradation
eai01100
Metabolic pathways
eai05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
106834163 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
106834163 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
eai03036
]
106834163 (DOT1L)
Enzymes [BR:
eai01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
106834163 (DOT1L)
Chromosome and associated proteins [BR:
eai03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
106834163 (DOT1L)
HMT complexes
Dot1-containing complex
106834163 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
106834163
NCBI-ProteinID:
XP_044608529
LinkDB
All DBs
Position
20:1407589..1476209
Genome browser
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHLLQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDAKSNTTTPTKVP
EGKAAAPVDTPMDSGAEDEKAGATAVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKASTA
NPERKPKKTQTALDLLHAQTVSQAASPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKDNQELRSQSLQLL
KARCEELKLDWSTLSLESLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDGLPLPLRGKGALGRELEAEPGRLPLELDCSKLSLPHFSSMSPELSMNGHAAGY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPSHGSRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHAVSSKAAAGELHPRAEHAKENGLPYQSPVIANGIKLSPQDPRPSSPVALQM
TGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARST
PSPVPQPRDSSSTLEKQPGAGAHGAASSAAGGRGLALAPAGFSYAGSVAISGALAGSPAP
LAPGVEPAAFDESSSSGSLFATMGSRSSTPQQPPLLVQPRNSGSASPAHQLCASPRLGAA
QGPPPDAGKADLPCESGLSDPESEARRRVVFTISAGAPGSKQSPSSKHSPLPSGARGDSG
QSHGQDSRKRGRRKRASVGTPSLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQ
PLEITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPG
SARIERKIATISLESKSPPKTLENGGGLAGRKPTPAGEPVNSSKWKSTFSPISDLGLAKA
ADSPLQASSSLSQNSLFAFRPGLDEPGSADAKLAAHPRKSFPSALAGAGGLSPSSTPPNG
FAFSGGLAADLSAHSFSDGAALSHKAPEVAGLGAAPSFPAPRGKEAGAAEPGSFVNKRQL
DGLGGPKGEGGKGRDVGELGLPVVGPSDRALLVHSKAGKGRDREPDSKNGHNLFISAATV
PPGGLLSGPGLATVASSAGSATPSAQTHRPFLGSFTPGPQFALGPMSLQANLGSSVLQSL
FSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFAG
SGAACRSATLSLTPLQAVAATPASSFQAPASVESRPPPPPXPPGRPPAGPPTLPAPAPPN
AALPPPPALLPANSELLQSLASLPANRAFLPASSAASLPPANASLSIKLASLPHKAARPA
LTGPRQPLPGLALARAPVLPQASSTGPSAVWVSLGMPPPCAARLAGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgcccgtgggcgccgagcccgccgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcacgagatcatcgagacc
atccgatgggtgtgtgaagaaatcccagatctcaagcttgccatggagaactatgtttta
atcgactacgacaccaaaagctttgaaagcatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaaggggaccacgcagcccatgaagctgaacacg
cggccgtccaacgggctcctgcggcacctgctgcagcaggtgtacaaccactcggtgacc
gaccctgagaagctcaacaactacgagcccttctccccggaggtgtacggcgagacctcc
tttgacctggtggcgcagatgatcgacgagatcaagatgaccgaggatgacctattcgtg
gacctgggcagcggagtgggccaggtcgtactgcaggtcgctgctgccaccaactgcaaa
catcactatggcgtcgagaaagccgacatcccagccaagtacgcagagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggcgatttcctctcggaagagtggagagagcggattgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctaaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgccactgaag
ggctcggtgtcgtggacggggaagccggtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaagaggca
gcccggcgccggcagcagcgggacgccaagagcaacacgaccactcccaccaaggtgccc
gagggcaaggcggccgcgcctgtggacacccccatggattctggtgctgaggacgagaaa
gctggggcgaccgccgtcaaaaagccgtccccgtccaaagcgcggaagaagaagctgaac
aagaagggccggaagatggccggccggaagcgcgggcgtcccaagaaggcgagcactgcg
aaccccgagcgtaagcccaagaagacccaaactgcactggacctcctgcacgcgcagacc
gtgtctcaggcggcgtcgccctcgccgcaggatgcgtacaagtcacctcacagcccgttc
taccagctacctcccagcgtgcagcggcacccccccgaccagctgctgctggcccccacc
ccgcccgcactgcagaagctgctagagtccttcaagattcagtacttgcagttcttggcg
tacacgaagacccctcagtacaaggccaacctgcagcagctgctggaccaggagaaggag
aagaacgctcgcttgctgggtgccgcgcagcagctgttcggccactgccaggcccagaag
gaggagatcaagaggctcttccagcagaagctggatgagctgggagtgaaggcgctgacc
tacaatgacctgatccaagcgcagaaggagatctcggctcacaaccagcagctgagggag
cagacggagcagctggagaaggacaaccaggagctgcggagccagagcctgcagctgctc
aaggctcggtgtgaggagctgaagctggactggtccacgctgtccctggagagcctgctg
aaggagaagcaggccctgaagagccagatctccgagaagcagcggcactgcctggagctg
cagatcagcatcgtggagctggagaagagccagcggcagcaggagctcctgcagctcaag
tcctgcgtgccgcccgacgatggcctgcccctgcccctgcgcgggaagggcgcactgggc
cgggagctggaggcggagcccggccggctgcccctggagctggactgctccaagctctcc
ctgccccacttcagcagcatgagcccggagctctccatgaacggccacgcggccggctac
gagctctgcagcgcgctgagccggccctcgtccaagcagaacaccccccagtacctggcc
tccccgctggaccaggaggtcgtgccctgcacccccagccacggcagccggccgaggctc
gagaagctgtccgggctggccttgcctgactacacccggctctcgccggccaagctggtc
ctgaggcgccacctgagccaggaccacgcggtcagcagcaaggcggccgctggcgagctg
cacccgagagctgagcacgccaaggagaacggccttccctaccagagccctgtcatcgcc
aacgggatcaagctgagccctcaggaccctcggccctcatcccccgtggccttacagatg
acgggagagaagggcagcgagaagggcctgaaggagcgcgcctacgccagcagcggggag
gccatcaccagcctgcccgtgagcatcccgctcagcaccgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgctgcccagccgcgccgagaaggcgagaagcacc
cccagccctgtgccgcagccccgagactcctcatccacactggagaagcagccgggtgcc
ggtgcccatggtgccgcgagcagcgctgctggaggcagaggcctcgccctggcacctgcg
ggattctcctacgctggctccgtggccatcagtggggccctggcgggcagcccagcccca
ctcgctcctggagtcgagcccgccgcctttgacgagtcctccagctcggggagcctcttc
gccaccatggggtcccgcagctccacccctcagcagcctcccctgcttgtgcagccgcgg
aactccggctcagcctcacccgcccaccagctctgcgccagtccacggctcggcgccgcc
cagggtccgccccccgatgccggcaaggcagaccttccctgtgagtccggcctctccgac
ccggagagcgaggccaggaggagggtcgtcttcaccatctcggcaggtgcccccggctcc
aagcagtcgccttccagcaagcacagccccctgccctcgggtgcccgtggggacagcggc
cagagccacgggcaggacagccgcaagcggggcaggaggaagcgggcgtcggtggggacc
cccagcctcagctcgggtgtgtcccccaagcgccgggccctgccatccgtcgccggcctc
ttcacgcagtcttcagggtcccccctgaacctcaactccatggtcaacaacatcaaccag
cctctggaaatcacggccatctcgtctccagagagctccctgaagagctccccggtccct
taccaggacaatgaccagccgcccgtgctcaagaaggagaagcccctgagccagaccaac
ggggcccactactccccgctgacctcggacgaggagcagggctccgaggacgagcccggc
agcgccagaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccaaaa
accttggaaaacggtggcggcctggcggggaggaagccgacgcccgccggcgagcccgtc
aacagcagcaagtggaagtccaccttctccccgatctccgacctcggcctggccaaggcc
gccgacagcccgctgcaggccagctcctctctgagccagaactccctgttcgctttccgg
cccggcctggacgagcccggctcggctgacgccaagctggccgcccaccccaggaagagc
tttcccagcgccctggcaggggctggcgggctgagcccgagcagcacccctcccaacggc
ttcgccttcagcgggggcctggctgctgacctcagtgcacacagcttcagtgatggcgct
gctctctcccacaaggcccctgaggtggccggcctgggtgccgccccgagctttcccgca
ccgaggggcaaggaggccggtgccgcagagcctggctcatttgtgaacaagaggcagctg
gatggactgggtggcccgaagggcgaggggggcaagggcagggatgtgggcgagctgggc
ctgcccgtggtcgggccctcggacagggccttgctggtgcacagcaaggcgggcaagggc
cgcgaccgcgagcccgactccaagaatggccacaatctcttcatttctgctgccactgtg
cctcccgggggcctcctcagtggaccaggcctcgccacggtggcatcctcggcgggcagc
gcaacgccctctgcccagacgcaccgccccttcctgggctccttcacccccggcccgcag
ttcgccctgggccccatgtccctgcaggccaacctgggctcgtctgtgctgcagtccttg
ttcagctccgtgccggccgccgccggcctggtgcatgtctcgtccgccgcgaccagactg
accaactcgcacgccatgggcagcttctcctccggggtagcaggcggcgcagttggaggt
gtctttaaccacgcggtgccttccgcctctgctcatccgtttggagccagtttcgcgggc
agcggggccgcgtgtcgcagcgccacgctgagcttaaccccgctgcaggcggtggccgcc
acccccgcctcttcctttcaggccccggcctcggtggagtcgcggccgcccccacccccc
nngcccccgggccggccccccgcggggccgcccaccctgcccgcccccgccccgcctaac
gccgccttgcctcctcctcccgcgctgctcccggctaactccgagcttctgcagagcctc
gcgtccctccccgctaaccgagctttcttacctgcctcctctgccgcctccctgccgcct
gctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggccgcccgccccgcc
ctcaccgggccccgccagcccctgcccggcctggccctggcccgggcgcccgtgctcccg
caggccagctccacggggccgtccgccgtgtgggtttcccttggcatgccgcctccgtgt
gccgcgcgccttgcgggggttaagccgcgataa
DBGET
integrated database retrieval system
