KEGG   Equus asinus (ass): 106834431
Entry
106834431         CDS       T04645                                 
Symbol
PPP3CA
Name
(RefSeq) LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
eai  Equus asinus (ass)
Pathway
eai04010  MAPK signaling pathway
eai04020  Calcium signaling pathway
eai04022  cGMP-PKG signaling pathway
eai04114  Oocyte meiosis
eai04218  Cellular senescence
eai04310  Wnt signaling pathway
eai04360  Axon guidance
eai04370  VEGF signaling pathway
eai04380  Osteoclast differentiation
eai04625  C-type lectin receptor signaling pathway
eai04650  Natural killer cell mediated cytotoxicity
eai04658  Th1 and Th2 cell differentiation
eai04659  Th17 cell differentiation
eai04660  T cell receptor signaling pathway
eai04662  B cell receptor signaling pathway
eai04720  Long-term potentiation
eai04724  Glutamatergic synapse
eai04728  Dopaminergic synapse
eai04921  Oxytocin signaling pathway
eai04922  Glucagon signaling pathway
eai04924  Renin secretion
eai05010  Alzheimer disease
eai05014  Amyotrophic lateral sclerosis
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05031  Amphetamine addiction
eai05152  Tuberculosis
eai05163  Human cytomegalovirus infection
eai05166  Human T-cell leukemia virus 1 infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05170  Human immunodeficiency virus 1 infection
eai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eai05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106834431 (PPP3CA)
   04310 Wnt signaling pathway
    106834431 (PPP3CA)
   04370 VEGF signaling pathway
    106834431 (PPP3CA)
   04020 Calcium signaling pathway
    106834431 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    106834431 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    106834431 (PPP3CA)
   04218 Cellular senescence
    106834431 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    106834431 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    106834431 (PPP3CA)
   04660 T cell receptor signaling pathway
    106834431 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    106834431 (PPP3CA)
   04659 Th17 cell differentiation
    106834431 (PPP3CA)
   04662 B cell receptor signaling pathway
    106834431 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    106834431 (PPP3CA)
   04921 Oxytocin signaling pathway
    106834431 (PPP3CA)
   04924 Renin secretion
    106834431 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    106834431 (PPP3CA)
   04728 Dopaminergic synapse
    106834431 (PPP3CA)
   04720 Long-term potentiation
    106834431 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    106834431 (PPP3CA)
   04380 Osteoclast differentiation
    106834431 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106834431 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106834431 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    106834431 (PPP3CA)
   05163 Human cytomegalovirus infection
    106834431 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106834431 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    106834431 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106834431 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    106834431 (PPP3CA)
   05020 Prion disease
    106834431 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    106834431 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    106834431 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106834431 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:eai01009]
    106834431 (PPP3CA)
Enzymes [BR:eai01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     106834431 (PPP3CA)
Protein phosphatases and associated proteins [BR:eai01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     106834431 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 106834431
NCBI-ProteinID: XP_044622317
UniProt: A0A8C4MIB4
LinkDB
Position
3:complement(179493748..179776291)
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDVLKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSGNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcccaaggcaattgaccccaagttgtcgacgaccgacagggtggtgaaagct
gtcccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatgggaaa
cctcgagtggatgtcttaaaggcacatctcatgaaggaaggcagactggaagagagtgtt
gcattaagaataataacagaaggggcttcaatccttcgacaggagaaaaatttgctggat
attgatgcacccgtcacagtttgtggcgacatccatggacaattctttgacttgatgaag
ctctttgaagtggggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaagataaagtactcggaacgcgtctacgacgcctgcatggac
gccttcgactgcctgcccctggccgcgctcatgaaccagcagttcctgtgcgtccacggt
ggtttgtctccagagattaacactttggatgacatcagaaaattagaccgattcaaagaa
ccacctgcttatggacctatgtgtgatatcctgtggtcagaccccctggaggattttggc
aatgagaagactcaggaacatttcactcacaacacagtcagagggtgttcgtacttctac
agttacccggctgtttgtgaattcttacagcacaataacttgttgtctattctccgagcg
catgaagcccaagatgccgggtatcgcatgtacaggaaaagccaaacaacaggcttccct
tctctcattacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtcttgaagtatgagaacaacgtcatgaatatccggcagttcaactgttctcctcaccca
tactggcttccaaacttcatggatgttttcacttggtccctgccatttgttggggagaaa
gtgactgagatgctggtaaatgtcctcaacatctgctcagatgatgaactagggtcagaa
gaggacggatttgatggagcaacagctgccgcccggaaggaggtgataaggaacaaaatc
cgagcaataggcaaaatggccagagtgttctcagttctcagggaggagagcgagagcgtg
ctgacgctgaagggcctcacgcccaccggcatgctgcccagcggcgtgctctccggaggc
aagcagacgctgcagagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaggccaagggtttggaccgaattaac
gagaggatgccacctcgcagagacgccatgccctcggatgccaaccttaactccatcaac
aaggcgctcacctcagagactaacggcacggacagcaatggcagcaatagcggcaatatc
cagtga

DBGET integrated database retrieval system