Equus asinus (ass): 106836234 Help Entry 106836234         CDS       T04645                                  Symbol TSC2 Name (RefSeq) tuberin   KO K07207   tuberous sclerosis 2 Organism eai  Equus asinus (ass) Pathway eai04072   Phospholipase D signaling pathway eai04115   p53 signaling pathway eai04140   Autophagy - animal eai04150   mTOR signaling pathway eai04151   PI3K-Akt signaling pathway eai04152   AMPK signaling pathway eai04211   Longevity regulating pathway eai04218   Cellular senescence eai04714   Thermogenesis eai04910   Insulin signaling pathway eai04919   Thyroid hormone signaling pathway eai05163   Human cytomegalovirus infection eai05165   Human papillomavirus infection eai05168   Herpes simplex virus 1 infection eai05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:eai00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     106836234 (TSC2)    04151 PI3K-Akt signaling pathway     106836234 (TSC2)    04152 AMPK signaling pathway     106836234 (TSC2)    04150 mTOR signaling pathway     106836234 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     106836234 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     106836234 (TSC2)    04218 Cellular senescence     106836234 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     106836234 (TSC2)    04919 Thyroid hormone signaling pathway     106836234 (TSC2)   09149 Aging    04211 Longevity regulating pathway     106836234 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     106836234 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     106836234 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     106836234 (TSC2)    05163 Human cytomegalovirus infection     106836234 (TSC2)    05165 Human papillomavirus infection     106836234 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:eai01009]     106836234 (TSC2) Protein phosphatases and associated proteins [BR:eai01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      106836234 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Motif Other DBs NCBI-GeneID:  106836234 NCBI-ProteinID:  XP_044602578 LinkDB All DBs Position 14:8583362..8622247 Genome browser AA seq 1908 aa AA seqDB search MPDSYGLHIPAALAARSRDSTLAQSFGQRVAQNYDSQQALRRPLVSPRCRKCGSRFRRWL GAGVFPSLRRGGRGGWRCAGHRGVLRAPLPTMAKPASKDSGLKEKFKTLLGLGTPRPNPR TAEGRQTEFIITAEILRELSVECGLNNRIRVIGQICEVAKTKKFEEHAVEALWKAVADLL QPERPPEARHAVLALLKAIVQGQGDRLGILRALFFKVIKDYPSNEDLHERLEVFKALTDN GKHITYLEEELAEFVLQWMDIGLSSEFLLVLVNLVKFNSCYLDEYIASMVHMICLLCVQT VSSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLG HSAIYNMCRLMENRAYMEDAPLLRGAVFFVGMALWGAHRLYTLKNSPTSVLPSFYEAMTC PNEVVSYEIVLSITRLIKKYRRELQAVTWDILLNIIERLLQQLQSLDSPKLRTIVHDLLT TVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLITYRAQSIHPAKDGWIHNLQLLM ERFFRNESRSAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLAT QLLVDLAEGCHTHHFNSLLGTIFSLKVIARSLSPPPELEERDLEAYSASLEDVKTAVLGL LVILQTKLYTLPASHAMRVYETLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLH RLGLPNKDGVVRFSPYCLCDYMEPERGSEKKASGPLSPPTGPPGPASPGPATRPGSLPYS LLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIFNSPCSVDQLSSALCSMLSGPKTL ERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVA LAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLPHLYRNFAAEQYAS VFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDT PEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAADAFRCRSISVSEHVV RSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPV GEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQGCPELSSDPSVHVRQTKE APAKLESQAGQQVCRGARDRVRSMSGGHGLRVGALDASASHFPGGLTSPGPQTTPASKPE KASAGTQLPAQKEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNM PLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPSPPPRSNTVASFFSLYQSSCQGK LHRSISWADSAVVLEEGSPGEANVPVEPPDLEDFEATLGTDRRCPRTEAYSRSSSTSSQE EKSFRGEELAVGGIPIERAVSSEGARPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGD KADVGRLSPEVKARSQSGILDGEGAAWSVPGEESQGQSPAQPESPLPSSCPRSPSGLRPR GYTISDSAPSRRGKRVEREAFKSRAGASNTEKVPGINPSFVFLQLYHSPFFGDESNKPIL LPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSTSELAILSNEHGSYRYTEFLTGLGKL IELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHL GNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECNLVSLQCRKDMEGLVDTSVAK IVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRHRIREEAQYS NSSLPLMQTHPPGHAKAPAQAPAEPMPTYETGQRKRLISSVDDFTEFV NT seq 5727 nt NT seq  +upstreamnt  +downstreamnt atgcctgactcctacggactacacatcccggcggccctcgcggcccggtcacgtgactcg accctcgctcagtcattcggtcagagggtggcccagaactacgactcccagcaagccctg cggcggcccttggtgtcgccccgctgccggaagtgcgggtcccgcttccggcggtggctt ggggccggggtcttcccgtctctccgtaggggcggccggggcggctggcgctgcgcgggg cacagaggagtcctccgggcgcccctgcccaccatggccaagccagcaagcaaagattca ggcttgaaggagaagttcaagactctgctgggactgggaactccgaggccaaatcccagg actgcagagggcagacagacagagttcatcatcacggcggaaatcctgagagaactgagt gttgaatgtggcctcaacaatcgtatccgggtgataggacagatctgtgaagtcgcaaaa acgaagaaatttgaagagcacgcagtggaagcactctggaaggccgtcgcagacctgctg cagcctgagcggccacctgaagcccggcacgcagtgctggctctgctgaaggccatcgtg caggggcagggggaccgcttgggcattctcagggccctcttctttaaagtcatcaaggat tacccctctaatgaagacctccacgaaagactggaagttttcaaggccctcacggacaat gggaaacacatcacctacttggaagaagaactggctgagtttgtcctgcagtggatggac atcggcctgtcctcagaattcctgctggtgcttgtgaacttggtcaaattcaacagctgt tacctcgatgaatacatcgcatcgatggtccacatgatctgcctgctgtgcgtccagacc gtgtcctctgtggacatagaggtctctctgcaggtgctggatgccgtggtctgctacaac tgcctgccggccgagagcctccccctcttcatcgtcaccctctgccgcaccatcaatgtc aaggagctctgtgagccttgctggaagctgatgcggaacctcctgggcacccacctgggc cacagtgccatctacaacatgtgccgcctcatggagaacagagcctacatggaggacgcc ccgctgctgagaggagctgtgttctttgttggcatggctctatggggagcccaccggctc tatactctcaagaactccccgacgtccgtgctgccatcgttctatgaggccatgacctgt ccgaatgaggtggtgtcctatgagattgtcctctccataacaagactcatcaagaagtac aggagggagcttcaggctgtgacgtgggacatcctgctgaacattattgaacgcctgctt cagcagctccagagcctggacagcccgaaactcaggaccatcgtccatgacctgctgacc acggtggaagaactgtgtgatcagaatgagttccacggctcccaggagagatactttgag cttgttgagagatgtgcagaccagaggcctgagtcctccctcttaaacttaataacctac agggctcagtcaatccatcctgcaaaggacggctggattcacaacctacagttactgatg gagagattcttcaggaacgaatctcgcagcgctgtgcgcatcaaggtgctggatgtcctg tccttcgtgttgctcatcaacaggcagttctacgaggaggagctgatcaactcagtggtc atctcacagctctcccacatccctgaggataaagaccaccaggtccgaaagctggccacc cagctgctggtggacctggccgaaggctgccatacccaccacttcaacagcctgttgggg acaatcttctctctaaaggtgattgcccgctccctctccccgccccccgagctggaggaa agagacctggaggcatactcagcctccttggaagatgtgaagaccgcggtcctggggctc ctggtcatccttcagaccaagctgtacaccttgcctgccagccacgcaatgcgtgtgtac gagacgcttgtcagccacatccagctccactacaagcacagctacaccctgcccattgcc agcagcatccggctacaggccttcgatttcctgctgctgctgcgggccgactcgttgcac cgcctcggtctgcccaacaaggacggggttgtgaggttcagcccctattgcctctgtgac tacatggagccggagagaggctctgagaagaaggccagtggtcccttgtcacctcccacc gggccgcctggcccagcgtctccaggccccgccacacggcccggctctctgccctactct ctcctcttccgtgtcctgctgcagtgcttgaagcaggagaccgactggaaggtgctgaag cttgtgctcagcaagctccctgagtcactgcgctataaggtcctcattttcaactctcca tgcagtgttgaccagctgtcctccgccctctgctctatgctttcaggtcccaagaccctc gagcggctccgaggcaccccagaagggttctctagaaccgacctgcatttggctgtggtt cccgtgctgacggcgctaatctcttaccacaactacctggataaaaccagacagcgggag atggtatactgcctggagcaaggcctcatctaccgctgcgccagccagtgtgtggtggcc ctggccatctgcagcgtggagatgccagatatcatcatcaaagcgttgcctgtcttggtc gtgaaactcacgcacatctcggccacagccagcatggccattccactcctcgagttcctg tcgactctggccaggctgcctcacctctacaggaacttcgccgcagagcagtacgcgagc gtgttcgccatctccctgccgtataccaacccctctaagttcaaccagtacattgtgtgc ctggcccatcatgtcatagccatgtggttcattaggtgccgcctgcccttccggaaagat tttgttccttacatcactaagggcctgcgctccaatgtcctcctgtcttttgatgacacc cctgagaaggacagcttcagagcacggagcaccagtctcaacgagaggccgaagagtttg aggatagccagaccccccaaacaaggcttgaataactctccacctgtgaaagaattcaag gagagctctgcagccgatgccttccggtgccgcagcatcagtgtgtctgaacatgtggtc cgcagcaggatccagacatccctcacgagtgccagcttggggtctgcagatgagaactca atggcccaggctgatgacaacttgaaaaatctccacttggagctcacagaaacgtgtctg gacatgatggccagatatgtgttctccaacttcacagcggtccccaagaggtcccccgtg ggagagttcctcctggctggcggcaggaccaaaacctggctggttgggaacaagcttgtc accgtgacaacgagtgtggggactggtacccggtcactgctgggcctggactcaggagag ctgcagggctgcccagagttaagctccgaccccagtgtgcacgtgagacagacaaaggag gcgccagccaagctggagtcccaggctgggcagcaggtgtgccgcggggcccgggaccgg gtccgctccatgtctgggggccatggccttcgcgttggtgccctggatgcttcagcctcc cacttcccaggcggcctcacttccccgggcccacagaccacaccagccagcaagcctgag aaggcctcagctggcacccagctcccagcgcagaaggagaagacgaacctggcagcctat gtgcccttgctgacccagggctgggctgagatcttggtccggaggcccacagggaacacc agctggctgatgagcctggagaacccgctcagccccttctcctcggacatcaacaacatg cctctgcaggagctctccaacgccctgatggccgctgagcgcttcaaggagcgccgcgac acggccctgtacaagtcactgtcagtgccagcagctggctcagccaagccttccccaccc ccacggtctaacacagtggcctctttcttctccctgtaccagtccagttgccaaggaaag ctgcacaggagcatttcctgggcagactctgcggtggttctggaggagggaagtccaggc gaggctaatgtgccagtggaaccccccgacttagaggacttcgaggcaacactcggcaca gacaggcgctgtccgcgcactgaagcttacagcaggtcgtcttcaacctccagccaggag gagaagtcattccgtggagaggagttggctgttggggggatccccatcgagcgggccgtc tcctctgagggagcccggccctctgtggacctctccttccagccctcacagcccctaagc aagtccagctcctcacctgaactgcagaccctgcaggacatccttggggaccctggggac aaggctgacgttggccggctgagccccgaggtcaaggcccggtcacagtctgggatcctg gatggggaaggcgctgcctggtcagtcccaggcgaagagagccagggccagagccctgct cagcccgagagtcccttgccttccagctgcccccgctcccccagtggcctgcggccccga ggctacaccatctctgattcagccccttcacgcaggggcaagagggtggagagggaagcc ttcaagagcagagctggggcctctaatactgagaaggtgccgggcatcaaccccagcttc gtgttcctgcagctctaccattcgcctttcttcggcgacgagtccaacaagccaatcctt ttgcctaacgagtccttcgagcgatcggtgcagctccttgaccagatcccatcctacgac acacacaagattgccgtcctgtacgtgggagaaggccagagcaccagtgagctcgccatc ctgtccaatgagcacggctcctacaggtacacggagttcctgacaggcctgggcaagctc atcgagctcaaggactgccagccagataaggtgtacctgggcggcctggatgtgtgtggc gaggatggccagttcacctactgctggcacgacgacatcatgcaagccgtcttccacatc gccaccctgatgcccaccaaggacgtggacaagcaccgttgcgacaagaagcgccacctg ggcaatgatttcgtgtccattgtctacaacgactctggcgaggacttcaagctgggcacc atcaaaggccagttcaactttgtccatgtgattatcacccccctggactacgagtgcaac ctggtgtcgctgcagtgcaggaaagacatggagggccttgtggacaccagcgtggccaag atcgtgtctgaccgcaacctcccttttgtggcccgccagatggccctgcatgcaaatatg gcctcgcaggtacaccacagccgctccaaccccactgacatctatccctccaagtggatt gccaggctccgccacatcaagcggctccgccaccggatccgggaggaagcccagtactcg aactccagcctgcccctgatgcagacgcaccctccgggccacgccaaagccccagcacag gctccagccgagcccatgcccacctatgagacgggccagcggaagcgcctcatctcttcc gtggacgacttcacagagtttgtgtga

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