Equus asinus (ass): 106836604
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Entry
106836604 CDS
T04645
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
eai
Equus asinus (ass)
Pathway
eai01521
EGFR tyrosine kinase inhibitor resistance
eai01522
Endocrine resistance
eai04010
MAPK signaling pathway
eai04014
Ras signaling pathway
eai04015
Rap1 signaling pathway
eai04066
HIF-1 signaling pathway
eai04068
FoxO signaling pathway
eai04081
Hormone signaling
eai04114
Oocyte meiosis
eai04140
Autophagy - animal
eai04144
Endocytosis
eai04150
mTOR signaling pathway
eai04151
PI3K-Akt signaling pathway
eai04152
AMPK signaling pathway
eai04211
Longevity regulating pathway
eai04213
Longevity regulating pathway - multiple species
eai04510
Focal adhesion
eai04518
Integrin signaling
eai04519
Cadherin signaling
eai04520
Adherens junction
eai04550
Signaling pathways regulating pluripotency of stem cells
eai04730
Long-term depression
eai04913
Ovarian steroidogenesis
eai04914
Progesterone-mediated oocyte maturation
eai05200
Pathways in cancer
eai05202
Transcriptional misregulation in cancer
eai05205
Proteoglycans in cancer
eai05214
Glioma
eai05215
Prostate cancer
eai05218
Melanoma
eai05224
Breast cancer
eai05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106836604 (IGF1R)
04014 Ras signaling pathway
106836604 (IGF1R)
04015 Rap1 signaling pathway
106836604 (IGF1R)
04066 HIF-1 signaling pathway
106836604 (IGF1R)
04068 FoxO signaling pathway
106836604 (IGF1R)
04151 PI3K-Akt signaling pathway
106836604 (IGF1R)
04152 AMPK signaling pathway
106836604 (IGF1R)
04150 mTOR signaling pathway
106836604 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
106836604 (IGF1R)
04518 Integrin signaling
106836604 (IGF1R)
04519 Cadherin signaling
106836604 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
106836604 (IGF1R)
04140 Autophagy - animal
106836604 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
106836604 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
106836604 (IGF1R)
04520 Adherens junction
106836604 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
106836604 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
106836604 (IGF1R)
04914 Progesterone-mediated oocyte maturation
106836604 (IGF1R)
09156 Nervous system
04730 Long-term depression
106836604 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
106836604 (IGF1R)
04213 Longevity regulating pathway - multiple species
106836604 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106836604 (IGF1R)
05202 Transcriptional misregulation in cancer
106836604 (IGF1R)
05205 Proteoglycans in cancer
106836604 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
106836604 (IGF1R)
05214 Glioma
106836604 (IGF1R)
05218 Melanoma
106836604 (IGF1R)
05215 Prostate cancer
106836604 (IGF1R)
05224 Breast cancer
106836604 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106836604 (IGF1R)
01522 Endocrine resistance
106836604 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
eai01001
]
106836604 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
eai04090
]
106836604 (IGF1R)
Enzymes [BR:
eai01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
106836604 (IGF1R)
Protein kinases [BR:
eai01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
106836604 (IGF1R)
CD molecules [BR:
eai04090
]
Proteins
106836604 (IGF1R)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
106836604
NCBI-ProteinID:
XP_014705088
UniProt:
A0A8C4PRR4
LinkDB
All DBs
Position
2
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYFYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAEGSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQIANTTMSSRSRNTTMADTYNVTDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKTTYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMESGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactaccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaagcagaggactaccgcagctaccgcttccccaagctcacggtc
atcactgaatacttgctgctgttccgcgtggccggcctcgagagccttggtgacctcttc
ccaaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaagatattgggctttacaacctgaggaacatcactcggggggcc
atcaggattgagaaaaatgctgacctttgttacctctccacggtggactggtccctgatc
ctggatgcagtgtccaataactacatcgtgggaaacaaacccccaaaagaatgcggggac
ctgtgtccagggacaatggaggagaagccattgtgcgagaagaccaccatcaacaacgag
tacaactaccgctgctggactacaaatcgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgcgtcgcctgccgccactacttctacgccggcgtctgc
gtgcccacctgcccgcccaacacctatcgctttgagggctggcgctgcgtggaccgcgac
ttctgtgccaacatccccagcgctgagggcagcgactccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcggggttcatccgcaacggcagtcagagcatgtat
tgcatcccttgtgaaggtccttgccccaaagtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcaaatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaatatccgacgaggcaataacattgcctcggaactggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttagtctccttgtcc
ttcctgaaaaacctccgccagatcttaggagaggaacagctggaggggaattactccttc
tacgtcctcgacaaccagaacttacagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtacttcgctttcaatcccaaattgtgtgtctccgaaatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacatcaacaccagg
aacaacggagagagagcctcctgtgagagtgatgtcctgcacttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcatcgctaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaagaggcaccctttaaaaacgtcacagagtatgatggg
caggatgcctgtggctccaacagctggaacatggtggatgtggacctccctcccaacaag
gacgtcgagcctggcattctactgcacgggctgaagccctggacgcagtacgccgtttac
gtcaaggccgtgactctcaccatggtagagaacgaccacattcgtggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccatccccctggatgttctttcagca
tcaaactcctcttctcagctaattgtgaagtggaacccaccctctctgcccaacggcaac
ctgagttactacatcgtgagatggcagcgacagcctcaggacagctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgatgtt
gaagaggtgacggagaatcccaagaccgaagtgtgtggtggagagaaagggccttgctgt
gcttgccccaaaaccgaagccgagaagcaggccgagaaggaggaagccgagtaccgcaaa
gtctttgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcatgcagattgccaacactaccatgtccagccgaagcaggaacaccacgatggca
gacacctacaatgtcacagacccagaggagctggagacagaataccctttctttgagagc
agagtggacaacaaggagaggactgtcatttctaacctccggccattcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctaggctgcagtgcctccaacttc
gtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagccaaggcctgaaaattccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgagaatgtgta
tccagacaggagtacaggaagtatggaggggccaagcttaaccggctcaaccctgggaac
tatacggcccggatccaggccacctctctctctggaaatgggtcgtggactgatcctgtg
ttcttctatgtcccggccaaaacgacatatgaaaatttcatccatctgataattgctctg
cctgttgccgtcctgttgatagtgggagggttggttataatgttgtacgtcttccataga
aaaagaaataacagcaggctggggaatggagtgctgtatgcatctgtgaacccagagtac
ttcagcgcagccgatgtgtatgtccctgatgagtgggaggtcgctcgggagaagatcacc
atgagccgagagctgggacagggctcctttgggatggtatatgaaggagttgccaagggc
gtggtcaaagatgagcctgaaaccagagtggccattaaaacggtgaacgaggctgcaagc
atgcgtgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccaacgctggtcatcatggag
ctgatgacacggggggatctcaaaagttatctcaggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagagattgca
gacggcatggcatacctcaatgccaacaagttcgtccacagagaccttgccgcccggaac
tgcatggtggccgaagatttcacagtcaaaattggagattttggtatgacgagagatatc
tatgagacagactattaccggaaaggagggaagggattgctgcctgtgcgctggatgtcg
cccgagtccctcaaggatggagtcttcaccactcattctgacgtctggtcctttggggtt
gtcctctgggagattgccacgctggccgagcagccataccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctagacaagccggacaactgccctgacatg
ctgtttgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagtctggctttcgggaggtctccttctac
tatagcgaggagaacaagccacccgagccagaggagctggacctggagccggagaacatg
gagagtgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccaggccctggcgtgctggttctccgagccagcttt
gatgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
