KEGG   Equus asinus (ass): 106839421
Entry
106839421         CDS       T04645                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X2
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
eai  Equus asinus (ass)
Pathway
eai01522  Endocrine resistance
eai04010  MAPK signaling pathway
eai04012  ErbB signaling pathway
eai04014  Ras signaling pathway
eai04024  cAMP signaling pathway
eai04068  FoxO signaling pathway
eai04071  Sphingolipid signaling pathway
eai04137  Mitophagy - animal
eai04140  Autophagy - animal
eai04141  Protein processing in endoplasmic reticulum
eai04210  Apoptosis
eai04215  Apoptosis - multiple species
eai04217  Necroptosis
eai04310  Wnt signaling pathway
eai04380  Osteoclast differentiation
eai04510  Focal adhesion
eai04530  Tight junction
eai04620  Toll-like receptor signaling pathway
eai04621  NOD-like receptor signaling pathway
eai04622  RIG-I-like receptor signaling pathway
eai04625  C-type lectin receptor signaling pathway
eai04657  IL-17 signaling pathway
eai04658  Th1 and Th2 cell differentiation
eai04659  Th17 cell differentiation
eai04660  T cell receptor signaling pathway
eai04664  Fc epsilon RI signaling pathway
eai04668  TNF signaling pathway
eai04722  Neurotrophin signaling pathway
eai04723  Retrograde endocannabinoid signaling
eai04728  Dopaminergic synapse
eai04750  Inflammatory mediator regulation of TRP channels
eai04910  Insulin signaling pathway
eai04912  GnRH signaling pathway
eai04914  Progesterone-mediated oocyte maturation
eai04917  Prolactin signaling pathway
eai04920  Adipocytokine signaling pathway
eai04926  Relaxin signaling pathway
eai04930  Type II diabetes mellitus
eai04931  Insulin resistance
eai04932  Non-alcoholic fatty liver disease
eai04933  AGE-RAGE signaling pathway in diabetic complications
eai04935  Growth hormone synthesis, secretion and action
eai04936  Alcoholic liver disease
eai05010  Alzheimer disease
eai05012  Parkinson disease
eai05016  Huntington disease
eai05017  Spinocerebellar ataxia
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05132  Salmonella infection
eai05133  Pertussis
eai05135  Yersinia infection
eai05142  Chagas disease
eai05145  Toxoplasmosis
eai05152  Tuberculosis
eai05161  Hepatitis B
eai05162  Measles
eai05166  Human T-cell leukemia virus 1 infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05169  Epstein-Barr virus infection
eai05170  Human immunodeficiency virus 1 infection
eai05171  Coronavirus disease - COVID-19
eai05200  Pathways in cancer
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05210  Colorectal cancer
eai05212  Pancreatic cancer
eai05231  Choline metabolism in cancer
eai05415  Diabetic cardiomyopathy
eai05417  Lipid and atherosclerosis
eai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    106839421 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106839421 (MAPK10)
   04012 ErbB signaling pathway
    106839421 (MAPK10)
   04014 Ras signaling pathway
    106839421 (MAPK10)
   04310 Wnt signaling pathway
    106839421 (MAPK10)
   04668 TNF signaling pathway
    106839421 (MAPK10)
   04068 FoxO signaling pathway
    106839421 (MAPK10)
   04071 Sphingolipid signaling pathway
    106839421 (MAPK10)
   04024 cAMP signaling pathway
    106839421 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    106839421 (MAPK10)
   04137 Mitophagy - animal
    106839421 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    106839421 (MAPK10)
   04215 Apoptosis - multiple species
    106839421 (MAPK10)
   04217 Necroptosis
    106839421 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106839421 (MAPK10)
   04530 Tight junction
    106839421 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106839421 (MAPK10)
   04621 NOD-like receptor signaling pathway
    106839421 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    106839421 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    106839421 (MAPK10)
   04660 T cell receptor signaling pathway
    106839421 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    106839421 (MAPK10)
   04659 Th17 cell differentiation
    106839421 (MAPK10)
   04657 IL-17 signaling pathway
    106839421 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    106839421 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106839421 (MAPK10)
   04920 Adipocytokine signaling pathway
    106839421 (MAPK10)
   04912 GnRH signaling pathway
    106839421 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    106839421 (MAPK10)
   04917 Prolactin signaling pathway
    106839421 (MAPK10)
   04926 Relaxin signaling pathway
    106839421 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    106839421 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    106839421 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    106839421 (MAPK10)
   04722 Neurotrophin signaling pathway
    106839421 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    106839421 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106839421 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106839421 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    106839421 (MAPK10)
   05231 Choline metabolism in cancer
    106839421 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    106839421 (MAPK10)
   05212 Pancreatic cancer
    106839421 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106839421 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    106839421 (MAPK10)
   05161 Hepatitis B
    106839421 (MAPK10)
   05171 Coronavirus disease - COVID-19
    106839421 (MAPK10)
   05162 Measles
    106839421 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106839421 (MAPK10)
   05169 Epstein-Barr virus infection
    106839421 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106839421 (MAPK10)
   05135 Yersinia infection
    106839421 (MAPK10)
   05133 Pertussis
    106839421 (MAPK10)
   05152 Tuberculosis
    106839421 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106839421 (MAPK10)
   05142 Chagas disease
    106839421 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106839421 (MAPK10)
   05012 Parkinson disease
    106839421 (MAPK10)
   05016 Huntington disease
    106839421 (MAPK10)
   05017 Spinocerebellar ataxia
    106839421 (MAPK10)
   05020 Prion disease
    106839421 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    106839421 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106839421 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    106839421 (MAPK10)
   05415 Diabetic cardiomyopathy
    106839421 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    106839421 (MAPK10)
   04936 Alcoholic liver disease
    106839421 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    106839421 (MAPK10)
   04931 Insulin resistance
    106839421 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    106839421 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    106839421 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eai01001]
    106839421 (MAPK10)
Enzymes [BR:eai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     106839421 (MAPK10)
Protein kinases [BR:eai01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   106839421 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 106839421
NCBI-ProteinID: XP_014709628
UniProt: A0A9L0IWM5
LinkDB
Position
3:complement(166264648..166561273)
AA seq 464 aa
MSLHLLYYCSEPTFDVKIAFCQGFHKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttcgatgtgaaaattgccttt
tgtcagggattccataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagcgtggaagtgggagactcaaccttcaccgtt
ctcaagcgctaccagaatctaaagcctattggctctggcgctcagggaatagtttgtgct
gcgtatgatgctgttctggacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaatcat
aaaaatattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccag
gatgtttacttagtaatggaactgatggacgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctc
cactctgctggcattattcacagggatttaaaaccaagtaacattgtcgtgaagtctgat
tgtacgttgaaaatcctcgactttggactggccaggacggcaggcaccagcttcatgatg
actccttatgtggtgacccgttattacagagcccccgaggtcatcctggggatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgaacaactagga
acaccctgtccggaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgcta
gtgattgacccagcaaaaaggatatctgtggacgacgccttacagcatccatacatcaat
gtgtggtacgaccctgccgaagtggaggcgcctccacctcagatatatgacaaacagttg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaagtaatgaat
tcagaagagaagactaaaaatggtgttgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccgtcctcgtccgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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