Equus asinus (ass): 106839506
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Entry
106839506 CDS
T04645
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
eai
Equus asinus (ass)
Pathway
eai01521
EGFR tyrosine kinase inhibitor resistance
eai01522
Endocrine resistance
eai04010
MAPK signaling pathway
eai04012
ErbB signaling pathway
eai04014
Ras signaling pathway
eai04062
Chemokine signaling pathway
eai04068
FoxO signaling pathway
eai04072
Phospholipase D signaling pathway
eai04150
mTOR signaling pathway
eai04151
PI3K-Akt signaling pathway
eai04510
Focal adhesion
eai04540
Gap junction
eai04630
JAK-STAT signaling pathway
eai04650
Natural killer cell mediated cytotoxicity
eai04660
T cell receptor signaling pathway
eai04662
B cell receptor signaling pathway
eai04664
Fc epsilon RI signaling pathway
eai04714
Thermogenesis
eai04722
Neurotrophin signaling pathway
eai04810
Regulation of actin cytoskeleton
eai04910
Insulin signaling pathway
eai04912
GnRH signaling pathway
eai04915
Estrogen signaling pathway
eai04917
Prolactin signaling pathway
eai04926
Relaxin signaling pathway
eai04935
Growth hormone synthesis, secretion and action
eai05034
Alcoholism
eai05160
Hepatitis C
eai05161
Hepatitis B
eai05163
Human cytomegalovirus infection
eai05165
Human papillomavirus infection
eai05200
Pathways in cancer
eai05205
Proteoglycans in cancer
eai05206
MicroRNAs in cancer
eai05207
Chemical carcinogenesis - receptor activation
eai05208
Chemical carcinogenesis - reactive oxygen species
eai05210
Colorectal cancer
eai05211
Renal cell carcinoma
eai05213
Endometrial cancer
eai05214
Glioma
eai05215
Prostate cancer
eai05220
Chronic myeloid leukemia
eai05221
Acute myeloid leukemia
eai05223
Non-small cell lung cancer
eai05224
Breast cancer
eai05225
Hepatocellular carcinoma
eai05226
Gastric cancer
eai05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
106839506 (SOS2)
04012 ErbB signaling pathway
106839506 (SOS2)
04014 Ras signaling pathway
106839506 (SOS2)
04630 JAK-STAT signaling pathway
106839506 (SOS2)
04068 FoxO signaling pathway
106839506 (SOS2)
04072 Phospholipase D signaling pathway
106839506 (SOS2)
04151 PI3K-Akt signaling pathway
106839506 (SOS2)
04150 mTOR signaling pathway
106839506 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
106839506 (SOS2)
04540 Gap junction
106839506 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
106839506 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
106839506 (SOS2)
04660 T cell receptor signaling pathway
106839506 (SOS2)
04662 B cell receptor signaling pathway
106839506 (SOS2)
04664 Fc epsilon RI signaling pathway
106839506 (SOS2)
04062 Chemokine signaling pathway
106839506 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
106839506 (SOS2)
04912 GnRH signaling pathway
106839506 (SOS2)
04915 Estrogen signaling pathway
106839506 (SOS2)
04917 Prolactin signaling pathway
106839506 (SOS2)
04926 Relaxin signaling pathway
106839506 (SOS2)
04935 Growth hormone synthesis, secretion and action
106839506 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
106839506 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
106839506 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
106839506 (SOS2)
05206 MicroRNAs in cancer
106839506 (SOS2)
05205 Proteoglycans in cancer
106839506 (SOS2)
05207 Chemical carcinogenesis - receptor activation
106839506 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
106839506 (SOS2)
05231 Choline metabolism in cancer
106839506 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
106839506 (SOS2)
05225 Hepatocellular carcinoma
106839506 (SOS2)
05226 Gastric cancer
106839506 (SOS2)
05214 Glioma
106839506 (SOS2)
05221 Acute myeloid leukemia
106839506 (SOS2)
05220 Chronic myeloid leukemia
106839506 (SOS2)
05211 Renal cell carcinoma
106839506 (SOS2)
05215 Prostate cancer
106839506 (SOS2)
05213 Endometrial cancer
106839506 (SOS2)
05224 Breast cancer
106839506 (SOS2)
05223 Non-small cell lung cancer
106839506 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
106839506 (SOS2)
05160 Hepatitis C
106839506 (SOS2)
05163 Human cytomegalovirus infection
106839506 (SOS2)
05165 Human papillomavirus infection
106839506 (SOS2)
09165 Substance dependence
05034 Alcoholism
106839506 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
106839506 (SOS2)
01522 Endocrine resistance
106839506 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
IQ_SEC7_PH
PH_13
RHG20_PH
PH_10
Motif
Other DBs
NCBI-GeneID:
106839506
NCBI-ProteinID:
XP_044621536
UniProt:
A0A8C4LRA7
LinkDB
All DBs
Position
2:complement(229734144..229822750)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPRWRGLLVPALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRHPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFREAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTKIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECRHAFELVSKDENSITFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEMYRFVVKDSEENIVFEDSLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQTQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRVIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSSSEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKISFSRIAEAELGSAV
SAPTSPNTPSTPPASAASDLSVFPDVDLSASCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
DGPLTPPPLPPRKKFDHDASNPKGNMKSDDDPPAIPPRQPPPPKVKPRVPAPSGAFEGSL
HSPPPPPPREPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTRPDSPN
TPPSTPSPRVPRRCCVLSSSHSNLTYPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPMY
RLSLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaggagaacagcccgagatggcgg
gggctgctggtgccggccctgcggaaggttcaggagcaggtacatcccaatctctcagct
aatgaagaatctctctattacattgaagagctgatttttcaactgcttaataaattatgc
atggctcagccaaggactgttcaagatgtggaggaacgagttcaaaagacctttccgcat
ccaattgataaatgggctattgctgatgcacaatccgccatagagaaacgaaaacgaaga
caccctctcttactgcctgtggacaaaatccatccttcattgaaggaggttttagggtac
aaagtggactaccatgtgtccctgtatattgtggctgtactggagtatatctcagctgat
attttaaaattggctggtaattatgtttttaatattcgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgagccgagttcttcaggtgaattgaattactat
gaccttgtcagaactgaaattgcagaagaaagacagtatctccgggaactaaatatgatc
ataaaagtatttcgagaagcctttctttctgacagaaagctgtttaaaccttctgatatt
gagaagattttcagtaacattttagatatacatgaattgactgtgaaacttctaggtttg
attgaggacacagttgagatgactgatgaaagcagtcctcatcccttagctggcagctgt
ttcgaagatttggcagaagagcaggcttttgatccttatgaaacattatcacaggacatc
ctttcaccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatgggttcagagaggcagttcgttatgtccttccacgcctg
atgcttgtgccagtgtatcattgttggcactacttcgaattattaaagcaattgaaagca
tgtagtgaagaacaagaagacagagaatgtttgaaccaagctattactgctctcatgaat
ctccagggtagtatggaccgaatttataagcagtattcgcctagacgtcgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcacctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagacatcggacagtgttgtaat
gaattcattatggaaggtcctttgacaaaaattggtgctaaacatgaacggcatattttt
ctctttgatggcttaatgattagctgcaaacccaatcatagccagtcgcggcttccaggg
tacagtagtgcagaatacagactgaaagagaagtttgtcatgaggaaaatacaaatatgt
gataaagaagacacttgcgagtgcagacatgcttttgaattagtctccaaagatgaaaac
agcatcacatttgctgccaagtctgccgaagagaagaataactggatggcagcactcatt
tctcttcattaccgtagcacactggaccgaatgctggactcagtgttactgaaggaagaa
aatgagcagccactgaggttaccaagtcctgagatgtatcgtttcgtggtgaaagactct
gaggaaaacatagtttttgaagacagcttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttgacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacatatcgttcattttgtaaaccacaggaattgctaagc
ttactaattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgagcagcccatcagtgcagaccttaaaaggtttcgcaaggaatacgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacaccatttttat
gattttgaaagagatttggagttgcttgaacggctagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtctattgctaagatcatcaagaggaagaaacag
actcaggcaaacggaataagccataatatcacctttgaaagcccaccccccccgattgaa
tggcacatcagcagacccgggcagttcgagacctttgatctcatgacacttcatccaata
gaaattgcacgccagctgacgcttttggaatctgatctctataggaaagtccagccttct
gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccacaccacaaatctcaccctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgagtggcagtactaagtagagttatagaaattctgcaagttttt
caagatttgaataatttcaatggcgtactggagatagtcagtgcagtgaattcagtgtca
gtgtacagactagaccataccttcgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagagatgaggcggttctttgaaaaccttaaccccatgggaagttcttctgaa
aaagagtttacggattatttgttcaacaaatcactagaaattgaaccccgcaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aacacgggccgacatggctctacctcaggcactttacgaggtcatcccaccccgttagaa
agagaaccgtgtaaaatcagctttagtcggattgctgaggctgagctgggatcagcagtg
tcggcaccaacctctcccaacacgccgtccaccccgccggcgtctgctgcttcagacctc
agtgtgttcccagacgtggacctcagcgcttcctgtggcagcaatagcatctttgctcca
gtcctcttgccacactcaaagtccttcttcagctcatgcggtagtttacataaactaagt
gacgggcccctgactcctcctccgcttcctcctcggaagaagtttgatcacgatgcttcg
aatcccaagggaaatatgaaatctgatgatgaccctcctgctattccaccaagacaacct
cctcctccaaaggtgaaacccagagttcctgctccttctggtgcatttgaggggtctctg
cacagcccacctccaccgccgcccagagagcctcttcctgacacgcctccaccggttccc
cttcggcctccagaacactttataaactgtccgtttaatcttcagccacctcccctggga
catcttcacagagatccagactggttcagagacgttagcacacgaccagattcgcccaac
actcctcccagcacaccgtctccacgggtgccacgtcgatgctgtgtgctcagttctagt
cacagtaatctcacttatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaccccccaatgtac
agactgtctttgctagaaaacgcggaaactcctcaatga
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