KEGG   Equus asinus (ass): 106842388
Entry
106842388         CDS       T04645                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X3
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
eai  Equus asinus (ass)
Pathway
eai04010  MAPK signaling pathway
eai04020  Calcium signaling pathway
eai04022  cGMP-PKG signaling pathway
eai04114  Oocyte meiosis
eai04218  Cellular senescence
eai04310  Wnt signaling pathway
eai04360  Axon guidance
eai04370  VEGF signaling pathway
eai04380  Osteoclast differentiation
eai04625  C-type lectin receptor signaling pathway
eai04650  Natural killer cell mediated cytotoxicity
eai04658  Th1 and Th2 cell differentiation
eai04659  Th17 cell differentiation
eai04660  T cell receptor signaling pathway
eai04662  B cell receptor signaling pathway
eai04720  Long-term potentiation
eai04724  Glutamatergic synapse
eai04728  Dopaminergic synapse
eai04921  Oxytocin signaling pathway
eai04922  Glucagon signaling pathway
eai04924  Renin secretion
eai05010  Alzheimer disease
eai05014  Amyotrophic lateral sclerosis
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05031  Amphetamine addiction
eai05152  Tuberculosis
eai05163  Human cytomegalovirus infection
eai05166  Human T-cell leukemia virus 1 infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05170  Human immunodeficiency virus 1 infection
eai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eai05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106842388 (PPP3CB)
   04310 Wnt signaling pathway
    106842388 (PPP3CB)
   04370 VEGF signaling pathway
    106842388 (PPP3CB)
   04020 Calcium signaling pathway
    106842388 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    106842388 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    106842388 (PPP3CB)
   04218 Cellular senescence
    106842388 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    106842388 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    106842388 (PPP3CB)
   04660 T cell receptor signaling pathway
    106842388 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    106842388 (PPP3CB)
   04659 Th17 cell differentiation
    106842388 (PPP3CB)
   04662 B cell receptor signaling pathway
    106842388 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    106842388 (PPP3CB)
   04921 Oxytocin signaling pathway
    106842388 (PPP3CB)
   04924 Renin secretion
    106842388 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    106842388 (PPP3CB)
   04728 Dopaminergic synapse
    106842388 (PPP3CB)
   04720 Long-term potentiation
    106842388 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    106842388 (PPP3CB)
   04380 Osteoclast differentiation
    106842388 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106842388 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106842388 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    106842388 (PPP3CB)
   05163 Human cytomegalovirus infection
    106842388 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106842388 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    106842388 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106842388 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    106842388 (PPP3CB)
   05020 Prion disease
    106842388 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    106842388 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    106842388 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106842388 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:eai01009]
    106842388 (PPP3CB)
Enzymes [BR:eai01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     106842388 (PPP3CB)
Protein phosphatases and associated proteins [BR:eai01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     106842388 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 106842388
NCBI-ProteinID: XP_014714360
UniProt: A0A8C4MGY8
LinkDB
Position
2:complement(107623223..107666188)
AA seq 525 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDVGSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSF
EEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHSAQ
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagcagtacctttccccccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacccagggttgatgttctgaagaaccacttagta
aaagaaggtcgagtagatgaagaaattgcgcttagaattatcaatgagggtgctgccatc
cttcggagagagaaaactatgatagaagtagaagctccaattacagtgtgtggtgacatc
catggccagttttttgatctgatgaaactttttgaagtaggcggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctatacccaagcacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaggaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcctgcctcttgctgcactttta
aaccaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcccaattttatggatgtcttcaca
tggtctttaccatttgttggagaaaaagtgacagaaatgttggtaaatgttctgagtatt
tgctctgatgatgaactaatgactgaaggtgaagaccaatttgatgtaggttcagctgca
gcccggaaagaaatcataagaaacaaaattcgagcaattggcaagatggcaagggtcttc
tctgttctcagggaggagagtgaaagtgtgctgacactcaagggcctgactcccacaggg
atgttgcctagtggagtgttggctggaggacggcagaccctgcaaagtgccacagttgag
gctattgaggctgaaaaagcaatacgaggattctctccaccacatagaatctgcagtttt
gaagaggcaaagggtttggataggatcaatgagagaatgccaccccggaaagatgctgta
cagcaagatggtttcaattctctgaacaccgcacatgccactgagaaccacgggactggc
aaccatagtgcccagtga

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