Equus asinus (ass): 106843817
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Entry
106843817 CDS
T04645
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
eai
Equus asinus (ass)
Pathway
eai00280
Valine, leucine and isoleucine degradation
eai00640
Propanoate metabolism
eai00785
Lipoic acid metabolism
eai01100
Metabolic pathways
eai01210
2-Oxocarboxylic acid metabolism
Module
eai_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
106843817 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
106843817 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
106843817 (BCKDHA)
Enzymes [BR:
eai01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
106843817 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
106843817
NCBI-ProteinID:
XP_014716519
UniProt:
A0A8C4LBR2
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Position
26:12248936..12266771
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AA seq
453 aa
AA seq
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MAVVTAAARVLGSSRGLGQDGLLLLRRLGVRGLAISHPQRQQQHFSSLDDKPQFPGASAE
FIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPNLPQEKVLKFYKSMTLLNTMDRILY
ESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCYG
NVSDLGKGRQMPVHYGCKERHFVTISSPLATQIPQGEDALPGPAVGAAYAAKRANANRVV
ICYFGEGAASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYG
IMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVN
YWDKQDHPISRLRHYLQSRGWWDDEQEKDWRKQSRKKVMEAFEQAERKPKPNFSLLFSDV
YQEMPAQLRKQQESLARHLQTYGEHYPLDHFEK
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggtgacagctgcggcgagagtcctgggatcaagtcgaggcctgggccaggat
ggcctactgctcttgcggcggcttggggttcgggggctggctatatctcacccccagagg
cagcagcagcacttctcgtccttggatgacaagccccagttcccaggggcctcagcggag
tttatagacaagctagagttcatccagcctaatgtcatctctgggatccccatctaccgc
gtcatggaccggcagggccagatcatcaaccccagcgaggaccccaatctgccccaggag
aaggtgctcaagttctacaagagcatgacactgctcaacaccatggaccgcatcctctac
gagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggaggggaca
cacgtggggagtgcagcagccctggacaacacggacctggtgtttggccagtaccgggag
gcaggtgtgctgatgtatcgggactaccccctggaactgttcatggcccagtgctacggc
aacgtgagtgacctgggcaaggggcgccagatgcccgtccactatggctgcaaggagcgc
cactttgtcaccatctcctctccactggccacgcagatccctcagggtgaggatgcactc
cctgggcctgcggtgggggcagcctacgcggccaagcgggccaatgccaacagggtcgtc
atctgttactttggtgagggggcggccagtgagggagatgcacatgccggcttcaacttc
gctgccaccctcgagtgccccatcatcttcttctgccggaacaacggctatgccatctcc
acacccacttctgagcagtaccgcggggatggcatcgcggctcgaggccccgggtatggc
atcatgtcaatccgcgtggacggcaatgatgtgtttgctgtgtacaacgccaccaaggag
gcccggcggcgtgccgtggcagagaaccagcccttcctcattgaggccatgacctacagg
atcgggcaccatagcaccagtgacgatagctcagcgtaccgctctgtggacgaggtcaat
tactgggacaagcaggaccaccccatctcgcggctgaggcactacctgcagagccgtggc
tggtgggatgatgagcaggagaaggactggaggaagcagtctcgtaagaaggtgatggag
gcctttgagcaggctgagcggaagccgaagcccaacttcagcctgctcttctcagatgtg
tatcaggagatgcccgcccagctccgcaagcagcaggagtccctggcccgtcacctccag
acctatggcgagcactaccccctggaccacttcgagaagtga
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