KEGG   Equus asinus (ass): 106844006
Entry
106844006         CDS       T04645                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
eai  Equus asinus (ass)
Pathway
eai03420  Nucleotide excision repair
eai04115  p53 signaling pathway
eai04120  Ubiquitin mediated proteolysis
eai05161  Hepatitis B
eai05169  Epstein-Barr virus infection
eai05200  Pathways in cancer
eai05202  Transcriptional misregulation in cancer
eai05210  Colorectal cancer
eai05212  Pancreatic cancer
eai05213  Endometrial cancer
eai05214  Glioma
eai05216  Thyroid cancer
eai05217  Basal cell carcinoma
eai05218  Melanoma
eai05220  Chronic myeloid leukemia
eai05222  Small cell lung cancer
eai05223  Non-small cell lung cancer
eai05224  Breast cancer
eai05225  Hepatocellular carcinoma
eai05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    106844006 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    106844006 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    106844006 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106844006 (DDB2)
   05202 Transcriptional misregulation in cancer
    106844006 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    106844006 (DDB2)
   05212 Pancreatic cancer
    106844006 (DDB2)
   05225 Hepatocellular carcinoma
    106844006 (DDB2)
   05226 Gastric cancer
    106844006 (DDB2)
   05214 Glioma
    106844006 (DDB2)
   05216 Thyroid cancer
    106844006 (DDB2)
   05220 Chronic myeloid leukemia
    106844006 (DDB2)
   05217 Basal cell carcinoma
    106844006 (DDB2)
   05218 Melanoma
    106844006 (DDB2)
   05213 Endometrial cancer
    106844006 (DDB2)
   05224 Breast cancer
    106844006 (DDB2)
   05222 Small cell lung cancer
    106844006 (DDB2)
   05223 Non-small cell lung cancer
    106844006 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    106844006 (DDB2)
   05169 Epstein-Barr virus infection
    106844006 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:eai04121]
    106844006 (DDB2)
   03400 DNA repair and recombination proteins [BR:eai03400]
    106844006 (DDB2)
Ubiquitin system [BR:eai04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     106844006 (DDB2)
DNA repair and recombination proteins [BR:eai03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      106844006 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_WDR75_1st Beta-prop_RIG_2nd WDR55 Beta-prop_WDR90_POC16_2nd Beta-prop_IFT140_1st Beta-prop_EIPR1 EIF3I Beta-prop_TEP1_2nd ANAPC4_WD40 Beta-prop_WDR19_1st Beta-prop_CAF1B_HIR1 WD40_RFWD3 Beta-prop_TEP1_C NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_HPS5 Beta-prop_Vps41 WD_LRWD1 Beta-prop_WDR11_1st
Other DBs
NCBI-GeneID: 106844006
NCBI-ProteinID: XP_014716800
UniProt: A0A8C4KZ62
LinkDB
Position
17:37162510..37191034
AA seq 427 aa
MAPRKRPETQKTPEMVVRPKSKRSRSPRELEPEAKKLCAKGPGSSRRLDSGCLWAELASL
QVPPLCSSIIRALHQQKLGKASWSSLQQGLQQSFLRSLASYRIFQKAAPFDRRATSLAWH
PAHPSTLAVGSKGGDIMLWNFGVKDKPTFLKGIGAGGSITGLKFNPLNTDQFFTSSMEGT
TRLQDFKGNTLRVFSSYDTCNFWFCSLDVSAKSRMVVTGDNVGHVILLNMDGKELWNLRM
HKKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLYSLPHRHPVNAACFSPDG
AQLLTTDQKSEIRVYSASQWDCPLNLIPHPHRHFQHLTPIKATWHPRYNLIVVGRYPDPN
FKSCTPYELRTIDVFDGSSGKMMHQLYDPESSGIISLNEFNPIGDTLASVMGYHILIWSQ
EEAGMRK
NT seq 1284 nt   +upstreamnt  +downstreamnt
atggctcccaggaaacgtccagaaacccagaagacccccgagatggttgtgcgccccaag
agcaagaggagcaggagccccagggagctggagcccgaggccaagaagctctgtgcgaag
ggccccggttccagcagaagacttgactcaggctgcctttgggcggagttggctagcctg
caggtcccgccactgtgcagcagcatcatcagggccctgcaccagcagaagctgggcaaa
gcttcctggtcatccctacagcagggtctccagcagtcctttttgcgctctctggcttct
taccggatattccaaaaggctgccccctttgacaggagggccacatccttggcgtggcac
ccagctcaccccagcaccctggctgtgggttccaaagggggagatatcatgctctggaac
tttggcgtaaaggacaaacccaccttccttaaagggattggagctggagggagcatcact
gggctgaagtttaaccctctcaataccgaccagtttttcacctcctcaatggagggaaca
actaggctgcaagactttaaaggcaacactctccgagttttttccagctatgacacctgc
aacttctggttttgcagcctggatgtgtctgccaaaagccgaatggtggtcacaggagac
aacgtgggccatgtcatcctgctgaacatggacggcaaggagctttggaatctgagaatg
cacaaaaagaaagtgacccatgtggccctgaacccgtgctgtgactggttcctggccaca
gcctccgtagatcaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagc
ttcctctactcgctgccgcacaggcatcctgtcaacgcagcttgtttcagtcccgatgga
gcccagctcctgaccactgaccagaagagtgagatccgggtttactctgcctcccagtgg
gactgccccctgaacctgatcccacaccctcaccgccacttccagcacctgacgcccatc
aaggcaacctggcatcctcggtacaacctcattgtcgtgggccgatacccagatcctaat
ttcaaaagttgtaccccctatgaattaaggacgatcgatgtgtttgatggaagctcaggg
aagatgatgcatcagctctatgacccagaatcttctggtatcatttcgctcaatgagttc
aatcccattggggacacgctggcctctgtgatgggttatcacattctcatttggagccag
gaggaagctgggatgcggaagtga

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