KEGG   Equus asinus (ass): 106844288
Entry
106844288         CDS       T04645                                 
Symbol
CACNA1A
Name
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent P/Q-type calcium channel subunit alpha-1A
  KO
K04344  voltage-dependent calcium channel P/Q type alpha-1A
Organism
eai  Equus asinus (ass)
Pathway
eai04010  MAPK signaling pathway
eai04020  Calcium signaling pathway
eai04721  Synaptic vesicle cycle
eai04723  Retrograde endocannabinoid signaling
eai04724  Glutamatergic synapse
eai04725  Cholinergic synapse
eai04726  Serotonergic synapse
eai04727  GABAergic synapse
eai04728  Dopaminergic synapse
eai04730  Long-term depression
eai04742  Taste transduction
eai04930  Type II diabetes mellitus
eai05017  Spinocerebellar ataxia
eai05032  Morphine addiction
eai05033  Nicotine addiction
eai05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106844288 (CACNA1A)
   04020 Calcium signaling pathway
    106844288 (CACNA1A)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    106844288 (CACNA1A)
   04727 GABAergic synapse
    106844288 (CACNA1A)
   04725 Cholinergic synapse
    106844288 (CACNA1A)
   04728 Dopaminergic synapse
    106844288 (CACNA1A)
   04726 Serotonergic synapse
    106844288 (CACNA1A)
   04730 Long-term depression
    106844288 (CACNA1A)
   04723 Retrograde endocannabinoid signaling
    106844288 (CACNA1A)
   04721 Synaptic vesicle cycle
    106844288 (CACNA1A)
  09157 Sensory system
   04742 Taste transduction
    106844288 (CACNA1A)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    106844288 (CACNA1A)
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    106844288 (CACNA1A)
  09165 Substance dependence
   05032 Morphine addiction
    106844288 (CACNA1A)
   05033 Nicotine addiction
    106844288 (CACNA1A)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    106844288 (CACNA1A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:eai04040]
    106844288 (CACNA1A)
Ion channels [BR:eai04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   106844288 (CACNA1A)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 106844288
NCBI-ProteinID: XP_044607833
LinkDB
Position
20:11309851..11506138
AA seq 2479 aa
MARFGDEMPARYGGGGSGAAAGVVVGAGGGRGAGGSRQGGQPGAQRMYKQSMAQRARTMA
LYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQH
LPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTG
ILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIF
AIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQ
FDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGVLS
GEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDVEQRLPFDAL
RRATIKKSKTDLLHPEEAEDQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRFYIR
RMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGL
GTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWASLR
NLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAIMTV
FQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQ
ELTKDEQEEEEAANQKLALQKAKEVAEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSE
MRKQNLLASREALYSEMDPDERWKAAYARHLRPDMKTHLDRPLVVDPQENRNNNTNKSRA
AEPAGESRARAPSRADDLLRKPRPHERARDAGVPGSPDARRAWTGGPEPEPEPSRQGPYG
RESDPRAREGGPEPPAAWEGEXERGGPGDAPRRRAPRPGGSRDGRGGSPRTGADGEPXRH
RAHRRADEGAEDKAERRARHREGXPSPGGEADGEGPEGGERRRRHRHGPAAHNADARRED
RERRHRRRRENQGPGVPVPGPNLSTTRPIQQDLGRPDPPLAEDIDNMKNNKLATAEAAGP
HASLGPAGPPPSPAKMGNSTEPGVAAATPQNTASRRAPNNPGTPCNPGPPRTPENSLIVT
NPSSTQSNSAKTARRPDHTAVDIPPACPPPLSHTVVQVNKNANPDPLPKKEEEKKEEEDD
PGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQP
NAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFA
FTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMF
IFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWA
LLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVAL
IIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMPQNKQSFQYRMWQFVVSPPFE
YTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLFSLECLLKVMAFGILNYFRDA
WNIFDFVTVLGSITDILVTEFGNPNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQ
SFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDDFQITEHNNFRTFFQALM
LLFRSATGEAWHNIMLSCLSGKPCDKNSGILTPECGNEFAYFYFVSFIFLCSFLMLNLFV
AVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMPYPDMYQMLRHMSPPLGLGK
KCPARVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEM
MAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAMREEQNRTPLM
FQRMEPPSPTQEGGPSQNALPSTQLDPGGGLMAHDSGLKESPSWVTQRAQEMFQKTGTWS
PERGPPADMPHSQPDSQSVEMREMGRDGYSDSEHYLPMEGQARAASMPRLPAENQRRRGR
PRGNNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEENQRHHQRRRDRGHRASERS
LGRYTDVDTGLGTDLSMTTQSGDLPPKERDQERGRPKDRKHRQHHHHHHHHHPPPADKER
FAPERPEHGRPRARDQRWSRSPSEGREHMAHRQGSSSVSGSPAPSTSGTSTPRRGRRQLP
QTPSTPRPHVSYSPVVRPAGGAGPPQQKQQQPPAARPARAVPGXARRYPGPAAEPAPGER
PPAGGHGSSRSPATERXGPGRSQSPRACRHGGARWPAAEGPPGARLHGYYRGSDYDEAEG
PGGGGDEPRAGPYDAPPPRRSSSPRTPRXRGPRGASPARHGRRLPNGYYPAPGAARPRGP
GARKGLREAYSETDDDDWC
NT seq 7440 nt   +upstreamnt  +downstreamnt
atggcccgcttcggagacgagatgccggcccgctacgggggaggaggctccggggcggcc
gccggggtggtcgtgggcgccggcggcgggcgaggagccgggggcagccggcagggcgga
cagcccggggcgcaaaggatgtacaagcagtcgatggcgcagagagcgcggaccatggcc
ctctacaaccccatccccgtccgacagaactgcctcacggtcaaccgctccctgttcctc
ttcagcgaggacaacgtggtgagaaaatacgccaaaaagatcaccgaatggcctcccttt
gaatacatgattttagccaccatcatagccaactgcatcgtcctcgccttggagcagcac
ctgcccgatgacgacaagaccccgatgtctgaacggctggatgacacagaaccatacttc
attggaattttctgcttcgaggctggaattaagatcatcgcccttgggttcgccttccac
aaaggctcttacttgaggaacggctggaacgtgatggactttgtggtcgtgctaacgggc
atcttggcgacagtcgggacggagttcgacctgcggacgctgagggcagttcgggtgctg
cggccgctcaagttggtgtctgggatcccaagtttacaagtcgtcctgaagtcgatcatg
aaggcaatgatccccctgctgcagatcggtctcctgctgtttttcgcgatccttattttt
gcaatcatagggttagaattttatatggggaaattccacaccacctgctttgaggagggt
acagacgacattcagggtgagtccccggctccgtgtgggacagaggaacccgcccgcacc
tgccccaatgggaccaaatgtcagccctactgggaagggcccaacaacgggatcactcag
ttcgacaacatcctgttcgcagtgctgactgtgttccagtgcatcaccatggagggctgg
accgacctcctctacaacagcaacgacgcctcagggaacacttggaactggttgtacttc
atccccctcatcatcatcggctccttttttatgctgaacctcgtgctgggcgtgctgtca
ggggagttcgccaaggagcgcgaacgggtggagaaccggcgggccttcctgaagctgagg
cgccagcagcagatcgagcgggagctcaacggctatatggagtggatctcaaaagcagaa
gaggtgatcctcgccgaggatgagaccgacgtggagcagaggctgccttttgatgctctg
cggagggccaccatcaagaagagcaagacggacctgctccaccccgaggaggcggaggac
cagctggccgacattgcctctgtggggtctcccttcgcccgggccagcatcaaaagtgcc
aagctggagaactcgaccttttttcacaaaaaggagaggaggatgcgtttctacatccgc
cgcatggtcaaaactcaggccttctactggactgtgctcagcctggtggccctcaacacg
ctgtgcgttgccatcgtccactacaaccagcccgagtggctttccgacttcctctactat
gcagaattcattttcttaggactctttatgtccgaaatgtttataaaaatgtacggactc
gggacgcggccttacttccactcttcgttcaactgctttgactgtggggtcatcatcggc
agcatcttcgaggtcatctgggccgtcataaagcccggcacgtccttcggaatcagcgtg
ttacgagccctcaggttactgcgcattttcaaagtcacaaagtactgggcatccctcagg
aacctggttgtctcgctcctcaactccatgaaatccatcatcagcctcctgttcctcctc
tttctcttcatcgtcgtctttgcccttttgggaatgcagctcttcggcggccagttcaac
tttgacgaagggacgcctcctaccaacttcgacactttcccagcagcaataatgacggtg
tttcagatcctgacgggtgaagactggaacgaggtcatgtacgatggcatcaagtcccag
ggcggcgtgcagggcggcatggtgttctccatctacttcattgtgctcacgctcttcggg
aactacaccctcctgaacgtgttcttggccatcgcggtggacaacctagccaacgcccag
gagctgaccaaggacgagcaagaggaggaggaggccgccaaccagaaacttgcactccag
aaggccaaggaggtggccgaagtgagccctctgtccgcggccaacatgtccattgccgtg
aaggagcagcagaagaaccagaagcccgccaagtcggtgtgggagcagcggacgagcgag
atgaggaagcagaacctgctggccagccgagaggccctgtacagcgagatggacccggac
gagcgctggaaggcggcctacgcgcggcacctgcggccggacatgaagacgcacctggac
cggccgctggtggtggacccgcaggagaaccgcaacaacaacaccaacaagagccgggcg
gccgagccggcgggggagagccgcgcccgggcccccagccgcgccgacgacctcctgcgc
aagccgcggccgcacgagcgcgcgcgggacgccggcgtccccgggtccccggacgcgcgc
cgggcctggacgggcggccccgagcccgagcccgagcccagccgccaggggccctacggc
cgcgagtcggacccgcgcgcgcgcgagggcggcccggagccgccggcggcctgggaggga
gaangcgagcgcggcgggcccggggacgccccccgccgccgtgcgccccggccaggcggc
agccgcgacggccgcggggggtccccgcgcaccggcgccgacggcgagcccngcaggcac
cgcgcgcaccggcgcgccgacgagggcgcggaggacaaggcggagcgcagggcccggcac
cgcgagggcnagcccagcccgggcggcgaggcggacggcgagggccccgagggcggcgag
cgcaggcggcggcaccggcacggccccgcggcccacaacgcggacgcgcgcagggaggac
cgggagcgccggcaccggcggcgcagagagaaccagggcccgggagtcccggtgccgggc
cccaacctgtcgaccacccggcccatccagcaggacctgggccgcccggatccgccgctg
gccgaggacatcgacaacatgaagaacaacaagctggccaccgccgaggcggccggtccc
cacgccagcctgggccccgccgggccgcccccgagccccgccaagatggggaacagcacg
gagcccggcgtcgcagccgccaccccgcagaacaccgccagccgccgggcgcccaacaac
ccggggacgccgtgcaaccccggcccccccaggacccccgagaacagccttatcgtcacc
aaccccagcagcacccagagcaactcagccaagactgccaggaggcccgaccacacggcc
gtggacatcccgcccgcctgcccgccgcccctcagccacaccgtcgtgcaagtgaacaaa
aacgccaacccagacccactgccaaaaaaggaggaggagaagaaggaggaggaggacgac
cctggggaggacggcccgaagcccatgcccccctacagctccatgttcatcctctccacc
accaacccccttcgccgcctgtgccattacatcctgaatttgcgctacttcgagatgtgc
attctcatggtcatcgccatgagcagcattgccctggcggctgaggaccccgtgcagccc
aacgccccccggaacaacgtgctgcgatattttgactatgtttttacgggcgtcttcacc
tttgagatggtgatcaagatgatcgacctggggctcgtcctgcaccagggcgcctacttc
cgtgacctctggaacatcctcgacttcatcgtggtcagtggggcgctggtggccttcgcc
ttcaccggcaacagcaaaggaaaggacatcaacaccatcaagtccctccgagtcctccgg
gtgctacgacctctgaaaaccatcaagcggttgccaaagctcaaggccgtgttcgactgc
gtggtgaactcgctcaagaacgtgttcaacatcctcatcgtctacatgctgttcatgttc
atcttcgcggtggtggccgtgcagctgttcaagggcaagttcttccactgcaccgacgag
tccaaagaattcgagaaggactgtcgcggcaagtacctgctgtacgagaagaacgaggtg
aaggcgcgcgaccgcgagtggaagaagtacgagttccactacgacaacgtgctctgggcc
ctgctgacgctcttcaccgtgtccaccggcgagggctggccgcaggtcctcaagcactcg
gtggacgccacgttcgagaaccagggccccagccctgggtaccgcatggagatgtccatc
ttctacgtcgtctactttgtggtcttccccttcttctttgtcaacatcttcgtggccttg
atcatcatcacgttccaggagcagggcgacaagatgatggaggagtacagcctggagaag
aacgagagggcctgcatcgacttcgccatcagcgccaagccgctgacgcgccacatgccg
cagaacaagcagagcttccagtaccgcatgtggcagtttgtggtgtcgccgccgttcgag
tacaccatcatggccatgatcgccctcaacaccatcgtgctcatgatgaagttctacggg
gcctcggtggcgtacgagaacgccctgagagtgttcaacattgtcttcacctcgctcttc
tccctcgagtgcctgctgaaggtcatggcttttggcattctgaattacttccgtgatgcc
tggaacatcttcgattttgtgactgttctgggcagcatcaccgacatcctcgtgacggag
tttgggaatccgaacaacttcatcaacctgagcttcctccgcctgttccgtgctgcccgg
ctcatcaaactcctccggcagggctacaccatccgcatccttctctggaccttcgtgcag
tccttcaaggcgctgccatacgtctgtctgctgatcgctatgctcttcttcatctacgcc
atcatcgggatgcaggtgttcggcaacatcggcatcgacgtggaggacgaggacagtgat
gaggatgacttccaaatcaccgagcacaacaacttccggaccttcttccaggcgctcatg
ctgctcttccggagtgccaccggggaggcttggcacaacatcatgctttcctgcctcagt
gggaagccgtgtgataagaactctggcatcctgactcctgagtgtggcaatgaatttgcc
tatttttacttcgtttccttcatcttcctctgctcgtttctgatgctgaacctctttgtt
gctgtcatcatggacaactttgagtacctcactcgagactcctccatcctgggtccccac
cacctggatgagtacgtgcgtgtctgggcggagtacgaccccgcagcgtggggccgcatg
ccttacccggacatgtatcagatgctgagacacatgtctccgcccctgggtctggggaag
aagtgtccggccagagtggcttacaagaggctcctgcggatggatctacctgtcgctgat
gacaacactgtccacttcaattctaccctcatggctctgatccgcacggccctggatatc
aagatcgccaagggcggagccgacaaacagcagatggacgctgagctgcggaaggagatg
atggccatctggcccaacctgtcccagaagacgctggacctgctggtcaccccgcacaag
tccacagacctgacggtggggaagatctacgcggccatgatgattatggaatactaccgg
cagagcaaggccaagaagctgcaggccatgcgcgaggagcagaaccggacaccgctcatg
ttccagcgcatggagccgccgtccccgacgcaggagggggggcccagccagaatgccctc
ccctccacccagctggacccaggaggaggcctgatggctcacgacagtggcctcaaggag
agcccgtcctgggtgacccagcgagcccaggagatgttccagaagacgggcacctggagc
ccggagcgggggccccccgccgacatgccccacagccagcccgactcccagtctgtggag
atgcgagagatgggcagagacggctactcggacagcgagcactacctccccatggaaggc
caggcccgggccgcctccatgccccgcctccccgccgagaaccagaggagaaggggccgg
ccacgtgggaataacctcagtaccatctcagacaccagccccatgaagcgctcggcctcc
gtgctgggccccaaggcccggcgcctggacgactactccctggagagggtgccgcccgag
gagaaccagcggcaccaccagcggcggcgcgaccgcggccaccgcgcctccgagcgctcc
ctgggccgctacacggacgtggacacaggcttggggacggacctcagcatgaccacgcag
tcgggggacctcccgcccaaggagcgggaccaggagaggggccggcccaaggaccggaag
caccggcagcaccaccaccaccaccaccaccaccacccgccgcccgccgacaaggagcgc
ttcgccccggagcggcccgagcacggccggccgcgcgcccgggaccagcgctggtcgcgc
tcgcccagcgagggccgagagcacatggcgcaccggcagggcagtagttccgtaagtgga
agcccagccccctcaacatctggtaccagcactccgcggcggggccgccgccagctcccc
cagaccccctccaccccccggccgcacgtgtcctactcccccgtggtccggccggccggc
ggcgcgggccccccgcagcagaagcagcagcagcccccggcggcgcggccggcccgggcg
gtccccggcngcgcgcggaggtacccggggcccgcggccgagcccgcgcccggggagcgg
ccgcccgcggggggccacggcagcagccgctcgcccgcgacggagcggncgggtccgggc
cggagccagtccccccgcgcgtgtcgccacgggggcgcgcgctggccggcggccgagggg
cccccgggcgcccggctccacggctactaccggggctccgactacgacgaggccgagggc
ccgggcggcggcggggacgagccccgggccgggccctacgacgccccccccccgcgccgc
tccagctcgcccaggactccccggnnccgcgggccccgcggcgcctccccggcgcggcac
ggccggcgcctcccgaacggctactacccggcgcccggcgccgcccggccccgcggcccc
ggcgcccgcaaaggcctgcgcgaagcctacagcgagaccgacgacgacgactggtgctag

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