KEGG   Equus asinus (ass): 106845267
Entry
106845267         CDS       T04645                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
eai  Equus asinus (ass)
Pathway
eai04120  Ubiquitin mediated proteolysis
eai04380  Osteoclast differentiation
eai04630  JAK-STAT signaling pathway
eai04668  TNF signaling pathway
eai04910  Insulin signaling pathway
eai04917  Prolactin signaling pathway
eai04920  Adipocytokine signaling pathway
eai04930  Type II diabetes mellitus
eai04931  Insulin resistance
eai04932  Non-alcoholic fatty liver disease
eai04935  Growth hormone synthesis, secretion and action
eai05160  Hepatitis C
eai05164  Influenza A
eai05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:eai00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    106845267 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    106845267 (SOCS3)
   04668 TNF signaling pathway
    106845267 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    106845267 (SOCS3)
   04920 Adipocytokine signaling pathway
    106845267 (SOCS3)
   04917 Prolactin signaling pathway
    106845267 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    106845267 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106845267 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    106845267 (SOCS3)
   05164 Influenza A
    106845267 (SOCS3)
   05168 Herpes simplex virus 1 infection
    106845267 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    106845267 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    106845267 (SOCS3)
   04931 Insulin resistance
    106845267 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:eai04121]
    106845267 (SOCS3)
Ubiquitin system [BR:eai04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     106845267 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 106845267
NCBI-ProteinID: XP_014718725
UniProt: A0A9L0J5A7
LinkDB
Position
13:complement(60534544..60537778)
AA seq 229 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPSLPSPPTEPSSSPSSEVPDQPPAQPLPGNPPRRAYYIYSGGEKIPL
VLSRPLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 690 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagctccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgaccggcggcgaggcgaacctgctgctc
agcgctgagccggccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaagggggc
agtttctcgctgcagagcgacccccggagcacgcaaccggtgccccgcttcgactgcgtg
ctcaagctggtgcatcactacatgccgccccccggcgccccctccctcccctcgccaccg
actgaaccctcctcctcgccctcctccgaggtgccagatcagccgccggcccagccgctc
ccggggaacccccccaggagagcctattacatctactcggggggcgagaagatccctctg
gtcttgagccggcccctctcctccaacgtggccactctccaacatctctgtcggaagacc
gtcaacggccacctggactcctatgagaaagtcacccagctgcctgggcccattcgggag
ttcctggaccagtacgatgccccgctttaa

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