Equus asinus (ass): 106845376
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Entry
106845376 CDS
T04645
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
eai
Equus asinus (ass)
Pathway
eai05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
106845376 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
eai03021
]
106845376 (SETX)
Enzymes [BR:
eai01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
106845376 (SETX)
5.6.2.5 RNA 5'-3' helicase
106845376 (SETX)
Transcription machinery [BR:
eai03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
106845376 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
AAA_16
Helicase_RecD
TniB
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
106845376
NCBI-ProteinID:
XP_044634433
UniProt:
A0A8C4LRJ9
LinkDB
All DBs
Position
10:11896597..11973058
Genome browser
AA seq
2678 aa
AA seq
DB search
MSTCCWCTPGGISTIDFLKRYASRTHSREFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERPSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTKIEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLSSLLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQADAVCDKVSEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTSAFARSSEKSSGNCSKGTSMMSSLSLHSLPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKVKPP
PCNTLVDLTPACKTPPASYTKEENEQIGKKSKKDIRCLENSSPTFSKEPMKADAYQVQES
LLIKASNTVEDNEQNYIKDIKLEDHLSTESCLKQSSKNLVTERAQDEVKISTRKQKSVKE
NSLHKRQNCTSRNGPEKGCDRGIIISTRLLTDSSTDFLEKVSTSNEDFPLKDDAVSKTSK
AKSQKDEICAKLSHVIKKQHRKSTLVDNAVNLEENQTVSNVENLFSRKDIGGQKGDSFVH
NLSLDPNGILDDKNGEQKSQSSLLLKKKQLKNEELDIFSSHEKSCQIQECHADDKDLVSF
TEMTNTFMKKTSPFKDPMTVIESREKEISKSTDQVSSNLREQAPSISPNSDTLTDSQIDR
DLHKLSLIAQASVIKFPSDSAQRNSSQLQRKVRDDKRCFTANQNKVGETCHEQVIIISDS
DDDDDGDERILRFEKHTNKQDKICVEKECPEQHIAVDNTNVEKKLIKEEETQSLLQFEES
DSQFFEFESPCEVFSVWQDQKPDNKNSVQEDEKNSCLTHIVDITNDWGYDTDYVSEEVIK
KVSEGIEEHAEPQSTSISVEEFCEIEVKKPKRKQIEKPMAEDPLRPSSTSKEVQPDILND
KGLTENNFKSIDIKTTTPNSSIQRATTISLKKSSPKPHAYSKPVRKVPLSKTPKKTHSDA
KKGQNKNSNYISCRTAPAVVPPKKFRQCPEPTSKVEKLGLKKAPRRAFELSQRSLEHIGK
LRDHGKTVGVVDTPKKTKLISQTSVKNNKKLLKNQDLQLQRQMRSRSQQNKQRCFDYEST
DTMKTRSRTAQNSDIFVPGSARSDNKGGTEVIADSDGRQLIKCASSELEPVKTKYVSQVT
DTCLLNQCNSVVLNGRIPTNEIIVSTSEEPLGGSDLTAHHLELAILKEQEPESNSDIEED
NIFLTQRDPEDMDLCSQMENGNDKLIEVVHGKDTVQVEDDSVRQPQLESLSSAKCKYKDC
VETMKNEGEYCLKHSEVKAADEDVFRKPSLPLSSSKPWRPTTKIFSSRSTSRIAHLSKSL
ENTSALPPALKNKSNGVQSILKAPQPASLVSQKPMGEVKSLCNVLHSQTPNNSNRQGYKL
PFGENKSFLASSPVSILLSSQSVSDTFVKEVLKWKYEMFVNFDQCGPPASLCQSISRPVP
VKFQDCGEYFNVFLPLMILNTFETVAQEWISSPNKEKFCQLHLRKFPADYKKYWEFVVYL
EECELAKQLHPKENDLVFLVPERLNGEKKAIERNCMQDPHEYHCGYVHKFRRTSVMRNGK
SEYSLSIQTQDNLPVNLNELVKCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDF
CTKDLLTTTSDRIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIV
GLLYRLLTENHRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNP
LGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQDMHRRKEYLDHQLDEL
SRQRALCRGGREVQRQELDEKIASVSKERQELASKIKEVQGRPQKTQNNIILESHVICCT
LSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPT
VISMKAQDYGYDQSMMARFYKLLEENVEHNVISRLPILQLTVQYRMHPDICLFPSNYVYN
KSLKTNRLTETSRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDKR
RDVTFRNIGIITHYKAQKTMIQKDLDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRANA
TQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMDNEHWNELIQDAQKRGAIIKTCDKN
YKHDAMKILKLKPVLQRSLTHPSAVAPEVSRPQGGLPSNKLDSEFAKTSFASSLYHTPSD
SKETTVTAKDPERPSGQDWLRDPRLLRRMGMSPEAKGKCLMDPQSLSPQHPGATPPSGEP
GFPVIHQDVGSVQQSAAKGATLSNHKPHVQCDPPAASGDAATSRRKCDQEGMLSYRRETR
AFSEGDQEKYSSVSHHTKRNSGWDKEEEDSSSKKRKVL
NT seq
8037 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcctggtggtatttccaccattgacttcctaaagcgc
tatgcatccaggacccactccagggaatttcaaacagctgatgaagacctctgttactgc
ttagagtgtgtggccgaataccataaagcaagggatgaattgccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaatcactttgaaaaatccatgaaagcagaa
attggagatgatgatgaattgtatatagtagacaacaatggagaggcacaactgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaagcatccagggatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaggaggttttgacttgcctttttaaagtcatt
gaattggggcttttagaaagtccggacatttatacttcttctgtccttgaaaagggcaaa
ctgattcttctgccctcgcacatgtatgatactaccaactataaaaactattggttaggt
atttgcatgttgctgaccattcttgaggagcaagccatggattcactgttgttgggctca
gacaaacaaaatgactttatgcaatcaatacttcacaccatggagaggccatcagatgat
gatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacttattgatcctattgaagcatttcaaactattatcaat
aatgtgagctacaatagagagattcaaaatatacggaacagctctgtaaggaccaagata
gaaccggagtcatatttggatgacatggtgacttgcagccagattgtatacaattataat
cctgaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattatccagtttgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctgtggttcatcccttttgttcaatccctcatggat
cttaaggatttgggtgtggcttatatagtagaggttattcatcatctgcattctgaagtc
aaagatgtcctcaaccaagcagatgctgtgtgtgacaaagtcagtgaattttttcttcta
attttggtgtcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggtt
agttcccagcaatgggttgaagccgttgtaaaatgtgccaaacttccaaccagtgcattt
gcacggagttctgagaaatcatctggaaattgctccaaaggaacatcaatgatgtcatct
ctgtcattgcattcactgccatctaactctgtacaacttgcgtgtgtgcaactgattaga
agtctccttaaagaaggttatcagcttgggcagcaaactctttgtaagcgattctgggat
aagctcaatttattcctgcgaggaaatctatctctaggttggcagctgactagtcaggaa
acccatgagttacaaacttgtttaaagcaaattattcgaaacataaaagtcaaaccacct
ccttgtaacactttggtggatctgactcctgcgtgtaaaacccctcctgcatcttatact
aaagaggaaaatgaacaaataggaaagaagtctaaaaaagacatacgctgtctggaaaat
tccagcccaacgttttctaaagaaccaatgaaagctgatgcatatcaagtgcaggagagt
ctattgattaaagcaagtaacactgtagaggataatgagcaaaattatataaaagacatc
aaactagaagaccatctttcaactgagtcatgtttaaagcagagtagtaaaaatcttgtc
actgaaagagctcaagatgaagttaaaataagtacaaggaagcagaagtctgtgaaagag
aattccttacataaacgacagaattgtacttcaagaaatggtccagaaaaagggtgtgac
agaggaataataatatcaacacgtttgttgactgattctagcactgattttctggaaaag
gtgtccacatcaaatgaagatttccctttaaaggatgatgctgtcagtaaaacctcaaaa
gctaagtcacagaaagatgaaatctgtgctaagttatcacatgtgataaagaagcaacac
aggaaaagtactttggtcgataatgctgtcaatttagaggaaaaccagactgtatctaac
gttgagaatttgttttcaaggaaagatataggaggtcagaaaggggatagctttgtacac
aatctctctttagaccctaatggtattctggatgataaaaatggagagcaaaaatctcaa
agcagtttattactgaaaaagaaacaattaaagaatgaagagttagatattttctcttcc
catgaaaagagttgtcaaatacaagaatgtcatgctgatgataaagatttggtctcgttt
acagaaatgactaatactttcatgaagaaaacatctccctttaaagatcccatgactgta
attgaatcaagagagaaggaaattagcaagagtaccgatcaggtttcttctaatttgaga
gaacaggcccctagcatcagtcctaattctgacactttaacagattctcagatagaccga
gacctccacaaattgtctttaatagctcaggctagcgttattaagtttccatcagattca
gcacaaagaaactcatcccagctacaaagaaaagtaagagatgataagagatgtttcaca
gctaaccaaaacaaagttggagaaacctgccatgaacaggtgattattatttcagattct
gatgatgatgatgatggtgatgaaagaattctgcgttttgagaaacacactaataaacaa
gataaaatatgtgttgagaaagaatgtccagagcagcatattgcagtagataatacaaat
gtggaaaagaagctaataaaagaagaagagacacagtcccttttacagtttgaggaatct
gattctcagttttttgagtttgaaagtccatgtgaagtgttttcagtttggcaagatcag
aaaccagacaacaagaattcagttcaagaggatgaaaaaaattcatgcttgactcatata
gttgatatcacaaatgattggggttatgatacagattatgtatctgaagaggttattaaa
aaagtatcagagggcattgaagaacacgcagaaccacagagtactagtatttctgttgag
gaattttgtgaaattgaagtaaaaaaacctaagagaaaacaaattgaaaaacctatggct
gaagaccctttaaggccttcatctaccagcaaggaggtccagcctgatattcttaatgat
aaaggtctgactgaaaataattttaaaagtattgacataaagactacaactcccaattca
agtattcagagagccaccactatttccctaaagaaatcttctccgaagcctcatgcttat
tccaaacccgttaggaaagtcccactttctaaaacccctaagaaaacacattcagatgcc
aaaaaaggacagaataaaaattcaaattacataagttgtaggacagctcctgctgtagtg
ccaccaaagaaatttcgccagtgtcctgaaccaacttcaaaagttgagaaacttggtctg
aaaaaggctcctcgtagggcatttgagttgtctcagcggtctttagagcatataggtaag
ttacgtgaccatggcaaaactgttggagtagttgataccccaaagaagactaaattaatt
tctcagacttctgtcaaaaataataagaaattgctgaaaaatcaagatctgcagttgcaa
aggcagatgagatccagatcacaacaaaataaacaaagatgttttgattatgaaagtaca
gatactatgaaaacaaggtcacgcacagcgcagaattctgacatatttgtaccaggatca
gctaggtcagataataaaggaggaactgaggtaattgctgacagtgatggcaggcaatta
ataaaatgtgcatcttctgaactagaacctgtgaaaacaaaatatgtttcccaggtgact
gatacttgtcttttgaaccagtgtaattctgtagtgttaaatggaagaataccaacaaat
gaaataattgtttctacttcagaagaacctttaggtggaagtgacctaacagcacatcat
ttagagctggcaattttgaaagagcaagagcctgaatccaacagtgatatagaggaagat
aatatatttttaacacaacgtgaccctgaggatatggatttatgttcacaaatggagaat
ggtaatgataaactcattgaggtagttcatggaaaagatactgttcaggtagaagatgat
tccgtaagacagcctcagttggaatctttgagtagcgcaaagtgtaagtacaaagattgt
gttgaaactatgaaaaacgagggtgagtactgcttgaaacactctgaagttaaagcagca
gatgaagatgtatttcgtaaacctagcttgcctctttcttcatctaaaccttggagacct
accactaagatttttagctcacgtagtacttcacgaattgctcatctttccaagtctttg
gaaaatacctcagcacttccaccagctctgaaaaataagtcaaatggggtacaatctatt
ttgaaagcaccacagccagcctctctcgtgtctcagaagccaatgggtgaagtgaagagt
ttgtgcaatgttcttcattctcagactccaaataattccaacagacaaggttacaaactt
ccatttggtgaaaacaagtcttttttggcttcctctccagtaagcattctcttgtcatca
cagtctgtctctgacacctttgttaaagaggtcttaaaatggaaatatgaaatgtttgtg
aactttgatcagtgtgggcccccagcaagtctttgtcagtccatctcaagacctgtgcct
gtcaaatttcaagattgtggagaatatttcaacgtttttcttcctttgatgatactgaat
acttttgaaacagtggcacaggaatggatcagctctccaaataaagagaaattctgtcag
ttacatttacgaaaatttcctgctgattataaaaaatactgggagtttgtggtttatctt
gaagaatgtgaactagctaaacaacttcatccaaaggaaaatgatttggtgtttttggtt
cctgaaagactaaatggagagaagaaagctatagagagaaattgcatgcaagaccctcat
gaatatcattgtggttatgttcataaatttcgccgcacttcagtcatgcgtaatgggaaa
tctgagtattccctttccatccagactcaagataatttgccagtcaatttaaatgaactc
gtgaaatgtattgtaatcagttctctggtaactacacaaaggaagttgaaagccatgtct
ttgctgagtggtcggaaccaactggccagagctgttctgaatccaaaccccatggacttc
tgtacaaaagatttacttactacaacatctgacagaattattgcctacctaagagatttc
aatgaagaccaaaagaaagcgatagaaactgcatatgccatggtgaaacactccccatca
gttgccaagatatgtctcattcatggaccacctggaacaggaaaatcaaaaactattgtt
ggcctcctctatcgcctactgaccgagaaccataggaaggggcattcagatgaaaactcc
aatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcaccttccaatgcagctgttgat
gaacttatgaaaaaaattatcctcgaattcaaggaaaaatgtaaagacaagaagaatcct
ttgggaaactgtggagatataaatttagtacgtctgggtccagagaagtctattaataat
gaggtcctaaaattcagtttggacagccaagttaaccacagaatgaaaaaagacttacct
tctcatgttcaggacatgcatagaagaaaggaatatctggatcatcaactagatgaactt
tcccgccagcgtgctttatgccgaggtggaagggaagtacagaggcaagaattagatgaa
aaaattgccagcgtttcaaaagaaaggcaggaacttgcttcgaaaattaaagaggttcaa
ggacgcccacaaaaaacacagaataatatcatcttagagtcccatgtcatctgctgcaca
ttgagcaccagtggtggtttactgcttgagtctgcttttcgtgggcaaggaggtgtcccc
tttagttgtgtcattgtcgatgaggctgggcagtcttgtgaagttgaaacgcttactcca
cttatccatcgttgtaacaagcttatccttgtaggagatcctaaacagctccctcccaca
gtcatttctatgaaggcacaggattatggctatgaccagtcgatgatggctcgcttctac
aaactgctggaagagaatgtagagcacaacgtgatcagcagactcccgattttacagctc
accgttcagtacaggatgcacccagacatatgtctcttcccttctaactatgtgtataac
aaaagcttgaaaacaaatagactaactgagaccagtcggtgttcgtcagactggccattt
caaccctaccttgtgtttgatgtcggagatggttcagaaagacgggataatgactcatat
gtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaagacaaaaga
agagatgttactttccgaaacattggcataataacccattacaaagctcagaagacgatg
attcaaaaagatttggacaaagagtttgacggaaaagggccagcagaagtagataccgtg
gatgccttccaggggcgtcagaaagattgtgtcattgttacctgtgtcagagcaaatgcc
acacaaggctcaattggatttctggcaagtttgcagagattgaatgtcaccattacacga
gccaagtacagcctcttcatccttggtcatttgaggaccctcatggacaatgagcattgg
aacgaactgattcaggatgctcagaagcgtggtgccattattaagacctgtgacaaaaac
tataaacatgatgcaatgaagattctgaaactcaagcctgtactacagagaagtctgact
cacccttcagctgtagccccagaggtgtccagaccccagggcggcttgcccagcaacaag
ctagacagtgaatttgccaagacatcttttgcttcttccctgtaccacaccccctctgac
tccaaggaaactactgttactgcaaaggaccctgaaaggccttctggtcaggactggctt
cgggacccacgactgcttaggaggatgggcatgagccctgaagccaaagggaaatgccta
atggatccacagtccttgagcccgcagcatcctggagcaacacctccctcgggagagcca
ggcttccctgtaattcaccaggacgtgggcagcgtgcagcagtccgctgccaaaggagct
accctgagcaaccacaaacctcatgtgcagtgtgatcctccagctgctagtggtgatgct
gccacaagtagaagaaaatgtgaccaggaagggatgctcagctacagaagagagaccagg
gctttcagtgaaggggaccaggagaagtacagctctgtgagccatcacacaaagaggaac
tctggctgggacaaggaggaggaggacagtagttcaaagaagagaaaagttttatag
DBGET
integrated database retrieval system
