Equus asinus (ass): 106845461
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Entry
106845461 CDS
T04645
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
eai
Equus asinus (ass)
Pathway
eai00790
Folate biosynthesis
eai01100
Metabolic pathways
eai01240
Biosynthesis of cofactors
eai01523
Antifolate resistance
eai04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
eai00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
106845461 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
106845461 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
106845461 (FPGS)
Enzymes [BR:
eai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
106845461 (FPGS)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
106845461
NCBI-ProteinID:
XP_014719130
UniProt:
A0A9L0K3N5
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Position
10:complement(15430959..15441153)
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AA seq
588 aa
AA seq
DB search
MSRARSHLRSAFLLAAVSPLSATTRFGARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQTQLEAMELFLARSGLQLEDLDQLNIIHVTGTKGKGSTCAFTERILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTNHFWRLYHRLQETKDGSSCVSMPAYFR
FLTLMAFHIFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGLDHTSLLGDTVEKI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLARCWLQQKDHQGIGELKASQPSLQWQLPLAPVFQPTSHMQHGLRDTE
WPGRTQVLRRGPLTWYLDGAHTVSSVQACVRWFRQALRGRDPPDGGPEVRVLLFNSTGDR
DPAALLKLLQPCQFHYAVFCPNLTEVSPTGNEDQQNFTVTLDQVLLRCLTHQQHWSRLDK
EQASPNLWNSPGPEPGGPASLLLAPCLPHPVSTSSLVFSCISHALQWISQGRDPVFQPPS
PPRGLLAHPVAGSGASVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgcagccacttgcgctcggctttcctcctggctgcggtttctccgctc
agtgcaacgacccgcttcggcgcgcgacgaggattgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactcaacaccctccagaccaacgccagc
tacctggagcaggtgaagcgccagcggggtgaccctcagacacagctggaagccatggag
ctgttcttggcacgcagtgggctacagttggaggacttggaccagctgaacatcattcat
gtcaccgggaccaaggggaagggctccacctgtgccttcactgaacgaatcctccgaagc
tatggcttgaagaccggattctttagctctccccacctggtgcaggtgcgcgagcggatc
cgcatcaacgggcagcccatcagccctgagctcttcaccaaccacttctggcgcctctac
caccggctgcaggagaccaaggatggcagcagctgtgtctccatgcccgcctacttccgc
ttcctcacgctcatggccttccacatcttcctccaagagaaggtggacctggcagtggtg
gaggtgggcatcggtggggcctacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggggtctcctctcttggcctcgaccacaccagccttttgggggacacggtggagaagatt
gcatggcagaaagggggcatcttcaagcgtggtgtccctgccttcaccgtgcttcagcct
gatggtcccctggcagtgctgagggaccgtgcgcagcagatctcatgtcctctctacctg
tgcccacctctggaagccctggaggaaggggggccaccgctgacccttggcctggaggga
gagcaccagcggtccaatgccgccttggccttgcagctggcccgctgctggctgcagcaa
aaggaccaccagggcatcggggagctgaaggcatcccagccgagtctccagtggcagctg
cccctggcacccgtcttccagcccacgtcccacatgcagcacgggcttcgggacacggag
tggcctggccggacgcaggtgctgcggcgcgggccgctcacctggtacctggacggcgcc
cacaccgtcagcagcgtgcaggcctgcgtgcgctggttccgccaggcgctgcgtggccgt
gacccaccggacggtgggcccgaggtgcgtgtcttgctcttcaactctactggggaccgg
gatcccgcggccctgctgaagctgttgcagccctgccagtttcactatgctgttttctgc
cccaacctgacagaggtgtcacccacgggcaacgaagaccagcagaacttcacagtgaca
ctggaccaggtgctgctccgctgcctcacacaccagcagcactggagccgcctggacaag
gagcaggccagcccgaacctctggaacagccccggcccggagcctggtgggcccgcgtcc
ttgctgctggcaccctgcctgccccaccccgtcagcaccagctcccttgtcttcagctgc
atctcccacgccttgcagtggatcagccaaggccgggaccctgtctttcagccacccagt
cccccacggggcctcctcgcccaccccgtggcaggcagcggggccagtgtactgcgggag
gctgctgccatccacgtgctggtcacaggcagcctgcacctggtcgggggtgtcctgaag
ctgctggagccctccctgtcccagtag
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