KEGG   Equus asinus (ass): 106845583
Entry
106845583         CDS       T04645                                 
Symbol
GSTA4
Name
(RefSeq) glutathione S-transferase A4
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
eai  Equus asinus (ass)
Pathway
eai00480  Glutathione metabolism
eai00980  Metabolism of xenobiotics by cytochrome P450
eai00982  Drug metabolism - cytochrome P450
eai00983  Drug metabolism - other enzymes
eai01100  Metabolic pathways
eai01524  Platinum drug resistance
eai05200  Pathways in cancer
eai05204  Chemical carcinogenesis - DNA adducts
eai05207  Chemical carcinogenesis - receptor activation
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05225  Hepatocellular carcinoma
eai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    106845583 (GSTA4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    106845583 (GSTA4)
   00982 Drug metabolism - cytochrome P450
    106845583 (GSTA4)
   00983 Drug metabolism - other enzymes
    106845583 (GSTA4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106845583 (GSTA4)
   05204 Chemical carcinogenesis - DNA adducts
    106845583 (GSTA4)
   05207 Chemical carcinogenesis - receptor activation
    106845583 (GSTA4)
   05208 Chemical carcinogenesis - reactive oxygen species
    106845583 (GSTA4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    106845583 (GSTA4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    106845583 (GSTA4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    106845583 (GSTA4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:eai02000]
    106845583 (GSTA4)
Enzymes [BR:eai01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     106845583 (GSTA4)
Transporters [BR:eai02000]
 Other transporters
  Pores ion channels [TC:1]
   106845583 (GSTA4)
SSDB
Motif
Pfam: GST_C_3 GST_C GST_N GST_C_2 GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 106845583
NCBI-ProteinID: XP_014719370
UniProt: A0A8C4MMK7
LinkDB
Position
8:complement(79714262..79730679)
AA seq 222 aa
MAAKPKLHYPNGRGRMESVRWVLAAAGVEFDEEFLETKDQLQKLQDGNHLLFQQVPMVEI
DGMKLVQTRSILHYIADKHHLFGKDLKERTLIDMYVEGTLDLLELIIMHPFLKPDDQQKE
VVNMAQKAIIRYFPVFEKVLRDHGQRFLVGNQLSLADIILLQTILALEEKIPNILSAFPH
LQEFTVKISNIPTIKKFLEPGSKKKPPPDDIYVRTVYNLFMP
NT seq 669 nt   +upstreamnt  +downstreamnt
atggcagcgaagcccaagctccattatccaaacgggagaggtcggatggaatccgtaaga
tgggttttagccgctgctggagtcgagttcgatgaagaattcttagaaacaaaagatcag
ctgcagaagttgcaggatggtaaccacctgttgttccaacaagtgccgatggttgaaatt
gacgggatgaagctggtgcagacccgcagcatcctccactacatagcggacaagcaccac
ctctttggcaaggacctcaaggagagaaccctgattgacatgtatgtggaggggacgctg
gatctgctggaattgatcatcatgcatcctttcctaaaaccagatgatcagcaaaaagaa
gtggtcaacatggcccagaaggctatcattagatactttcctgtgtttgaaaaggtctta
agggatcacggacaaaggtttcttgttggtaatcagctgagcctcgcggacataattctt
ctccaaaccattttggctctagaagagaaaattcctaatatcctgtctgcatttcctcac
ctccaggagttcaccgtgaaaataagtaatatccctacaattaagaaatttcttgagcct
ggtagcaagaagaagcctcctccggatgacatctacgtgagaaccgtctacaacctcttt
atgccgtaa

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